Collated Gene Ontology terms

Biological process: double-stranded telomeric DNA binding(2010, 2015, 2019, 2024) telomerase activity(2015, 2019, 2024) ankyrin repeat binding(2016, 2019, 2024) G-rich strand telomeric DNA binding(2016, 2019, 2024) DNA binding, bending(2008, 2019, 2024) telomeric DNA binding(2015, 2017, 2024) DNA binding(2002, 2024) protein homodimerization activity(2008, 2010, 2024) microtubule binding(2006, 2019, 2024) identical protein binding(2019, 2024)
sequence-specific DNA binding2019, 2024 RNA polymerase II transcription regulatory region sequence-specific DNA binding2017, 2024 DNA-binding transcription activator activity, RNA polymerase II-specific2020, 2024 transcription coregulator activity2018

Molecular function: telomere maintenance via telomerase2006, 2015, 2019, 2024 negative regulation of telomeric D-loop disassembly2017, 2019, 2024 negative regulation of DNA replication2008, 2019, 2024 telomere maintenance2015, 2024 negative regulation of exonuclease activity2017, 2024 telomere capping2018, 2019, 2024 negative regulation of telomere maintenance via telomerase2008, 2017, 2024 telomeric D-loop disassembly2022, 2024 positive regulation of shelterin complex assembly2015, 2024 negative regulation of establishment of protein localization to telomere2015, 2024
negative regulation of establishment of RNA localization to telomere2016, 2024 meiotic telomere clustering2015, 2024 telomeric loop formation2017 positive regulation of transcription by RNA polymerase II2024 positive regulation of telomere maintenance2018, 2019 cell division2024 t-circle formation2017 response to xenobiotic stimulus2010 regulation of transcription by RNA polymerase II2020 negative regulation of telomere maintenance via telomere lengthening2017 negative regulation of telomere maintenance via semi-conservative replication2008 negative regulation of establishment of protein-containing complex localization to telomere2018

Cellular component: nucleus2002, 2006, 2008, 2009, 2015, 2016, 2024 nuclear telomere cap complex2008, 2019, 2024 chromosome, telomeric region2015, 2022, 2024 shelterin complex2015, 2017, 2018, 2019, 2024 nucleolus2015, 2017, 2024 nuclear body2023, 2024 fibrillar center2023, 2024 spindle2006, 2024 chromosome2024 nucleoplasm2010, 2013
cytoskeleton2024 cytoplasm2024 chromatin2015, 2024

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 0/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 1/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 9/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 1/3 
Excavates: 1/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 1/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 10 20 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
TERF1_HUMAN
Ensembl»
26.8
TERF1 Telomeric repeat-binding factor 1 (NIMA-interacting protein 2)
(TTAGGG repeat-binding factor 1) (Telomeric protein Pin2/TRF1)		 Homo sapiens
TI:9606 None
 
A6JFC1_RAT
RGD»
15.3
Terf1 Telomeric repeat-binding factor Rattus norvegicus
TI:10116 None
 
A0A8M9PXV3_DANRE
CTD»
5.3
terf1 Telomeric repeat-binding factor Danio rerio
TI:7955 None
   
TEB1_SCHPO
PomBase»
4.8
teb1 Telobox protein 1 (Meiotically
up-regulated gene 152 protein)		 Schizosaccharomyces pombe
TI:4896 None
 
TERF1_MOUSE
Ensembl»
4.0
Terf1 Telomeric repeat-binding factor 1
(TTAGGG repeat-binding factor 1)		 Mus musculus
TI:10090 None
 
A0A287ALL2_PIG
Ensembl»
0.0
TERF1 Telomeric repeat-binding factor Sus scrofa
TI:9823 None
 
A0A2I2YYC2_GORGO
Ensembl»
0.0
Telomeric repeat-binding factor Gorilla gorilla
TI:9593 None
 
A0A2I2Z249_GORGO
Ensembl»
0.0
Telomeric repeat-binding factor Gorilla gorilla
TI:9593 None
 
A0A2I3RLC2_PANTR
Ensembl»
0.0
Telomeric repeat-binding factor Pan troglodytes
TI:9598 None
 
A0A2I3RXH0_PANTR
Ensembl»
0.0
Telomeric repeat-binding factor Pan troglodytes
TI:9598 None
 
A0A2I3T0Y5_PANTR
Ensembl»
0.0
Telomeric repeat-binding factor Pan troglodytes
TI:9598 None
 
A0A3B3HU23_ORYLA
Ensembl»
0.0
terf1 Telomeric repeat-binding factor Oryzias latipes
TI:8090 None
   
A0A3P6BBB7_BRACM
EnsemblPlants»
0.0
BRAA07T29541Z BRAPAZ1V2_A07P20130.2 Myb-like domain-containing protein Brassica campestris
TI:3711 None
 
A0A3Q2GUN6_HORSE
Ensembl»
0.0
TERF1 Telomeric repeat-binding factor Equus caballus
TI:9796 None
   
A0A6I8PEX1_ORNAN
Ensembl»
0.0
TERF1 Telomeric repeat-binding factor Ornithorhynchus anatinus
TI:9258 None
   
A0A8I3PZA1_CANLF
Ensembl»
0.0
TERF1 Telomeric repeat-binding factor Canis lupus
TI:9612 None
   
A0A8J1L0B1_XENLA
Xenbase»
0.0
LOC108705907 Telomeric repeat-binding factor 1-like Xenopus laevis
TI:8355 None
   
A0A8J1L1I6_XENLA
Xenbase»
0.0
LOC108704836 Telomeric repeat-binding factor 1-like Xenopus laevis
TI:8355 None
   
A0A8V0XEG3_CHICK
Ensembl»
0.0
TERF1 Telomeric repeat-binding factor Gallus gallus
TI:9031 None
   
A2DM85_TRIV3
VEuPathDB»
0.0
TVAG_083580 Myb-like DNA-binding domain containing protein Trichomonas vaginalis
TI:5722 None
 
A2EE65_TRIV3
VEuPathDB»
0.0
TVAG_180360 Myb-like domain-containing protein Trichomonas vaginalis
TI:5722 None
 
A7F6E5_SCLS1
EnsemblFungi»
0.0
SS1G_13174 Uncharacterized protein Sclerotinia sclerotiorum
TI:5180 None
 
A9V2S9_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_32971 Myb-like domain-containing protein Monosiga brevicollis
TI:81824 None
 
B3S2Y4_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_28428 Uncharacterized protein Trichoplax adhaerens
TI:10228 None
 
B6JZ90_SCHJY
EnsemblFungi»
0.0
SJAG_01916 Myb family protein Schizosaccharomyces japonicus
TI:4897 None
 
B7PVK2_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW007708 HTH myb-type domain-containing protein Ixodes scapularis
TI:6945 None
 
B8BQA6_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_1217 Uncharacterized protein Thalassiosira pseudonana
TI:35128 None
 
B8C040_THAPS
EnsemblProtists»
0.0
MYB1 MYB DNA binding
protein/ transcription factor-like protein		 Thalassiosira pseudonana
TI:35128 None
 
B8QB43_XENTR
Xenbase»
0.0
terf1 Telomeric repeat-binding factor Xenopus tropicalis
TI:8364 None
 
C4LSY4_ENTH1
EnsemblProtists»
0.0
EHI_148140 Myb family DNA-binding domain containing protein Entamoeba histolytica
TI:5759 None
 
C4M1I9_ENTH1
EnsemblProtists»
0.0
EHI_001090 Myb family DNA-binding domain containing protein Entamoeba histolytica
TI:5759 None
 
C4M1J1_ENTH1
EnsemblProtists»
0.0
EHI_001110 Myb family DNA-binding domain containing protein Entamoeba histolytica
TI:5759 None
 
F4NTJ3_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_22280 Uncharacterized protein Batrachochytrium dendrobatidis
TI:109871 None
 
F6XW10_MONDO
Ensembl»
0.0
TERF1 Telomeric repeat-binding factor Monodelphis domestica
TI:13616 None
   
F6YGY7_CIOIN
Ensembl»
0.0
Uncharacterized protein Ciona intestinalis
TI:7719 None
 
F7EB98_MACMU
Ensembl»
0.0
TERF1 Telomeric repeat-binding factor Macaca mulatta
TI:9544 None
   
G1KPX9_ANOCA
Ensembl»
0.0
TERF1 Telomeric repeat-binding factor Anolis carolinensis
TI:28377 None
   
G3SB61_GORGO
Ensembl»
0.0
Telomeric repeat-binding factor Gorilla gorilla
TI:9593 None
 
G3SHY3_GORGO
Ensembl»
0.0
TERF1 Telomeric repeat-binding factor Gorilla gorilla
TI:9593 None
 
H2R473_PANTR
Ensembl»
0.0
TERF1 Telomeric repeat-binding factor Pan troglodytes
TI:9598 None
 
H3GLN1_PHYRM
EnsemblProtists»
0.0
Myb-like domain-containing protein Phytophthora ramorum
TI:164328 None
 
M3XBD0_FELCA
Ensembl»
0.0
TERF1 Telomeric repeat-binding factor Felis catus
TI:9685 None
 
Q3MHY0_BOVIN
Ensembl»
0.0
TERF1 Telomeric repeat-binding factor Bos taurus
TI:9913 None
 
Q4WWS2_ASPFU
EnsemblFungi»
0.0
AFUA_3G06870 MYB DNA-binding domain protein Aspergillus fumigatus
TI:746128 None
 
Q5B3T3_EMENI
EnsemblFungi»
0.0
ANIA_04797 Myb-like transcription factor (Eurofung) Emericella nidulans
TI:162425 None
 
Q71E47_XENLA
Xenbase»
0.0
terf1.L Telomeric repeat-binding factor Xenopus laevis
TI:8355 None
 
Q7SE02_NEUCR
EnsemblFungi»
0.0
NCU02182 MYB DNA-binding domain-containing protein Neurospora crassa
TI:5141 None
 
T1EIM8_HELRO
EnsemblMetazoa»
0.0
20196428 Uncharacterized protein Helobdella robusta
TI:6412 None
 
T1EZL9_HELRO
EnsemblMetazoa»
0.0
20202019 Uncharacterized protein Helobdella robusta
TI:6412 None
 
TAY1_YARLI
EnsemblFungi»
0.0
TAY1 telomere-associated protein 1 Yarrowia lipolytica
TI:4952 None
 
W5M814_LEPOC
Ensembl»
0.0
Telomeric repeat-binding factor Lepisosteus oculatus
TI:7918 None