Collated Gene Ontology terms

Biological process: 4-coumarate-CoA ligase activity(2024) trans-cinnamate-CoA ligase activity(2024) nucleotide binding(2024) ligase activity(2024) ATP binding(2024) isomerase activity(2024) acid-thiol ligase activity(2008) protein serine/threonine kinase activity(2023, 2024) phenylalanine racemase (ATP-hydrolyzing) activity(2024) xyloglucan:xyloglucosyl transferase activity(2024)
transferase activity2024 protein kinase activity2024 oxidoreductase activity2024 kinase activity2024 hydrolase activity, hydrolyzing O-glycosyl compounds2024 hydrolase activity, acting on glycosyl bonds2024 glutamate racemase activity2024 beta-alanyl amine synthase activity2021

Molecular function: amino acid activation for nonribosomal peptide biosynthetic process2016, 2021, 2024 phenylpropanoid metabolic process2024 lipid metabolic process2024 beta-alanine metabolic process2016, 2024 fatty acid metabolic process2009, 2024 phosphorylation2024 xyloglucan metabolic process2024 protein phosphorylation2024 cell wall biogenesis2024 carboxylic acid metabolic process2024

Cellular component: membrane2024 cytoplasm2024 apoplast2024

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 2/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 36/39 
Archea: 0/8 
Bacteria: 3/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A022Q952_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a0196451mg AMP-dependent synthetase/ligase
domain-containing protein		 Erythranthe guttata
TI:4155 None
 
A0A022QDB0_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a0196452mg Carrier domain-containing protein Erythranthe guttata
TI:4155 None
 
A0A022RP76_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a0007033mg Carrier domain-containing protein Erythranthe guttata
TI:4155 None 		 
 
A0A022RQF8_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a0007031mg AMP-dependent synthetase/ligase
domain-containing protein		 Erythranthe guttata
TI:4155 None
 
A0A022RQK5_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a0007032mg Uncharacterized protein Erythranthe guttata
TI:4155 None 		 
 
A0A061F726_THECC
EnsemblPlants»
0.0
TCM_025682 AMP-dependent synthetase and ligase
family protein, putative isoform 1		 Theobroma cacao
TI:3641 None
 
A0A067DIB7_CITSI
Ensembl»
0.0
CISIN_1g0026152mg Carrier domain-containing protein Citrus sinensis
TI:2711 None
 
A0A078HT76_BRANA
EnsemblPlants»
0.0
BnaA08g07100D BnaA08g07100D protein Brassica napus
TI:3708 None
 
A0A078JIS2_BRANA
EnsemblPlants»
0.0
BnaCnng48170D BnaCnng48170D protein Brassica napus
TI:3708 None
 
A0A0A0LHL5_CUCSA
EnsemblPlants»
0.0
Csa_2G120255 Cleavage/polyadenylation specificity factor A
subunit N-terminal domain-containing protein		 Cucumis sativus
TI:3659 None 		 
 
A0A0A0LI04_CUCSA
EnsemblPlants»
0.0
Csa_2G120005 AMP-dependent synthetase/ligase
domain-containing protein		 Cucumis sativus
TI:3659 None 		 
 
A0A0A0LK33_CUCSA
EnsemblPlants»
0.0
Csa_2G120130 Carrier domain-containing protein Cucumis sativus
TI:3659 None 		 
 
A0A0K9NQ15_ZOSMR
EnsemblPlants»
0.0
ZOSMA_7G01840 Acyl-activating enzyme 19 Zostera marina
TI:29655 None 		 
 
A0A0K9PE29_ZOSMR
EnsemblPlants»
0.0
ZOSMA_29G01660 4-coumarate--CoA ligase (EC 6.2.1.12) Zostera marina
TI:29655 None
 
A0A0P0WS15_ORYSJ
EnsemblPlants»
0.0
Os06g0111600 4-coumarate--CoA ligase (EC 6.2.1.12) Oryza sativa
TI:4530 None
 
A0A0Q3JPT6_BRADI
EnsemblPlants»
0.0
100832101 4-coumarate--CoA ligase (EC 6.2.1.12) Brachypodium distachyon
TI:15368 None
 
A0A0U9HI43_KLENI
EnsemblPlants»
0.0
KFL_000060600 Carrier domain-containing protein Klebsormidium nitens
TI:105231 None
 
A0A1D6NWQ9_MAIZE
EnsemblPlants»
0.0
103638170 4-coumarate--CoA ligase (EC 6.2.1.12) Zea mays
TI:4577 None
 
A0A1L8HTW3_XENLA
Xenbase»
0.0
aasdh.L Beta-alanine-activating enzyme Xenopus laevis
TI:8355 None
   
A0A1S3X4E2_TOBAC
EnsemblFungi»
0.0
LOC107760944 Acyl-activating enzyme 19 isoform X1 Nicotiana tabacum
TI:4097 None
   
A0A1S4BEJ9_TOBAC
EnsemblFungi»
0.0
LOC107807467 Acyl-activating enzyme 19 isoform X1 Nicotiana tabacum
TI:4097 None
   
A0A1S4H2U4_ANOGA
EnsemblMetazoa»
0.0
AMP-dependent synthetase/ligase
domain-containing protein		 Anopheles gambiae
TI:7165 None
 
A0A1U8AKG4_NELNU
EnsemblBacteria»
0.0
LOC104605230 Acyl-activating enzyme 19 isoform X1 Nelumbo nucifera
TI:4432 None
 
A0A1U8KR30_GOSHI
Ensembl»
0.0
LOC107919976 Acyl-activating enzyme 19 isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A1U8PUF7_GOSHI
Ensembl»
0.0
LOC107962164 Acyl-activating enzyme 19 isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A1W0VR07_SORBI
EnsemblPlants»
0.0
SORBI_3010G009200 Carrier domain-containing protein Sorghum bicolor
TI:4558 None
 
A0A251QDM3_PRUPE
EnsemblPlants»
0.0
PRUPE_2G098200 Carrier domain-containing protein Prunus persica
TI:3760 None
 
A0A251VQF5_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr01g0020521 Putative AMP-dependent synthetase
and ligase family protein		 Helianthus annuus
TI:4232 None
 
A0A287ABP0_PIG
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Sus scrofa
TI:9823 None
   
A0A2A6BQ49_PRIPA
EnsemblMetazoa»
0.0
WBGene00114305 AMP-binding protein Pristionchus pacificus
TI:54126 None 		 
 
A0A2C9VAE5_MANES
EnsemblPlants»
0.0
MANES_09G131500 Carrier domain-containing protein Manihot esculenta
TI:3983 None
 
A0A2G3ALX6_CAPAN
EnsemblPlants»
0.0
T459_03114 Uncharacterized protein Capsicum annuum
TI:4072 None
 
A0A2K1WPH6_POPTR
EnsemblPlants»
0.0
POPTR_019G043800 Carrier domain-containing protein Populus trichocarpa
TI:3694 None
 
A0A2K3D4P9_CHLRE
EnsemblPlants»
0.0
CHLRE_12g529301v5 AMP-dependent synthetase/ligase
domain-containing protein		 Chlamydomonas reinhardtii
TI:3055 None
 
A0A3B6H1R0_WHEAT
EnsemblPlants»
0.0
4-coumarate--CoA ligase (EC 6.2.1.12) Triticum aestivum
TI:4565 None
   
A0A3B6R792_WHEAT
EnsemblPlants»
0.0
CFC21_095292 4-coumarate--CoA ligase (EC 6.2.1.12) Triticum aestivum
TI:4565 None
 
A0A3B6RA89_WHEAT
EnsemblPlants»
0.0
CFC21_095048 4-coumarate--CoA ligase (EC 6.2.1.12) Triticum aestivum
TI:4565 None
 
A0A3B6SKX7_WHEAT
EnsemblPlants»
0.0
CFC21_105696 4-coumarate--CoA ligase (EC 6.2.1.12) Triticum aestivum
TI:4565 None
 
A0A3B6T7W6_WHEAT
EnsemblPlants»
0.0
CFC21_106646 4-coumarate--CoA ligase (EC 6.2.1.12) Triticum aestivum
TI:4565 None
 
A0A3Q1NC05_BOVIN
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Bos taurus
TI:9913 None
   
A0A3Q2KZL1_HORSE
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Equus caballus
TI:9796 None
   
A0A3Q7F1X0_SOLLC
EnsemblPlants»
0.0
xyloglucan:xyloglucosyl transferase
(EC 2.4.1.207)		 Solanum lycopersicum
TI:4081 None
   
A0A5F8A4V3_MACMU
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Macaca mulatta
TI:9544 None
   
A0A6I8Q471_XENTR
Xenbase»
0.0
aasdh Aminoadipate-semialdehyde dehydrogenase (Beta-alanine-activating
enzyme isoform X1)		 Xenopus tropicalis
TI:8364 None
   
A0A6P9EL02_JUGRE
EnsemblPlants»
0.0
LOC109018657 Acyl-activating enzyme 19 isoform X1 Juglans regia
TI:51240 None
 
A0A7I4ABU9_PHYPA
EnsemblPlants»
0.0
Carrier domain-containing protein Physcomitrium patens
TI:3218 None
 
A0A7M7NG43_STRPU
EnsemblMetazoa»
0.0
Carrier domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7NK29_STRPU
EnsemblMetazoa»
0.0
Carrier domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A804HVM6_MUSAM
EnsemblPlants»
0.0
GSMUA_302110.1 4-coumarate--CoA ligase (EC 6.2.1.12) Musa acuminata
TI:4641 None
 
A0A8I3P014_CANLF
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Canis lupus
TI:9612 None
   
A0A8I7BD00_HORVV
EnsemblPlants»
0.0
4-coumarate--CoA ligase (EC 6.2.1.12) Hordeum vulgare
TI:4513 None
   
A0A8V0YIR5_CHICK
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Gallus gallus
TI:9031 None
   
A0A9J7LEW7_BRAFL
CTD»
0.0
LOC118419340 Beta-alanine-activating enzyme-like Branchiostoma floridae
TI:7739 None 		     
A0A9J7MAZ8_BRAFL
CTD»
0.0
LOC118430475 Uncharacterized protein YxaL-like Branchiostoma floridae
TI:7739 None 		     
A0A9J7MSF9_BRAFL
CTD»
0.0
LOC118416496 Uncharacterized protein LOC118416496 Branchiostoma floridae
TI:7739 None 		     
A0A9K3JW32_HELAN
EnsemblPlants»
0.0
HanXRQr2_Chr01g0027761 Quinoprotein alcohol
dehydrogenase-like superfamily		 Helianthus annuus
TI:4232 None 		 
 
A7RVL7_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g95034 AMP-dependent synthetase/ligase
domain-containing protein		 Nematostella vectensis
TI:45351 None
 
A7TCQ0_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g225329 Uncharacterized protein Nematostella vectensis
TI:45351 None 		 
 
A8XH78_CAEBR
WormBase»
0.0
CBG13167 CBG_13167 Protein CBG13167 Caenorhabditis briggsae
TI:6238 None
 
A9V587_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_10108 AMP-dependent synthetase/ligase
domain-containing protein		 Monosiga brevicollis
TI:81824 None
 
A9WCN3_CHLAA
EnsemblBacteria»
0.0
Caur_3817 Protein kinase Chloroflexus aurantiacus
TI:1108 None
 
ACSF4_DANRE
ZFIN»
1.5
aasdh Beta-alanine-activating enzyme (EC 6.2.1.-)
(Acyl-CoA synthetase family member 4)		 Danio rerio
TI:7955 None
 
ACSF4_DROME
FlyBase»
1.5
Aasdh Beta-alanine-activating enzyme (EC 6.2.1.-)
(Acyl-CoA synthetase family member 4)		 Drosophila melanogaster
TI:7227 None
 
ACSF4_HUMAN
Ensembl»
1.0
AASDH Beta-alanine-activating enzyme (EC 6.2.1.-) (Acyl-CoA
synthetase family member 4) (Protein NRPS998)		 Homo sapiens
TI:9606 None
 
ACSF4_MOUSE
Ensembl»
2.6
Aasdh Beta-alanine-activating enzyme (EC 6.2.1.-) (Acyl-CoA synthetase
family member 4) (Protein LYS2 homolog)		 Mus musculus
TI:10090 None
 
AEE19_ARATH
TAIR»
0.0
At5g35930 Putative acyl-activating enzyme 19 Arabidopsis thaliana
TI:3702 None 		 
 
B3RXV2_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_56341 AMP-dependent synthetase/ligase
domain-containing protein		 Trichoplax adhaerens
TI:10228 None
 
B6VQ94_CAEEL
WormBase»
0.5
CELE_W09D6.1 W09D6.1 AMP-dependent synthetase/ligase
domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
B7PZD5_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW010234 AMP dependent ligase, putative (EC
5.1.1.3) (AMP dependent ligase, putative (Fragment))		 Ixodes scapularis
TI:6945 None
 
B7Q793_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW011488 Peptide synthetase, putative (EC
5.1.1.11) (Peptide synthetase, putative (Fragment))		 Ixodes scapularis
TI:6945 None
 
B9SDD9_RICCO
EnsemblBacteria»
0.0
RCOM_1516860 AMP dependent ligase, putative (EC 5.1.1.11) Ricinus communis
TI:3988 None
 
D1ZZ87_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_08000 Luciferin 4-monooxygenase (EC 1.13.12.7) Tribolium castaneum
TI:7070 None
 
D4A5F5_RAT
RGD»
1.5
Aasdh Aminoadipate-semialdehyde dehydrogenase Rattus norvegicus
TI:10116 None
   
D8RRG7_SELML
EnsemblPlants»
0.0
SELMODRAFT_149203 Carrier domain-containing protein Selaginella moellendorffii
TI:88036 None
 
D8RXC6_SELML
EnsemblPlants»
0.0
SELMODRAFT_103915 Carrier domain-containing protein Selaginella moellendorffii
TI:88036 None
 
DRRP_DEIRA
EnsemblBacteria»
0.0
DR_1769 Desiccation/radiation resistance protein DR_1769 Deinococcus radiodurans
TI:1299 None 		 
 
E9HCL2_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_328037 Carrier domain-containing protein Daphnia pulex
TI:6669 None
 
F4P6D7_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_89663 Uncharacterized protein Batrachochytrium dendrobatidis
TI:109871 None 		 
 
F4P6D8_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_26038 AMP-dependent synthetase/ligase
domain-containing protein		 Batrachochytrium dendrobatidis
TI:109871 None 		 
 
F6I1S6_VITVI
EnsemblPlants»
0.0
VIT_15s0107g00450 AMP-dependent synthetase/ligase
domain-containing protein		 Vitis vinifera
TI:29760 None 		 
 
F6I1S7_VITVI
EnsemblPlants»
0.0
VIT_15s0107g00470 Acyl-activating enzyme 19 Vitis vinifera
TI:29760 None 		 
 
F6I1S8_VITVI
EnsemblPlants»
0.0
VIT_15s0107g00500 Acyl-activating enzyme 19 Vitis vinifera
TI:29760 None 		 
 
F6S2A1_CIOIN
Ensembl»
0.0
AMP-dependent synthetase/ligase
domain-containing protein		 Ciona intestinalis
TI:7719 None
 
F6W7A3_ORNAN
Ensembl»
0.0
Carrier domain-containing protein Ornithorhynchus anatinus
TI:9258 None
   
F7DKF4_MONDO
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Monodelphis domestica
TI:13616 None
   
G1KIG6_ANOCA
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Anolis carolinensis
TI:28377 None
   
G3S7P1_GORGO
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Gorilla gorilla
TI:9593 None
 
G7LCR6_MEDTR
EnsemblPlants»
0.0
MTR_8g035620 AMP-dependent synthetase and
ligase family protein		 Medicago truncatula
TI:3880 None
 
H2L982_ORYLA
Ensembl»
0.0
aasdh Aminoadipate-semialdehyde dehydrogenase Oryzias latipes
TI:8090 None
   
K3XUX5_SETIT
EnsemblPlants»
0.0
4-coumarate--CoA ligase (EC 6.2.1.12) Setaria italica
TI:4555 None
 
K7C9C7_PANTR
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Pan troglodytes
TI:9598 None
 
K7KCC2_SOYBN
EnsemblPlants»
0.0
100820175 Carrier domain-containing protein Glycine max
TI:3847 None
 
M0ZNM7_SOLTU
EnsemblPlants»
0.0
AMP dependent ligase Solanum tuberosum
TI:4113 None 		       
M3W654_FELCA
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Felis catus
TI:9685 None
 
M4F374_BRACM
EnsemblPlants»
0.0
Carrier domain-containing protein Brassica campestris
TI:3711 None
   
Q7UKD4_RHOBA
EnsemblBacteria»
0.0
RB10706 Similar to serine/threonine protein
kinase related protein-putative PQQ-dependent oxidoreductase		 Rhodopirellula baltica
TI:265606 None
 
T1EZZ4_HELRO
EnsemblMetazoa»
0.0
20202144 AMP-dependent synthetase/ligase
domain-containing protein		 Helobdella robusta
TI:6412 None
 
U5CQT7_AMBTC
EnsemblPlants»
0.0
AMTR_s00048p00109480 Carrier domain-containing protein Amborella trichopoda
TI:13333 None
 
W5N9G5_LEPOC
Ensembl»
0.0
Aminoadipate-semialdehyde dehydrogenase Lepisosteus oculatus
TI:7918 None