Collated Gene Ontology terms

Biological process: membrane insertase activity(2020, 2022, 2025)

Molecular function: protein insertion into ER membrane by stop-transfer membrane-anchor sequence2020, 2024, 2025 tail-anchored membrane protein insertion into ER membrane2020, 2022, 2024, 2025

Cellular component: EMC complex2012, 2020, 2025 endoplasmic reticulum membrane2024, 2025 cytoplasm2012, 2025 endoplasmic reticulum2016, 2017, 2021, 2024, 2025 striated muscle dense body2012 plastid2019 peroxisome2017 nucleus2018 nuclear envelope2025 mitochondrion2007
membrane2014 endomembrane system2014 Golgi apparatus2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 4/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 39/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
EMC8_MOUSE
Ensembl»
4.5
Emc8 ER membrane protein complex
subunit 8 (Neighbor of COX4)		 Mus musculus
TI:10090 None
 
EMC8_RAT
RGD»
4.5
Emc8 ER membrane protein complex
subunit 8 (Neighbor of COX4)		 Rattus norvegicus
TI:10116 None
 
EMC9_MOUSE
Ensembl»
4.5
Emc9 ER membrane protein complex
subunit 9 (Protein FAM158A)		 Mus musculus
TI:10090 None
 
EMC9_RAT
RGD»
4.5
Emc9 ER membrane protein complex
subunit 9 (Protein FAM158A)		 Rattus norvegicus
TI:10116 None
 
EMC8_HUMAN
Ensembl»
4.7
EMC8 ER membrane protein complex subunit
8 (Neighbor of COX4) (Protein FAM158B)		 Homo sapiens
TI:9606 None
 
EMC89_DROME
FlyBase»
4.8
EMC8-9 ER membrane protein complex subunit 8/9 homolog Drosophila melanogaster
TI:7227 None
 
EMC9_HUMAN
Ensembl»
4.7
EMC9 ER membrane protein complex
subunit 9 (Protein FAM158A)		 Homo sapiens
TI:9606 None
 
F1N8E6_CHICK
Ensembl»
1.5
EMC8 ER membrane protein complex subunit 8 Gallus gallus
TI:9031 None
   
EMC89_ARATH
TAIR»
1.5
EMB2731 ER membrane protein complex subunit
8/9 homolog (Protein EMBRYO DEFECTIVE 2731)		 Arabidopsis thaliana
TI:3702 None
 
Q93568_CAEEL
WormBase»
1.5
CELE_F25H2.4 F25H2.4 MPN domain-containing protein Caenorhabditis elegans
TI:6239 None
 
EMC89_DICDI
dictyBase»
1.5
DDB_G0268048 ER membrane protein complex subunit 8/9 homolog Dictyostelium discoideum
TI:44689 None
 
Q7ZUY2_DANRE
ZFIN»
1.5
emc8 Cox4 neighbor (ER membrane
protein complex subunit 8)		 Danio rerio
TI:7955 None
 
Q8AWD7_DANRE
ZFIN»
1.5
emc9 ER membrane protein
complex subunit 9 (Zgc:55317)		 Danio rerio
TI:7955 None
 
A0A1P8BFG8_ARATH
TAIR»
0.0
At5g51620 Uncharacterized protein family (UPF0172) Arabidopsis thaliana
TI:3702 None