Collated Gene Ontology terms

Biological process: RNA binding(2006, 2013, 2014, 2025) zinc ion binding(2022, 2025) metal ion binding(2025) nucleic acid binding(2014, 2025) sequence-specific double-stranded DNA binding(2020, 2025) enzyme binding(2025) proton-transporting ATPase activity, rotational mechanism(2021) nuclease activity(2025) hydrolase activity(2025) endonuclease activity(2025)
RNA endonuclease activity2006 DNA binding2025

Molecular function: mRNA processing2023, 2025 mRNA 3'-end processing2025 termination of RNA polymerase II transcription, poly(A)-coupled2025 polycistronic mRNA processing2014 embryonic body morphogenesis2018 RNA processing2018, 2022 response to xenobiotic stimulus2014 regulation of gene expression2025 regulation of RNA metabolic process2025 proton transmembrane transport2025
eye photoreceptor cell development2008 co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway2023

Cellular component: nucleus2009, 2013, 2017, 2025 mRNA cleavage and polyadenylation specificity factor complex2004, 2006, 2010, 2013, 2016, 2017, 2018, 2019, 2022, 2025 nucleoplasm2018, 2022, 2024, 2025 cytosol2009, 2017, 2025 cytoplasm2025 PcG protein complex2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 4/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 6/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A8I6AUI5_RAT
RGD»
0.0
Cpsf4-ps1 Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30
kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit)		 Rattus norvegicus
TI:10116 None
   
A0A8V0ZJP7_CHICK
Ensembl»
0.0
CPSF4 Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30
kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit)		 Gallus gallus
TI:9031 None
   
A0A8V1AMD1_CHICK
Ensembl»
0.0
Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30
kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit)		 Gallus gallus
TI:9031 None
   
A0ABK0LZV4_RAT
RGD»
0.0
Cpsf4l Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30
kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit)		 Rattus norvegicus
TI:10116 None
   
CPS4L_HUMAN
Ensembl»
0.0
CPSF4L Putative cleavage and polyadenylation
specificity factor subunit 4-like protein		 Homo sapiens
TI:9606 None
 
CPSF4_DROME
FlyBase»
1.3
Clp Cleavage and polyadenylation specificity factor subunit 4 (EC 3.1.-.-)
(Cleavage and polyadenylation specificity factor 30 kDa subunit) (Protein clipper)		 Drosophila melanogaster
TI:7227 None
 
CPSF4_HUMAN
Ensembl»
2.1
CPSF4 Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa
subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog)		 Homo sapiens
TI:9606 None
 
CPSF4_MOUSE
Ensembl»
1.0
Cpsf4 Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity
factor 30 kDa subunit) (CPSF 30 kDa subunit) (Clipper homolog) (Clipper/CPSF 30K)		 Mus musculus
TI:10090 None
 
CPSF4_RAT
RGD»
1.0
Cpsf4 Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and
polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit)		 Rattus norvegicus
TI:10116 None
 
G3UWW6_MOUSE
Ensembl»
0.0
Cpsf4l Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30
kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit)		 Mus musculus
TI:10090 None
   
Q55CA3_DICDI
dictyBase»
0.5
cpsf4 CCCH-type zinc finger-containing protein Dictyostelium discoideum
TI:44689 None
 
Q7YTG9_CAEEL
WormBase»
0.0
cpsf-4 Cleavage and polyadenylation
specificity factor subunit 4		 Caenorhabditis elegans
TI:6239 None
 
Q98881_DANRE
ZFIN»
0.8
cpsf4 Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30
kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit)		 Danio rerio
TI:7955 None
 
YTH1_SCHPO
PomBase»
1.6
yth1 mRNA 3'-end-processing protein yth1 Schizosaccharomyces pombe
TI:4896 None
 
YTH1_YEAST
SGD»
3.6
YTH1 mRNA 3'-end-processing protein YTH1
(Yeast 30 kDa homolog 1)		 Saccharomyces cerevisiae
TI:4932 None