Collated Gene Ontology terms

Biological process: RNA binding(2025) transferase activity(2025) protein-lysine-acetyltransferase activity(2025) mRNA binding(2018) acyltransferase activity(2025)

Molecular function: mRNA export from nucleus2009, 2013, 2017, 2024, 2025 mRNA transport2025 mRNA processing2025 RNA splicing2025 regulatory ncRNA-mediated gene silencing2010, 2025 transcription elongation by RNA polymerase II2024 ta-siRNA processing2010 poly(A)+ mRNA export from nucleus2023 piRNA processing2024 DNA-templated transcription2025

Cellular component: THO complex part of transcription export complex2013, 2017, 2025 nuclear speck2025 transcription export complex2009, 2016, 2018, 2025 nucleoplasm2015, 2024, 2025 chromosome, telomeric region2016, 2025 THO complex2013, 2014, 2025 nucleus2025 cytoplasm2018 Cul4-RING E3 ubiquitin ligase complex2008

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 1/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
THOC3_MOUSE
Ensembl»
1.0
Thoc3 THO complex subunit 3 (Tho3) Mus musculus
TI:10090 None
 
THOC3_HUMAN
Ensembl»
1.9
THOC3 THO complex subunit 3
(Tho3) (TEX1 homolog) (hTREX45)		 Homo sapiens
TI:9606 None
 
THOC3_ARATH
TAIR»
2.1
THO3 THO complex subunit 3 (TEX1 homolog) (AtTEX1) Arabidopsis thaliana
TI:3702 None
 
THOC3_BOVIN
Ensembl»
0.0
THOC3 THO complex subunit 3 (Tho3) Bos taurus
TI:9913 None
 
A0A1D5QGW8_MACMU
Ensembl»
0.0
THOC3 THO complex subunit 3 Macaca mulatta
TI:9544 None
 
A0A6I8PA65_ORNAN
Ensembl»
0.0
THOC3 THO complex subunit 3 Ornithorhynchus anatinus
TI:9258 None
   
A0A8I3NMM3_CANLF
Ensembl»
0.0
THOC3 THO complex subunit 3 Canis lupus
TI:9612 None
   
A0A8V0YNZ7_CHICK
Ensembl»
0.5
THOC3 THO complex subunit 3 Gallus gallus
TI:9031 None
   
F1S386_PIG
Ensembl»
0.0
THOC3 THO complex subunit 3 Sus scrofa
TI:9823 None
 
F7BAN6_HORSE
Ensembl»
0.0
THOC3 THO complex subunit 3 Equus caballus
TI:9796 None
   
F7CHT4_MONDO
Ensembl»
0.0
THOC3 THO complex subunit 3 Monodelphis domestica
TI:13616 None
   
H2R3N4_PANTR
Ensembl»
0.0
THOC3 THO complex subunit 3 Pan troglodytes
TI:9598 None
 
TEX1_YEAST
SGD»
3.2
TEX1 Protein TEX1 (Trex component 1) Saccharomyces cerevisiae
TI:4932 None
 
A0A1L8GXT0_XENLA
Xenbase»
0.0
thoc3.L THO complex subunit 3 Xenopus laevis
TI:8355 None
   
A0A3B3IEH8_ORYLA
Ensembl»
0.0
THOC3 THO complex subunit 3 Oryzias latipes
TI:8090 None
   
A0A8J0R2M6_XENTR
Xenbase»
0.0
thoc3 THO complex subunit 3 Xenopus tropicalis
TI:8364 None
   
G3R8W2_GORGO
Ensembl»
0.0
LOC101131460 THO complex subunit 3 Gorilla gorilla
TI:9593 None
 
Q6AXK9_DANRE
ZFIN»
0.5
thoc3 THO complex subunit 3 Danio rerio
TI:7955 None
 
W5N0W1_LEPOC
Ensembl»
0.0
THO complex subunit 3 Lepisosteus oculatus
TI:7918 None
 
A0ABZ3NNN9_RAT
RGD»
0.5
Thoc3 THO complex subunit 3 Rattus norvegicus
TI:10116 None
   
B7QI45_IXOSC
EnsemblMetazoa»
0.0
8041598 THO complex subunit, putative (EC 2.3.1.48) Ixodes scapularis
TI:6945 None
 
Q9VHT2_DROME
FlyBase»
1.7
tex FI07663p (Tex) Drosophila melanogaster
TI:7227 None
 
THOC3_SCHPO
PomBase»
1.5
THO3 THO complex subunit Tho3 Schizosaccharomyces pombe
TI:4896 None
 
A0A1S3WXS2_TOBAC
euHCVdb»
0.0
LOC107759125 THO complex subunit 3 Nicotiana tabacum
TI:4097 None
   
A0A1S3Z9Z1_TOBAC
euHCVdb»
0.0
LOC107784599 THO complex subunit 3 Nicotiana tabacum
TI:4097 None
   
A0A1U8J8G0_GOSHI
euHCVdb»
0.0
LOC107903400 THO complex subunit 3 Gossypium hirsutum
TI:3635 None
   
A0A1U8LV82_GOSHI
euHCVdb»
0.0
LOC107931189 THO complex subunit 3 Gossypium hirsutum
TI:3635 None
   
A0A2R6WY31_MARPO
euHCVdb»
0.0
MARPO_0049s0058 Uncharacterized protein Marchantia polymorpha
TI:3197 None
 
A0A804JSS2_MUSAM
EnsemblPlants»
0.0
GSMUA_48570.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0A804Q9Y0_MAIZE
EnsemblPlants»
0.0
THO complex subunit 3 Zea mays
TI:4577 None
   
A0A8I6Y0I8_HORVV
EnsemblPlants»
0.0
LOC123398371 Anaphase-promoting complex subunit
4 WD40 domain-containing protein		 Hordeum vulgare
TI:4513 None
   
A0A9R0HSE3_SPIOL
euHCVdb»
0.0
LOC110775856 THO complex subunit 3 Spinacia oleracea
TI:3562 None
   
A9TTX0_PHYPA
EnsemblPlants»
0.0
LOC112292071 Anaphase-promoting complex subunit
4 WD40 domain-containing protein		 Physcomitrium patens
TI:3218 None
 
C5X8Y2_SORBI
euHCVdb»
0.0
SORBI_3002G160700 Uncharacterized protein Sorghum bicolor
TI:4558 None
 
I1IP80_BRADI
EnsemblPlants»
0.0
LOC100838230 Uncharacterized protein Brachypodium distachyon
TI:15368 None
 
K3ZV23_SETIT
EnsemblPlants»
0.0
LOC101755743 Uncharacterized protein Setaria italica
TI:4555 None
 
P91867_CAEEL
WormBase»
0.5
thoc-3 WD_REPEATS_REGION domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q69VQ7_ORYSJ
euHCVdb»
0.0
Os09g0298400 Os09g0298400 protein Oryza sativa
TI:4530 None
 
U5D9B9_AMBTC
euHCVdb»
0.0
AMTR_s00061p00102140 Uncharacterized protein Amborella trichopoda
TI:13333 None
 
A0A022QYR7_ERYGU
neXtProt»
0.0
MIMGU_mgv1a0114402mg Uncharacterized protein Erythranthe guttata
TI:4155 None
 
A0A061FBI7_THECC
neXtProt»
0.0
TCM_030526 Transducin/WD40 repeat-like superfamily protein Theobroma cacao
TI:3641 None
 
A0A067G327_CITSI
euHCVdb»
0.0
CISIN_1g0213191mg Uncharacterized protein Citrus sinensis
TI:2711 None
 
A0A078FW55_BRANA
euHCVdb»
0.0
BnaA10g10280D BnaA10g10280D protein Brassica napus
TI:3708 None
 
A0A078J1Z0_BRANA
euHCVdb»
0.0
BnaCnng32010D BnaCnng32010D protein Brassica napus
TI:3708 None
 
A0A0A0L651_CUCSA
euHCVdb»
0.0
Csa_3G061010 Uncharacterized protein Cucumis sativus
TI:3659 None
 
A0A0K9NR11_ZOSMR
euHCVdb»
0.0
ZOSMA_6G01360 Putative WD-repeat protein Zostera marina
TI:29655 None
 
A0A0U9HJH8_KLENI
euHCVdb»
0.0
KFL_001130110 WD40 repeat protein Klebsormidium nitens
TI:105231 None
 
A0A1D5YIR8_WHEAT
EnsemblPlants»
0.0
LOC123111657 Uncharacterized protein Triticum aestivum
TI:4565 None
   
A0A1U7ZC15_NELNU
euHCVdb»
0.0
LOC104588549 THO complex subunit 3 Nelumbo nucifera
TI:4432 None
   
A0A251UAL6_HELAN
euHCVdb»
0.0
TEX1 Putative transducin/WD40 repeat-like superfamily
protein (Transcription factor WD40-like family)		 Helianthus annuus
TI:4232 None
 
A0A2C9VZQ5_MANES
euHCVdb»
0.0
MANES_04G054100v8 Uncharacterized protein Manihot esculenta
TI:3983 None
 
A0A2I4E3E0_JUGRE
euHCVdb»
0.0
LOC108985900 THO complex subunit 3 Juglans regia
TI:51240 None
   
A0A3Q7HIN8_SOLLC
EnsemblPlants»
0.0
LOC101265940 Uncharacterized protein Solanum lycopersicum
TI:4081 None
   
A0A5F8GTI7_MONDO
Ensembl»
0.0
Anaphase-promoting complex subunit
4-like WD40 domain-containing protein		 Monodelphis domestica
TI:13616 None
   
A0A7M7HCD5_STRPU
EnsemblMetazoa»
0.0
THO complex subunit 3 Strongylocentrotus purpuratus
TI:7668 None
   
A0A803T4W5_ANOCA
Ensembl»
0.0
Anaphase-promoting complex subunit
4-like WD40 domain-containing protein		 Anolis carolinensis
TI:28377 None
   
A0A8R1Z991_PRIPA
EnsemblMetazoa»
0.0
WBGene00304852 WD40 domain-containing protein Pristionchus pacificus
TI:54126 None
   
A0A9R1UDG2_LACSA
euHCVdb»
0.0
LSAT_V11C900497460 Anaphase-promoting complex subunit
4 WD40 domain-containing protein		 Lactuca sativa
TI:4236 None
 
A0A9R1VJI1_LACSA
euHCVdb»
0.0
LSAT_V11C500267330 Anaphase-promoting complex subunit
4 WD40 domain-containing protein		 Lactuca sativa
TI:4236 None
 
A0A9R1W4M9_LACSA
euHCVdb»
0.0
LSAT_V11C300153530 Anaphase-promoting complex subunit
4 WD40 domain-containing protein		 Lactuca sativa
TI:4236 None
 
A0A9R1WN10_LACSA
euHCVdb»
0.0
LSAT_V11C100048840 Anaphase-promoting complex subunit
4 WD40 domain-containing protein		 Lactuca sativa
TI:4236 None
 
A0A9R1XPN6_LACSA
euHCVdb»
0.0
LSAT_V11C300140890 Anaphase-promoting complex subunit
4 WD40 domain-containing protein		 Lactuca sativa
TI:4236 None
 
A0A9R1XQX7_LACSA
neXtProt»
0.0
LSAT_V11C300143750 Anaphase-promoting complex subunit
4 WD40 domain-containing protein		 Lactuca sativa
TI:4236 None
 
A0C5M6_PARTE
neXtProt»
0.0
GSPATT00035222001 Anaphase-promoting complex subunit
4 WD40 domain-containing protein		 Paramecium tetraurelia
TI:5888 None
 
A0DI78_PARTE
neXtProt»
0.0
GSPATT00017116001 Translation initiation factor
beta propellor-like domain-containing protein		 Paramecium tetraurelia
TI:5888 None
 
A0DPA6_PARTE
neXtProt»
0.0
GSPATT00019055001 Uncharacterized protein Paramecium tetraurelia
TI:5888 None
 
A2FU98_TRIV3
TubercuList»
0.0
TVAG_472710 Uncharacterized protein Trichomonas vaginalis
TI:5722 None
 
A5ADM7_VITVI
euHCVdb»
0.0
VIT_19s0015g01220 Uncharacterized protein Vitis vinifera
TI:29760 None
 
A7EN57_SCLS1
TubercuList»
0.0
SS1G_06756 Uncharacterized protein Sclerotinia sclerotiorum
TI:5180 None
 
A7SNF3_NEMVE
neXtProt»
0.0
NEMVEDRAFT_v1g172456 THO complex subunit 3 Nematostella vectensis
TI:45351 None
 
A8JHR3_CHLRE
neXtProt»
0.0
CHLRE_12g559850v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None
 
A8XFC9_CAEBR
WormBase»
0.0
thoc-3 Protein CBR-THOC-3.1 Caenorhabditis briggsae
TI:6238 None
 
A9P9W4_POPTR
euHCVdb»
0.0
POPTR_001G470900 Uncharacterized protein Populus trichocarpa
TI:3694 None
 
A9UT92_MONBE
euHCVdb»
0.0
MONBRDRAFT_23390 Anaphase-promoting complex subunit
4 WD40 domain-containing protein		 Monosiga brevicollis
TI:81824 None
 
AAC3_DICDI
dictyBase»
0.5
AAC3 WD repeat-containing protein AAC3
(AAC-rich mRNA clone AAC3 protein)		 Dictyostelium discoideum
TI:44689 None
 
B3RNZ7_TRIAD
CTD»
0.0
TRIADDRAFT_20906 Uncharacterized protein Trichoplax adhaerens
TI:10228 None
 
B6K6F5_SCHJY
TubercuList»
0.0
tho3 TRE Xcomplex subunit Tex1 Schizosaccharomyces japonicus
TI:4897 None
 
B8BTR0_THAPS
neXtProt»
0.0
THAPSDRAFT_2222 Anaphase-promoting complex subunit
4-like WD40 domain-containing protein		 Thalassiosira pseudonana
TI:35128 None
 
B9SUL6_RICCO
euHCVdb»
0.0
RCOM_0998840 WD-repeat protein, putative Ricinus communis
TI:3988 None
 
C3Y441_BRAFL
neXtProt»
0.0
LOC118414108 THO complex subunit 3-like Branchiostoma floridae
TI:7739 None
 
D6WIR9_TRICA
CTD»
0.0
AUGUSTUS-3.0.2_00095 F-box-like/WD repeat-containing protein ebi Tribolium castaneum
TI:7070 None
 
D8SHI3_SELML
neXtProt»
0.0
SELMODRAFT_179772 Uncharacterized protein Selaginella moellendorffii
TI:88036 None
 
D8T5S8_SELML
euHCVdb»
0.0
SELMODRAFT_185709 Uncharacterized protein Selaginella moellendorffii
TI:88036 None
 
E3KCI8_PUCGT
TubercuList»
0.0
PGTG_08185 Uncharacterized protein Puccinia graminis
TI:5297 None
 
E9H241_DAPPU
neXtProt»
0.0
DAPPUDRAFT_307424 Uncharacterized protein Daphnia pulex
TI:6669 None
 
F0ZU75_DICPU
TubercuList»
0.0
DICPUDRAFT_38307 Uncharacterized protein Dictyostelium purpureum
TI:5786 None
 
F1A2T3_DICPU
TubercuList»
0.0
DICPUDRAFT_51243 Uncharacterized protein Dictyostelium purpureum
TI:5786 None
 
F4P959_BATDJ
euHCVdb»
0.0
BATDEDRAFT_90779 Uncharacterized protein Batrachochytrium dendrobatidis
TI:109871 None
 
G7IY98_MEDTR
EnsemblPlants»
0.0
11438034 Putative transcription factor
WD40-like family (Transducin/WD-like repeat-protein)		 Medicago truncatula
TI:3880 None
 
H3GCK6_PHYRM
EnsemblProtists»
0.0
Uncharacterized protein Phytophthora ramorum
TI:164328 None
 
H8WGY8_CAEBR
WormBase»
0.0
Cbr-thoc-3.2 Protein CBR-THOC-3.2 Caenorhabditis briggsae
TI:6238 None
 
I1KYS6_SOYBN
EnsemblPlants»
0.0
LOC100782507 Uncharacterized protein Glycine max
TI:3847 None
 
I1N056_SOYBN
EnsemblPlants»
0.0
LOC100812126 Uncharacterized protein Glycine max
TI:3847 None
 
M1C059_SOLTU
EnsemblPlants»
0.0
LOC102597071 Transducin family protein Solanum tuberosum
TI:4113 None
   
M4CF63_BRACM
EnsemblPlants»
0.0
BRARA_J01048 Uncharacterized protein Brassica campestris
TI:3711 None
 
M5VXG7_PRUPE
neXtProt»
0.0
PRUPE_6G035000 Anaphase-promoting complex subunit
4-like WD40 domain-containing protein		 Prunus persica
TI:3760 None
 
M5W083_PRUPE
euHCVdb»
0.0
PRUPE_6G033200 Uncharacterized protein Prunus persica
TI:3760 None
 
Q4WQB0_ASPFU
TubercuList»
0.0
AFUA_4G12190 WD repeat-containing protein Aspergillus fumigatus
TI:746128 None
 
Q54XM5_DICDI
dictyBase»
0.5
DDB_G0278851 WD40 repeat-containing protein Dictyostelium discoideum
TI:44689 None
 
Q59X91_CANAL
CGD»
0.0
CAALFM_C500840WA orf19.8219 Uncharacterized protein Candida albicans
TI:5476 None
 
Q5B729_EMENI
TubercuList»
0.0
ANIA_03651 WD repeat-containing
protein (AFU_orthologue AFUA_4G12190)		 Emericella nidulans
TI:162425 None
 
Q5KJ91_CRYD1
TubercuList»
0.0
CND00190 Anaphase-promoting complex subunit
4 WD40 domain-containing protein		 Cryptococcus deneoformans
TI:40410 None
 
Q6C4P2_YARLI
TubercuList»
0.0
YALI0_E24827g YALI0E24827p Yarrowia lipolytica
TI:4952 None
 
Q752E2_EREGS
neXtProt»
0.0
AGOS_AFR634W AFR634Wp Eremothecium gossypii
TI:33169 None
 
Q7PTI6_ANOGA
EnsemblMetazoa»
0.0
1269478 AGAP003891-PA Anopheles gambiae
TI:7165 None
 
Q7SCY1_NEUCR
TubercuList»
0.0
NCU02753 WD repeat-containing protein Neurospora crassa
TI:5141 None
 
T1FNS0_HELRO
EnsemblMetazoa»
0.0
20210467 Uncharacterized protein Helobdella robusta
TI:6412 None
 
A0ABM3AH85_GOSHI
euHCVdb»
0.0
LOC107922831 THO complex subunit 3 Gossypium hirsutum
TI:3635 None
   
A0A067GEV5_CITSI
euHCVdb»
0.0
CISIN_1g0213192mg Uncharacterized protein Citrus sinensis
TI:2711 None
 
A0A2I2Y4U7_GORGO
Ensembl»
0.0
Anaphase-promoting complex subunit
4-like WD40 domain-containing protein		 Gorilla gorilla
TI:9593 None
 
A0A7U2I185_PHANO
TubercuList»
0.0
JI435_151150 Anaphase-promoting complex subunit
4 WD40 domain-containing protein		 Phaeosphaeria nodorum
TI:13684 None
 
A0A9R1WKB5_LACSA
euHCVdb»
0.0
LSAT_V11C100048830 Uncharacterized protein Lactuca sativa
TI:4236 None
 
A0ABI7ZR06_FELCA
Ensembl»
0.0
THOC3 THO complex 3 Felis catus
TI:9685 None
   
F1A669_DICPU
TubercuList»
0.0
DICPUDRAFT_85585 Uncharacterized protein Dictyostelium purpureum
TI:5786 None
 
F6ZML6_CIOIN
Ensembl»
0.0
Uncharacterized protein Ciona intestinalis
TI:7719 None