Collated Gene Ontology terms

Biological process: membrane insertase activity(2020, 2022, 2023)

Molecular function: protein insertion into ER membrane by stop-transfer membrane-anchor sequence2020, 2023 tail-anchored membrane protein insertion into ER membrane2020, 2022, 2023

Cellular component: EMC complex2012, 2020, 2023 cytoplasm2012, 2023 endoplasmic reticulum2016, 2017, 2021, 2023 endoplasmic reticulum membrane2020, 2023 membrane2014, 2023 Golgi apparatus2023 striated muscle dense body2012 plastid2019 mitochondrion2007 endomembrane system2014

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 5/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 0 2 4 6 8 10 Knownness

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
EMC8_HUMAN
Ensembl»
3.2
EMC8 ER membrane protein complex subunit
8 (Neighbor of COX4) (Protein FAM158B)		 Homo sapiens
TI:9606 None
 
H2Q819_PANTR
Ensembl»
0.0
EMC9 ER membrane protein complex subunit 9
(Family with sequence similarity 158, member A)		 Pan troglodytes
TI:9598 None
 
H2QBN4_PANTR
Ensembl»
0.0
EMC8 COX4 neighbor (ER membrane
protein complex subunit 8)		 Pan troglodytes
TI:9598 None
 
A0A078GU45_BRANA
EnsemblPlants»
0.0
BnaC09g32480D (rape) hypothetical protein
(BnaA10g10020D protein) (BnaC09g32480D protein)		 Brassica napus
TI:3708 None
 
EMC89_ARATH
TAIR»
0.0
EMB2731 ER membrane protein complex subunit
8/9 homolog (Protein EMBRYO DEFECTIVE 2731)		 Arabidopsis thaliana
TI:3702 None
 
EMC9_HUMAN
Ensembl»
3.2
EMC9 ER membrane protein complex
subunit 9 (Protein FAM158A)		 Homo sapiens
TI:9606 None
 
G3RLC5_GORGO
Ensembl»
0.0
EMC8 ER membrane protein complex subunit 8 Gorilla gorilla
TI:9593 None
 
G7KEJ5_MEDTR
EnsemblPlants»
0.0
11433699 ER membrane protein complex subunit-like protein
(Putative ER membrane protein complex subunit 8/9)		 Medicago truncatula
TI:3880 None
 
Q7XWV6_ORYSJ
EnsemblPlants»
0.0
Os04g0270200 Os04g0270200 protein (cDNA clone:001-040-F11, full insert
sequence) (cDNA clone:J013110N19, full insert sequence)		 Oryza sativa
TI:4530 None
 
Q8L439_CHLRE
EnsemblPlants»
0.0
TLA1 Chlorophyll antenna size regulatory protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A078FIN8_BRANA
EnsemblPlants»
0.0
BnaC03g13940D (rape) hypothetical
protein (BnaC03g13940D protein)		 Brassica napus
TI:3708 None
 
A0A078HEI0_BRANA
EnsemblPlants»
0.0
BnaA03g11160D (rape) hypothetical
protein (BnaA03g11160D protein)		 Brassica napus
TI:3708 None
 
A0A078JEU1_BRANA
EnsemblPlants»
0.0
BnaA02g35420D (rape) hypothetical
protein (BnaA02g35420D protein)		 Brassica napus
TI:3708 None
 
A0A1D5V0Z3_WHEAT
EnsemblPlants»
0.0
CAMPLR22A2D_LOCUS633 CFC21_027740 Genome assembly, chromosome: II Triticum aestivum
TI:4565 None
 
A0A251TA53_HELAN
EnsemblPlants»
0.0
EMC9 ER membrane protein complex subunit 8/9
(Putative ER membrane protein complex subunit 9)		 Helianthus annuus
TI:4232 None
 
A0A251V287_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr04g0114541 HanXRQr2_Chr06g0270901 ER membrane protein complex subunit 8/9 Helianthus annuus
TI:4232 None
 
B6T5Q6_MAIZE
EnsemblPlants»
0.0
100276147 ER membrane protein
complex subunit 8/9-like protein		 Zea mays
TI:4577 None
 
B7P0N7_IXOSC
EnsemblMetazoa»
0.0
8023129 COX4 neighbor protein, putative Ixodes scapularis
TI:6945 None
 
C6SYG0_SOYBN
EnsemblPlants»
0.0
100306212 MPN domain-containing protein Glycine max
TI:3847 None
 
C6T3E5_SOYBN
EnsemblPlants»
0.0
100527135 MPN domain-containing protein Glycine max
TI:3847 None
 
EMC8_MOUSE
Ensembl»
3.0
Emc8 ER membrane protein complex
subunit 8 (Neighbor of COX4)		 Mus musculus
TI:10090 None
 
EMC9_MOUSE
Ensembl»
3.0
Emc9 ER membrane protein complex
subunit 9 (Protein FAM158A)		 Mus musculus
TI:10090 None
 
K3YA14_SETIT
EnsemblPlants»
0.0
101764250 MPN domain-containing protein Setaria italica
TI:4555 None
 
Q580G6_TRYB2
VEuPathDB»
0.0
Tb08.29O9.280 MPN domain-containing protein Trypanosoma brucei
TI:5691 None
 
Q6P4M9_XENTR
Xenbase»
0.0
emc8 COX4 neighbor (ER membrane protein
complex subunit 8) (Novel protein)		 Xenopus tropicalis
TI:8364 None
 
Q7ZUY2_DANRE
ZFIN»
0.0
cox4nb Cox4 neighbor (ER membrane
protein complex subunit 8)		 Danio rerio
TI:7955 None
 
Q8AWD7_DANRE
ZFIN»
0.0
zgc:55317 ER membrane protein
complex subunit 9 (Zgc:55317)		 Danio rerio
TI:7955 None
 
T1ELZ1_HELRO
EnsemblMetazoa»
0.0
20197591 MPN domain-containing protein Helobdella robusta
TI:6412 None
 
A0A022R4F1_ERYGU
Ensembl»
0.0
MIMGU_mgv1a014067mg MPN domain-containing protein Erythranthe guttata
TI:4155 None
 
A0A059BRV6_EUCGR
EnsemblPlants»
0.0
EUGRSUZ_F02035 MPN domain-containing protein Eucalyptus grandis
TI:71139 None
 
A0A061F4Y0_THECC
EnsemblPlants»
0.0
TCM_030596 UPF0172 protein Theobroma cacao
TI:3641 None
 
A0A067EVQ6_CITSI
Ensembl»
0.0
CISIN_1g028839mg MPN domain-containing protein Citrus sinensis
TI:2711 None
 
A0A0A0KYR9_CUCSA
EnsemblPlants»
0.0
Csa_4G419600 MPN domain-containing protein Cucumis sativus
TI:3659 None
 
A0A0D1CST8_USTMA
EnsemblFungi»
0.0
UMAG_11470 MPN domain-containing protein Ustilago maydis
TI:5270 None
 
A0A0K9PMK0_ZOSMR
EnsemblPlants»
0.0
ZOSMA_1G02770 Putative Neighbor of COX4 Zostera marina
TI:29655 None
 
A0A0S2M5R0_CRYNJ
EnsemblFungi»
0.0
CNG02035 MPN domain-containing protein Cryptococcus neoformans
TI:5207 None
 
A0A1B6QID0_SORBI
EnsemblPlants»
0.0
SORBI_3001G105100 MPN domain-containing protein Sorghum bicolor
TI:4558 None
 
A0A1P8BFG8_ARATH
TAIR»
0.0
At5g51620 Uncharacterized protein family (UPF0172) Arabidopsis thaliana
TI:3702 None
 
A0A1U8HGZ8_CAPAN
EnsemblPlants»
0.0
T459_18844 ER membrane protein
complex subunit 8/9-like protein		 Capsicum annuum
TI:4072 None
 
A0A1Y1IGU9_KLENI
EnsemblPlants»
0.0
KFL_003480120 MPN domain-containing protein Klebsormidium nitens
TI:105231 None
 
A0A2A6BGY9_PRIPA
EnsemblMetazoa»
0.0
WBGene00116297 MPN domain-containing protein Pristionchus pacificus
TI:54126 None
 
A0A2C9UED2_MANES
EnsemblPlants»
0.0
MANES_15G058100 MPN domain-containing protein Manihot esculenta
TI:3983 None
 
A0A2I2UJ90_FELCA
Ensembl»
0.0
EMC9 ER membrane protein complex subunit 9 Felis catus
TI:9685 None
 
A0A2I4F1U0_JUGRE
EnsemblPlants»
0.0
LOC108994741 ER membrane protein complex subunit 8/9 homolog Juglans regia
TI:51240 None
 
A0A2K1J4E0_PHYPA
EnsemblPlants»
0.0
PHYPA_022242 MPN domain-containing protein Physcomitrium patens
TI:3218 None
 
A0A2K1JIJ2_PHYPA
EnsemblPlants»
0.0
PHYPA_018777 MPN domain-containing protein Physcomitrium patens
TI:3218 None
 
A0A2K2C9P5_POPTR
EnsemblPlants»
0.0
POPTR_001G370000 MPN domain-containing protein Populus trichocarpa
TI:3694 None
 
A0A2R6WAL4_MARPO
EnsemblPlants»
0.0
MARPO_0118s0025 MPN domain-containing protein Marchantia polymorpha
TI:3197 None
 
A0A337SUW7_FELCA
Ensembl»
0.0
EMC8 ER membrane protein complex subunit 8 Felis catus
TI:9685 None
 
A0A3B6AQU5_WHEAT
EnsemblPlants»
0.0
CFC21_015125 MPN domain-containing protein Triticum aestivum
TI:4565 None
 
A0A3B6C1S1_WHEAT
EnsemblPlants»
0.0
CFC21_021421 MPN domain-containing protein Triticum aestivum
TI:4565 None
 
A0A804HPV9_MUSAM
EnsemblPlants»
0.0
GSMUA_287370.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0CVM0_PARTE
EnsemblProtists»
0.0
GSPATT00011005001 Chromosome undetermined scaffold_29,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A0D917_PARTE
EnsemblProtists»
0.0
GSPATT00014480001 Chromosome undetermined scaffold_41,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A7RMN9_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g160601 MPN domain-containing protein Nematostella vectensis
TI:45351 None
 
A8WS69_CAEBR
WormBase»
0.0
CBG02246 CBG_02246 Protein CBG02246 Caenorhabditis briggsae
TI:6238 None
 
A9UQH6_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_22408 MPN domain-containing protein Monosiga brevicollis
TI:81824 None
 
B3S6U6_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_29978 MPN domain-containing protein Trichoplax adhaerens
TI:10228 None
 
B8C265_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_5178 MPN domain-containing protein Thalassiosira pseudonana
TI:35128 None
 
B9GFZ6_POPTR
EnsemblPlants»
0.0
POPTR_001G370200 MPN domain-containing protein Populus trichocarpa
TI:3694 None
 
B9S9X3_RICCO
EnsemblBacteria»
0.0
RCOM_0523270 Neighbor of COX4, putative Ricinus communis
TI:3988 None
 
C3ZBN0_BRAFL
CTD»
0.0
LOC118417765 ER membrane protein complex subunit 8-like Branchiostoma floridae
TI:7739 None
 
C5YDD7_SORBI
EnsemblPlants»
0.0
SORBI_3006G034800 MPN domain-containing protein Sorghum bicolor
TI:4558 None
 
D6WHD0_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_02922 ER membrane protein complex
subunit 8/9 homolog-like Protein		 Tribolium castaneum
TI:7070 None
 
D7UAL1_VITVI
EnsemblPlants»
0.0
VIT_19s0015g00910 MPN domain-containing protein Vitis vinifera
TI:29760 None
 
D8QNN0_SELML
EnsemblPlants»
0.0
SELMODRAFT_73953 MPN domain-containing protein Selaginella moellendorffii
TI:88036 None
 
D8RDW5_SELML
EnsemblPlants»
0.0
SELMODRAFT_91476 MPN domain-containing protein Selaginella moellendorffii
TI:88036 None
 
E3KPT4_PUCGT
EnsemblFungi»
0.0
PGTG_12275 MPN domain-containing protein Puccinia graminis
TI:5297 None
 
E9H1Y4_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_307352 MPN domain-containing protein Daphnia pulex
TI:6669 None
 
EMC89_DICDI
dictyBase»
0.0
DDB_G0268048 ER membrane protein complex subunit 8/9 homolog Dictyostelium discoideum
TI:44689 None
 
EMC89_DROME
FlyBase»
2.1
EMC8-9 ER membrane protein complex subunit 8/9 homolog Drosophila melanogaster
TI:7227 None
 
EMC8_BOVIN
CTD»
0.0
EMC8 ER membrane protein complex
subunit 8 (Neighbor of COX4)		 Bos taurus
TI:9913 None
 
EMC8_RAT
RGD»
3.0
Emc8 ER membrane protein complex
subunit 8 (Neighbor of COX4)		 Rattus norvegicus
TI:10116 None
 
EMC9_RAT
RGD»
3.0
Emc9 ER membrane protein complex
subunit 9 (Protein FAM158A)		 Rattus norvegicus
TI:10116 None
 
F0ZM58_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_79295 MPN domain-containing protein Dictyostelium purpureum
TI:5786 None
 
F1SGM2_PIG
Ensembl»
0.0
EMC9 ER membrane protein complex subunit 9 (ER
membrane protein complex subunit 9 isoform X1)		 Sus scrofa
TI:9823 None
 
F4P6T5_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_90046 MPN domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
H2XJW9_CIOIN
Ensembl»
0.0
MPN domain-containing protein Ciona intestinalis
TI:7719 None
 
I1IWN9_BRADI
EnsemblPlants»
0.0
100841998 MPN domain-containing protein Brachypodium distachyon
TI:15368 None
 
M5W166_PRUPE
EnsemblPlants»
0.0
PRUPE_6G026500 Uncharacterized protein Prunus persica
TI:3760 None
 
Q4QIR5_LEIMA
EnsemblProtists»
0.0
LMJF_07_0290 MPN domain-containing protein Leishmania major
TI:5664 None
 
Q5TPN5_ANOGA
EnsemblMetazoa»
0.0
3292446 AGAP010320-PA Anopheles gambiae
TI:7165 None
 
Q8IHW7_PLAF7
EnsemblProtists»
0.0
PF3D7_1139900 ER membrane protein complex subunit 8, putative Plasmodium falciparum
TI:5833 None
 
Q93568_CAEEL
WormBase»
0.0
CELE_F25H2.4 F25H2.4 MPN domain-containing protein Caenorhabditis elegans
TI:6239 None
 
W1NI66_AMBTC
EnsemblPlants»
0.0
AMTR_s00009p00262730 MPN domain-containing protein Amborella trichopoda
TI:13333 None
 
W5LY47_LEPOC
Ensembl»
0.0
ER membrane protein complex subunit 8 Lepisosteus oculatus
TI:7918 None
 
A0A1D5Q4Q1_MACMU
Ensembl»
0.0
EMC9 ER membrane protein complex subunit 9 Macaca mulatta
TI:9544 None
   
A0A1D5R636_MACMU
Ensembl»
0.0
EMC8 ER membrane protein complex subunit 8 Macaca mulatta
TI:9544 None
   
A0A1S3XGG6_TOBAC
EnsemblFungi»
0.0
LOC107764945 ER membrane protein complex subunit 8/9 homolog Nicotiana tabacum
TI:4097 None
   
A0A1S3YGA2_TOBAC
EnsemblFungi»
0.0
LOC107775949 ER membrane protein complex subunit 8/9 homolog Nicotiana tabacum
TI:4097 None
   
A0A1S4ABW8_TOBAC
EnsemblFungi»
0.0
LOC107795914 ER membrane protein complex subunit 8/9 homolog Nicotiana tabacum
TI:4097 None
   
A0A1S4BDS5_TOBAC
EnsemblFungi»
0.0
LOC107807154 ER membrane protein complex subunit 8/9 homolog Nicotiana tabacum
TI:4097 None
   
A0A1U7ZD14_NELNU
EnsemblBacteria»
0.0
LOC104588827 ER membrane protein complex subunit 8/9 homolog Nelumbo nucifera
TI:4432 None
   
A0A1U8BIH7_NELNU
EnsemblBacteria»
0.0
LOC104611464 ER membrane protein complex subunit 8/9 homolog Nelumbo nucifera
TI:4432 None
   
A0A1U8L0R2_GOSHI
Ensembl»
0.0
LOC107922609 ER membrane protein complex subunit 8/9 homolog Gossypium hirsutum
TI:3635 None
   
A0A1U8LYY8_GOSHI
Ensembl»
0.0
LOC107931188 ER membrane protein complex subunit 8/9 homolog Gossypium hirsutum
TI:3635 None
   
A0A2I2YZI0_GORGO
Ensembl»
0.0
ER membrane protein complex subunit 9 Gorilla gorilla
TI:9593 None
   
A0A2I4E202_JUGRE
EnsemblPlants»
0.0
LOC108985544 ER membrane protein complex subunit 8/9 homolog Juglans regia
TI:51240 None
   
A0A3B3IBB2_ORYLA
Ensembl»
0.0
ER membrane protein complex subunit 9 Oryzias latipes
TI:8090 None
   
A0A3B3IGA6_ORYLA
Ensembl»
0.0
emc8 ER membrane protein complex subunit 8 Oryzias latipes
TI:8090 None
   
A0A3Q2HTF6_HORSE
Ensembl»
0.0
EMC9 ER membrane protein complex subunit 9 Equus caballus
TI:9796 None
   
A0A3Q7H4R2_SOLLC
EnsemblPlants»
0.0
101268196 MPN domain-containing protein Solanum lycopersicum
TI:4081 None
   
A0A5F5PQN3_HORSE
Ensembl»
0.0
EMC8 ER membrane protein complex subunit 8 Equus caballus
TI:9796 None
   
A0A5F8HG77_MONDO
Ensembl»
0.0
EMC9 ER membrane protein complex subunit 9 Monodelphis domestica
TI:13616 None
   
A0A5G2QJM6_PIG
Ensembl»
0.0
EMC8 MPN domain-containing protein Sus scrofa
TI:9823 None
   
A0A6I8NEX8_ORNAN
Ensembl»
0.0
EMC9 ER membrane protein complex subunit 9 Ornithorhynchus anatinus
TI:9258 None
   
A0A6I8PEL9_ORNAN
Ensembl»
0.0
EMC8 ER membrane protein complex subunit 8 Ornithorhynchus anatinus
TI:9258 None
   
A0A7M7N6P8_STRPU
EnsemblMetazoa»
0.0
MPN domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A8I3MPT8_CANLF
Ensembl»
0.0
EMC8 MPN domain-containing protein Canis lupus
TI:9612 None
   
A0A8I3N960_CANLF
Ensembl»
0.0
EMC9 ER membrane protein complex subunit 9 Canis lupus
TI:9612 None
   
A0A8I6X1I3_HORVV
EnsemblPlants»
0.0
MPN domain-containing protein Hordeum vulgare
TI:4513 None
   
E1BF12_BOVIN
Ensembl»
0.0
EMC9 ER membrane protein complex subunit 9 Bos taurus
TI:9913 None
   
F1N5N2_BOVIN
Ensembl»
0.0
EMC8 ER membrane protein complex subunit 8 Bos taurus
TI:9913 None
   
F1N8E6_CHICK
Ensembl»
0.0
EMC8 ER membrane protein complex subunit 8 Gallus gallus
TI:9031 None
   
F6QIS0_MONDO
Ensembl»
0.0
EMC8 ER membrane protein complex subunit 8 Monodelphis domestica
TI:13616 None
   
F6SMK1_XENTR
Xenbase»
0.0
emc9 ER membrane protein complex subunit 9 Xenopus tropicalis
TI:8364 None
   
F7FT91_MONDO
Ensembl»
0.0
MPN domain-containing protein Monodelphis domestica
TI:13616 None
   
H2MDQ3_ORYLA
Ensembl»
0.0
ER membrane protein complex subunit 9 Oryzias latipes
TI:8090 None
   
H9GAA6_ANOCA
Ensembl»
0.0
EMC8 ER membrane protein complex subunit 8 Anolis carolinensis
TI:28377 None
   
M1AGM8_SOLTU
EnsemblPlants»
0.0
102580872 Neighbor of COX4 Solanum tuberosum
TI:4113 None
   
M1C8P1_SOLTU
EnsemblPlants»
0.0
102599477 Neighbor of COX4 Solanum tuberosum
TI:4113 None
   
W5LYZ5_LEPOC
Ensembl»
0.0
ER membrane protein complex subunit 9 Lepisosteus oculatus
TI:7918 None