Collated Gene Ontology terms

Biological process: NAD+ poly-ADP-ribosyltransferase activity(2025) transmembrane signaling receptor activity(2025) transferase activity(2025) monoatomic ion channel activity(2025) heme binding(2012) extracellular ligand-gated monoatomic ion channel activity(2025) excitatory extracellular ligand-gated monoatomic ion channel activity(2023) chloride channel activity(2024)

Molecular function: protein insertion into mitochondrial outer membrane2013, 2021, 2025 mitochondrial outer membrane translocase complex assembly2013, 2024, 2025 protein transport2025 mitochondrion organization2014, 2025 mitochondrial transport2003, 2021, 2025 stress response to cadmium ion2014 protein targeting to mitochondrion2008, 2025 inner mitochondrial membrane organization2020 protein import into mitochondrial matrix2024, 2025 phospholipid transport2013, 2025
lactation2017, 2025 axonogenesis2006 secondary metabolic process2010 regulation of protein deneddylation2012 monoatomic ion transport2025 monoatomic ion transmembrane transport2025 innate immune response2014 fungal-type cell wall organization or biogenesis2014 female germ-line stem cell population maintenance2018 excitatory postsynaptic potential2025 endoplasmic reticulum unfolded protein response2017 chloride transmembrane transport2024 axonal transport of mitochondrion2025 IRE1-mediated unfolded protein response2018

Cellular component: SAM complex2013, 2016, 2020, 2021, 2024, 2025 mitochondrial outer membrane2003, 2007, 2008, 2011, 2015, 2018, 2025 mitochondrion2009, 2012, 2017, 2018, 2019, 2021, 2024, 2025 cytoplasm2014, 2018, 2025 membrane2003, 2004, 2025 cell tip2018, 2025 mitochondrial inner membrane2005, 2019, 2025 MIB complex2020 plasma membrane2014, 2025 nucleus2018, 2025
lysosome2013, 2014 endoplasmic reticulum2018, 2025 postsynapse2025 nucleolus2025 axon cytoplasm2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 39/39 
Archea: 0/8 
Bacteria: 2/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
SAM37_YEAST
SGD»
4.2
SAM37 Sorting assembly machinery 37 kDa subunit (MAS37
protein) (Mitochondrial 37 kDa outer membrane protein)		 Saccharomyces cerevisiae
TI:4932 None
 
MTX_ARATH
TAIR»
1.8
MTX1 Mitochondrial outer membrane
import complex protein METAXIN		 Arabidopsis thaliana
TI:3702 None
 
MTXL_SCHPO
PomBase»
1.0
SPBC409.19c Metaxin-like protein C409.19c Schizosaccharomyces pombe
TI:4896 None
 
MTX3_DANRE
ZFIN»
1.0
mtx3 Metaxin-3 (zMTX3) Danio rerio
TI:7955 None
 
MTX3_HUMAN
Ensembl»
2.0
MTX3 Metaxin-3 Homo sapiens
TI:9606 None
 
MTX2_CAEEL
WormBase»
1.0
mtx-2 Metaxin-2 homolog (Mitochondrial outer
membrane import complex protein 2)		 Caenorhabditis elegans
TI:6239 None
 
A0A8I5ZLV1_RAT
RGD»
0.0
Mtx2 Metaxin-2 (Mitochondrial outer membrane
import complex protein 2)		 Rattus norvegicus
TI:10116 None
   
E1BVN1_CHICK
Ensembl»
0.0
MTX2 Metaxin-2 (Mitochondrial outer membrane
import complex protein 2)		 Gallus gallus
TI:9031 None
   
MTX2_HUMAN
Ensembl»
4.3
MTX2 Metaxin-2 (Mitochondrial outer membrane
import complex protein 2)		 Homo sapiens
TI:9606 None
 
MTX2_MOUSE
Ensembl»
2.0
Mtx2 Metaxin-2 (Mitochondrial outer membrane
import complex protein 2)		 Mus musculus
TI:10090 None
 
Q6WFZ4_DANRE
ZFIN»
1.0
mtx2 Metaxin-2 (Mitochondrial outer membrane
import complex protein 2)		 Danio rerio
TI:7955 None
 
MTX1_CAEEL
WormBase»
1.0
mtx-1 Metaxin-1 homolog (Mitochondrial outer
membrane import complex protein 1)		 Caenorhabditis elegans
TI:6239 None
 
MTX1_DROME
FlyBase»
1.5
CG9393 Metaxin-1 homolog (Mitochondrial outer
membrane import complex protein 1)		 Drosophila melanogaster
TI:7227 None
 
A0A0G2JU49_RAT
RGD»
1.8
Mtx1 Metaxin-1 (Mitochondrial outer membrane
import complex protein 1)		 Rattus norvegicus
TI:10116 None
   
MTX1_HUMAN
Ensembl»
2.6
MTX1 Metaxin-1 (Mitochondrial outer membrane
import complex protein 1)		 Homo sapiens
TI:9606 None
 
MTX1_MOUSE
AG»
1.0
Mtx1 Metaxin-1 (Mitochondrial outer membrane
import complex protein 1)		 Mus musculus
TI:10090 None
 
MTX1_SCHPO
PomBase»
1.0
mtx1 Metaxin-1 Schizosaccharomyces pombe
TI:4896 None
 
A0A8M9PR98_DANRE
ZFIN»
0.0
mtx1b Metaxin Danio rerio
TI:7955 None
   
A0ABK0LPS2_RAT
Ensembl»
0.0
Mtx3 Metaxin Rattus norvegicus
TI:10116 None
   
A2THY5_DANRE
ZFIN»
1.0
mtx1a Metaxin Danio rerio
TI:7955 None
 
D3YTP3_MOUSE
Ensembl»
1.0
Mtx3 Metaxin Mus musculus
TI:10090 None
   
F6TYJ6_CHICK
Ensembl»
1.0
MTX3 Metaxin Gallus gallus
TI:9031 None
   
Q9VW58_DROME
FlyBase»
2.3
Mtx2 LD33138p Drosophila melanogaster
TI:7227 None
 
Q86JB5_DICDI
dictyBase»
0.0
DDB_G0276899 Glutathione S-transferase
domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
Q8MQC1_CAEEL
WormBase»
0.0
C25H3.7 CELE_C25H3.7 GST_C_6 domain-containing protein Caenorhabditis elegans
TI:6239 None 		 
 
V6CM17_CAEEL
WormBase»
0.0
CELE_F53G12.9 F53G12.9 GST_C_6 domain-containing protein Caenorhabditis elegans
TI:6239 None 		 
 
Q9NA74_CAEEL
WormBase»
0.0
faxc-1 GST N-terminal domain-containing protein Caenorhabditis elegans
TI:6239 None 		 
 
E1C3J5_CHICK
Ensembl»
0.0
FAXC Failed axon connections homolog,
metaxin like GST domain containing		 Gallus gallus
TI:9031 None 		     
A0A8N7TB71_DANRE
ZFIN»
0.0
faxcb Failed axon connections homolog Danio rerio
TI:7955 None 		     
E7FFZ1_DANRE
ZFIN»
0.0
faxca Failed axon connections homolog Danio rerio
TI:7955 None 		 
 
FAXC_HUMAN
Ensembl»
0.0
FAXC Failed axon connections homolog Homo sapiens
TI:9606 None
 
FAXC_MOUSE
Ensembl»
0.0
Faxc Failed axon connections homolog Mus musculus
TI:10090 None
 
FAXC_RAT
RGD»
0.0
Faxc Failed axon connections homolog Rattus norvegicus
TI:10116 None
 
Q9NAG5_CAEEL
WormBase»
0.0
faxc-2 Failed axon connections homolog Caenorhabditis elegans
TI:6239 None 		 
 
FAXC_DROME
FlyBase»
2.5
fax Failed axon connections Drosophila melanogaster
TI:7227 None
 
G5EGC7_CAEEL
WormBase»
0.8
hrg-2 Cadmium-inducible lysosomal protein CDR-5
(GST C-terminal domain-containing protein)		 Caenorhabditis elegans
TI:6239 None
 
G5EBH4_CAEEL
WormBase»
0.0
cdr-7 CaDmium Responsive (Cadmium-inducible
lysosomal protein CDR-7)		 Caenorhabditis elegans
TI:6239 None 		 
 
G5ECX9_CAEEL
WormBase»
2.4
cdr-2 CaDmium Responsive (Cadmium-inducible
lysosomal protein CDR-2)		 Caenorhabditis elegans
TI:6239 None
 
G5EDZ7_CAEEL
WormBase»
2.3
cdr-4 CaDmium Responsive (Cadmium-inducible
lysosomal protein CDR-4)		 Caenorhabditis elegans
TI:6239 None
 
G5EE89_CAEEL
WormBase»
1.6
cdr-1 CaDmium Responsive (Cadmium-inducible
lysosomal protein CDR-1)		 Caenorhabditis elegans
TI:6239 None
 
G5EET3_CAEEL
WormBase»
0.0
cdr-6 CaDmium Responsive (Cadmium-inducible
lysosomal protein CDR-6)		 Caenorhabditis elegans
TI:6239 None 		 
 
Q18832_CAEEL
WormBase»
0.8
cdr-3 CaDmium Responsive Caenorhabditis elegans
TI:6239 None
 
Q8T4F2_DROME
FlyBase»
1.5
Dmel\CG5662 AT01806p (Uncharacterized protein, isoform
A) (Uncharacterized protein, isoform B)		 Drosophila melanogaster
TI:7227 None