Biological process: non-membrane spanning protein tyrosine kinase activity^{(2003, 2011, 2017, 2020, 2022, 2024, 2025)} protein tyrosine kinase activity^{(2003, 2005, 2011, 2014, 2016, 2019, 2022, 2024, 2025)} protein kinase activity^{(2003, 2025)} transferase activity⁽²⁰²⁵⁾ nucleotide binding⁽²⁰²⁵⁾ kinase activity⁽²⁰²⁵⁾ ATP binding⁽²⁰²⁵⁾ lipid binding⁽²⁰²⁵⁾ phosphatidylinositol-4,5-bisphosphate binding^{(2009, 2017, 2025)} integrin binding^{(2010, 2016, 2019, 2025)}
± 23 signaling receptor activator activity²⁰²⁵ protein-containing complex binding^{2007, 2010, 2025} neurotransmitter receptor regulator activity^{2024, 2025} molecular function activator activity^{2022, 2025} ionotropic glutamate receptor binding²⁰²⁵ calcium/calmodulin-dependent protein kinase activity^{2014, 2025} protein tyrosine phosphatase activity^{2022, 2025} protein phosphatase binding^{2018, 2025} protein kinase binding^{2011, 2025} identical protein binding²⁰²⁵ actin binding^{2013, 2025} SH2 domain binding^{2005, 2025} JUN kinase binding^{2011, 2025} ubiquitin protein ligase binding^{2017, 2025} phosphatidylinositol 3-kinase binding^{2010, 2025} phosphatase binding^{2017, 2025} glutamate receptor binding^{2024, 2025} enzyme binding^{2016, 2025} 3-phosphoinositide-dependent protein kinase binding^{2006, 2025} signaling receptor binding²⁰²² protein-membrane adaptor activity²⁰²⁰ protease binding²⁰¹⁶ calcium-dependent cysteine-type endopeptidase activity²⁰¹⁶

Molecular function: positive regulation of cell population proliferation^{2003, 2007, 2011, 2016, 2025} signal complex assembly²⁰²⁵ positive regulation of cell migration^{2007, 2008, 2011, 2012, 2023, 2025} regulation of cell adhesion^{2011, 2020, 2025} negative regulation of apoptotic process^{2008, 2011, 2025} integrin-mediated signaling pathway^{2002, 2011, 2014, 2025} epidermal growth factor receptor signaling pathway^{2007, 2017, 2025} regulation of cell shape^{2011, 2025} vascular endothelial growth factor receptor signaling pathway^{2011, 2025} regulation of multicellular organismal process²⁰²⁵
± 180 cell differentiation^{2007, 2025} angiogenesis^{2007, 2011, 2025} signal transduction^{2003, 2018, 2025} positive regulation of ubiquitin-dependent protein catabolic process^{2011, 2025} regulation of G protein-coupled receptor signaling pathway^{2017, 2025} establishment of protein localization to membrane^{2017, 2025} positive regulation of signal transduction²⁰²⁵ positive regulation of endothelial cell migration^{2011, 2012, 2025} positive regulation of cell-matrix adhesion^{2011, 2025} positive regulation of actin filament polymerization^{2011, 2025} positive regulation of JNK cascade^{2011, 2025} positive regulation of ERK1 and ERK2 cascade^{2011, 2025} negative regulation of cell population proliferation^{2011, 2025} immune system process²⁰²⁵ endothelin receptor signaling pathway^{2019, 2025} cell surface receptor signaling pathway^{2011, 2025} adaptive immune response²⁰²⁵ sprouting angiogenesis^{2011, 2025} regulation of release of sequestered calcium ion into cytosol^{2011, 2025} regulation of macrophage chemotaxis^{2011, 2025} regulation of actin cytoskeleton organization^{2023, 2025} positive regulation of B cell chemotaxis^{2011, 2025} negative regulation of bone mineralization^{2011, 2025} cortical cytoskeleton organization^{2023, 2025} chemokine-mediated signaling pathway^{2011, 2025} bone resorption^{2011, 2025} tumor necrosis factor-mediated signaling pathway^{2011, 2025} regulation of ubiquitin-dependent protein catabolic process^{2011, 2025} regulation of postsynaptic density assembly^{2024, 2025} positive regulation of protein metabolic process^{2015, 2025} positive regulation of neuron projection development^{2011, 2025} negative regulation of potassium ion transport^{2011, 2025} negative regulation of myeloid cell differentiation^{2011, 2025} marginal zone B cell differentiation^{2011, 2025} cellular response to retinoic acid^{2011, 2025} positive regulation of angiogenesis^{2011, 2025} establishment of protein localization²⁰²⁵ cell surface receptor protein tyrosine kinase signaling pathway²⁰²⁵ positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction^{2011, 2022, 2023, 2025} regulation of cell differentiation²⁰²⁵ animal organ morphogenesis²⁰²⁵ peptidyl-tyrosine phosphorylation^{2006, 2011, 2017, 2025} positive regulation of cell growth^{2007, 2008, 2025} neuron migration^{2003, 2004, 2024} neuron differentiation²⁰²⁵ regulation of osteoblast differentiation^{2011, 2025} regulation of cell population proliferation^{2011, 2025} positive regulation of protein kinase activity^{2011, 2025} peptidyl-tyrosine autophosphorylation^{2014, 2017, 2025} negative regulation of cell adhesion mediated by integrin²⁰²⁵ ephrin receptor signaling pathway^{2011, 2025} activation of GTPase activity^{2007, 2024, 2025} regulation of focal adhesion assembly^{2011, 2015, 2025} protein autophosphorylation^{2007, 2011, 2016} positive regulation of synaptic transmission, glutamatergic^{2014, 2025} positive regulation of excitatory postsynaptic potential^{2014, 2025} negative regulation of ossification^{2007, 2025} negative regulation of neuron apoptotic process^{2021, 2025} negative regulation of anoikis^{2012, 2016, 2025} long-term synaptic potentiation^{2014, 2025} ionotropic glutamate receptor signaling pathway^{2021, 2025} cellular defense response^{2021, 2025} cell migration^{2002, 2022, 2025} activation of Janus kinase activity^{2007, 2011, 2025} MAPK cascade^{2007, 2008, 2025} transforming growth factor beta receptor signaling pathway^{2014, 2025} regulation of substrate adhesion-dependent cell spreading^{2015, 2025} regulation of modification of postsynaptic actin cytoskeleton²⁰²⁴ regulation of epithelial cell migration^{2015, 2025} postsynaptic modulation of chemical synaptic transmission^{2024, 2025} positive regulation of wound healing^{2019, 2025} positive regulation of synapse structural plasticity^{2009, 2025} positive regulation of macrophage proliferation^{2020, 2025} positive regulation of macrophage chemotaxis^{2020, 2025} positive regulation of fibroblast migration^{2019, 2025} positive regulation of epithelial to mesenchymal transition^{2022, 2025} positive regulation of epithelial cell migration^{2022, 2025} positive regulation of cell-cell adhesion mediated by integrin²⁰²⁵ negative regulation of cell-cell adhesion^{2012, 2025} negative regulation of autophagy²⁰¹⁷ growth hormone receptor signaling pathway^{2011, 2025} actin filament organization^{2007, 2016, 2025} vasodilation^{2008, 2025} vasculogenesis²⁰⁰⁷ system development²⁰²⁵ stress fiber assembly^{2007, 2025} response to xenobiotic stimulus^{2007, 2008} response to mechanical stimulus^{2007, 2008} response to light intensity²⁰²⁴ response to ischemia^{2021, 2025} response to hydrogen peroxide^{2007, 2025} response to glucose^{2007, 2008} response to cation stress^{2021, 2025} regulation of protein localization²⁰²¹ regulation of neurogenesis²⁰²⁵ regulation of cell-matrix adhesion²⁰²⁵ protein transport²⁰²⁴ protein phosphorylation²⁰⁰³ positive regulation of translation^{2007, 2025} positive regulation of synaptic transmission^{2008, 2025} positive regulation of smooth muscle cell proliferation^{2008, 2025} positive regulation of smooth muscle cell migration^{2008, 2025} positive regulation of reactive oxygen species metabolic process^{2007, 2025} positive regulation of phagocytosis^{2008, 2025} positive regulation of nitric-oxide synthase activity^{2015, 2025} positive regulation of nitric oxide biosynthetic process^{2015, 2025} positive regulation of glial cell proliferation^{2008, 2025} positive regulation of cytosolic calcium ion concentration^{2007, 2025} positive regulation of cell adhesion^{2008, 2025} positive regulation of cardiac muscle hypertrophy²⁰¹⁷ positive regulation of JUN kinase activity^{2007, 2025} positive regulation of DNA biosynthetic process^{2015, 2025} oocyte maturation^{2007, 2025} nuclear migration²⁰¹⁷ neuron projection development^{2007, 2025} negative regulation of synapse assembly²⁰¹⁰ negative regulation of organ growth²⁰⁰⁶ negative regulation of muscle cell apoptotic process^{2007, 2025} negative regulation of cell migration^{2008, 2025} negative regulation of axonogenesis²⁰⁰⁷ microtubule cytoskeleton organization²⁰⁰³ long-term synaptic depression^{2015, 2025} light adaption²⁰²⁴ intracellular chloride ion homeostasis^{2008, 2025} focal adhesion assembly^{2006, 2025} extracellular matrix organization²⁰⁰⁵ endothelial cell migration²⁰⁰⁷ cytoskeleton organization²⁰²⁴ central nervous system neuron axonogenesis²⁰⁰⁷ cellular response to transforming growth factor beta stimulus²⁰¹⁴ cellular response to fluid shear stress²⁰¹⁵ cell adhesion^{2007, 2025} blood vessel endothelial cell migration^{2007, 2025} blood vessel development²⁰⁰⁷ JNK cascade^{2008, 2025} Golgi organization²⁰²⁴ wound healing, spreading of cells²⁰¹⁶ vascular endothelial cell response to oscillatory fluid shear stress²⁰²⁵ response to reactive oxygen species²⁰⁰⁷ response to pH²⁰¹⁶ response to muscle stretch²⁰¹⁶ response to immobilization stress²⁰⁰⁷ response to hypoxia²⁰⁰⁷ response to hormone²⁰⁰⁷ response to ethanol²⁰⁰⁷ response to estradiol²⁰⁰⁸ response to cocaine²⁰⁰⁷ response to calcium ion²⁰⁰⁷ response to cAMP²⁰⁰⁷ response to arsenic-containing substance²⁰⁰⁸ regulation of synaptic plasticity²⁰¹⁷ regulation of growth²⁰²⁵ regulation of endothelial cell migration²⁰¹¹ regulation of cytoskeleton organization²⁰¹¹ regulation of cell adhesion mediated by integrin²⁰²⁵ radial glia-guided pyramidal neuron migration²⁰²¹ protein-containing complex assembly²⁰⁰³ protein localization to plasma membrane²⁰²⁰ postsynaptic actin cytoskeleton organization²⁰²⁵ positive regulation of substrate-dependent cell migration, cell attachment to substrate²⁰¹⁶ positive regulation of protein tyrosine kinase activity²⁰¹⁶ positive regulation of protein binding²⁰¹⁶ positive regulation of focal adhesion assembly²⁰¹⁶ placenta development²⁰¹¹ netrin-activated signaling pathway²⁰¹¹ negative regulation of synaptic assembly at neuromuscular junction²⁰¹³ negative regulation of receptor recycling²⁰¹⁸ negative regulation of protein autophosphorylation²⁰¹⁶ negative regulation of cell-substrate adhesion²⁰¹⁶ heart morphogenesis²⁰¹¹ glial cell proliferation²⁰⁰⁷ fat cell differentiation²⁰⁰⁸ establishment of cell polarity²⁰¹¹ detection of muscle stretch²⁰²⁰ cellular response to morphine²⁰²⁴ cell motility²⁰¹¹ axon guidance²⁰¹¹ apoptotic process²⁰⁰³ angiogenesis involved in wound healing²⁰¹⁶ Fc-gamma receptor signaling pathway involved in phagocytosis²⁰²⁵

Cellular component: plasma membrane^{2016, 2017, 2018, 2024, 2025} focal adhesion^{2005, 2007, 2008, 2011, 2014, 2016, 2017, 2025} cell cortex^{2007, 2017, 2018, 2025} cell junction²⁰²⁵ dendritic spine^{2009, 2017, 2025} cytosol^{2011, 2013, 2018, 2024, 2025} glutamatergic synapse^{2024, 2025} cytoplasm^{2003, 2016, 2025} nucleus^{2011, 2015, 2025} perinuclear region of cytoplasm^{2007, 2011, 2015, 2025}
± 31 lamellipodium^{2005, 2011, 2025} postsynapse^{2024, 2025} cell projection^{2018, 2025} protein-containing complex^{2017, 2025} postsynaptic density, intracellular component^{2024, 2025} presynapse^{2024, 2025} cell periphery²⁰²⁵ postsynaptic density^{2014, 2017, 2024, 2025} ciliary basal body^{2020, 2025} apical plasma membrane^{2006, 2008, 2025} cytoskeleton^{2003, 2025} neuronal cell body^{2014, 2025} growth cone^{2021, 2025} dendrite^{2014, 2025} centrosome²⁰²⁵ cell body^{2014, 2018, 2025} apical dendrite^{2014, 2025} NMDA selective glutamate receptor complex^{2014, 2025} stress fiber^{2014, 2025} sarcolemma^{2008, 2016, 2025} Schaffer collateral - CA1 synapse^{2024, 2025} nuclear body^{2008, 2025} intercalated disc^{2008, 2025} basolateral plasma membrane^{2008, 2025} axon^{2007, 2025} type Is terminal bouton²⁰¹² type Ib terminal bouton²⁰¹² tertiary granule membrane²⁰¹⁶ secretory granule membrane²⁰¹⁶ cilium²⁰²⁵ ciliary tip²⁰²⁵