Collated Gene Ontology terms

Biological process: chromatin binding(2010)

Molecular function: DNA replication2010, 2020, 2024, 2025 DNA-templated DNA replication2013, 2025 double-strand break repair via break-induced replication2013, 2017, 2025 chromosome segregation2016, 2025 DNA replication initiation2005, 2008, 2016, 2020 inner cell mass cell proliferation2014 mitotic cell cycle2010 cell cycle DNA replication2016

Cellular component: GINS complex2007, 2008, 2010, 2013, 2016, 2020, 2025 nucleus2006, 2009, 2010, 2011, 2016, 2018, 2024, 2025 chromosome2025 cytoplasm2006, 2018, 2025 CMG complex2017, 2020, 2025 nucleoplasm2013, 2018, 2025 DNA replication preinitiation complex2013, 2025 nuclear replication fork2024, 2025 cytosol2009

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 3/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
Q9VBI1_DROME
FlyBase»
3.7
Sld5 DNA replication complex GINS protein SLD5 Drosophila melanogaster
TI:7227 None
 
SLD5_YEAST
SGD»
3.5
SLD5 DNA replication complex GINS protein SLD5 Saccharomyces cerevisiae
TI:4932 None
 
SLD5_MOUSE
Ensembl»
2.4
Gins4 DNA replication complex GINS protein SLD5 (GINS complex subunit 4)
[Cleaved into: DNA replication complex GINS protein SLD5, N-terminally processed]		 Mus musculus
TI:10090 None
 
SLD5_HUMAN
Ensembl»
1.9
GINS4 DNA replication complex GINS protein SLD5 (GINS complex subunit 4)
[Cleaved into: DNA replication complex GINS protein SLD5, N-terminally processed]		 Homo sapiens
TI:9606 None
 
SLD5_RAT
RGD»
1.5
Gins4 DNA replication complex GINS protein SLD5 (GINS complex subunit 4)
[Cleaved into: DNA replication complex GINS protein SLD5, N-terminally processed]		 Rattus norvegicus
TI:10116 None
 
SLD5_SCHPO
PomBase»
1.5
sld5 DNA replication complex GINS protein sld5 Schizosaccharomyces pombe
TI:4896 None
 
SLD5_ARATH
TAIR»
1.4
SLD5 DNA replication complex GINS protein SLD5 (Protein EMBRYO
DEFECTIVE 2812) (Protein SYNTHETIC LETHALITY WITH DPB11-1 5)		 Arabidopsis thaliana
TI:3702 None
 
SLD5_DICDI
dictyBase»
1.0
gins4 DNA replication complex GINS protein
SLD5 (GINS complex subunit 4)		 Dictyostelium discoideum
TI:44689 None
 
A0A2R8Q9M1_DANRE
ZFIN»
0.5
gins4 DNA replication complex GINS protein SLD5 Danio rerio
TI:7955 None
 
Q9U2W9_CAEEL
WormBase»
0.5
sld-5 DNA replication complex GINS protein SLD5 Caenorhabditis elegans
TI:6239 None
 
A0A022QLU3_ERYGU
euHCVdb»
0.0
MIMGU_mgv1a013438mg DNA replication complex GINS protein SLD5 Erythranthe guttata
TI:4155 None
 
A0A061EPJ2_THECC
euHCVdb»
0.0
TCM_021388 DNA replication complex GINS protein SLD5 Theobroma cacao
TI:3641 None
 
A0A067G8X4_CITSI
euHCVdb»
0.0
CISIN_1g027653mg DNA replication complex GINS protein SLD5 Citrus sinensis
TI:2711 None
 
A0A0A0L8W0_CUCSA
euHCVdb»
0.0
Csa_3G121760 DNA replication complex GINS protein SLD5 Cucumis sativus
TI:3659 None
 
A0A0K9PRN0_ZOSMR
euHCVdb»
0.0
ZOSMA_179G00250 DNA replication complex GINS protein SLD5 Zostera marina
TI:29655 None
 
A0A0P0WHT3_ORYSJ
euHCVdb»
0.0
Os05g0143400 DNA replication complex GINS protein SLD5 Oryza sativa
TI:4530 None
 
A0A0S2M600_CRYD1
TubercuList»
0.0
CNG02235 DNA replication complex GINS protein SLD5 Cryptococcus deneoformans
TI:40410 None
 
A0A1D8PU96_CANAL
CGD»
0.0
SLD5 DNA replication complex GINS protein SLD5 Candida albicans
TI:5476 None
 
A0A1S4B8M2_TOBAC
euHCVdb»
0.0
LOC107805638 DNA replication complex GINS protein SLD5 Nicotiana tabacum
TI:4097 None
   
A0A1S4DBV5_TOBAC
euHCVdb»
0.0
LOC107828148 DNA replication complex GINS protein SLD5 Nicotiana tabacum
TI:4097 None
   
A0A1U8ABZ2_NELNU
euHCVdb»
0.0
LOC104598745 DNA replication complex GINS protein SLD5 Nelumbo nucifera
TI:4432 None
   
A0A1U8ILN9_GOSHI
euHCVdb»
0.0
LOC107896602 DNA replication complex GINS protein SLD5 Gossypium hirsutum
TI:3635 None
   
A0A1U8KEN8_GOSHI
euHCVdb»
0.0
LOC107916232 DNA replication complex GINS protein SLD5 Gossypium hirsutum
TI:3635 None
   
A0A1Y1IAE0_KLENI
euHCVdb»
0.0
KFL_002480040 DNA replication complex GINS protein SLD5 Klebsormidium nitens
TI:105231 None
 
A0A251QWZ9_PRUPE
euHCVdb»
0.0
PRUPE_1G115500 DNA replication complex GINS protein SLD5 Prunus persica
TI:3760 None
 
A0A251RQN4_HELAN
euHCVdb»
0.0
SLD5 DNA replication complex GINS protein SLD5 Helianthus annuus
TI:4232 None
 
A0A251TJ53_HELAN
euHCVdb»
0.0
SLD5 DNA replication complex GINS protein SLD5 Helianthus annuus
TI:4232 None
 
A0A287BEE8_PIG
Ensembl»
0.0
GINS4 DNA replication complex GINS protein SLD5 Sus scrofa
TI:9823 None
   
A0A2A6C609_PRIPA
EnsemblMetazoa»
0.0
WBGene00093448 Spd-1 Pristionchus pacificus
TI:54126 None
   
A0A2C9WAY8_MANES
euHCVdb»
0.0
MANES_03G206000v8 DNA replication complex GINS protein SLD5 Manihot esculenta
TI:3983 None
 
A0A2G2YG66_CAPAN
euHCVdb»
0.0
T459_28204 Uncharacterized protein Capsicum annuum
TI:4072 None
 
A0A2G2ZJG9_CAPAN
euHCVdb»
0.0
T459_15148 DNA replication complex GINS protein SLD5 Capsicum annuum
TI:4072 None
 
A0A2I2ZYR7_GORGO
Ensembl»
0.0
GINS4 DNA replication complex GINS protein SLD5 Gorilla gorilla
TI:9593 None
 
A0A2I3SZ33_PANTR
Ensembl»
0.0
GINS4 DNA replication complex GINS protein SLD5 Pan troglodytes
TI:9598 None
 
A0A2I4F1Q8_JUGRE
euHCVdb»
0.0
LOC108994712 DNA replication complex GINS protein SLD5 Juglans regia
TI:51240 None
   
A0A2K1YU49_POPTR
euHCVdb»
0.0
POPTR_010G147000 Uncharacterized protein Populus trichocarpa
TI:3694 None
 
A0A2K1ZF13_POPTR
euHCVdb»
0.0
POPTR_008G103800 DNA replication complex GINS protein SLD5 Populus trichocarpa
TI:3694 None
 
A0A2K3DDC1_CHLRE
euHCVdb»
0.0
CHLRE_09g393600v5 DNA replication complex GINS protein SLD5 Chlamydomonas reinhardtii
TI:3055 None
 
A0A2R6X982_MARPO
euHCVdb»
0.0
MARPO_0029s0136 DNA replication complex GINS protein SLD5 Marchantia polymorpha
TI:3197 None
 
A0A3B6ENX8_WHEAT
EnsemblPlants»
0.0
LOC123062933 DNA replication complex GINS protein SLD5 Triticum aestivum
TI:4565 None
   
A0A3B6H0A9_WHEAT
EnsemblPlants»
0.0
LOC123080121 DNA replication complex GINS protein SLD5 Triticum aestivum
TI:4565 None
   
A0A3P5Z7L5_BRACM
EnsemblPlants»
0.0
BRAA06T26778Z BRAPAZ1V2_A06P46220.2 DNA replication complex GINS protein SLD5 Brassica campestris
TI:3711 None
 
A0A3Q7JNQ8_SOLLC
EnsemblPlants»
0.0
LOC101252143 DNA replication complex GINS protein SLD5 Solanum lycopersicum
TI:4081 None
   
A0A7M7NUQ6_STRPU
EnsemblMetazoa»
0.0
DNA replication complex GINS protein SLD5 Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7PCY0_STRPU
EnsemblMetazoa»
0.0
DNA replication complex GINS protein SLD5 Strongylocentrotus purpuratus
TI:7668 None
   
A0A7U2HYM4_PHANO
TubercuList»
0.0
JI435_028780 DNA replication complex GINS protein SLD5 Phaeosphaeria nodorum
TI:13684 None
 
A0A803KI80_XENTR
Xenbase»
0.0
gins4 DNA replication complex GINS protein SLD5 Xenopus tropicalis
TI:8364 None
 
A0A804J7X5_MUSAM
EnsemblPlants»
0.0
GSMUA_275980.1 DNA replication complex GINS protein SLD5 Musa acuminata
TI:4641 None
 
A0A804N8S0_MAIZE
EnsemblPlants»
0.0
Uncharacterized protein Zea mays
TI:4577 None
   
A0A804RCS9_MAIZE
EnsemblPlants»
0.0
Uncharacterized protein Zea mays
TI:4577 None
   
A0A804RHI1_MAIZE
EnsemblPlants»
0.0
DNA replication complex GINS
protein SLD5 C-terminal domain-containing protein		 Zea mays
TI:4577 None
   
A0A8I3MZZ1_CANLF
Ensembl»
0.0
GINS4 DNA replication complex GINS protein
SLD5 (GINS complex subunit 4)		 Canis lupus
TI:9612 None
   
A0A8J1MGY0_XENLA
Xenbase»
0.0
gins4.L DNA replication complex GINS protein SLD5 Xenopus laevis
TI:8355 None
   
A0A9J7HKQ3_BRAFL
euHCVdb»
0.0
LOC118404736 DNA replication complex GINS protein SLD5 Branchiostoma floridae
TI:7739 None
   
A0A9K3DK68_HELAN
euHCVdb»
0.0
HanXRQr2_Chr17g0811111 DNA replication complex GINS protein SLD5 Helianthus annuus
TI:4232 None
 
A0A9K3HXC6_HELAN
euHCVdb»
0.0
HanXRQr2_Chr10g0435121 DNA replication complex GINS protein SLD5 Helianthus annuus
TI:4232 None
 
A0A9L0SZJ2_HORSE
Ensembl»
0.0
GINS4 DNA replication complex GINS protein SLD5 Equus caballus
TI:9796 None
   
A0A9R0J9L0_SPIOL
euHCVdb»
0.0
LOC110801463 DNA replication complex GINS protein SLD5 Spinacia oleracea
TI:3562 None
   
A0A9R1FP38_WHEAT
EnsemblPlants»
0.0
LOC123071800 DNA replication complex GINS protein SLD5 Triticum aestivum
TI:4565 None
 
A0A9R1UUJ1_LACSA
neXtProt»
0.0
LSAT_V11C800445220 GINS subunit domain-containing protein Lactuca sativa
TI:4236 None
 
A0ABI7YZV6_FELCA
Ensembl»
0.0
GINS4 DNA replication complex GINS protein SLD5 Felis catus
TI:9685 None
   
A0CMA2_PARTE
euHCVdb»
0.0
GSPATT00008398001 GINS subunit domain-containing protein Paramecium tetraurelia
TI:5888 None
 
A0D3B1_PARTE
euHCVdb»
0.0
GSPATT00013013001 DNA replication complex GINS protein SLD5 Paramecium tetraurelia
TI:5888 None
 
A7EX35_SCLS1
TubercuList»
0.0
SS1G_09894 DNA replication complex GINS protein SLD5 Sclerotinia sclerotiorum
TI:5180 None
 
A7SEX8_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g237188 DNA replication complex GINS protein SLD5 Nematostella vectensis
TI:45351 None
 
A7TBF5_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g153503 DNA replication complex GINS protein
SLD5 (GINS complex subunit 4)		 Nematostella vectensis
TI:45351 None
 
A8BHG7_GIAIC
TubercuList»
0.0
GL50803_009477 GINS subunit domain-containing protein Giardia intestinalis
TI:5741 None
 
A8XGN5_CAEBR
WormBase»
0.0
sld-5 DNA replication complex GINS protein SLD5 Caenorhabditis briggsae
TI:6238 None
 
A9SRN0_PHYPA
EnsemblPlants»
0.0
LOC112289285 DNA replication complex GINS protein SLD5 Physcomitrium patens
TI:3218 None
 
A9URY3_MONBE
euHCVdb»
0.0
MONBRDRAFT_22745 DNA replication complex GINS protein SLD5 Monosiga brevicollis
TI:81824 None
 
B3RSV2_TRIAD
CTD»
0.0
TRIADDRAFT_23024 DNA replication complex GINS protein SLD5 Trichoplax adhaerens
TI:10228 None
 
B6JYG2_SCHJY
TubercuList»
0.0
sld5 DNA replication complex GINS protein SLD5 Schizosaccharomyces japonicus
TI:4897 None
 
B7QDF6_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW022133 DNA replication complex
GINS protein SLD5, putative		 Ixodes scapularis
TI:6945 None
 
B8BYC5_THAPS
euHCVdb»
0.0
THAPSDRAFT_21846 DNA replication complex GINS protein SLD5 Thalassiosira pseudonana
TI:35128 None
 
B9RZS6_RICCO
euHCVdb»
0.0
RCOM_1000840 DNA replication complex GINS protein SLD5 Ricinus communis
TI:3988 None
 
C0PJF4_MAIZE
EnsemblPlants»
0.0
LOC100193079 DNA replication complex GINS protein SLD5 Zea mays
TI:4577 None
 
C4MBA5_ENTH1
TubercuList»
0.0
EHI_048430 DNA replication complex GINS protein SLD5 Entamoeba histolytica
TI:5759 None
 
C5YZN7_SORBI
euHCVdb»
0.0
SORBI_3009G038800 DNA replication complex GINS protein SLD5 Sorghum bicolor
TI:4558 None
 
D6WLS6_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_13396 DNA replication complex GINS protein SLD5 Tribolium castaneum
TI:7070 None
 
D7SYJ7_VITVI
euHCVdb»
0.0
VIT_05s0077g00800 DNA replication complex GINS protein SLD5 Vitis vinifera
TI:29760 None
 
D8R4R6_SELML
euHCVdb»
0.0
SELMODRAFT_84583 DNA replication complex GINS protein SLD5 Selaginella moellendorffii
TI:88036 None
 
D8RJY6_SELML
euHCVdb»
0.0
SELMODRAFT_270905 DNA replication complex GINS protein SLD5 Selaginella moellendorffii
TI:88036 None
 
E3KWU9_PUCGT
TubercuList»
0.0
PGTG_14732 DNA replication complex GINS protein SLD5 Puccinia graminis
TI:5297 None
 
E9AE88_LEIMA
TubercuList»
0.0
LMJF_29_2260 DNA replication complex GINS protein SLD5 Leishmania major
TI:5664 None
 
E9GL26_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_304303 DNA replication complex GINS protein SLD5 Daphnia pulex
TI:6669 None
 
F0ZLL1_DICPU
TubercuList»
0.0
DICPUDRAFT_79109 DNA replication complex GINS protein SLD5 Dictyostelium purpureum
TI:5786 None
 
F2EH43_HORVV
EnsemblPlants»
0.0
LOC123445112 DNA replication complex GINS protein SLD5 Hordeum vulgare
TI:4513 None
 
F4P839_BATDJ
euHCVdb»
0.0
BATDEDRAFT_26664 DNA replication complex GINS protein SLD5 Batrachochytrium dendrobatidis
TI:109871 None
 
F6H6X2_VITVI
euHCVdb»
0.0
VIT_05s0077g00120 DNA replication complex GINS protein SLD5 Vitis vinifera
TI:29760 None
 
F6XB21_ORNAN
Ensembl»
0.0
GINS4 DNA replication complex GINS protein SLD5 Ornithorhynchus anatinus
TI:9258 None
   
F7BEK1_CIOIN
Ensembl»
0.0
DNA replication complex GINS protein SLD5 Ciona intestinalis
TI:7719 None
 
F7E9E1_MACMU
Ensembl»
0.0
GINS4 DNA replication complex GINS protein SLD5 Macaca mulatta
TI:9544 None
 
F7F7I1_MONDO
Ensembl»
0.0
GINS4 DNA replication complex GINS protein SLD5 Monodelphis domestica
TI:13616 None
   
H2M7U6_ORYLA
Ensembl»
0.0
GINS4 DNA replication complex GINS protein SLD5 Oryzias latipes
TI:8090 None
   
H3GIC8_PHYRM
EnsemblProtists»
0.0
DNA replication complex GINS protein SLD5 Phytophthora ramorum
TI:164328 None
 
H9G413_ANOCA
Ensembl»
0.0
GINS4 DNA replication complex GINS protein SLD5 Anolis carolinensis
TI:28377 None
   
I1HU22_BRADI
EnsemblPlants»
0.0
LOC100825702 DNA replication complex GINS protein SLD5 Brachypodium distachyon
TI:15368 None
 
I1KUV6_SOYBN
EnsemblPlants»
0.0
LOC100784291 DNA replication complex GINS protein SLD5 Glycine max
TI:3847 None
 
I3SQA1_MEDTR
EnsemblPlants»
0.0
25486583 DNA replication complex GINS protein SLD5 Medicago truncatula
TI:3880 None
 
K3XZ49_SETIT
EnsemblPlants»
0.0
LOC101779197 DNA replication complex GINS protein SLD5 Setaria italica
TI:4555 None
 
K3Z9H5_SETIT
EnsemblPlants»
0.0
LOC101781974 DNA replication complex GINS protein SLD5 Setaria italica
TI:4555 None
 
K7KYZ1_SOYBN
EnsemblPlants»
0.0
LOC100814216 DNA replication complex GINS protein SLD5 Glycine max
TI:3847 None
 
M1ABE8_SOLTU
EnsemblPlants»
0.0
LOC102596612 DNA replication complex GINS protein SLD5 Solanum tuberosum
TI:4113 None
   
Q4WMZ2_ASPFU
TubercuList»
0.0
AFUA_6G08210 DNA replication complex GINS protein SLD5 Aspergillus fumigatus
TI:746128 None
 
Q582Q4_TRYB2
TubercuList»
0.0
Tb03.48K5.420 DNA replication complex GINS protein SLD5 Trypanosoma brucei
TI:5691 None
 
Q5B690_EMENI
TubercuList»
0.0
ANIA_03940 DNA replication complex GINS protein SLD5 Emericella nidulans
TI:162425 None
 
Q7PX18_ANOGA
EnsemblMetazoa»
0.0
1282001 DNA replication complex GINS protein SLD5 Anopheles gambiae
TI:7165 None
 
Q7SF49_NEUCR
TubercuList»
0.0
NCU09261 DNA replication complex GINS protein SLD5 Neurospora crassa
TI:5141 None
 
SLD5_BOVIN
Ensembl»
0.0
GINS4 DNA replication complex GINS protein
SLD5 (GINS complex subunit 4)		 Bos taurus
TI:9913 None
 
SLD5_EREGS
EnsemblFungi»
0.0
SLD5 DNA replication complex GINS protein SLD5 Eremothecium gossypii
TI:33169 None
 
SLD5_XENLA
Xenbase»
0.0
gins4 DNA replication complex GINS protein
SLD5 (GINS complex subunit 4)		 Xenopus laevis
TI:8355 None
 
SLD5_YARLI
EnsemblFungi»
0.0
SLD5 DNA replication complex GINS protein SLD5 Yarrowia lipolytica
TI:4952 None
 
T1G1H7_HELRO
EnsemblMetazoa»
0.0
20214925 GINS complex subunit 4 Helobdella robusta
TI:6412 None
 
W1PDW2_AMBTC
neXtProt»
0.0
AMTR_s00006p00258700 GINS subunit domain-containing protein Amborella trichopoda
TI:13333 None
 
W5NGR2_LEPOC
Ensembl»
0.0
DNA replication complex GINS protein SLD5 Lepisosteus oculatus
TI:7918 None