Collated Gene Ontology terms

Biological process: RNA binding(2004, 2006, 2014, 2023) metal ion binding(2023) zinc ion binding(2022, 2023) nucleic acid binding(2014, 2023) sequence-specific double-stranded DNA binding(2020, 2023) enzyme binding(2023) nuclease activity(2023) hydrolase activity(2023) endonuclease activity(2023) RNA endonuclease activity(2006)

Molecular function: mRNA processing2023 mRNA 3'-end processing2023 macromolecule metabolic process2023 mRNA polyadenylation2016, 2018, 2023 polycistronic mRNA processing2014 mRNA metabolic process2023 cellular nitrogen compound metabolic process2023 RNA processing2018, 2022 ubiquitin-dependent protein catabolic process2021 termination of RNA polymerase II transcription, poly(A)-coupled2018
proteasome-mediated ubiquitin-dependent protein catabolic process2021 eye photoreceptor cell development2008 co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway2023

Cellular component: mRNA cleavage and polyadenylation specificity factor complex2004, 2006, 2010, 2012, 2016, 2017, 2018, 2019, 2022, 2023 nucleus2009, 2013, 2017, 2018, 2023 cytosol2009, 2017, 2023 nucleoplasm2018, 2022, 2023 intracellular membrane-bounded organelle2023 cytoplasm2023

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 3/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 6/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 0 2 4 6 8 10 Knownness

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
CPSF4_HUMAN
Ensembl»
1.3
CPSF4 Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa
subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog)		 Homo sapiens
TI:9606 None
 
CPSF4_DROME
FlyBase»
1.3
Clp Cleavage and polyadenylation specificity factor subunit 4 (EC 3.1.-.-)
(Cleavage and polyadenylation specificity factor 30 kDa subunit) (Protein clipper)		 Drosophila melanogaster
TI:7227 None
 
CPSF4_MOUSE
Ensembl»
0.5
Cpsf4 Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity
factor 30 kDa subunit) (CPSF 30 kDa subunit) (Clipper homolog) (Clipper/CPSF 30K)		 Mus musculus
TI:10090 None
 
Q98881_DANRE
ZFIN»
0.8
nar Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30
kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit)		 Danio rerio
TI:7955 None
 
YTH1_YEAST
SGD»
4.4
YTH1 mRNA 3'-end-processing protein YTH1
(Yeast 30 kDa homolog 1)		 Saccharomyces cerevisiae
TI:4932 None
 
CPS4L_HUMAN
Ensembl»
0.0
CPSF4L Putative cleavage and polyadenylation
specificity factor subunit 4-like protein		 Homo sapiens
TI:9606 None
 
CPSF4_RAT
RGD»
0.5
Cpsf4 Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and
polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit)		 Rattus norvegicus
TI:10116 None
 
Q55CA3_DICDI
dictyBase»
0.5
cpsf4 CCCH-type zinc finger-containing protein Dictyostelium discoideum
TI:44689 None
 
Q7YTG9_CAEEL
WormBase»
0.0
cpsf-4 Cleavage and polyadenylation
specificity factor subunit 4		 Caenorhabditis elegans
TI:6239 None
 
YTH1_SCHPO
PomBase»
1.0
yth1 mRNA 3'-end-processing protein yth1 Schizosaccharomyces pombe
TI:4896 None
 
A0A0G2K937_RAT
RGD»
0.0
Cpsf4l Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30
kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit)		 Rattus norvegicus
TI:10116 None
   
A0A8I6A9L9_RAT
RGD»
0.0
LOC100360200 Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30
kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit)		 Rattus norvegicus
TI:10116 None
   
A0A8I6AUI5_RAT
RGD»
0.0
Cpsf4-ps1 Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30
kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit)		 Rattus norvegicus
TI:10116 None
   
A0A8V0ZJP7_CHICK
Ensembl»
0.0
CPSF4 Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30
kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit)		 Gallus gallus
TI:9031 None
   
A0A8V1AMD1_CHICK
Ensembl»
0.0
Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30
kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit)		 Gallus gallus
TI:9031 None
   
E9Q2N0_MOUSE
Ensembl»
0.0
Cpsf4l Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30
kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit)		 Mus musculus
TI:10090 None