Collated Gene Ontology terms

Biological process: 4-coumarate-CoA ligase activity(2023) trans-cinnamate-CoA ligase activity(2023) ligase activity(2023) nucleotide binding(2023) ATP binding(2023) isomerase activity(2023) acid-thiol ligase activity(2008) protein serine/threonine kinase activity(2023) phenylalanine racemase (ATP-hydrolyzing) activity(2023) kinase activity(2023)
xyloglucan:xyloglucosyl transferase activity2023 transferase activity2023 protein kinase activity2023 oxidoreductase activity2023 monooxygenase activity2023 hydrolase activity, hydrolyzing O-glycosyl compounds2023 hydrolase activity, acting on glycosyl bonds2023 hydrolase activity2023 glutamate racemase activity2023 beta-alanyl amine synthase activity2021

Molecular function: amino acid activation for nonribosomal peptide biosynthetic process2016, 2021, 2023 phenylpropanoid metabolic process2023 lipid metabolic process2023 beta-alanine metabolic process2016, 2023 organic substance metabolic process2023 fatty acid metabolic process2009, 2023 carboxylic acid metabolic process2023 organic substance biosynthetic process2023 phosphorylation2023 cellular biosynthetic process2023
xyloglucan metabolic process2023 primary metabolic process2023 metabolic process2023 glucan metabolic process2023 cell wall biogenesis2023 carbohydrate metabolic process2023 bioluminescence2023

Cellular component: peroxisome2023 membrane2023 cytoplasm2023 apoplast2023

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 2/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 36/39 
Archea: 0/8 
Bacteria: 3/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 0 2 4 6 8 10 Knownness

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
U5CQT7_AMBTC
EnsemblPlants»
0.0
AMTR_s00048p00109480 Carrier domain-containing protein Amborella trichopoda
TI:13333 None
 
G1KIG6_ANOCA
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Anolis carolinensis
TI:28377 None
   
A0A1S4H2U4_ANOGA
EnsemblMetazoa»
0.0
AMP-dependent synthetase/ligase
domain-containing protein		 Anopheles gambiae
TI:7165 None
 
AEE19_ARATH
TAIR»
0.0
At5g35930 Putative acyl-activating enzyme 19 Arabidopsis thaliana
TI:3702 None 		 
 
F4P6D7_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_89663 Uncharacterized protein Batrachochytrium dendrobatidis
TI:109871 None 		 
 
F4P6D8_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_26038 AMP-dependent synthetase/ligase
domain-containing protein		 Batrachochytrium dendrobatidis
TI:109871 None 		 
 
A0A3Q1NC05_BOVIN
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Bos taurus
TI:9913 None
   
A0A0Q3JPT6_BRADI
EnsemblPlants»
0.0
100832101 4-coumarate--CoA ligase (EC 6.2.1.12) Brachypodium distachyon
TI:15368 None
 
A0A9J7LEW7_BRAFL
CTD»
0.0
LOC118419340 Beta-alanine-activating enzyme-like Branchiostoma floridae
TI:7739 None 		     
A0A9J7MAZ8_BRAFL
CTD»
0.0
LOC118430475 Uncharacterized protein YxaL-like Branchiostoma floridae
TI:7739 None 		     
A0A9J7MSF9_BRAFL
CTD»
0.0
LOC118416496 Uncharacterized protein LOC118416496 Branchiostoma floridae
TI:7739 None 		     
A0A078HT76_BRANA
EnsemblPlants»
0.0
BnaA08g07100D BnaA08g07100D protein Brassica napus
TI:3708 None
 
A0A078JIS2_BRANA
EnsemblPlants»
0.0
BnaCnng48170D BnaCnng48170D protein Brassica napus
TI:3708 None
 
A8XH78_CAEBR
WormBase»
0.0
CBG13167 CBG_13167 Protein CBG13167 Caenorhabditis briggsae
TI:6238 None
 
B6VQ94_CAEEL
WormBase»
0.5
CELE_W09D6.1 W09D6.1 AMP-dependent synthetase/ligase
domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
A0A8I3P014_CANLF
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Canis lupus
TI:9612 None
   
A0A2G3ALX6_CAPAN
EnsemblPlants»
0.0
T459_03114 Uncharacterized protein Capsicum annuum
TI:4072 None
 
A0A2K3D4P9_CHLRE
EnsemblPlants»
0.0
CHLRE_12g529301v5 AMP-dependent synthetase/ligase
domain-containing protein		 Chlamydomonas reinhardtii
TI:3055 None
 
A9WCN3_CHLAA
EnsemblBacteria»
0.0
Caur_3817 Protein kinase Chloroflexus aurantiacus
TI:1108 None
 
F6S2A1_CIOIN
Ensembl»
0.0
AMP-dependent synthetase/ligase
domain-containing protein		 Ciona intestinalis
TI:7719 None
 
A0A067DIB7_CITSI
Ensembl»
0.0
CISIN_1g0026152mg Carrier domain-containing protein Citrus sinensis
TI:2711 None
 
A0A0A0LHL5_CUCSA
EnsemblPlants»
0.0
Csa_2G120255 Cleavage/polyadenylation specificity factor A
subunit N-terminal domain-containing protein		 Cucumis sativus
TI:3659 None 		 
 
A0A0A0LI04_CUCSA
EnsemblPlants»
0.0
Csa_2G120005 AMP-dependent synthetase/ligase
domain-containing protein		 Cucumis sativus
TI:3659 None 		 
 
A0A0A0LK33_CUCSA
EnsemblPlants»
0.0
Csa_2G120130 Carrier domain-containing protein Cucumis sativus
TI:3659 None 		 
 
ACSF4_DANRE
ZFIN»
1.5
aasdh Beta-alanine-activating enzyme (EC 6.2.1.-)
(Acyl-CoA synthetase family member 4)		 Danio rerio
TI:7955 None
 
E9HCL2_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_328037 Carrier domain-containing protein Daphnia pulex
TI:6669 None
 
DRRP_DEIRA
EnsemblBacteria»
0.0
DR_1769 Desiccation/radiation resistance protein DR_1769 Deinococcus radiodurans
TI:1299 None 		 
 
ACSF4_DROME
FlyBase»
1.5
Aasdh Beta-alanine-activating enzyme (EC 6.2.1.-)
(Acyl-CoA synthetase family member 4)		 Drosophila melanogaster
TI:7227 None
 
A0A3Q2KZL1_HORSE
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Equus caballus
TI:9796 None
   
A0A022Q952_ERYGU
Ensembl»
0.0
MIMGU_mgv1a0196451mg AMP-dependent synthetase/ligase
domain-containing protein		 Erythranthe guttata
TI:4155 None
 
A0A022QDB0_ERYGU
Ensembl»
0.0
MIMGU_mgv1a0196452mg Carrier domain-containing protein Erythranthe guttata
TI:4155 None
 
A0A022RP76_ERYGU
Ensembl»
0.0
MIMGU_mgv1a0007033mg Carrier domain-containing protein Erythranthe guttata
TI:4155 None 		 
 
A0A022RQF8_ERYGU
Ensembl»
0.0
MIMGU_mgv1a0007031mg AMP-dependent synthetase/ligase
domain-containing protein		 Erythranthe guttata
TI:4155 None
 
A0A022RQK5_ERYGU
Ensembl»
0.0
MIMGU_mgv1a0007032mg Uncharacterized protein Erythranthe guttata
TI:4155 None 		 
 
A0A059CEK4_EUCGR
EnsemblPlants»
0.0
EUGRSUZ_D01046 Carrier domain-containing protein Eucalyptus grandis
TI:71139 None 		 
 
M3W654_FELCA
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Felis catus
TI:9685 None
 
A0A8V0YIR5_CHICK
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Gallus gallus
TI:9031 None
   
K7KCC2_SOYBN
EnsemblPlants»
0.0
100820175 Carrier domain-containing protein Glycine max
TI:3847 None
 
G3S7P1_GORGO
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Gorilla gorilla
TI:9593 None
 
A0A1U8KR30_GOSHI
Ensembl»
0.0
LOC107919976 Acyl-activating enzyme 19 isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A1U8PUF7_GOSHI
Ensembl»
0.0
LOC107962164 Acyl-activating enzyme 19 isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A251VQF5_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr01g0020521 Putative AMP-dependent synthetase
and ligase family protein		 Helianthus annuus
TI:4232 None
 
A0A9K3JW32_HELAN
EnsemblPlants»
0.0
HanXRQr2_Chr01g0027761 Quinoprotein alcohol
dehydrogenase-like superfamily		 Helianthus annuus
TI:4232 None
 
T1EZZ4_HELRO
EnsemblMetazoa»
0.0
20202144 AMP-dependent synthetase/ligase
domain-containing protein		 Helobdella robusta
TI:6412 None
 
ACSF4_HUMAN
Ensembl»
1.0
AASDH Beta-alanine-activating enzyme (EC 6.2.1.-) (Acyl-CoA
synthetase family member 4) (Protein NRPS998)		 Homo sapiens
TI:9606 None
 
A0A8I7BD00_HORVV
EnsemblPlants»
0.0
4-coumarate--CoA ligase (EC 6.2.1.12) Hordeum vulgare
TI:4513 None
   
B7PZD5_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW010234 AMP dependent ligase, putative (EC
5.1.1.3) (AMP dependent ligase, putative (Fragment))		 Ixodes scapularis
TI:6945 None
 
B7Q793_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW011488 Peptide synthetase, putative (EC
5.1.1.11) (Peptide synthetase, putative (Fragment))		 Ixodes scapularis
TI:6945 None
 
A0A6P9EL02_JUGRE
EnsemblPlants»
0.0
LOC109018657 Acyl-activating enzyme 19 isoform X1 Juglans regia
TI:51240 None
 
A0A0U9HI43_KLENI
EnsemblPlants»
0.0
KFL_000060600 Carrier domain-containing protein Klebsormidium nitens
TI:105231 None
 
W5N9G5_LEPOC
Ensembl»
0.0
Aminoadipate-semialdehyde dehydrogenase Lepisosteus oculatus
TI:7918 None
 
A0A5F8A4V3_MACMU
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Macaca mulatta
TI:9544 None
   
A0A2C9VAE5_MANES
EnsemblPlants»
0.0
MANES_09G131500 Carrier domain-containing protein Manihot esculenta
TI:3983 None
 
G7LCR6_MEDTR
EnsemblPlants»
0.0
MTR_8g035620 AMP-dependent synthetase and
ligase family protein		 Medicago truncatula
TI:3880 None
 
F7DKF4_MONDO
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Monodelphis domestica
TI:13616 None
   
A9V587_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_10108 AMP-dependent synthetase/ligase
domain-containing protein		 Monosiga brevicollis
TI:81824 None
 
ACSF4_MOUSE
Ensembl»
3.1
Aasdh Beta-alanine-activating enzyme (EC 6.2.1.-) (Acyl-CoA synthetase
family member 4) (Protein LYS2 homolog)		 Mus musculus
TI:10090 None
 
A0A804HVM6_MUSAM
EnsemblPlants»
0.0
GSMUA_302110.1 4-coumarate--CoA ligase (EC 6.2.1.12) Musa acuminata
TI:4641 None
 
A0A1U8AKG4_NELNU
EnsemblBacteria»
0.0
LOC104605230 Acyl-activating enzyme 19 isoform X1 Nelumbo nucifera
TI:4432 None
 
A7RVL7_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g95034 AMP-dependent synthetase/ligase
domain-containing protein		 Nematostella vectensis
TI:45351 None
 
A7TCQ0_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g225329 Uncharacterized protein Nematostella vectensis
TI:45351 None 		 
 
A0A1S3X4E2_TOBAC
EnsemblFungi»
0.0
LOC107760944 Acyl-activating enzyme 19 isoform X1 Nicotiana tabacum
TI:4097 None
   
A0A1S4BEJ9_TOBAC
EnsemblFungi»
0.0
LOC107807467 Acyl-activating enzyme 19 isoform X1 Nicotiana tabacum
TI:4097 None
   
F6W7A3_ORNAN
Ensembl»
0.0
Carrier domain-containing protein Ornithorhynchus anatinus
TI:9258 None
   
A0A0P0WS15_ORYSJ
EnsemblPlants»
0.0
Os06g0111600 4-coumarate--CoA ligase (EC 6.2.1.12) Oryza sativa
TI:4530 None
 
H2L982_ORYLA
Ensembl»
0.0
aasdh Aminoadipate-semialdehyde dehydrogenase Oryzias latipes
TI:8090 None
   
K7C9C7_PANTR
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Pan troglodytes
TI:9598 None
 
A0A7I4ABU9_PHYPA
EnsemblPlants»
0.0
Carrier domain-containing protein Physcomitrium patens
TI:3218 None
 
A0A2K1WPH6_POPTR
EnsemblPlants»
0.0
POPTR_019G043800 Carrier domain-containing protein Populus trichocarpa
TI:3694 None
 
A0A2A6BQ49_PRIPA
EnsemblMetazoa»
0.0
WBGene00114305 AMP-binding protein Pristionchus pacificus
TI:54126 None 		 
 
A0A251QDM3_PRUPE
EnsemblPlants»
0.0
PRUPE_2G098200 Carrier domain-containing protein Prunus persica
TI:3760 None
 
D4A5F5_RAT
RGD»
1.5
Aasdh Aminoadipate-semialdehyde dehydrogenase Rattus norvegicus
TI:10116 None
   
Q7UKD4_RHOBA
EnsemblBacteria»
0.0
RB10706 Similar to serine/threonine protein
kinase related protein-putative PQQ-dependent oxidoreductase		 Rhodopirellula baltica
TI:265606 None
 
B9SDD9_RICCO
EnsemblBacteria»
0.0
RCOM_1516860 AMP dependent ligase, putative (EC 5.1.1.11) Ricinus communis
TI:3988 None
 
D8RRG7_SELML
EnsemblPlants»
0.0
SELMODRAFT_149203 Carrier domain-containing protein Selaginella moellendorffii
TI:88036 None
 
D8RXC6_SELML
EnsemblPlants»
0.0
SELMODRAFT_103915 Carrier domain-containing protein Selaginella moellendorffii
TI:88036 None
 
K3XUX5_SETIT
EnsemblPlants»
0.0
4-coumarate--CoA ligase (EC 6.2.1.12) Setaria italica
TI:4555 None
 
A0A3Q7F1X0_SOLLC
EnsemblPlants»
0.0
xyloglucan:xyloglucosyl transferase
(EC 2.4.1.207)		 Solanum lycopersicum
TI:4081 None
   
M0ZNM7_SOLTU
EnsemblPlants»
0.0
AMP dependent ligase Solanum tuberosum
TI:4113 None 		       
A0A1W0VR07_SORBI
EnsemblPlants»
0.0
SORBI_3010G009200 Carrier domain-containing protein Sorghum bicolor
TI:4558 None
 
A0A7M7NG43_STRPU
EnsemblMetazoa»
0.0
Carrier domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7NK29_STRPU
EnsemblMetazoa»
0.0
Carrier domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A287ABP0_PIG
Ensembl»
0.0
AASDH Aminoadipate-semialdehyde dehydrogenase Sus scrofa
TI:9823 None
   
A0A061F726_THECC
EnsemblPlants»
0.0
TCM_025682 AMP-dependent synthetase and ligase
family protein, putative isoform 1		 Theobroma cacao
TI:3641 None
 
D1ZZ87_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_08000 Luciferin 4-monooxygenase (EC 1.13.12.7) Tribolium castaneum
TI:7070 None
 
B3RXV2_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_56341 AMP-dependent synthetase/ligase
domain-containing protein		 Trichoplax adhaerens
TI:10228 None
 
A0A3B6H1R0_WHEAT
EnsemblPlants»
0.0
4-coumarate--CoA ligase (EC 6.2.1.12) Triticum aestivum
TI:4565 None
   
A0A3B6R792_WHEAT
EnsemblPlants»
0.0
CFC21_095292 4-coumarate--CoA ligase (EC 6.2.1.12) Triticum aestivum
TI:4565 None
 
A0A3B6RA89_WHEAT
EnsemblPlants»
0.0
CFC21_095048 4-coumarate--CoA ligase (EC 6.2.1.12) Triticum aestivum
TI:4565 None
 
A0A3B6SKX7_WHEAT
EnsemblPlants»
0.0
CFC21_105696 4-coumarate--CoA ligase (EC 6.2.1.12) Triticum aestivum
TI:4565 None
 
A0A3B6T7W6_WHEAT
EnsemblPlants»
0.0
CFC21_106646 4-coumarate--CoA ligase (EC 6.2.1.12) Triticum aestivum
TI:4565 None
 
F6I1S6_VITVI
EnsemblPlants»
0.0
VIT_15s0107g00450 AMP-dependent synthetase/ligase
domain-containing protein		 Vitis vinifera
TI:29760 None 		 
 
F6I1S7_VITVI
EnsemblPlants»
0.0
VIT_15s0107g00470 Acyl-activating enzyme 19 Vitis vinifera
TI:29760 None 		 
 
F6I1S8_VITVI
EnsemblPlants»
0.0
VIT_15s0107g00500 Acyl-activating enzyme 19 Vitis vinifera
TI:29760 None 		 
 
A0A6I8Q471_XENTR
Xenbase»
0.0
aasdh Aminoadipate-semialdehyde dehydrogenase (Beta-alanine-activating
enzyme isoform X1)		 Xenopus tropicalis
TI:8364 None
   
A0A1D6NWQ9_MAIZE
EnsemblPlants»
0.0
103638170 4-coumarate--CoA ligase (EC 6.2.1.12) Zea mays
TI:4577 None
 
A0A0K9NQ15_ZOSMR
EnsemblPlants»
0.0
ZOSMA_7G01840 Acyl-activating enzyme 19 Zostera marina
TI:29655 None 		 
 
A0A0K9PE29_ZOSMR
EnsemblPlants»
0.0
ZOSMA_29G01660 4-coumarate--CoA ligase (EC 6.2.1.12) Zostera marina
TI:29655 None