Collated Gene Ontology terms

Biological process: single-stranded RNA binding(2016, 2017, 2023) RNA endonuclease activity(2016, 2017, 2023) hydrolase activity(2023) zinc ion binding(2016, 2023) metal ion binding(2023) nuclease activity(2023) endonuclease activity(2023) RNA binding(2023) ubiquitin protein ligase activity(2022) DNA binding(2023)

Molecular function: secondary metabolite biosynthetic process2012, 2013, 2015, 2022, 2023 RNA 3'-end processing2023 ubiquitin-dependent protein catabolic process2023 monodictyphenone biosynthetic process2012 endocrocin biosynthetic process2012 asperthecin biosynthetic process2012 anatomical structure development2023

Cellular component: mitochondrial matrix2016, 2017, 2023 membrane2023 mitochondrion2009, 2023 plastid2021 nucleus2019 extracellular region2012

Phylogenetic distribution

Chordates: 19/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 10/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 1/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 35/39 
Archea: 4/8 
Bacteria: 9/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 0 2 4 6 8 10 Knownness

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
LACB2_MOUSE
Ensembl»
4.0
Lactb2 Endoribonuclease LACTB2 (Beta-lactamase-like
protein 2) (EC 3.1.27.-)		 Mus musculus
TI:10090 None
 
LACB2_RAT
RGD»
4.0
Lactb2 Endoribonuclease LACTB2 (Beta-lactamase-like
protein 2) (EC 3.1.27.-)		 Rattus norvegicus
TI:10116 None
 
LACB2_DANRE
ZFIN»
2.5
lactb2 Endoribonuclease LACTB2 (Beta-lactamase-like
protein 2) (EC 3.1.27.-)		 Danio rerio
TI:7955 None
 
LACB2_BOVIN
Ensembl»
0.0
LACTB2 Endoribonuclease LACTB2 (Beta-lactamase-like
protein 2) (EC 3.1.27.-)		 Bos taurus
TI:9913 None
 
LACB2_HUMAN
Ensembl»
3.4
LACTB2 Endoribonuclease LACTB2 (EC
3.1.27.-) (Beta-lactamase-like protein 2)		 Homo sapiens
TI:9606 None
 
LACB2_XENTR
Xenbase»
0.0
lactb2 Endoribonuclease LACTB2 (Beta-lactamase-like
protein 2) (EC 3.1.27.-)		 Xenopus tropicalis
TI:8364 None
 
A0A2J8M9M4_PANTR
Ensembl»
0.0
LACTB2 Endoribonuclease LACTB2
(Beta-lactamase-like protein 2)		 Pan troglodytes
TI:9598 None
 
A0A5F7ZVN8_MACMU
Ensembl»
0.0
LACTB2 Endoribonuclease LACTB2
(Beta-lactamase-like protein 2)		 Macaca mulatta
TI:9544 None
   
F1RU12_PIG
Ensembl»
0.0
LACTB2 Endoribonuclease LACTB2
(Beta-lactamase-like protein 2)		 Sus scrofa
TI:9823 None
 
F6XC46_ORNAN
Ensembl»
0.0
LACTB2 Endoribonuclease LACTB2
(Beta-lactamase-like protein 2)		 Ornithorhynchus anatinus
TI:9258 None
   
F7FC68_MONDO
Ensembl»
0.0
LACTB2 Endoribonuclease LACTB2
(Beta-lactamase-like protein 2)		 Monodelphis domestica
TI:13616 None
   
G1KQC0_ANOCA
Ensembl»
0.0
LACTB2 Endoribonuclease LACTB2
(Beta-lactamase-like protein 2)		 Anolis carolinensis
TI:28377 None
   
G3SGF8_GORGO
Ensembl»
0.0
LACTB2 Endoribonuclease LACTB2
(Beta-lactamase-like protein 2)		 Gorilla gorilla
TI:9593 None
 
M3WKS1_FELCA
Ensembl»
0.0
LACTB2 Endoribonuclease LACTB2
(Beta-lactamase-like protein 2)		 Felis catus
TI:9685 None
 
LACB2_DROME
FlyBase»
1.0
CG12375 Beta-lactamase-like protein 2
homolog (EC 3.-.-.-)		 Drosophila melanogaster
TI:7227 None
 
TPCB_ASPFU
EnsemblFungi»
0.0
tpcB Atrochrysone carboxyl ACP thioesterase (ACTE)
(EC 3.1.2.-) (Trypacidin synthesis protein B)		 Aspergillus fumigatus
TI:746128 None
 
APTB_EMENI
EnsemblFungi»
0.0
aptB Lactamase-like protein aptB (EC
3.1.-.-) (Asperthecin synthesis protein B)		 Emericella nidulans
TI:162425 None
 
ENCB_ASPFU
EnsemblFungi»
0.0
encB Atrochrysone carboxyl ACP thioesterase (ACTE)
(EC 3.1.2.-) (Endocrocin synthesis protein B)		 Aspergillus fumigatus
TI:746128 None
 
LACB2_CAEEL
WormBase»
1.0
Y53F4B.39 Beta-lactamase-like protein 2
homolog (EC 3.-.-.-)		 Caenorhabditis elegans
TI:6239 None
 
MDPF_EMENI
EnsemblFungi»
0.0
mdpF Atrochrysone carboxyl ACP thioesterase (ACTE)
(EC 3.1.2.-) (Monodictyphenone synthesis protein F)		 Emericella nidulans
TI:162425 None
 
NSCB_ASPFU
EnsemblFungi»
0.0
nscB Lactamase-like protein nscB (EC
3.1.-.-) (Neosartoricin biosynthesis protein B)		 Aspergillus fumigatus
TI:746128 None
 
PKGB_EMENI
EnsemblFungi»
0.0
pkgB Thioesterase pkgB (EC 3.1.2.-)
(Pkg biosynthesis cluster protein B)		 Emericella nidulans
TI:162425 None
 
A0A8I3PYE9_CANLF
Ensembl»
0.0
LACTB2 Endoribonuclease LACTB2
(Beta-lactamase-like protein 2)		 Canis lupus
TI:9612 None
   
B7Q8W9_IXOSC
EnsemblMetazoa»
0.0
8037644 Metallo-beta-lactamase domain-containing protein Ixodes scapularis
TI:6945 None
 
D6WLP4_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_13413 Beta-lactamase-like protein 2 homolog Tribolium castaneum
TI:7070 None
 
E9GIK5_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_303870 Metallo-beta-lactamase domain-containing protein Daphnia pulex
TI:6669 None
 
Q7QB16_ANOGA
EnsemblMetazoa»
0.0
1274081 AGAP004236-PA Anopheles gambiae
TI:7165 None
 
A0A3B6FI88_WHEAT
EnsemblPlants»
0.0
CFC21_039328 Metallo-beta-lactamase domain-containing protein Triticum aestivum
TI:4565 None
 
A0A3B6GPH1_WHEAT
EnsemblPlants»
0.0
CFC21_045558 Metallo-beta-lactamase domain-containing protein Triticum aestivum
TI:4565 None
 
A0A7M7GF18_STRPU
EnsemblMetazoa»
0.0
Metallo-beta-lactamase domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A7SNX1_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g230617 Metallo-beta-lactamase domain-containing protein Nematostella vectensis
TI:45351 None
 
A8XYX6_CAEBR
WormBase»
0.0
CBG20910 CBG_20910 Protein CBG20910 Caenorhabditis briggsae
TI:6238 None
 
B3SA44_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_61129 Metallo-beta-lactamase domain-containing protein Trichoplax adhaerens
TI:10228 None
 
B3SA45_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_31980 Metallo-beta-lactamase domain-containing protein Trichoplax adhaerens
TI:10228 None
 
H2LML6_ORYLA
Ensembl»
0.0
LACTB2 Endoribonuclease LACTB2
(Beta-lactamase-like protein 2)		 Oryzias latipes
TI:8090 None
   
Q5B7B5_EMENI
EnsemblFungi»
0.0
ANIA_03565 Metallo-beta-lactamase domain protein,
putative (AFU_orthologue AFUA_3G00280)		 Emericella nidulans
TI:162425 None
 
Q682P6_ARATH
TAIR»
0.0
At1g25375 Metallo-hydrolase/oxidoreductase superfamily protein
(Uncharacterized protein At1g25375)		 Arabidopsis thaliana
TI:3702 None
 
T1G1F2_HELRO
EnsemblMetazoa»
0.0
20214900 Metallo-beta-lactamase domain-containing protein Helobdella robusta
TI:6412 None
 
W5M8V3_LEPOC
Ensembl»
0.0
LACTB2 Endoribonuclease LACTB2
(Beta-lactamase-like protein 2)		 Lepisosteus oculatus
TI:7918 None
 
A0A1Y1HW43_KLENI
EnsemblPlants»
0.0
KFL_000740020 Metallo-hydrolase/oxidoreductase
superfamily protein		 Klebsormidium nitens
TI:105231 None
 
C8VG91_EMENI
EnsemblFungi»
0.0
ANIA_05524 Metallo-beta-lactamase domain protein,
putative (AFU_orthologue AFUA_6G12940)		 Emericella nidulans
TI:162425 None
 
Q4WLN0_ASPFU
EnsemblFungi»
0.0
AFUA_6G12940 Metallo-beta-lactamase domain protein, putative Aspergillus fumigatus
TI:746128 None
 
A0A061E503_THECC
EnsemblPlants»
0.0
TCM_009592 Metallo-hydrolase/oxidoreductase superfamily
protein isoform 1		 Theobroma cacao
TI:3641 None
 
A0A067GB80_CITSI
Ensembl»
0.0
CISIN_1g009940mg Metallo-beta-lactamase domain-containing protein Citrus sinensis
TI:2711 None
 
A0A078HWC7_BRANA
EnsemblPlants»
0.0
BnaA09g28480D (rape) hypothetical
protein (BnaA09g28480D protein)		 Brassica napus
TI:3708 None
 
A0A0D1CW87_USTMA
EnsemblFungi»
0.0
UMAG_11901 Metallo-beta-lactamase domain-containing protein Ustilago maydis
TI:5270 None
 
A0A0K9Q562_ZOSMR
EnsemblPlants»
0.0
ZOSMA_112G00530 Metallo-beta-lactamase domain-containing protein Zostera marina
TI:29655 None
 
A0A0R0ELP8_SOYBN
EnsemblPlants»
0.0
100778510 Metallo-beta-lactamase domain-containing protein Glycine max
TI:3847 None
 
A0A1S3XJN4_TOBAC
EnsemblFungi»
0.0
LOC107765995 Uncharacterized protein LOC107765995 Nicotiana tabacum
TI:4097 None
   
A0A1S3XN26_TOBAC
EnsemblFungi»
0.0
LOC107766948 Uncharacterized protein LOC107766948 Nicotiana tabacum
TI:4097 None
   
A0A1U8APN5_NELNU
EnsemblBacteria»
0.0
LOC104602551 Uncharacterized protein LOC104602551 isoform X1 Nelumbo nucifera
TI:4432 None
 
A0A1U8ELJ5_CAPAN
EnsemblPlants»
0.0
T459_26814 Metallo-beta-lactamase domain-containing protein Capsicum annuum
TI:4072 None
 
A0A251R6V9_PRUPE
EnsemblPlants»
0.0
PRUPE_1G314400 Metallo-beta-lactamase domain-containing protein Prunus persica
TI:3760 None
 
A0A251RQA3_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr17g0551931 Putative metallo-hydrolase/oxidoreductase
superfamily protein		 Helianthus annuus
TI:4232 None
 
A0A2K1JEM4_PHYPA
EnsemblPlants»
0.0
PHYPA_020239 Metallo-beta-lactamase domain-containing protein Physcomitrium patens
TI:3218 None
 
A0A2R6X1K8_MARPO
EnsemblPlants»
0.0
MARPO_0042s0034 Metallo-beta-lactamase domain-containing protein Marchantia polymorpha
TI:3197 None
 
A0A3B6E9I6_WHEAT
EnsemblPlants»
0.0
CFC21_033602 Metallo-beta-lactamase domain-containing protein Triticum aestivum
TI:4565 None
 
A0A6P9DWS9_JUGRE
EnsemblPlants»
0.0
LOC109011987 Uncharacterized protein LOC109011987 isoform X1 Juglans regia
TI:51240 None
 
A0A8I6XP66_HORVV
EnsemblPlants»
0.0
Metallo-beta-lactamase domain-containing protein Hordeum vulgare
TI:4513 None
   
A0A9K3DJ00_HELAN
EnsemblPlants»
0.0
HanXRQr2_Chr17g0803921 Metallo-beta-lactamase, winged helix-like
DNA-binding domain superfamily		 Helianthus annuus
TI:4232 None
 
A7F0D6_SCLS1
EnsemblFungi»
0.0
SS1G_11053 LACTB2 winged helix domain-containing protein Sclerotinia sclerotiorum
TI:5180 None
 
B4F9F8_MAIZE
EnsemblPlants»
0.0
100191605 Metallo-hydrolase/oxidoreductase
superfamily protein		 Zea mays
TI:4577 None
 
E3KR96_PUCGT
EnsemblFungi»
0.0
PGTG_13203 Metallo-beta-lactamase domain-containing protein Puccinia graminis
TI:5297 None
 
F4NZ54_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_86882 Metallo-beta-lactamase domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
F4P0R8_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_24208 Metallo-beta-lactamase domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
G7IC92_MEDTR
EnsemblPlants»
0.0
11421877 Metallo-beta-lactamase superfamily protein Medicago truncatula
TI:3880 None
 
I6XHY3_MYCTU
TubercuList»
0.0
Rv3677c Possible hydrolase Mycobacterium tuberculosis
TI:1773 None
 
K3XUN7_SETIT
EnsemblPlants»
0.0
LACTB2 winged helix domain-containing protein Setaria italica
TI:4555 None
 
Q0U7Q7_PHANO
EnsemblFungi»
0.0
SNOG_12207 Metallo-beta-lactamase domain-containing protein Phaeosphaeria nodorum
TI:13684 None
 
Q5KE04_CRYNJ
EnsemblFungi»
0.0
CNG02190 Metallo-beta-lactamase domain-containing protein Cryptococcus neoformans
TI:5207 None
 
Q6C173_YARLI
EnsemblFungi»
0.0
YALI0_F18678g YALI0F18678p Yarrowia lipolytica
TI:4952 None
 
Q7S4V1_NEUCR
EnsemblFungi»
0.0
NCU02376 Metallo-beta-lactamase domain-containing protein Neurospora crassa
TI:5141 None
 
Q8F1D2_LEPIN
EnsemblBacteria»
0.0
LA_3205 Zn-dependent hydrolase Leptospira interrogans
TI:173 None
 
Q9XA41_STRCO
EnsemblBacteria»
0.0
SCO3572 Hydrolase Streptomyces coelicolor
TI:1902 None
 
A0A022RKP3_ERYGU
Ensembl»
0.0
MIMGU_mgv1a007780mg Metallo-beta-lactamase domain-containing protein Erythranthe guttata
TI:4155 None 		 
 
A0A059D6D8_EUCGR
EnsemblPlants»
0.0
EUGRSUZ_B02995 Metallo-beta-lactamase domain-containing protein Eucalyptus grandis
TI:71139 None 		 
 
A0A0P0UXY3_ORYSJ
EnsemblPlants»
0.0
Os01g0133500 Os01g0133500 protein Oryza sativa
TI:4530 None 		 
 
A0A0R0HZQ1_SOYBN
EnsemblPlants»
0.0
GLYMA_10G272100 LACTB2 winged helix domain-containing protein Glycine max
TI:3847 None 		 
 
A0A1B6Q205_SORBI
EnsemblPlants»
0.0
SORBI_3003G083900 Metallo-beta-lactamase domain-containing protein Sorghum bicolor
TI:4558 None 		 
 
A0A1U8HJE9_GOSHI
Ensembl»
0.0
LOC107886651 Uncharacterized protein LOC107886651 isoform X1
(Uncharacterized protein LOC107886651 isoform X2)		 Gossypium hirsutum
TI:3635 None 		     
A0A2A6CPP2_PRIPA
EnsemblMetazoa»
0.0
WBGene00280128 Metallo-beta-lactamase domain-containing protein Pristionchus pacificus
TI:54126 None 		 
 
A0A2C9UKP3_MANES
EnsemblPlants»
0.0
MANES_14G105200 Metallo-beta-lactamase domain-containing protein Manihot esculenta
TI:3983 None 		 
 
A0A2K1YSW3_POPTR
EnsemblPlants»
0.0
POPTR_010G122100 Metallo-beta-lactamase domain-containing protein Populus trichocarpa
TI:3694 None 		 
 
A0A3Q7GDC4_SOLLC
EnsemblPlants»
0.0
Metallo-beta-lactamase domain-containing protein Solanum lycopersicum
TI:4081 None 		     
A0A6P9DYC8_JUGRE
EnsemblPlants»
0.0
LOC109011987 Uncharacterized protein LOC109011987 isoform X2 Juglans regia
TI:51240 None 		 
 
A0A804JUU2_MUSAM
EnsemblPlants»
0.0
GSMUA_43180.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None 		 
 
A0A8V0XK56_CHICK
Ensembl»
0.0
LACTB2 Endoribonuclease LACTB2
(Beta-lactamase-like protein 2)		 Gallus gallus
TI:9031 None 		     
A0A9J7HIM5_BRAFL
CTD»
0.0
LOC118405058 Endoribonuclease LACTB2
(Beta-lactamase-like protein 2)		 Branchiostoma floridae
TI:7739 None 		     
A0CHE7_PARTE
EnsemblProtists»
0.0
GSPATT00038316001 Chromosome undetermined scaffold_180,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None 		 
 
A0DJC9_PARTE
EnsemblProtists»
0.0
GSPATT00017490001 Chromosome undetermined scaffold_53,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None 		 
 
A5HZK9_CLOBH
Ensembl»
0.0
CBO0666 Metallo-beta-lactamase superfamily potein Clostridium botulinum
TI:1491 None 		 
 
A9A2L5_NITMS
EnsemblBacteria»
0.0
Nmar_1358 Beta-lactamase domain protein Nitrosopumilus maritimus
TI:338192 None 		 
 
A9A3H9_NITMS
EnsemblBacteria»
0.0
Nmar_1015 Proteinase inhibitor I1 Kazal Nitrosopumilus maritimus
TI:338192 None 		 
 
A9WHZ2_CHLAA
EnsemblBacteria»
0.0
Caur_2476 Beta-lactamase domain protein Chloroflexus aurantiacus
TI:1108 None 		 
 
B9SLY7_RICCO
EnsemblBacteria»
0.0
RCOM_1310050 Catalytic, putative Ricinus communis
TI:3988 None 		 
 
D7T920_VITVI
EnsemblPlants»
0.0
VIT_01s0011g03830 Metallo-beta-lactamase domain-containing protein Vitis vinifera
TI:29760 None 		 
 
D8S6U4_SELML
EnsemblPlants»
0.0
SELMODRAFT_56114 Metallo-beta-lactamase domain-containing protein Selaginella moellendorffii
TI:88036 None 		 
 
D8T7B0_SELML
EnsemblPlants»
0.0
SELMODRAFT_133694 Metallo-beta-lactamase domain-containing protein Selaginella moellendorffii
TI:88036 None 		 
 
F0ZFS4_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_87074 Metallo-beta-lactamase domain-containing protein Dictyostelium purpureum
TI:5786 None 		 
 
H3GXW4_PHYRM
EnsemblProtists»
0.0
Metallo-beta-lactamase domain-containing protein Phytophthora ramorum
TI:164328 None 		 
 
I1HBQ3_BRADI
EnsemblPlants»
0.0
100840116 Metallo-beta-lactamase domain-containing protein Brachypodium distachyon
TI:15368 None 		 
 
K3XJE8_SETIT
EnsemblPlants»
0.0
Metallo-beta-lactamase domain-containing protein Setaria italica
TI:4555 None 		 
 
M1B5S9_SOLTU
EnsemblPlants»
0.0
Metallo-beta-lactamase domain-containing protein Solanum tuberosum
TI:4113 None 		     
Q4QCE8_LEIMA
EnsemblProtists»
0.0
LMJF_21_0670 Metallo-beta-lactamase family-like protein Leishmania major
TI:5664 None 		 
 
Q54YG0_DICDI
dictyBase»
0.0
DDB_G0278253 Metallo-beta-lactamase domain-containing protein Dictyostelium discoideum
TI:44689 None 		 
 
Q7UGS7_RHOBA
EnsemblBacteria»
0.0
RB5042 Metallo-beta-lactamase domain-containing protein Rhodopirellula baltica
TI:265606 None 		 
 
Q89RZ5_BRADU
EnsemblBacteria»
0.0
blr2617 Metallo-beta-lactamase superfamily protein Bradyrhizobium diazoefficiens
TI:1355477 None 		 
 
Q89V56_BRADU
EnsemblBacteria»
0.0
bll1202 Bll1202 protein Bradyrhizobium diazoefficiens
TI:1355477 None 		 
 
Q8RE48_FUSNN
EnsemblBacteria»
0.0
FN1279 Zinc metallohydrolase, glyoxalase II family Fusobacterium nucleatum
TI:851 None 		 
 
Q8ZT88_PYRAE
EnsemblBacteria»
0.0
PAE3376 Beta-lactamase-like protein Pyrobaculum aerophilum
TI:13773 None 		 
 
Q97VU4_SACS2
EnsemblBacteria»
0.0
SSO2515 Metallo-beta-lactamase domain-containing protein Saccharolobus solfataricus
TI:2287 None 		 
 
Q9HRG5_HALSA
EnsemblBacteria»
0.0
VNG_0709C Metallo-beta-lactamase domain-containing protein Halobacterium salinarum
TI:2242 None 		 
 
Q9HSD1_HALSA
EnsemblBacteria»
0.0
VNG_0291H Beta-lactamase domain protein Halobacterium salinarum
TI:2242 None 		 
 
Q9RSP8_DEIRA
EnsemblBacteria»
0.0
DR_2076 Metallo-beta-lactamase domain-containing protein Deinococcus radiodurans
TI:1299 None 		 
 
U5G1M9_POPTR
EnsemblPlants»
0.0
POPTR_010G122000 Metallo-beta-lactamase domain-containing protein Populus trichocarpa
TI:3694 None 		 
 
W1PAI4_AMBTC
EnsemblPlants»
0.0
AMTR_s00079p00177100 Metallo-beta-lactamase domain-containing protein Amborella trichopoda
TI:13333 None