Collated Gene Ontology terms

Biological process: double-stranded telomeric DNA binding(2010, 2015, 2019, 2024) telomerase activity(2015, 2019, 2024) ankyrin repeat binding(2016, 2019, 2024) G-rich strand telomeric DNA binding(2016, 2019, 2024) DNA binding, bending(2008, 2019, 2024) telomeric DNA binding(2015, 2017, 2024) DNA binding(2002, 2024) protein homodimerization activity(2008, 2010, 2024) microtubule binding(2006, 2019, 2024) identical protein binding(2019, 2024)
sequence-specific DNA binding2019, 2024 RNA polymerase II transcription regulatory region sequence-specific DNA binding2017, 2024 DNA-binding transcription activator activity, RNA polymerase II-specific2020, 2024 transcription coregulator activity2018

Molecular function: telomere maintenance via telomerase2006, 2015, 2019, 2024 negative regulation of telomeric D-loop disassembly2017, 2019, 2024 negative regulation of DNA replication2008, 2019, 2024 telomere maintenance2015, 2024 negative regulation of exonuclease activity2017, 2024 telomere capping2018, 2019, 2024 negative regulation of telomere maintenance via telomerase2008, 2017, 2024 telomeric D-loop disassembly2022, 2024 positive regulation of shelterin complex assembly2015, 2024 negative regulation of establishment of protein localization to telomere2015, 2024
negative regulation of establishment of RNA localization to telomere2016, 2024 meiotic telomere clustering2015, 2024 telomeric loop formation2017 positive regulation of transcription by RNA polymerase II2024 positive regulation of telomere maintenance2018, 2019 cell division2024 t-circle formation2017 response to xenobiotic stimulus2010 regulation of transcription by RNA polymerase II2020 negative regulation of telomere maintenance via telomere lengthening2017 negative regulation of telomere maintenance via semi-conservative replication2008 negative regulation of establishment of protein-containing complex localization to telomere2018

Cellular component: nucleus2002, 2006, 2008, 2009, 2015, 2016, 2024 nuclear telomere cap complex2008, 2019, 2024 chromosome, telomeric region2015, 2022, 2024 shelterin complex2015, 2017, 2018, 2019, 2024 nucleolus2015, 2017, 2024 nuclear body2023, 2024 fibrillar center2023, 2024 spindle2006, 2024 chromosome2024 nucleoplasm2010, 2013
cytoskeleton2024 cytoplasm2024 chromatin2015, 2024

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 0/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 1/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 9/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 1/3 
Excavates: 1/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 1/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

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Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 10 20 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
TERF1_HUMAN
Ensembl»
26.8
TERF1 Telomeric repeat-binding factor 1 (NIMA-interacting protein 2)
(TTAGGG repeat-binding factor 1) (Telomeric protein Pin2/TRF1)		 Homo sapiens
TI:9606 None
 
TERF1_MOUSE
Ensembl»
4.0
Terf1 Telomeric repeat-binding factor 1
(TTAGGG repeat-binding factor 1)		 Mus musculus
TI:10090 None
 
A0A8M9PXV3_DANRE
CTD»
5.3
terf1 Telomeric repeat-binding factor Danio rerio
TI:7955 None
   
A0A8V0XEG3_CHICK
Ensembl»
0.0
TERF1 Telomeric repeat-binding factor Gallus gallus
TI:9031 None
   
A6JFC1_RAT
RGD»
15.3
Terf1 Telomeric repeat-binding factor Rattus norvegicus
TI:10116 None
 
TEB1_SCHPO
PomBase»
4.8
teb1 Telobox protein 1 (Meiotically
up-regulated gene 152 protein)		 Schizosaccharomyces pombe
TI:4896 None