Cluster UKP06398
- CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED
Standard knownness: 3.6; Custom knownness: None; Num. species: 61; Orthology database: Panther19.0; Protein members: 83
Collated Gene Ontology terms
Biological process:
RNA binding(2006, 2013, 2014, 2024)
metal ion binding(2024)
zinc ion binding(2022, 2024)
sequence-specific double-stranded DNA binding(2020, 2024)
DNA binding(2024)
enzyme binding(2024)
nucleic acid binding(2014)
endonuclease activity(2024)
RNA endonuclease activity(2006)
Molecular function: mRNA processing2023, 2024 mRNA 3'-end processing2024 polycistronic mRNA processing2014 mRNA metabolic process2024 RNA processing2018, 2022 ubiquitin-dependent protein catabolic process2021 termination of RNA polymerase II transcription, poly(A)-coupled2018 proteasome-mediated ubiquitin-dependent protein catabolic process2021 eye photoreceptor cell development2008 co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway2023
Cellular component: nucleus2009, 2013, 2017, 2018, 2024 mRNA cleavage and polyadenylation specificity factor complex2004, 2006, 2010, 2013, 2016, 2017, 2018, 2019, 2022, 2024 cytosol2009, 2017, 2024 nucleoplasm2018, 2022, 2023, 2024 intracellular membrane-bounded organelle2023, 2024 cytoplasm2024
Phylogenetic distribution
| Chordates: | 22/21 |  |
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 0/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 3/3 | |
| Arthropods: | 5/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 13/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 2/3 | |
| Excavates: | 4/4 | |
| Harosa: | 3/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 6/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 |
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Proteins
| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
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YTH1_YEAST SGD» |
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YTH1 | mRNA 3'-end-processing protein YTH1 (Yeast 30 kDa homolog 1) |
Saccharomyces cerevisiae TI:4932 None |
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CPSF4_DROME FlyBase» |
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Clp | Cleavage and polyadenylation specificity factor subunit 4 (EC 3.1.-.-) (Cleavage and polyadenylation specificity factor 30 kDa subunit) (Protein clipper) |
Drosophila melanogaster TI:7227 None |
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CPSF4_HUMAN Ensembl» |
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CPSF4 | Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog) |
Homo sapiens TI:9606 None |
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YTH1_SCHPO PomBase» |
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yth1 | mRNA 3'-end-processing protein yth1 |
Schizosaccharomyces pombe TI:4896 None |
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Q98881_DANRE ZFIN» |
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nar | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Danio rerio TI:7955 None |
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CPSF4_RAT RGD» |
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Cpsf4 | Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) |
Rattus norvegicus TI:10116 None |
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Q55CA3_DICDI dictyBase» |
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cpsf4 | CCCH-type zinc finger-containing protein |
Dictyostelium discoideum TI:44689 None |
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A0A078IT19_BRANA EnsemblPlants» |
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BnaAnng11340D | BnaAnng11340D protein |
Brassica napus TI:3708 None |
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A0A0G2K937_RAT RGD» |
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Cpsf4l | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Rattus norvegicus TI:10116 None |
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A0A1L8EM14_XENLA Xenbase» |
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cpsf4l.S | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Xenopus laevis TI:8355 None |
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A0A1L8EXA7_XENLA Xenbase» |
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cpsf4.L | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Xenopus laevis TI:8355 None |
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A0A1S4ACR8_TOBAC EnsemblFungi» |
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LOC107796218 | 30-kDa cleavage and polyadenylation specificity factor 30-like |
Nicotiana tabacum TI:4097 None |
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A0A287BMQ8_PIG Ensembl» |
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Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Sus scrofa TI:9823 None |
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A0A2A6C547_PRIPA EnsemblMetazoa» |
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WBGene00096627 | C3H1-type domain-containing protein |
Pristionchus pacificus TI:54126 None |
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A0A2C9VN56_MANES EnsemblPlants» |
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MANES_06G055600 | C3H1-type domain-containing protein |
Manihot esculenta TI:3983 None |
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A0A2I2YK73_GORGO Ensembl» |
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CPSF4L | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Gorilla gorilla TI:9593 None |
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A0A2I3RK59_PANTR Ensembl» |
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CPSF4L | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Pan troglodytes TI:9598 None |
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A0A2K3CN33_CHLRE EnsemblPlants» |
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CHLRE_24g755647v5 | C3H1-type domain-containing protein |
Chlamydomonas reinhardtii TI:3055 None |
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A0A3Q2H6W1_HORSE Ensembl» |
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CPSF4 | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Equus caballus TI:9796 None |
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A0A480Y2Q2_PIG Ensembl» |
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CPSF4 | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Sus scrofa TI:9823 None |
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A0A5F8GQU9_MONDO Ensembl» |
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Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Monodelphis domestica TI:13616 None |
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A0A6I8NJD6_ORNAN Ensembl» |
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Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Ornithorhynchus anatinus TI:9258 None |
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A0A6I8NTJ0_ORNAN Ensembl» |
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CPSF4 | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Ornithorhynchus anatinus TI:9258 None |
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A0A7M7NSC2_STRPU EnsemblMetazoa» |
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Cleavage and polyadenylation specificity factor subunit 4 |
Strongylocentrotus purpuratus TI:7668 None |
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A0A803SMN3_ANOCA Ensembl» |
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cpsf4 | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Anolis carolinensis TI:28377 None |
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A0A8I3N5M4_CANLF Ensembl» |
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CPSF4 | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Canis lupus TI:9612 None |
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A0A8I3S188_CANLF Ensembl» |
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Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Canis lupus TI:9612 None |
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A0A8I6AUI5_RAT RGD» |
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Cpsf4-ps1 | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Rattus norvegicus TI:10116 None |
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A0A8R1Y6P1_PRIPA EnsemblMetazoa» |
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WBGene00092888 | Cleavage and polyadenylation specificity factor subunit 4 |
Pristionchus pacificus TI:54126 None |
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A0A8V0ZJP7_CHICK Ensembl» |
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CPSF4 | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Gallus gallus TI:9031 None |
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A0A8V1AMD1_CHICK Ensembl» |
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Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Gallus gallus TI:9031 None |
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A0A9J7NB40_BRAFL CTD» |
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LOC118429553 | Cleavage and polyadenylation specificity factor subunit 4 |
Branchiostoma floridae TI:7739 None |
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A0D6V7_PARTE EnsemblProtists» |
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GSPATT00001815001 | Chromosome undetermined scaffold_4, whole genome shotgun sequence |
Paramecium tetraurelia TI:5888 None |
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A0DK00_PARTE EnsemblProtists» |
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GSPATT00017711001 | Chromosome undetermined scaffold_53, whole genome shotgun sequence |
Paramecium tetraurelia TI:5888 None |
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A2DBS7_TRIV3 VEuPathDB» |
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TVAG_094550 | C3H1-type domain-containing protein |
Trichomonas vaginalis TI:5722 None |
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A2EAT1_TRIV3 VEuPathDB» |
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TVAG_047060 | C3H1-type domain-containing protein |
Trichomonas vaginalis TI:5722 None |
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A7EKP8_SCLS1 EnsemblFungi» |
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SS1G_05895 | mRNA 3'-end-processing protein |
Sclerotinia sclerotiorum TI:5180 None |
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A7S8B4_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g35001 | C3H1-type domain-containing protein |
Nematostella vectensis TI:45351 None |
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A8BFA9_GIAIC EnsemblProtists» |
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GL50803_0013225 GL50803_13225 | YTH1 family protein (Zinc finger domain protein) |
Giardia intestinalis TI:5741 None |
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A8X0L5_CAEBR WormBase» |
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mig-32 | Cleavage and polyadenylation specificity factor subunit 4 (EC 2.3.2.27) |
Caenorhabditis briggsae TI:6238 None |
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B3RPS1_TRIAD EnsemblMetazoa» |
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TRIADDRAFT_53642 | Cleavage and polyadenylation specificity factor subunit 4 |
Trichoplax adhaerens TI:10228 None |
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B6JVW0_SCHJY EnsemblFungi» |
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SJAG_00527 | mRNA 3'-end-processing protein |
Schizosaccharomyces japonicus TI:4897 None |
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B7Q714_IXOSC EnsemblMetazoa» |
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8036848 | Cleavage and polyadenylation specificity factor subunit 4 |
Ixodes scapularis TI:6945 None |
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B8C4J7_THAPS EnsemblProtists» |
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THAPSDRAFT_19126 | C3H1-type domain-containing protein |
Thalassiosira pseudonana TI:35128 None |
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C4M9G4_ENTH1 EnsemblProtists» |
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EHI_067580 | Zinc finger protein, putative |
Entamoeba histolytica TI:5759 None |
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CPS4L_HUMAN Ensembl» |
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CPSF4L | Putative cleavage and polyadenylation specificity factor subunit 4-like protein |
Homo sapiens TI:9606 None |
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CPSF4_BOVIN Ensembl» |
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CPSF4 | Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) |
Bos taurus TI:9913 None |
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CPSF4_MOUSE Ensembl» |
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Cpsf4 | Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (Clipper homolog) (Clipper/CPSF 30K) |
Mus musculus TI:10090 None |
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CPSF4_XENLA Xenbase» |
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cpsf4 | Cleavage and polyadenylation specificity factor subunit 4 |
Xenopus laevis TI:8355 None |
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CPSF4_XENTR Xenbase» |
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cpsf4 | Cleavage and polyadenylation specificity factor subunit 4 |
Xenopus tropicalis TI:8364 None |
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D6WBZ0_TRICA EnsemblMetazoa» |
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GLEAN_05002 | Cleavage and polyadenylation specificity factor subunit 4 |
Tribolium castaneum TI:7070 None |
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D6WGD0_TRICA EnsemblMetazoa» |
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AUGUSTUS-3.0.2_10339 | Cleavage and polyadenylation specificity factor subunit 4 |
Tribolium castaneum TI:7070 None |
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E3KBS3_PUCGT EnsemblFungi» |
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PGTG_07785 | mRNA 3'-end-processing protein |
Puccinia graminis TI:5297 None |
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E9GIQ6_DAPPU EnsemblMetazoa» |
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DAPPUDRAFT_51128 | Cleavage and polyadenylation specificity factor subunit 4 |
Daphnia pulex TI:6669 None |
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E9Q2N0_MOUSE Ensembl» |
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Cpsf4l | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Mus musculus TI:10090 None |
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F2EIS5_HORVV EnsemblPlants» |
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Predicted protein |
Hordeum vulgare TI:4513 None |
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F4P3G1_BATDJ EnsemblBacteria» |
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BATDEDRAFT_5960 | mRNA 3'-end-processing protein |
Batrachochytrium dendrobatidis TI:109871 None |
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F5HKN3_ANOGA EnsemblMetazoa» |
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11175715 | Cleavage and polyadenylation specificity factor subunit 4 |
Anopheles gambiae TI:7165 None |
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F6QYI7_MACMU Ensembl» |
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CPSF4 | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Macaca mulatta TI:9544 None |
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F6U107_MONDO Ensembl» |
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Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Monodelphis domestica TI:13616 None |
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F7CXF4_MACMU Ensembl» |
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CPSF4L | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Macaca mulatta TI:9544 None |
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F7FVV8_MONDO Ensembl» |
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CPSF4 | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Monodelphis domestica TI:13616 None |
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G3RGL8_GORGO Ensembl» |
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CPSF4 | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Gorilla gorilla TI:9593 None |
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H2MF66_ORYLA Ensembl» |
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cpsf4 | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Oryzias latipes TI:8090 None |
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H2QV04_PANTR Ensembl» |
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CPSF4 | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Pan troglodytes TI:9598 None |
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H2XUQ0_CIOIN Ensembl» |
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Cleavage and polyadenylation specificity factor subunit 4 |
Ciona intestinalis TI:7719 None |
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H3GWX4_PHYRM EnsemblProtists» |
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Cleavage and polyadenylation specificity factor subunit 4 |
Phytophthora ramorum TI:164328 None |
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M1BW73_SOLTU EnsemblPlants» |
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Isoform 2 of Cleavage and polyadenylation specificity factor CPSF30 |
Solanum tuberosum TI:4113 None |
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M3W2R8_FELCA Ensembl» |
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CPSF4L | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Felis catus TI:9685 None |
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M3WLW1_FELCA Ensembl» |
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CPSF4 | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Felis catus TI:9685 None |
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Q28DB2_XENTR Xenbase» |
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cpsf4l | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Xenopus tropicalis TI:8364 None |
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Q28FZ4_XENTR Xenbase» |
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cpsf4 | Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Xenopus tropicalis TI:8364 None |
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Q382Q6_TRYB2 VEuPathDB» |
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Tb11.01.4600 | Cleavage and polyadenylation specificity factor 30 kDa subunit |
Trypanosoma brucei TI:5691 None |
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Q4QHV2_LEIMA EnsemblProtists» |
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LMJF_09_0720 | Putative cleavage and polyadenylation specificity factor 30 kDa subunit |
Leishmania major TI:5664 None |
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Q7YTG9_CAEEL WormBase» |
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cpsf-4 | Cleavage and polyadenylation specificity factor subunit 4 |
Caenorhabditis elegans TI:6239 None |
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W5MBM3_LEPOC Ensembl» |
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Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit) |
Lepisosteus oculatus TI:7918 None |
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YTH1_ASHGO EnsemblFungi» |
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YTH1 | mRNA 3'-end-processing protein YTH1 |
Ashbya gossypii TI:33169 None |
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YTH1_ASPFU EnsemblFungi» |
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yth1 | mRNA 3'-end-processing protein yth1 |
Aspergillus fumigatus TI:746128 None |
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YTH1_CANAL EnsemblFungi» |
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YTH1 | mRNA 3'-end-processing protein YTH1 |
Candida albicans TI:5476 None |
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YTH1_CRYNJ EnsemblFungi» |
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YTH1 | mRNA 3'-end-processing protein YTH1 |
Cryptococcus neoformans TI:5207 None |
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YTH1_EMENI EnsemblFungi» |
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yth1 | mRNA 3'-end-processing protein yth1 |
Emericella nidulans TI:162425 None |
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YTH1_NEUCR EnsemblFungi» |
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yth-1 | mRNA 3'-end-processing protein yth-1 |
Neurospora crassa TI:5141 None |
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YTH1_YARLI EnsemblFungi» |
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YTH1 | mRNA 3'-end-processing protein YTH1 |
Yarrowia lipolytica TI:4952 None |
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