Collated Gene Ontology terms

Biological process: protein-disulfide reductase [NAD(P)H] activity(2008, 2017, 2018, 2025) peroxidase activity(2008, 2025) oxidoreductase activity(2025)

Molecular function: tumor necrosis factor-mediated signaling pathway2008, 2025 cellular oxidant detoxification2025 eye pigment biosynthetic process2006

Cellular component: cytosol2008, 2009, 2017, 2019, 2025 cytoplasm2018, 2025 nucleus2009, 2025 plastid2019 extracellular exosome2014

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 8/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
TXD17_MOUSE
Ensembl»
2.0
Txndc17 Thioredoxin domain-containing protein 17 (14 kDa thioredoxin-related
protein) (TRP14) (Protein 42-9-9) (Thioredoxin-like protein 5)		 Mus musculus
TI:10090 None
 
Q9VMQ9_DROME
FlyBase»
1.8
cl Thioredoxin domain-containing protein 17 Drosophila melanogaster
TI:7227 None
 
A0A1D5RCZ3_MACMU
Ensembl»
0.0
TXNDC17 Thioredoxin domain-containing protein
17 (Thioredoxin-like protein 5)		 Macaca mulatta
TI:9544 None
 
A0A286ZZM7_PIG
Ensembl»
0.0
TXNDC17 Thioredoxin domain-containing protein
17 (Thioredoxin-like protein 5)		 Sus scrofa
TI:9823 None
   
A0A9L0RY71_HORSE
Ensembl»
0.0
TXNDC17 Thioredoxin domain-containing protein
17 (Thioredoxin-like protein 5)		 Equus caballus
TI:9796 None
   
G3QKM5_GORGO
Ensembl»
0.0
TXNDC17 Thioredoxin domain-containing protein
17 (Thioredoxin-like protein 5)		 Gorilla gorilla
TI:9593 None
 
H2QC11_PANTR
Ensembl»
0.0
TXNDC17 Thioredoxin domain-containing protein
17 (Thioredoxin-like protein 5)		 Pan troglodytes
TI:9598 None
 
TXD17_HUMAN
Ensembl»
2.1
TXNDC17 Thioredoxin domain-containing protein 17 (14 kDa thioredoxin-related
protein) (TRP14) (Protein 42-9-9) (Thioredoxin-like protein 5)		 Homo sapiens
TI:9606 None
 
YOSC_SCHPO
PomBase»
0.5
SPBC21C3.12c Thioredoxin domain-containing protein C21C3.12c Schizosaccharomyces pombe
TI:4896 None
 
A0AAA9T355_BOVIN
Ensembl»
0.0
TXNDC17 Thioredoxin domain-containing protein
17 (Thioredoxin-like protein 5)		 Bos taurus
TI:9913 None
   
A0ABK0M2Q2_RAT
Ensembl»
1.5
Txndc17 Thioredoxin domain-containing protein 17 Rattus norvegicus
TI:10116 None
   
TCLOT_ARATH
TAIR»
0.5
At5g42850 Thioredoxin-like protein Clot
(Thioredoxin Clot) (AtClot)		 Arabidopsis thaliana
TI:3702 None
 
Q3KPS0_XENLA
Xenbase»
0.0
txndc17.S Thioredoxin domain-containing protein 17 Xenopus laevis
TI:8355 None
 
Q9U1K7_DROME
FlyBase»
1.0
EG:140G11.5 Thioredoxin domain-containing protein 17 Drosophila melanogaster
TI:7227 None
 
A0A139W9N0_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_31743 Thioredoxin domain-containing protein 17 Tribolium castaneum
TI:7070 None
 
A0A1S3ZPK1_TOBAC
euHCVdb»
0.0
LOC107789030 Thioredoxin-like protein Clot (Thioredoxin Clot) Nicotiana tabacum
TI:4097 None
   
A0A1S4H2T2_ANOGA
EnsemblMetazoa»
0.0
Thioredoxin domain-containing protein 17 Anopheles gambiae
TI:7165 None
 
A0A1U8HYN5_GOSHI
euHCVdb»
0.0
LOC107889220 Thioredoxin-like protein Clot (Thioredoxin Clot) Gossypium hirsutum
TI:3635 None
   
A0A1U8IT56_GOSHI
euHCVdb»
0.0
LOC107900008 Thioredoxin-like protein Clot (Thioredoxin Clot) Gossypium hirsutum
TI:3635 None
   
A0A3B3INS0_ORYLA
Ensembl»
0.0
TXNDC17 Thioredoxin domain-containing protein 17 Oryzias latipes
TI:8090 None
   
A0A6I8NVW7_ORNAN
Ensembl»
0.0
TXNDC17 Thioredoxin domain-containing protein
17 (Thioredoxin-like protein 5)		 Ornithorhynchus anatinus
TI:9258 None
   
A0A7M7RH54_STRPU
EnsemblMetazoa»
0.0
Thioredoxin domain-containing protein 17 Strongylocentrotus purpuratus
TI:7668 None
   
A0A8J0R102_XENTR
Xenbase»
0.0
txndc17 Thioredoxin domain-containing protein 17 Xenopus tropicalis
TI:8364 None
   
A0A9J7LXM2_BRAFL
euHCVdb»
0.0
LOC118426028 Thioredoxin domain-containing protein 17 Branchiostoma floridae
TI:7739 None
   
A0A9R0HRA7_SPIOL
euHCVdb»
0.0
LOC110774941 Thioredoxin-like protein Clot (Thioredoxin Clot) Spinacia oleracea
TI:3562 None
   
A7S2D0_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g165587 Thioredoxin domain-containing protein 17 Nematostella vectensis
TI:45351 None
 
E9HMQ5_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_302246 Thioredoxin domain-containing protein 17 Daphnia pulex
TI:6669 None
 
F7FLG4_ORNAN
Ensembl»
0.0
LOC100080754 Thioredoxin domain-containing protein
17 (Thioredoxin-like protein 5)		 Ornithorhynchus anatinus
TI:9258 None
   
H2XSJ3_CIOIN
Ensembl»
0.0
LOC100175262 Thioredoxin domain-containing protein 17 Ciona intestinalis
TI:7719 None
   
Q7QBG9_ANOGA
EnsemblMetazoa»
0.0
GRX2 Thioredoxin domain-containing protein 17 Anopheles gambiae
TI:7165 None
 
Q9BL27_CAEEL
WormBase»
0.5
txdc-17 Thioredoxin domain-containing protein 17 Caenorhabditis elegans
TI:6239 None
 
TXD17_DANRE
ZFIN»
0.5
txndc17 Thioredoxin domain-containing protein
17 (Thioredoxin-like protein 5)		 Danio rerio
TI:7955 None
 
W5MGS6_LEPOC
Ensembl»
0.0
Thioredoxin domain-containing protein 17 Lepisosteus oculatus
TI:7918 None
 
A0A022QRI9_ERYGU
euHCVdb»
0.0
MIMGU_mgv1a016170mg Thioredoxin-like protein Clot (Thioredoxin Clot) Erythranthe guttata
TI:4155 None
 
A0A061DVN1_THECC
euHCVdb»
0.0
TCM_005930 Thioredoxin-like protein Clot (Thioredoxin Clot) Theobroma cacao
TI:3641 None
 
A0A067GV33_CITSI
euHCVdb»
0.0
CISIN_1g032841mg Thioredoxin-like protein Clot (Thioredoxin Clot) Citrus sinensis
TI:2711 None
 
A0A078GBC7_BRANA
euHCVdb»
0.0
BnaA06g37040D Thioredoxin-like protein Clot (Thioredoxin Clot) Brassica napus
TI:3708 None
 
A0A0A0LEX6_CUCSA
euHCVdb»
0.0
Csa_3G701560 Thioredoxin-like protein Clot (Thioredoxin Clot) Cucumis sativus
TI:3659 None
 
A0A0K9PJ26_ZOSMR
euHCVdb»
0.0
ZOSMA_246G00270 Thioredoxin-like protein Clot (Thioredoxin Clot) Zostera marina
TI:29655 None
 
A0A0S2M6B1_CRYD1
TubercuList»
0.0
CNL05845 Thioredoxin domain-containing protein Cryptococcus deneoformans
TI:40410 None
 
A0A1U7ZUU9_NELNU
euHCVdb»
0.0
LOC104597520 Thioredoxin-like protein Clot (Thioredoxin Clot) Nelumbo nucifera
TI:4432 None
   
A0A1U8ASN9_NELNU
euHCVdb»
0.0
LOC104603489 Thioredoxin-like protein Clot (Thioredoxin Clot) Nelumbo nucifera
TI:4432 None
   
A0A1U8E4S2_CAPAN
euHCVdb»
0.0
T459_33072 Thioredoxin-like protein Clot (Thioredoxin Clot) Capsicum annuum
TI:4072 None
 
A0A1Y1HZA2_KLENI
euHCVdb»
0.0
KFL_000730250 Thioredoxin domain-containing protein Klebsormidium nitens
TI:105231 None
 
A0A251VPX2_HELAN
euHCVdb»
0.0
HannXRQ_Chr01g0018511 HanXRQr2_Chr01g0026931 Thioredoxin-like protein Clot (Thioredoxin Clot) Helianthus annuus
TI:4232 None
 
A0A2C9V6J4_MANES
euHCVdb»
0.0
MANES_10G148300v8 Thioredoxin-like protein Clot (Thioredoxin Clot) Manihot esculenta
TI:3983 None
 
A0A2G2XZE0_CAPAN
euHCVdb»
0.0
T459_33244 Thioredoxin-like protein Clot (Thioredoxin Clot) Capsicum annuum
TI:4072 None
 
A0A2G2Z2Z9_CAPAN
euHCVdb»
0.0
T459_19922 Thioredoxin-like protein Clot Capsicum annuum
TI:4072 None
 
A0A2G2ZHV2_CAPAN
euHCVdb»
0.0
T459_14585 Thioredoxin domain-containing protein Capsicum annuum
TI:4072 None
 
A0A2I4G2W9_JUGRE
euHCVdb»
0.0
LOC109004233 Thioredoxin-like protein Clot (Thioredoxin Clot) Juglans regia
TI:51240 None
   
A0A2K3D696_CHLRE
neXtProt»
0.0
CHLRE_12g549500v5 Thioredoxin domain-containing protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A2K3DIN0_CHLRE
euHCVdb»
0.0
CHLRE_07g315100v5 Thioredoxin domain-containing protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A2R6X9Q7_MARPO
euHCVdb»
0.0
MARPO_0028s0130 Thioredoxin domain-containing protein Marchantia polymorpha
TI:3197 None
 
A0A3B6RH73_WHEAT
EnsemblPlants»
0.0
LOC123150603 Thioredoxin-like protein Clot (Thioredoxin Clot) Triticum aestivum
TI:4565 None
   
A0A3B6SH88_WHEAT
EnsemblPlants»
0.0
LOC123155721 Thioredoxin-like protein Clot (Thioredoxin Clot) Triticum aestivum
TI:4565 None
   
A0A3B6TP00_WHEAT
EnsemblPlants»
0.0
Thioredoxin-like protein Clot (Thioredoxin Clot) Triticum aestivum
TI:4565 None
   
A0A3Q7IET1_SOLLC
EnsemblPlants»
0.0
LOC101259890 Thioredoxin-like protein Clot (Thioredoxin Clot) Solanum lycopersicum
TI:4081 None
   
A0A7I4BSN1_PHYPA
EnsemblPlants»
0.0
LOC112292074 Thioredoxin domain-containing protein Physcomitrium patens
TI:3218 None
 
A0A804IJU0_MUSAM
EnsemblPlants»
0.0
GSMUA_106810.1 Thioredoxin-like protein Clot (Thioredoxin Clot) Musa acuminata
TI:4641 None
 
A0A8R1V360_PRIPA
EnsemblMetazoa»
0.0
WBGene00304948 Thioredoxin domain-containing protein 17
(Thioredoxin Clot) (Thioredoxin-like protein Clot)		 Pristionchus pacificus
TI:54126 None
   
A0A9R1UR63_LACSA
euHCVdb»
0.0
LSAT_V11C800392260 Thioredoxin-like protein Clot (Thioredoxin Clot) Lactuca sativa
TI:4236 None
 
A0CAU3_PARTE
neXtProt»
0.0
GSPATT00036691001 Thioredoxin domain-containing protein Paramecium tetraurelia
TI:5888 None
 
A0E6U1_PARTE
euHCVdb»
0.0
GSPATT00023736001 Thioredoxin domain-containing protein Paramecium tetraurelia
TI:5888 None
 
A7EXP4_SCLS1
TubercuList»
0.0
SS1G_10109 Thioredoxin domain-containing protein Sclerotinia sclerotiorum
TI:5180 None
 
A8WMS2_CAEBR
WormBase»
0.0
CBG00487 CBG_00487 Thioredoxin domain-containing protein 17 Caenorhabditis briggsae
TI:6238 None
 
A9PBT3_POPTR
euHCVdb»
0.0
POPTR_001G225500 Thioredoxin-like protein Clot (Thioredoxin Clot) Populus trichocarpa
TI:3694 None
 
B0G106_DICDI
dictyBase»
0.5
DDB_G0272418 Thioredoxin fold domain-containing protein Dictyostelium discoideum
TI:44689 None
 
B3SAM7_TRIAD
CTD»
0.0
TRIADDRAFT_61314 Thioredoxin domain-containing protein 17 Trichoplax adhaerens
TI:10228 None
 
B8A1M2_MAIZE
EnsemblPlants»
0.0
LOC100280051 Thioredoxin-like protein Clot (Thioredoxin Clot) Zea mays
TI:4577 None
 
B9RHH6_RICCO
euHCVdb»
0.0
RCOM_1526930 Thioredoxin-like protein Clot (Thioredoxin Clot) Ricinus communis
TI:3988 None
 
C5Z1N7_SORBI
euHCVdb»
0.0
SORBI_3010G132100 Thioredoxin-like protein Clot (Thioredoxin Clot) Sorghum bicolor
TI:4558 None
 
C6SWX2_SOYBN
EnsemblPlants»
0.0
LOC100785157 Thioredoxin-like protein Clot (Thioredoxin Clot) Glycine max
TI:3847 None
 
D7T2W1_VITVI
euHCVdb»
0.0
VvCHDp000735 Thioredoxin-like protein Clot (Thioredoxin Clot) Vitis vinifera
TI:29760 None
 
D8T659_SELML
euHCVdb»
0.0
SELMODRAFT_132775 Thioredoxin domain-containing protein Selaginella moellendorffii
TI:88036 None
 
D8T7U3_SELML
neXtProt»
0.0
SELMODRAFT_134020 Thioredoxin domain-containing protein Selaginella moellendorffii
TI:88036 None
 
E3K7L1_PUCGT
TubercuList»
0.0
PGTG_06267 Thioredoxin domain-containing protein Puccinia graminis
TI:5297 None
 
F2DHB9_HORVV
EnsemblPlants»
0.0
LOC123412947 Thioredoxin-like protein Clot (Thioredoxin Clot) Hordeum vulgare
TI:4513 None
 
F4NYK8_BATDJ
euHCVdb»
0.0
BATDEDRAFT_86770 Thioredoxin domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
G7J1S6_MEDTR
EnsemblPlants»
0.0
11419588 Thioredoxin-like protein Clot (Thioredoxin Clot) Medicago truncatula
TI:3880 None
 
H3GSJ0_PHYRM
EnsemblProtists»
0.0
Thioredoxin domain-containing protein Phytophthora ramorum
TI:164328 None
 
H3GSJ1_PHYRM
EnsemblProtists»
0.0
Thioredoxin domain-containing protein Phytophthora ramorum
TI:164328 None
 
H3GSJ2_PHYRM
EnsemblProtists»
0.0
Thioredoxin domain-containing protein Phytophthora ramorum
TI:164328 None
 
H3GSJ7_PHYRM
EnsemblProtists»
0.0
Thioredoxin domain-containing protein Phytophthora ramorum
TI:164328 None
 
I1IMT0_BRADI
EnsemblPlants»
0.0
LOC100822680 Thioredoxin-like protein Clot (Thioredoxin Clot) Brachypodium distachyon
TI:15368 None
 
I1KTJ7_SOYBN
EnsemblPlants»
0.0
LOC100810656 Thioredoxin-like protein Clot (Thioredoxin Clot) Glycine max
TI:3847 None
 
K7L6V9_SOYBN
EnsemblPlants»
0.0
GLYMA_08G152300 Thioredoxin domain-containing protein Glycine max
TI:3847 None
 
M1CHX0_SOLTU
EnsemblPlants»
0.0
LOC102606005 Thioredoxin-like protein Clot (Thioredoxin Clot) Solanum tuberosum
TI:4113 None
   
M4EXV6_BRACM
EnsemblPlants»
0.0
Thioredoxin-like protein Clot (Thioredoxin Clot) Brassica campestris
TI:3711 None
   
M5XL63_PRUPE
euHCVdb»
0.0
PRUPE_2G007200 Thioredoxin-like protein Clot (Thioredoxin Clot) Prunus persica
TI:3760 None
 
OCLOT_ORYSJ
EnsemblPlants»
0.0
Os06g0320000 LOC_Os06g21550 Thioredoxin-like protein Clot
(Thioredoxin Clot) (OsClot)		 Oryza sativa
TI:4530 None
 
Q5ASV0_EMENI
TubercuList»
0.0
ANIA_08630 Thioredoxin domain-containing protein Emericella nidulans
TI:162425 None
 
Q5K8C9_CRYD1
TubercuList»
0.0
CNL06140 Expressed protein Cryptococcus deneoformans
TI:40410 None
 
T1FNU0_HELRO
EnsemblMetazoa»
0.0
20210487 Thioredoxin domain-containing protein 17 Helobdella robusta
TI:6412 None
 
W1PVC3_AMBTC
euHCVdb»
0.0
AMTR_s00022p00212550 Thioredoxin-like protein Clot (Thioredoxin Clot) Amborella trichopoda
TI:13333 None
 
A0A8I3N199_CANLF
Ensembl»
0.0
TXNDC17 Thioredoxin domain-containing protein
17 (Thioredoxin-like protein 5)		 Canis lupus
TI:9612 None
   
A0A7U2EZR9_PHANO
TubercuList»
0.0
JI435_159040 Thioredoxin domain-containing protein Phaeosphaeria nodorum
TI:13684 None
 
A0A7U2HWA9_PHANO
TubercuList»
0.0
JI435_078960 Thioredoxin domain-containing protein Phaeosphaeria nodorum
TI:13684 None
 
A0A8V1ABX0_CHICK
Ensembl»
0.0
TXNDC17 Thioredoxin domain containing 17 Gallus gallus
TI:9031 None
   
A0ABI8ADY3_FELCA
Ensembl»
0.0
TXNDC17 Thioredoxin domain-containing protein 17 Felis catus
TI:9685 None
   
B6JVS3_SCHJY
TubercuList»
0.0
SJAG_00489 DUF953 family protein Schizosaccharomyces japonicus
TI:4897 None
 
F1A543_DICPU
TubercuList»
0.0
DICPUDRAFT_43939 Thioredoxin domain-containing protein Dictyostelium purpureum
TI:5786 None