Cluster UKP04983
- TUBULIN--TYROSINE LIGASE-LIKE PROTEIN 12
Standard knownness: 4.0; Custom knownness: None; Num. species: 73; Orthology database: Panther19.0; Protein members: 85
Collated Gene Ontology terms
Biological process:
histone H4K20me2 reader activity(2025)
ligase activity(2025)
nucleotide binding(2025)
ATP binding(2025)
tubulin-tyrosine ligase activity(2019)
histone H4K20 trimethyltransferase activity(2023)
catalytic activity, acting on a protein(2025)
acid-amino acid ligase activity(2025)
tubulin-glutamic acid ligase activity(2021)
protein-glycine ligase activity(2018)
Molecular function:
regulation of mitotic cell cycle2019, 2025
negative regulation of type I interferon-mediated signaling pathway2019, 2025
chromatin organization2025
reproductive behavior2025
innate immune response2025
immune system process2025
protein polyglutamylation2021
mitotic cytokinesis2021
microtubule cytoskeleton organization2021
egg-laying behavior2016
cilium-dependent cell motility2021
Cellular component:
cytoplasm2019, 2023, 2025
cytosol2011, 2024, 2025
nucleoplasm2025
spindle2025
nucleus2025
midbody2025
centrosome2025
striated muscle dense body2012
sarcomere2012
plasma membrane2025
nuclear lumen2025
endoplasmic reticulum2012
Phylogenetic distribution
| Chordates: | 21/21 |  |
| Echinoderms: | 0/0 | |
| Hemichordates: | 0/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 3/3 | |
| Arthropods: | 5/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 0/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 1/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 1/3 | |
| Excavates: | 2/4 | |
| Harosa: | 2/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 36/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 |
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Proteins
| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
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TTL12_MOUSE Ensembl» |
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Ttll12 | Tubulin--tyrosine ligase-like protein 12 (Inactive tubulin--tyrosine ligase-like protein 12) |
Mus musculus TI:10090 None |
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TTL12_HUMAN Ensembl» |
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TTLL12 | Tubulin--tyrosine ligase-like protein 12 (Inactive tubulin--tyrosine ligase-like protein 12) |
Homo sapiens TI:9606 None |
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D4A1Q9_RAT RGD» |
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Ttll12 | Tubulin tyrosine ligase like 12 |
Rattus norvegicus TI:10116 None |
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H2QLU9_PANTR Ensembl» |
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TTLL12 | Tubulin tyrosine ligase like 12 (Tubulin tyrosine ligase-like family, member 12) |
Pan troglodytes TI:9598 None |
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Q08E58_BOVIN Ensembl» |
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TTLL12 | Tubulin tyrosine ligase like 12 (Tubulin tyrosine ligase-like family, member 12) |
Bos taurus TI:9913 None |
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A0A2I2Z835_GORGO Ensembl» |
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Tubulin tyrosine ligase like 12 |
Gorilla gorilla TI:9593 None |
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A0A5F7ZCP8_MACMU Ensembl» |
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TTLL12 | Tubulin tyrosine ligase like 12 |
Macaca mulatta TI:9544 None |
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A0A5F8H8I2_MONDO Ensembl» |
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TTLL12 | Tubulin tyrosine ligase like 12 |
Monodelphis domestica TI:13616 None |
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A0A5G2QLE8_PIG Ensembl» |
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TTLL12 | Tubulin tyrosine ligase like 12 |
Sus scrofa TI:9823 None |
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A0A6I8N2H2_ORNAN Ensembl» |
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TTLL12 | Tubulin tyrosine ligase like 12 |
Ornithorhynchus anatinus TI:9258 None |
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A0A8I3S0J8_CANLF Ensembl» |
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TTLL12 | Tubulin tyrosine ligase like 12 |
Canis lupus TI:9612 None |
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A0A8V0YBT4_CHICK Ensembl» |
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TTLL12 | Tubulin tyrosine ligase like 12 |
Gallus gallus TI:9031 None |
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F6WRP1_HORSE Ensembl» |
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TTLL12 | Tubulin tyrosine ligase like 12 |
Equus caballus TI:9796 None |
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TTL12_CAEEL WormBase» |
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ttll-12 | Tubulin--tyrosine ligase-like protein 12 (Inactive tubulin--tyrosine ligase-like protein 12) |
Caenorhabditis elegans TI:6239 None |
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Q386R8_TRYB2 TubercuList» |
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Tb11.02.0020 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Trypanosoma brucei TI:5691 None |
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TTL12_CAEBR WormBase» |
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ttll-12 | Tubulin--tyrosine ligase-like protein 12 (Inactive tubulin--tyrosine ligase-like protein 12) |
Caenorhabditis briggsae TI:6238 None |
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Q6IDC7_ARATH TAIR» |
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At1g77550 | At1g77550 (Tubulin-tyrosine ligase) |
Arabidopsis thaliana TI:3702 None |
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Q7JVG6_DROME FlyBase» |
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TTLL12 | LD38689p (Tubulin tyrosine ligase-like 12) |
Drosophila melanogaster TI:7227 None |
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A0A061GT18_THECC euHCVdb» |
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TCM_037527 | Tubulin-tyrosine ligases,tubulin-tyrosine ligases isoform 1 |
Theobroma cacao TI:3641 None |
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A0A072V887_MEDTR EnsemblPlants» |
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25486508 | Putative tubulin-tyrosine ligase/Tubulin polyglutamylase, leucine-rich repeat domain, L (Tubulin-tyrosine ligase family protein) |
Medicago truncatula TI:3880 None |
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A0A0K9PSA3_ZOSMR neXtProt» |
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ZOSMA_174G00300 | Tubulin-tyrosine ligase family protein, expressed |
Zostera marina TI:29655 None |
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A0A1D6PJ00_MAIZE EnsemblPlants» |
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ZEAMMB73_Zm00001d048282 | Tubulin-tyrosine ligase |
Zea mays TI:4577 None |
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A0A1L8GW47_XENLA Xenbase» |
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ttll12.L | Tubulin--tyrosine ligase-like protein 12 isoform X1 |
Xenopus laevis TI:8355 None |
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A0A1S3ZAF4_TOBAC euHCVdb» |
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LOC107784770 | Uncharacterized protein LOC107784770 |
Nicotiana tabacum TI:4097 None |
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A0A1S4CWA5_TOBAC euHCVdb» |
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LOC107823207 | Tubulin--tyrosine ligase-like protein 12 (Uncharacterized protein LOC107823207) |
Nicotiana tabacum TI:4097 None |
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A0A1Y1I280_KLENI neXtProt» |
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KFL_001260260 | Putative tubulin-tyrosine ligase |
Klebsormidium nitens TI:105231 None |
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A0A251UL78_HELAN euHCVdb» |
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HannXRQ_Chr06g0178331 HanXRQr2_Chr06g0259991 | Putative tubulin-tyrosine ligase (Tubulin-tyrosine ligase/Tubulin polyglutamylase, ATP-grasp, subdomain 1) |
Helianthus annuus TI:4232 None |
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A0A2A6D2Z7_PRIPA EnsemblMetazoa» |
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WBGene00112329 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Pristionchus pacificus TI:54126 None |
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A0A9R0ISJ0_SPIOL neXtProt» |
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LOC110792959 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Spinacia oleracea TI:3562 None |
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A2DIM0_TRIV3 TubercuList» |
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TVAG_178680 | Tubulin-tyrosine ligase family protein |
Trichomonas vaginalis TI:5722 None |
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A2DKV2_TRIV3 TubercuList» |
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TVAG_146480 | Tubulin-tyrosine ligase family protein |
Trichomonas vaginalis TI:5722 None |
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Q10QY3_ORYSJ neXtProt» |
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LOC_Os03g08140 Os03g0179000 | Os03g0179000 protein (Tubulin-tyrosine ligase family protein, expressed) |
Oryza sativa TI:4530 None |
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Q386S0_TRYB2 TubercuList» |
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Tb11.22.0002 | Uncharacterized protein |
Trypanosoma brucei TI:5691 None |
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A0A022QD33_ERYGU euHCVdb» |
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MIMGU_mgv1a001206mg | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Erythranthe guttata TI:4155 None |
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A0A0A0LWN5_CUCSA euHCVdb» |
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Csa_1G596500 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Cucumis sativus TI:3659 None |
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A0A0R0IDU6_SOYBN EnsemblPlants» |
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GLYMA_09G069600 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Glycine max TI:3847 None |
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A0A1U8A5X1_NELNU euHCVdb» |
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LOC104600552 | Tubulin--tyrosine ligase-like protein 12 |
Nelumbo nucifera TI:4432 None |
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A0A2C9W6V8_MANES euHCVdb» |
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MANES_03G040400v8 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Manihot esculenta TI:3983 None |
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A0A2G2ZA81_CAPAN euHCVdb» |
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T459_16969 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Capsicum annuum TI:4072 None |
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A0A2I4GJX3_JUGRE euHCVdb» |
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LOC109008528 | Tubulin--tyrosine ligase-like protein 12 |
Juglans regia TI:51240 None |
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A0A2K1KGF1_PHYPA EnsemblPlants» |
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PHYPA_009220 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Physcomitrium patens TI:3218 None |
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A0A2R6WBW4_MARPO neXtProt» |
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MARPO_0113s0055 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Marchantia polymorpha TI:3197 None |
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A0A3B3I5Q4_ORYLA Ensembl» |
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TTLL12 | Tubulin tyrosine ligase-like family, member 12 |
Oryzias latipes TI:8090 None |
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A0A3B6HM43_WHEAT EnsemblPlants» |
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LOC123084720 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Triticum aestivum TI:4565 None |
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A0A3B6JLT7_WHEAT EnsemblPlants» |
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LOC123098648 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Triticum aestivum TI:4565 None |
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A0A3Q7H935_SOLLC EnsemblPlants» |
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LOC101252792 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Solanum lycopersicum TI:4081 None |
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A0A6I8PUC4_XENTR Xenbase» |
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ttll12 | Tubulin tyrosine ligase-like 12 (Tubulin--tyrosine ligase-like protein 12 isoform X1) |
Xenopus tropicalis TI:8364 None |
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A0A804KXC9_MUSAM EnsemblPlants» |
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GSMUA_320530.1 | (wild Malaysian banana) hypothetical protein |
Musa acuminata TI:4641 None |
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A0A8I6X4T1_HORVV EnsemblPlants» |
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LOC123449605 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Hordeum vulgare TI:4513 None |
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A0A9J7HR60_BRAFL neXtProt» |
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LOC118406727 | Tubulin--tyrosine ligase-like protein 12 isoform X1 |
Branchiostoma floridae TI:7739 None |
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A0ABM3AA66_GOSHI neXtProt» |
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LOC107901062 | Tubulin--tyrosine ligase-like protein 12 |
Gossypium hirsutum TI:3635 None |
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A0ABM3BVZ7_GOSHI neXtProt» |
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LOC107952189 | Tubulin--tyrosine ligase-like protein 12 |
Gossypium hirsutum TI:3635 None |
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A0DWM6_PARTE euHCVdb» |
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GSPATT00021086001 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Paramecium tetraurelia TI:5888 None |
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A7RF17_NEMVE neXtProt» |
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NEMVEDRAFT_v1g78861 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Nematostella vectensis TI:45351 None |
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A7SHP9_NEMVE euHCVdb» |
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NEMVEDRAFT_v1g245344 | CS domain-containing protein |
Nematostella vectensis TI:45351 None |
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B9MSZ1_POPTR euHCVdb» |
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POPTR_006G141900 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Populus trichocarpa TI:3694 None |
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B9RRA6_RICCO neXtProt» |
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RCOM_0711900 | Protein binding protein, putative |
Ricinus communis TI:3988 None |
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C4M2T0_ENTH1 TubercuList» |
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EHI_076890 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Entamoeba histolytica TI:5759 None |
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C5WVS3_SORBI euHCVdb» |
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SORBI_3001G483800 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Sorghum bicolor TI:4558 None |
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D6WTU6_TRICA CTD» |
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AUGUSTUS-3.0.2_15929 | Tubulin--tyrosine ligase-like protein 12 |
Tribolium castaneum TI:7070 None |
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D7TCF1_VITVI euHCVdb» |
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VIT_11s0016g01120 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Vitis vinifera TI:29760 None |
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D8RZ55_SELML euHCVdb» |
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SELMODRAFT_105046 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Selaginella moellendorffii TI:88036 None |
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D8SRL6_SELML euHCVdb» |
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SELMODRAFT_123017 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Selaginella moellendorffii TI:88036 None |
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E9FRH2_DAPPU euHCVdb» |
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DAPPUDRAFT_310030 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Daphnia pulex TI:6669 None |
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F4NXA3_BATDJ euHCVdb» |
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BATDEDRAFT_86118 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Batrachochytrium dendrobatidis TI:109871 None |
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F6SYW5_CIOIN Ensembl» |
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Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Ciona intestinalis TI:7719 None |
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H3GQC7_PHYRM EnsemblProtists» |
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Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Phytophthora ramorum TI:164328 None |
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I1H926_BRADI EnsemblPlants» |
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LOC100837823 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Brachypodium distachyon TI:15368 None |
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I1MHF8_SOYBN EnsemblPlants» |
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LOC100809212 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Glycine max TI:3847 None |
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K4A5J2_SETIT EnsemblPlants» |
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LOC101784720 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Setaria italica TI:4555 None |
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M1BN37_SOLTU EnsemblPlants» |
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LOC102605923 | Tubulin--tyrosine ligase 12 |
Solanum tuberosum TI:4113 None |
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M4EH54_BRACM EnsemblPlants» |
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Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Brassica campestris TI:3711 None |
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M5VWP3_PRUPE euHCVdb» |
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PRUPE_7G198800 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Prunus persica TI:3760 None |
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Q7PQC2_ANOGA EnsemblMetazoa» |
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1274434 | AGAP004284-PA |
Anopheles gambiae TI:7165 None |
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Q7ZUQ4_DANRE ZFIN» |
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ttll12 | Tubulin--tyrosine ligase-like protein 12 (Zgc:55343) |
Danio rerio TI:7955 None |
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T1FMW9_HELRO EnsemblMetazoa» |
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20210168 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Helobdella robusta TI:6412 None |
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W1PTX5_AMBTC euHCVdb» |
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AMTR_s00024p00238810 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Amborella trichopoda TI:13333 None |
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W5ND60_LEPOC Ensembl» |
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Tubulin tyrosine ligase-like family, member 12 |
Lepisosteus oculatus TI:7918 None |
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A0A067G2U4_CITSI neXtProt» |
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CISIN_1g0028801mg | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Citrus sinensis TI:2711 None |
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A0A067GEN9_CITSI euHCVdb» |
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CISIN_1g0028802mg | Tubulin-tyrosine ligase |
Citrus sinensis TI:2711 None |
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A0A2G2Z283_CAPAN neXtProt» |
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T459_19652 | Uncharacterized protein |
Capsicum annuum TI:4072 None |
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A0A2G2Z2K1_CAPAN euHCVdb» |
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T459_19653 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Capsicum annuum TI:4072 None |
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A0A2I2ZTS7_GORGO Ensembl» |
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Tubulin tyrosine ligase like 12 |
Gorilla gorilla TI:9593 None |
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A0ABI7ZRJ5_FELCA Ensembl» |
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TTLL12 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Felis catus TI:9685 None |
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B7PVW0_IXOSC EnsemblMetazoa» |
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IscW_ISCW008116 | Tubulin--tyrosine ligase-like protein 12 SET-like domain-containing protein |
Ixodes scapularis TI:6945 None |
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