Collated Gene Ontology terms

Biological process: hydrolase activity(2017, 2025) 3'-5'-RNA exonuclease activity(2024, 2025) nuclease activity(2025) exonuclease activity(2025)

Molecular function: rRNA processing2024, 2025 mitochondrial RNA metabolic process2024, 2025 mRNA processing2024, 2025 positive regulation of cellular respiration2020, 2025 locomotory exploration behavior2013

Cellular component: nucleus2009, 2013, 2018, 2020, 2025 cytoplasm2018, 2025 mitochondrion2013, 2017, 2020, 2021, 2024, 2025 nucleoplasm2018, 2024, 2025 nucleolus2024, 2025 mitochondrial matrix2024, 2025 cytosol2009, 2019 chromatin2020, 2025 plastid2019

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 4/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 40/39 
Archea: 0/8 
Bacteria: 1/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A3B6NQQ3_WHEAT
EnsemblPlants»
0.0
Metal-dependent protein hydrolase Triticum aestivum
TI:4565 None
   
A0A6I8NC53_ORNAN
Ensembl»
0.0
MYG1 exonuclease Ornithorhynchus anatinus
TI:9258 None 		     
A0A7M7PEJ2_STRPU
EnsemblMetazoa»
0.0
Uncharacterized protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A804N8S6_MAIZE
EnsemblPlants»
0.0
Bifunctional inhibitor/plant lipid transfer
protein/seed storage helical domain-containing protein		 Zea mays
TI:4577 None
   
F6ZCS4_CIOIN
Ensembl»
0.0
Uncharacterized protein Ciona intestinalis
TI:7719 None
 
H3G8C1_PHYRM
EnsemblProtists»
0.0
Metal-dependent protein hydrolase Phytophthora ramorum
TI:164328 None
 
M4EIA2_BRACM
EnsemblPlants»
0.0
Metal-dependent protein hydrolase Brassica campestris
TI:3711 None
   
W5ME83_LEPOC
Ensembl»
0.0
Myg1 exonuclease Lepisosteus oculatus
TI:7918 None
 
G7J863_MEDTR
EnsemblPlants»
0.0
11430807 Metal-dependent protein hydrolase Medicago truncatula
TI:3880 None
 
Q7QC19_ANOGA
EnsemblMetazoa»
0.0
1273554 AGAP002408-PA Anopheles gambiae
TI:7165 None
 
T1FUH9_HELRO
EnsemblMetazoa»
0.0
20212475 Metal-dependent protein hydrolase Helobdella robusta
TI:6412 None
 
A0A072UT21_MEDTR
EnsemblPlants»
0.0
25491572 Metal-dependent protein hydrolase Medicago truncatula
TI:3880 None
 
Q4WTK5_ASPFU
TubercuList»
0.0
AFUA_1G08980 UPF0160 domain protein MYG1, putative Aspergillus fumigatus
TI:746128 None
 
Q74ZQ3_EREGS
euHCVdb»
0.0
AGOS_AGR145C AGR145Cp Eremothecium gossypii
TI:33169 None
 
W1PSV3_AMBTC
euHCVdb»
0.0
AMTR_s00027p00217440 Metal-dependent protein hydrolase Amborella trichopoda
TI:13333 None
 
Q5B5K2_EMENI
TubercuList»
0.0
ANIA_04178 UPF0160 domain protein
MYG1, putative (AFU_orthologue AFUA_1G08980)		 Emericella nidulans
TI:162425 None
 
D6WP32_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_13284 UPF0160 protein-like Protein Tribolium castaneum
TI:7070 None
 
F4NWD6_BATDJ
neXtProt»
0.0
BATDEDRAFT_9327 Uncharacterized protein Batrachochytrium dendrobatidis
TI:109871 None
 
M4DSU8_BRACM
EnsemblPlants»
0.0
BRAA06T25759Z Metal-dependent protein hydrolase Brassica campestris
TI:3711 None
 
A0A078I3S1_BRANA
euHCVdb»
0.0
BnaA06g23090D (rape) hypothetical
protein (BnaA06g23090D protein)		 Brassica napus
TI:3708 None
 
A0A078FG25_BRANA
euHCVdb»
0.0
BnaC06g13820D BnaC06g13820D protein Brassica napus
TI:3708 None
 
A0A078JDM7_BRANA
euHCVdb»
0.0
BnaCnng44010D BnaCnng44010D protein Brassica napus
TI:3708 None
 
A0A8V0ZZL9_CHICK
Ensembl»
0.0
C12orf10 MYG1 exonuclease Gallus gallus
TI:9031 None
   
YK4P_CAEEL
WormBase»
0.0
C27H6.8 K08H10.8 MYG1 protein C27H6.8 Caenorhabditis elegans
TI:6239 None
 
A0A1D8PCL4_CANAL
CGD»
0.0
CAALFM_C101910WA orf19.12007 Uncharacterized protein Candida albicans
TI:5476 None
 
A8XVL0_CAEBR
WormBase»
0.0
CBG19425 CBG_19425 Protein CBG19425 Caenorhabditis briggsae
TI:6238 None
 
A0A2K3E3H5_CHLRE
neXtProt»
0.0
CHLRE_02g118900v5 Metal-dependent protein hydrolase Chlamydomonas reinhardtii
TI:3055 None
 
A0A067GDK3_CITSI
neXtProt»
0.0
CISIN_1g019180mg Uncharacterized protein Citrus sinensis
TI:2711 None
 
Q5KI89_CRYD1
TubercuList»
0.0
CND03800 GAMM1 protein, putative Cryptococcus deneoformans
TI:40410 None
 
Y386_CHLTR
EnsemblBacteria»
0.0
CT_386 MYG1 protein CT_386 Chlamydia trachomatis
TI:813 None 		 
 
A0A0A0KMA5_CUCSA
euHCVdb»
0.0
Csa_5G148600 Protein MYG1 Cucumis sativus
TI:3659 None
 
E9H8Q2_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_308656 Uncharacterized protein Daphnia pulex
TI:6669 None
 
U160_DICDI
dictyBase»
0.0
DDB_G0267768 MYG1 protein Dictyostelium discoideum
TI:44689 None
 
F1A611_DICPU
TubercuList»
0.0
DICPUDRAFT_44326 Metal-dependent protein hydrolase Dictyostelium purpureum
TI:5786 None
 
Q8INP9_DROME
FlyBase»
2.0
Dmel\CG11980 RE51612p (Uncharacterized protein, isoform C) Drosophila melanogaster
TI:7227 None
 
C4LTJ8_ENTH1
TubercuList»
0.0
EHI_012050 Melanocyte prolifeating gene 1, putative Entamoeba histolytica
TI:5759 None
 
C4LXX9_ENTH1
TubercuList»
0.0
EHI_035480 Uncharacterized protein Entamoeba histolytica
TI:5759 None
 
C4M8X2_ENTH1
TubercuList»
0.0
EHI_120610 Metal dependent hydrolase, putative Entamoeba histolytica
TI:5759 None
 
C4M592_ENTH1
TubercuList»
0.0
EHI_154280 Uncharacterized protein Entamoeba histolytica
TI:5759 None
 
A0A058ZRY3_EUCGR
neXtProt»
0.0
EUGRSUZ_L02390 Uncharacterized protein Eucalyptus grandis
TI:71139 None
 
A8B787_GIAIC
TubercuList»
0.0
GL50803_0010858 MYG1 protein Giardia intestinalis
TI:5741 None
 
A0A0R0KFI8_SOYBN
EnsemblPlants»
0.0
GLYMA_03G068700 Metal-dependent protein hydrolase Glycine max
TI:3847 None
 
A0A804IW21_MUSAM
EnsemblPlants»
0.0
GSMUA_137370.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0A804I2H3_MUSAM
EnsemblPlants»
0.0
GSMUA_68700.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0DX97_PARTE
euHCVdb»
0.0
GSPATT00021296001 Metal-dependent protein hydrolase Paramecium tetraurelia
TI:5888 None
 
A0A251UG35_HELAN
neXtProt»
0.0
HannXRQ_Chr06g0166851 HanXRQr2_Chr06g0242041 Metal-dependent protein hydrolase Helianthus annuus
TI:4232 None
 
A0A251UHI1_HELAN
neXtProt»
0.0
HannXRQ_Chr06g0175641 HanXRQr2_Chr08g0339881 Metal-dependent protein hydrolase Helianthus annuus
TI:4232 None
 
A0A251RQ57_HELAN
neXtProt»
0.0
HannXRQ_Chr17g0534771 HanXRQr2_Chr17g0780271 Metal-dependent protein hydrolase Helianthus annuus
TI:4232 None
 
B7QBX3_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW012565 Secreted protein, putative Ixodes scapularis
TI:6945 None
 
A0A7U2FAS8_PHANO
TubercuList»
0.0
JI435_048440 Metal-dependent protein hydrolase Phaeosphaeria nodorum
TI:13684 None 		 
 
A0A1Y1HU53_KLENI
euHCVdb»
0.0
KFL_000290280 Metal-dependent protein hydrolase Klebsormidium nitens
TI:105231 None
 
Q4QHU0_LEIMA
TubercuList»
0.0
LMJF_09_0840 Metal-dependent protein hydrolase Leishmania major
TI:5664 None
 
B4FTN5_MAIZE
EnsemblPlants»
0.0
LOC100273215 Metal-dependent protein hydrolase Zea mays
TI:4577 None
 
I1JYM3_SOYBN
EnsemblPlants»
0.0
LOC100798858 Uncharacterized protein Glycine max
TI:3847 None
 
C6TAG0_SOYBN
EnsemblPlants»
0.0
LOC100800706 Metal-dependent protein hydrolase Glycine max
TI:3847 None
 
I1ICQ6_BRADI
EnsemblPlants»
0.0
LOC100826446 Metal-dependent protein hydrolase Brachypodium distachyon
TI:15368 None
 
A0A3Q7ITY0_SOLLC
EnsemblPlants»
0.0
LOC101254260 Uncharacterized protein Solanum lycopersicum
TI:4081 None
   
K3YT93_SETIT
EnsemblPlants»
0.0
LOC101771528 Metal-dependent protein hydrolase Setaria italica
TI:4555 None
 
K3ZU54_SETIT
EnsemblPlants»
0.0
LOC101773726 Metal-dependent protein hydrolase Setaria italica
TI:4555 None
 
M1AJA2_SOLTU
EnsemblPlants»
0.0
LOC102600259 Protein MYG1 Solanum tuberosum
TI:4113 None
   
A0A1U7ZFH1_NELNU
euHCVdb»
0.0
LOC104594040 UPF0160 protein C694.04c Nelumbo nucifera
TI:4432 None
   
A0A1S3YCE9_TOBAC
euHCVdb»
0.0
LOC107774698 UPF0160 protein
(Uncharacterized protein LOC107774698)		 Nicotiana tabacum
TI:4097 None
   
A0A1S4ARY0_TOBAC
euHCVdb»
0.0
LOC107800730 Uncharacterized protein LOC107800730 Nicotiana tabacum
TI:4097 None
   
A0A1U8HXJ0_GOSHI
euHCVdb»
0.0
LOC107890719 MYG1 protein Gossypium hirsutum
TI:3635 None
   
A0A1U8LVA0_GOSHI
euHCVdb»
0.0
LOC107930260 MYG1 exonuclease isoform X1 (UPF0160
protein MYG1, mitochondrial-like isoform X1)		 Gossypium hirsutum
TI:3635 None
   
A0A1U8NDV7_GOSHI
neXtProt»
0.0
LOC107947153 MYG1 protein Gossypium hirsutum
TI:3635 None
   
A0A1U8NE04_GOSHI
euHCVdb»
0.0
LOC107947166 MYG1 protein isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A2I4EY71_JUGRE
euHCVdb»
0.0
LOC108993775 MYG1 protein Juglans regia
TI:51240 None
   
A0A9R0I5P1_SPIOL
euHCVdb»
0.0
LOC110783154 Metal-dependent protein hydrolase Spinacia oleracea
TI:3562 None
   
A0A9R0J7Q9_SPIOL
neXtProt»
0.0
LOC110801691 Metal-dependent protein hydrolase Spinacia oleracea
TI:3562 None
   
A0A2K1JJ07_PHYPA
EnsemblPlants»
0.0
LOC112291109 Metal-dependent protein hydrolase Physcomitrium patens
TI:3218 None
 
A0A2K1J5A1_PHYPA
EnsemblPlants»
0.0
LOC112294542 Metal-dependent protein hydrolase Physcomitrium patens
TI:3218 None
 
A0A9J7LEV2_BRAFL
euHCVdb»
0.0
LOC118419327 MYG1 exonuclease-like Branchiostoma floridae
TI:7739 None
   
A0A9J7LH38_BRAFL
euHCVdb»
0.0
LOC118419329 MYG1 exonuclease-like Branchiostoma floridae
TI:7739 None
   
A0A3B6PM66_WHEAT
EnsemblPlants»
0.0
LOC123137808 Metal-dependent protein hydrolase Triticum aestivum
TI:4565 None
   
A0A3B6QGD7_WHEAT
EnsemblPlants»
0.0
LOC123145126 Metal-dependent protein hydrolase Triticum aestivum
TI:4565 None
   
A0A8I6Z2Q4_HORVV
EnsemblPlants»
0.0
LOC123400954 Metal-dependent protein hydrolase Hordeum vulgare
TI:4513 None 		     
A0A9R1WAU9_LACSA
neXtProt»
0.0
LSAT_V11C300106430 Metal-dependent protein hydrolase Lactuca sativa
TI:4236 None
 
A0A9R1UMH6_LACSA
euHCVdb»
0.0
LSAT_V11C800390480 Metal-dependent protein hydrolase Lactuca sativa
TI:4236 None
 
A0A2C9WB60_MANES
euHCVdb»
0.0
MANES_02G003700v8 Metal-dependent protein hydrolase Manihot esculenta
TI:3983 None
 
A0A2R6XVY5_MARPO
euHCVdb»
0.0
MARPO_0001s0278 Metal-dependent protein hydrolase Marchantia polymorpha
TI:3197 None
 
A0A022RL09_ERYGU
euHCVdb»
0.0
MIMGU_mgv1a008601mg Metal-dependent protein hydrolase Erythranthe guttata
TI:4155 None
 
F4K000_ARATH
TAIR»
0.0
MJC20.7 Metal-dependent protein hydrolase Arabidopsis thaliana
TI:3702 None
 
A9UV55_MONBE
euHCVdb»
0.0
MONBRDRAFT_20236 MYG1 protein Monosiga brevicollis
TI:81824 None
 
A0A072TR35_MEDTR
EnsemblPlants»
0.0
MTR_0373s0010 Metal-dependent protein hydrolase Medicago truncatula
TI:3880 None
 
A0A287A0Y1_PIG
Ensembl»
0.0
MYG1 MYG1 exonuclease Sus scrofa
TI:9823 None
   
A0A3Q2HYW2_HORSE
Ensembl»
0.0
MYG1 MYG1 exonuclease Equus caballus
TI:9796 None
   
A0A8I3PIY9_CANLF
Ensembl»
0.0
MYG1 MYG1 exonuclease Canis lupus
TI:9612 None 		     
A0AAF6Z7P4_BOVIN
Ensembl»
0.0
MYG1 MYG1 exonuclease Bos taurus
TI:9913 None
   
A0ABI7Z8Z2_FELCA
Ensembl»
0.0
MYG1 MYG1 exonuclease Felis catus
TI:9685 None 		     
F7HT82_MACMU
Ensembl»
0.0
MYG1 MYG1 exonuclease Macaca mulatta
TI:9544 None
   
G3RIA9_GORGO
Ensembl»
0.0
MYG1 MYG1 exonuclease Gorilla gorilla
TI:9593 None
 
H2LKA5_ORYLA
Ensembl»
0.0
MYG1 Myg1 exonuclease Oryzias latipes
TI:8090 None
   
H2Q620_PANTR
Ensembl»
0.0
MYG1 Chromosome 12 open reading
frame 10 (MYG1 exonuclease)		 Pan troglodytes
TI:9598 None
 
MYG1_BOVIN
TubercuList»
0.0
MYG1 MYG1 exonuclease (EC 3.1.-.-) Bos taurus
TI:9913 None
 
MYG1_HUMAN
Ensembl»
3.2
MYG1 MYG1 exonuclease (EC 3.1.-.-) Homo sapiens
TI:9606 None
 
MYG1_MOUSE
Ensembl»
2.8
Myg1 MYG1 exonuclease (EC 3.1.-.-) (Protein Gamm1) Mus musculus
TI:10090 None
 
MYG1_RAT
RGD»
2.5
Myg1 MYG1 exonuclease (EC 3.1.-.-) Rattus norvegicus
TI:10116 None
 
Q7RW75_NEUCR
TubercuList»
0.0
NCU03859 MYG1 protein Neurospora crassa
TI:5141 None
 
A7S559_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g105041 Uncharacterized protein Nematostella vectensis
TI:45351 None
 
A7S558_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g206968 Uncharacterized protein Nematostella vectensis
TI:45351 None
 
Q0DYK2_ORYSJ
euHCVdb»
0.0
Os02g0686600 Os02g0686600 protein Oryza sativa
TI:4530 None
 
C6KTA3_PLAF7
TubercuList»
0.0
PF3D7_0626700 ATPase Plasmodium falciparum
TI:5833 None
 
E3JR32_PUCGT
TubercuList»
0.0
PGTG_00386 Urease accessory protein Puccinia graminis
TI:5297 None
 
B9GY25_POPTR
euHCVdb»
0.0
POPTR_003G145900 Metal-dependent protein hydrolase Populus trichocarpa
TI:3694 None
 
B9IDL1_POPTR
euHCVdb»
0.0
POPTR_015G008200v4 Metal-dependent protein hydrolase Populus trichocarpa
TI:3694 None
 
M5X003_PRUPE
euHCVdb»
0.0
PRUPE_5G128600 Metal-dependent protein hydrolase Prunus persica
TI:3760 None
 
B9RYS8_RICCO
neXtProt»
0.0
RCOM_1313110 Protein MYG1, putative Ricinus communis
TI:3988 None
 
B9TKT4_RICCO
neXtProt»
0.0
RCOM_1819890 Protein MYG1, putative Ricinus communis
TI:3988 None
 
D8T277_SELML
euHCVdb»
0.0
SELMODRAFT_229483 Uncharacterized protein Selaginella moellendorffii
TI:88036 None
 
D8T869_SELML
euHCVdb»
0.0
SELMODRAFT_272231 Uncharacterized protein Selaginella moellendorffii
TI:88036 None
 
B6JY42_SCHJY
TubercuList»
0.0
SJAG_01501 Eukaryotic protein Schizosaccharomyces japonicus
TI:4897 None
 
C5Y0V5_SORBI
neXtProt»
0.0
SORBI_3004G278500 Metal-dependent protein hydrolase Sorghum bicolor
TI:4558 None
 
YIW4_SCHPO
PomBase»
0.5
SPAC694.04c MYG1 protein C694.04c Schizosaccharomyces pombe
TI:4896 None
 
A7EYZ0_SCLS1
TubercuList»
0.0
SS1G_10556 MYG1 protein Sclerotinia sclerotiorum
TI:5180 None
 
Q9SG17_ARATH
TAIR»
0.0
T1G12.2 Metal-dependent protein hydrolase Arabidopsis thaliana
TI:3702 None
 
A0A1U8GMC4_CAPAN
neXtProt»
0.0
T459_12044 UPF0160 protein MYG1, mitochondrial Capsicum annuum
TI:4072 None
 
A0A061G273_THECC
euHCVdb»
0.0
TCM_015474 Metal-dependent protein hydrolase isoform 1 Theobroma cacao
TI:3641 None
 
A0A061G3C9_THECC
euHCVdb»
0.0
TCM_015663 Metal-dependent protein hydrolase Theobroma cacao
TI:3641 None
 
B8CEM1_THAPS
neXtProt»
0.0
THAPSDRAFT_832 Uncharacterized protein Thalassiosira pseudonana
TI:35128 None
 
B3RLS8_TRIAD
CTD»
0.0
TRIADDRAFT_52107 Uncharacterized protein Trichoplax adhaerens
TI:10228 None
 
A2EHD7_TRIV3
TubercuList»
0.0
TVAG_064620 Metal-dependent protein hydrolase Trichomonas vaginalis
TI:5722 None
 
A2ENX4_TRIV3
TubercuList»
0.0
TVAG_216400 Uncharacterized protein Trichomonas vaginalis
TI:5722 None
 
A2FXE9_TRIV3
TubercuList»
0.0
TVAG_488660 Metal-dependent protein hydrolase Trichomonas vaginalis
TI:5722 None
 
Q382P1_TRYB2
TubercuList»
0.0
Tb11.52.0013 Metal binding protein Trypanosoma brucei
TI:5691 None
 
D7TVP9_VITVI
euHCVdb»
0.0
VIT_02s0025g02440 Uncharacterized protein Vitis vinifera
TI:29760 None
 
A0A2A6CRK9_PRIPA
EnsemblMetazoa»
0.0
WBGene00276098 Uncharacterized protein Pristionchus pacificus
TI:54126 None
   
Q6C7V8_YARLI
TubercuList»
0.0
YALI0_D24970g YALI0D24970p Yarrowia lipolytica
TI:4952 None
 
YEY6_YEAST
SGD»
0.8
YER156C MYG1 protein YER156C Saccharomyces cerevisiae
TI:4932 None
 
A0A0K9PXA2_ZOSMR
neXtProt»
0.0
ZOSMA_146G00450 Uncharacterized protein Zostera marina
TI:29655 None
 
A0A0K9PBV0_ZOSMR
euHCVdb»
0.0
ZOSMA_313G00100 Metal-dependent protein hydrolase Zostera marina
TI:29655 None
 
A0A0K9NXV4_ZOSMR
neXtProt»
0.0
ZOSMA_513G00060 Uncharacterized protein Zostera marina
TI:29655 None
 
A0A140LG01_DANRE
ZFIN»
0.0
myg1 Myg1 exonuclease (UPF0160
protein MYG1, mitochondrial)		 Danio rerio
TI:7955 None
 
F6VXZ9_XENTR
Xenbase»
0.0
myg1 MYG1 exonuclease (Melanocyte proliferating gene
1) (UPF0160 protein MYG1, mitochondrial)		 Xenopus tropicalis
TI:8364 None
 
H9GA94_ANOCA
Ensembl»
0.0
myg1 Uncharacterized protein Anolis carolinensis
TI:28377 None
   
Q3KPM3_XENLA
Xenbase»
0.0
myg1.S LOC496075 protein
(Uncharacterized protein LOC496075)		 Xenopus laevis
TI:8355 None