Collated Gene Ontology terms

Biological process: nuclease activity(2025) hydrolase activity, acting on ester bonds(2025) hydrolase activity(2025) metal ion binding(2014, 2025) 3'-5'-DNA exonuclease activity(2015, 2025) DNA endonuclease activity(2025) exonuclease activity(2025) endonuclease activity(2015, 2025) DNA nuclease activity(2006, 2007, 2009, 2014, 2025) single-stranded DNA 3'-5' DNA exonuclease activity(2014, 2025)
DNA-binding transcription factor activity2025 3'-5'-RNA exonuclease activity2014, 2025 magnesium ion binding2025 3'-5' exonuclease activity2025 deoxyribonuclease I activity2015

Molecular function: DNA metabolic process2007, 2025 apoptotic DNA fragmentation2006, 2013, 2025 cellular response to oxidative stress2013, 2025 regulation of DNA-templated transcription2025 apoptotic cell clearance2006, 2025 retina layer formation2015 response to hydrogen peroxide2014 response to bacterium2020 innate immune response2014 eye development2015
DNA replication2015 DNA catabolic process2007

Cellular component: nucleus2009, 2018, 2025 cytoplasm2008, 2017, 2018, 2025 nucleoplasm2024, 2025 cytosol2009, 2014, 2025 nuclear lumen2017 ciliary plasm2017 mitochondrion2024 apicoplast2015

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 3/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 6/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A8I6AHP3_RAT
RGD»
1.5
Tatdn1 Deoxyribonuclease TATDN1 Rattus norvegicus
TI:10116 None
   
A0A8V0Y0W3_CHICK
Ensembl»
0.5
TATDN1 Deoxyribonuclease TATDN1 Gallus gallus
TI:9031 None
   
G5EG18_CAEEL
WormBase»
3.7
crn-2 Deoxyribonuclease TATDN1 Caenorhabditis elegans
TI:6239 None
 
Q54KD6_DICDI
dictyBase»
0.0
DDB_G0287397 TatD-related deoxyribonuclease Dictyostelium discoideum
TI:44689 None
 
Q54SD3_DICDI
dictyBase»
0.5
DDB_G0282531 Uncharacterized protein Dictyostelium discoideum
TI:44689 None
 
Q55DK1_DICDI
dictyBase»
0.5
DDB_G0269630 TatD-related DNAse Dictyostelium discoideum
TI:44689 None
 
Q7JUN9_DROME
FlyBase»
0.5
Dmel\CG3358 Deoxyribonuclease TATDN1 Drosophila melanogaster
TI:7227 None
 
Q84TD7_ARATH
TAIR»
0.0
At3g52390 At3g52390 (TatD related DNase) Arabidopsis thaliana
TI:3702 None
 
Q9VDC1_DROME
FlyBase»
0.0
Dmel\CG3308 Deoxyribonuclease TATDN1 Drosophila melanogaster
TI:7227 None
 
TATD1_DANRE
ZFIN»
3.7
tatdn1 Deoxyribonuclease TATDN1 (EC 3.1.11.-) (EC 3.1.21.-)
(DNA-(apurinic or apyrimidinic site) endonuclease TATDN1)		 Danio rerio
TI:7955 None
 
TATD1_HUMAN
Ensembl»
2.1
TATDN1 Deoxyribonuclease TATDN1 (EC 3.1.11.-) (EC 3.1.21.-) (DNA-(apurinic or
apyrimidinic site) endonuclease TATDN1) (Hepatocarcinoma high expression protein)		 Homo sapiens
TI:9606 None
 
TATD1_MOUSE
Ensembl»
2.5
Tatdn1 Deoxyribonuclease TATDN1 (EC 3.1.11.-) (EC 3.1.21.-)
(DNA-(apurinic or apyrimidinic site) endonuclease TATDN1)		 Mus musculus
TI:10090 None
 
TATD_ECOLI
EnsemblBacteria»
4.6
tatD 3'-5' ssDNA/RNA exonuclease TatD (EC
3.1.11.-) (EC 3.1.13.-) (DNase TatD)		 Escherichia coli
TI:562 None
 
YBF5_YEAST
SGD»
3.7
YBL055C Deoxyribonuclease Tat-D (EC 3.1.21.-) Saccharomyces cerevisiae
TI:4932 None
 
YNF8_SCHPO
PomBase»
1.5
pi038 SPBC17A3.08 Deoxyribonuclease Tat-D (EC 3.1.21.-) Schizosaccharomyces pombe
TI:4896 None