Collated Gene Ontology terms

Biological process: guanyl-nucleotide exchange factor activity(2013, 2014, 2021, 2025) small GTPase binding(2014, 2015, 2025)

Molecular function: retrograde transport, endosome to Golgi2013, 2014, 2015, 2018, 2024, 2025 negative regulation of protein catabolic process2014, 2025 positive regulation of GTPase activity2014, 2025 regulation of cartilage development2024 positive regulation of TORC2 signaling2016 pollen tube growth2018 extracellular matrix constituent secretion2024 cell division2025 cartilage development2021

Cellular component: Ric1-Rgp1 guanyl-nucleotide exchange factor complex2013, 2014, 2021, 2025 cytosol2009, 2014, 2015, 2025 Golgi membrane2013, 2017 membrane2014, 2025 protein-containing complex2014, 2025 Golgi apparatus2019, 2024, 2025 nucleus2009, 2018 trans-Golgi network membrane2015 pollen tube2018 plasma membrane2025
guanyl-nucleotide exchange factor complex2013 cytoplasm2025 Golgi cisterna2018

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
B9HGM4_POPTR
neXtProt»
0.0
POPTR_007G071000 Reduced growth phenotype protein 1 Populus trichocarpa
TI:3694 None
 
K7DI32_PANTR
Ensembl»
0.0
RGP1 RGP1 homolog, RAB6A GEF complex partner
1 (RGP1 retrograde golgi transport homolog)		 Pan troglodytes
TI:9598 None
 
B7Q8G5_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW021546 RAB6A-GEF complex partner protein 2 Ixodes scapularis
TI:6945 None
 
RGP1_HUMAN
Ensembl»
4.5
RGP1 RAB6A-GEF complex partner protein 2
(Retrograde Golgi transport protein RGP1 homolog)		 Homo sapiens
TI:9606 None
 
RGP1_MOUSE
Ensembl»
5.5
Rgp1 RAB6A-GEF complex partner protein 2
(Retrograde Golgi transport protein RGP1 homolog)		 Mus musculus
TI:10090 None
 
K4A824_SETIT
EnsemblPlants»
0.0
LOC101777991 Uncharacterized protein Setaria italica
TI:4555 None
 
Q8RWU2_ARATH
TAIR»
1.6
LOT Immunoglobulin Arabidopsis thaliana
TI:3702 None
 
RGP1_YEAST
SGD»
4.3
RGP1 Guanine nucleotide exchange factor subunit RGP1
(Reduced growth phenotype protein 1) (Rgp1p)		 Saccharomyces cerevisiae
TI:4932 None
 
A0A078I5A6_BRANA
neXtProt»
0.0
BnaA08g02240D (rape) hypothetical
protein (BnaA08g02240D protein)		 Brassica napus
TI:3708 None
 
A0A1D6DU37_MAIZE
EnsemblPlants»
0.0
LOC100272345 RAB6A-GEF complex partner protein 2 Zea mays
TI:4577 None
 
G7LDH4_MEDTR
EnsemblPlants»
0.0
11431112 Putative reduced growth
phenotype protein (Rgp1 protein)		 Medicago truncatula
TI:3880 None
 
I1GX95_BRADI
EnsemblPlants»
0.0
LOC100826423 Uncharacterized protein Brachypodium distachyon
TI:15368 None
 
I1HG03_BRADI
EnsemblPlants»
0.0
LOC100825290 Uncharacterized protein Brachypodium distachyon
TI:15368 None
 
K7KE67_SOYBN
EnsemblPlants»
0.0
LOC100795634 Reduced growth phenotype protein 1 Glycine max
TI:3847 None
 
K7L119_SOYBN
EnsemblPlants»
0.0
LOC100812423 Uncharacterized protein Glycine max
TI:3847 None
 
M5X3V9_PRUPE
neXtProt»
0.0
PRUPE_2G113700 Reduced growth phenotype protein 1 Prunus persica
TI:3760 None
 
Q580A2_TRYB2
TubercuList»
0.0
Tb04.5E12.950 Rgp1 Trypanosoma brucei
TI:5691 None
 
Q6DHI8_DANRE
ZFIN»
2.9
rgp1 GP1 homolog, RAB6A GEF complex partner 1 (RAB6A-GEF complex
partner protein 2) (RGP1 retrograde golgi transport homolog (S. cerevisiae))		 Danio rerio
TI:7955 None
 
SAT1_SCHPO
PomBase»
2.1
sat1 Protein sat1 Schizosaccharomyces pombe
TI:4896 None
 
T1FNV1_HELRO
EnsemblMetazoa»
0.0
20210498 Uncharacterized protein Helobdella robusta
TI:6412 None
 
A0A022Q7Q4_ERYGU
euHCVdb»
0.0
MIMGU_mgv1a005131mg Uncharacterized protein Erythranthe guttata
TI:4155 None
 
A0A061E3F3_THECC
euHCVdb»
0.0
TCM_007741 Immunoglobulin E-set Theobroma cacao
TI:3641 None
 
A0A067EFW1_CITSI
neXtProt»
0.0
CISIN_1g008822mg Reduced growth phenotype protein 1 Citrus sinensis
TI:2711 None
 
A0A078JH09_BRANA
euHCVdb»
0.0
BnaAnng23150D BnaAnng23150D protein Brassica napus
TI:3708 None
 
A0A078JWF7_BRANA
euHCVdb»
0.0
BnaAnng31920D BnaAnng31920D protein Brassica napus
TI:3708 None
 
A0A0A0KVN2_CUCSA
euHCVdb»
0.0
Csa_4G099730 Uncharacterized protein Cucumis sativus
TI:3659 None 		 
 
A0A0A0L0L6_CUCSA
euHCVdb»
0.0
Csa_4G099740 Reduced growth phenotype protein 1 Cucumis sativus
TI:3659 None
 
A0A0C4DHA5_DROME
FlyBase»
1.5
Rgp1 Uncharacterized protein, isoform D Drosophila melanogaster
TI:7227 None
 
A0A0K9NPB7_ZOSMR
neXtProt»
0.0
ZOSMA_80G00240 Reduced growth phenotype protein 1 Zostera marina
TI:29655 None
 
A0A1D8PGU6_CANAL
CGD»
0.0
CAALFM_C203340WA orf19.8513 Rgp1p Candida albicans
TI:5476 None
 
A0A1W3JNK5_CIOIN
Ensembl»
0.0
LOC100185231 RAB6A-GEF complex partner protein 2 Ciona intestinalis
TI:7719 None
 
A0A1Y1HR10_KLENI
euHCVdb»
0.0
KFL_000220380 Reduced growth phenotype protein 1 Klebsormidium nitens
TI:105231 None
 
A0A251T651_HELAN
neXtProt»
0.0
HannXRQ_Chr12g0379741 Reduced growth phenotype protein 1 Helianthus annuus
TI:4232 None
 
A0A2C9W2P6_MANES
euHCVdb»
0.0
MANES_04G103500v8 Reduced growth phenotype protein 1 Manihot esculenta
TI:3983 None
 
A0A2G2ZN31_CAPAN
euHCVdb»
0.0
T459_11840 RAB6A-GEF complex partner protein 2 Capsicum annuum
TI:4072 None
 
A0A2K1IK26_PHYPA
EnsemblPlants»
0.0
LOC112276079 Uncharacterized protein Physcomitrium patens
TI:3218 None
 
A0A2K1IUC8_PHYPA
EnsemblPlants»
0.0
LOC112273334 Uncharacterized protein Physcomitrium patens
TI:3218 None
 
A0A2R6XAR3_MARPO
euHCVdb»
0.0
MARPO_0026s0045 Uncharacterized protein Marchantia polymorpha
TI:3197 None
 
A0A7U2EWH6_PHANO
TubercuList»
0.0
JI435_075520 Rgp1-domain-containing protein Phaeosphaeria nodorum
TI:13684 None 		 
 
A0A9K3HJ77_HELAN
neXtProt»
0.0
HanXRQr2_Chr12g0557661 Reduced growth phenotype protein Helianthus annuus
TI:4232 None 		 
 
A0A9R1VG70_LACSA
neXtProt»
0.0
LSAT_V11C500242730 Reduced growth phenotype protein 1 Lactuca sativa
TI:4236 None
 
A7EJ74_SCLS1
TubercuList»
0.0
SS1G_05367 Rgp1-domain-containing protein Sclerotinia sclerotiorum
TI:5180 None
 
A7SX95_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g136515 RAB6A-GEF complex partner protein 2 Nematostella vectensis
TI:45351 None
 
A8HXV4_CHLRE
euHCVdb»
0.0
CHLRE_06g258400v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None
 
A8X9M2_CAEBR
WormBase»
0.0
CBG09782 CBG_09782 Protein CBG09782 Caenorhabditis briggsae
TI:6238 None
 
A9UQU8_MONBE
euHCVdb»
0.0
MONBRDRAFT_5392 Uncharacterized protein Monosiga brevicollis
TI:81824 None
 
B3RSC1_TRIAD
CTD»
0.0
TRIADDRAFT_54544 Arrestin C-terminal-like
domain-containing protein		 Trichoplax adhaerens
TI:10228 None
 
B9RWY2_RICCO
euHCVdb»
0.0
RCOM_1705410 Uncharacterized protein Ricinus communis
TI:3988 None
 
C5YA37_SORBI
euHCVdb»
0.0
SORBI_3006G260500 Uncharacterized protein Sorghum bicolor
TI:4558 None
 
D6WQI4_TRICA
neXtProt»
0.0
AUGUSTUS-3.0.2_09939 Retrograde Golgi transport
protein RGP1 homolog-like Protein		 Tribolium castaneum
TI:7070 None
 
D7T9G4_VITVI
neXtProt»
0.0
VIT_01s0011g02190 RAB6A-GEF complex partner protein 2 Vitis vinifera
TI:29760 None
 
D8QPX6_SELML
neXtProt»
0.0
SELMODRAFT_73467 Uncharacterized protein Selaginella moellendorffii
TI:88036 None
 
D8SKJ3_SELML
neXtProt»
0.0
SELMODRAFT_119132 Uncharacterized protein Selaginella moellendorffii
TI:88036 None
 
E3L7Z6_PUCGT
TubercuList»
0.0
PGTG_18186 Uncharacterized protein Puccinia graminis
TI:5297 None
 
E9FUY6_DAPPU
neXtProt»
0.0
DAPPUDRAFT_221054 RAB6A-GEF complex partner protein 2 Daphnia pulex
TI:6669 None
 
F0ZWF3_DICPU
TubercuList»
0.0
DICPUDRAFT_82408 Rgp1-domain-containing protein Dictyostelium purpureum
TI:5786 None
 
F1STB5_PIG
Ensembl»
0.0
RGP1 RAB6A-GEF complex partner protein 2 (RGP1
homolog, RAB6A GEF complex partner 1)		 Sus scrofa
TI:9823 None
 
F4NRH5_BATDJ
euHCVdb»
0.0
BATDEDRAFT_34132 Rgp1-domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
F7GRM3_MACMU
Ensembl»
0.0
RGP1 RGP1 homolog, RAB6A GEF complex partner
1 (Retrograde Golgi transport protein RGP1 homolog)		 Macaca mulatta
TI:9544 None
 
G3QWP8_GORGO
Ensembl»
0.0
RGP1 RGP1 homolog, RAB6A GEF complex partner 1 Gorilla gorilla
TI:9593 None
 
H3GGV6_PHYRM
EnsemblProtists»
0.0
Rgp1-domain-containing protein Phytophthora ramorum
TI:164328 None
 
Q0DAX4_ORYSJ
euHCVdb»
0.0
Os06g0618600 Os06g0618600 protein Oryza sativa
TI:4530 None 		 
 
Q1K8Z5_NEUCR
TubercuList»
0.0
NCU06774 Intracellular protein transporter Neurospora crassa
TI:5141 None
 
Q4Q2E2_LEIMA
TubercuList»
0.0
LMJF_34_3990 Arrestin-like N-terminal
domain-containing protein		 Leishmania major
TI:5664 None
 
Q4X0T3_ASPFU
TubercuList»
0.0
AFUA_2G12380 Intracellular protein transport
protein (Sat1), putative		 Aspergillus fumigatus
TI:746128 None
 
Q5AZJ1_EMENI
TubercuList»
0.0
ANIA_06289 Intracellular protein transport protein
(Sat1), putative (AFU_orthologue AFUA_2G12380)		 Emericella nidulans
TI:162425 None
 
Q5KM32_CRYD1
TubercuList»
0.0
CNB03170 Expressed protein Cryptococcus deneoformans
TI:40410 None
 
Q5M7P9_XENTR
Xenbase»
0.0
rgp1 Hypothetical LOC496821 (RGP1 homolog,
RAB6A GEF complex partner 1)		 Xenopus tropicalis
TI:8364 None 		 
 
Q6BZZ5_YARLI
TubercuList»
0.0
YALI0_F29513g YALI0F29513p Yarrowia lipolytica
TI:4952 None
 
Q6GQ74_XENLA
Xenbase»
0.0
rgp1.L MGC80288 protein (RGP1 homolog, RAB6A
GEF complex partner 1 L homeolog)		 Xenopus laevis
TI:8355 None 		 
 
Q750W8_EREGS
euHCVdb»
0.0
AGOS_AGL179C AGL179Cp Eremothecium gossypii
TI:33169 None
 
Q76NU4_DICDI
dictyBase»
0.5
DG1122 E set domain-containing protein Dictyostelium discoideum
TI:44689 None
 
Q7PGR9_ANOGA
EnsemblMetazoa»
0.0
1272908 AGAP003042-PA Anopheles gambiae
TI:7165 None
 
Q7YWW8_CAEEL
WormBase»
0.5
CELE_M01F1.9 M01F1.9 Arrestin_N domain-containing protein Caenorhabditis elegans
TI:6239 None
 
RGP1_BOVIN
euHCVdb»
0.0
RGP1 RAB6A-GEF complex partner protein 2
(Retrograde Golgi transport protein RGP1 homolog)		 Bos taurus
TI:9913 None
 
T0S361_SCHJY
TubercuList»
0.0
rgp1 Uncharacterized protein Schizosaccharomyces japonicus
TI:4897 None
 
W1PUS8_AMBTC
euHCVdb»
0.0
AMTR_s00022p00174260 Uncharacterized protein Amborella trichopoda
TI:13333 None
 
W5MT31_LEPOC
Ensembl»
0.0
GP1 homolog, RAB6A GEF complex partner 1 Lepisosteus oculatus
TI:7918 None
 
A0A1S4A9K8_TOBAC
euHCVdb»
0.0
LOC107795206 Uncharacterized protein LOC107795206 isoform
X1 (Uncharacterized protein isoform X1)		 Nicotiana tabacum
TI:4097 None
   
A0A1U7Z7A0_NELNU
euHCVdb»
0.0
LOC104591851 Uncharacterized protein LOC104591851 isoform X1 Nelumbo nucifera
TI:4432 None
   
A0A1U7ZCR1_NELNU
neXtProt»
0.0
LOC104592759 Uncharacterized protein LOC104592759 Nelumbo nucifera
TI:4432 None
   
A0A1U8IVJ2_GOSHI
euHCVdb»
0.0
LOC107898860 Uncharacterized protein isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A1U8N9N6_GOSHI
euHCVdb»
0.0
LOC107946109 Uncharacterized protein LOC107946109 isoform
X1 (Uncharacterized protein isoform X1)		 Gossypium hirsutum
TI:3635 None
   
A0A2I4EHW4_JUGRE
euHCVdb»
0.0
LOC108989724 Uncharacterized protein LOC108989724 Juglans regia
TI:51240 None
   
A0A310UEC9_XENLA
Xenbase»
0.0
rgp1.S RAB6A-GEF complex partner protein 2 Xenopus laevis
TI:8355 None
   
A0A3B6GPK8_WHEAT
EnsemblPlants»
0.0
Uncharacterized protein Triticum aestivum
TI:4565 None
   
A0A3B6RJK0_WHEAT
EnsemblPlants»
0.0
LOC123148455 Uncharacterized protein Triticum aestivum
TI:4565 None
   
A0A3B6SKF2_WHEAT
EnsemblPlants»
0.0
LOC123156522 Uncharacterized protein Triticum aestivum
TI:4565 None
   
A0A3B6TVQ1_WHEAT
EnsemblPlants»
0.0
LOC123164607 Uncharacterized protein Triticum aestivum
TI:4565 None 		     
A0A7M7N932_STRPU
EnsemblMetazoa»
0.0
RAB6A-GEF complex partner protein 2 Strongylocentrotus purpuratus
TI:7668 None
   
A0A804HTG0_MUSAM
EnsemblPlants»
0.0
Reduced growth phenotype protein 1 Musa acuminata
TI:4641 None
   
A0A8I3NCY8_CANLF
Ensembl»
0.0
RGP1 RGP1 homolog, RAB6A GEF complex partner 1 Canis lupus
TI:9612 None
   
A0A8I5ZYV2_RAT
RGD»
3.0
Rgp1 RGP1 homolog, RAB6A GEF complex partner 1 Rattus norvegicus
TI:10116 None
   
A0A8I6Z709_HORVV
EnsemblPlants»
0.0
LOC123407518 RAB6A-GEF complex partner protein 2 Hordeum vulgare
TI:4513 None
   
A0A9J7KMH1_BRAFL
euHCVdb»
0.0
LOC118409639 RAB6A-GEF complex partner
protein 2-like isoform X1		 Branchiostoma floridae
TI:7739 None
   
A0A9L0S3S8_HORSE
Ensembl»
0.0
RGP1 RGP1 homolog, RAB6A GEF complex partner 1 Equus caballus
TI:9796 None
   
A0A9R0IC09_SPIOL
euHCVdb»
0.0
LOC110786151 Arrestin C-terminal-like
domain-containing protein		 Spinacia oleracea
TI:3562 None
   
A0AAA9SZG5_BOVIN
Ensembl»
0.0
RGP1 RGP1 homolog, RAB6A GEF complex partner 1 Bos taurus
TI:9913 None 		     
A0ABI7X3M6_FELCA
Ensembl»
0.0
RGP1 RGP1 homolog, RAB6A GEF complex partner 1 Felis catus
TI:9685 None 		     
A0ABM2ZBQ2_GOSHI
euHCVdb»
0.0
LOC107937601 RAB6A-GEF complex partner protein 2-like Gossypium hirsutum
TI:3635 None 		     
A0ABM2ZVW4_GOSHI
euHCVdb»
0.0
LOC121215945 Uncharacterized protein isoform X1 Gossypium hirsutum
TI:3635 None 		     
F1NZ59_CHICK
Ensembl»
0.0
RGP1 RGP1 homolog, RAB6A GEF complex partner 1 Gallus gallus
TI:9031 None 		     
F6UX55_MONDO
Ensembl»
0.0
RGP1 RGP1 homolog, RAB6A GEF complex partner 1 Monodelphis domestica
TI:13616 None
   
F6Z3E2_ORNAN
Ensembl»
0.0
RGP1 RGP1 homolog, RAB6A GEF complex partner 1 Ornithorhynchus anatinus
TI:9258 None
   
H2LUD1_ORYLA
Ensembl»
0.0
RGP1 GP1 homolog, RAB6A GEF complex partner 1 Oryzias latipes
TI:8090 None
   
M1CN32_SOLTU
EnsemblPlants»
0.0
RAB6A-GEF complex partner protein 2 Solanum tuberosum
TI:4113 None
   
M1CN33_SOLTU
EnsemblPlants»
0.0
Uncharacterized protein Solanum tuberosum
TI:4113 None
   
M4DCM2_BRACM
EnsemblPlants»
0.0
RAB6A-GEF complex partner protein 2 Brassica campestris
TI:3711 None
   
M4DQN9_BRACM
EnsemblPlants»
0.0
RAB6A-GEF complex partner protein 2 Brassica campestris
TI:3711 None