Collated Gene Ontology terms

Biological process: guanylate cyclase activity(2019, 2024) lyase activity(2024)

Molecular function: cGMP biosynthetic process2019, 2024 response to cAMP2022, 2024 liver regeneration2022, 2024

Cellular component:

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 36/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»
Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
W1PVZ4_AMBTC
EnsemblPlants»
0.0
AMTR_s00165p00042340 Guanylyl cyclase Amborella trichopoda
TI:13333 None
 
A0A1S4H619_ANOGA
EnsemblMetazoa»
0.0
Uncharacterized protein Anopheles gambiae
TI:7165 None
   
GCC1_ARATH
TAIR»
1.6
GC1 Guanylyl cyclase 1 (AtGC1) (EC 4.6.1.2) Arabidopsis thaliana
TI:3702 None
 
F4P887_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_12878 Guanylyl cyclase Batrachochytrium dendrobatidis
TI:109871 None
   
A0A3Q1LUU6_BOVIN
Ensembl»
0.0
GUCD1 Guanylyl cyclase domain containing 1 Bos taurus
TI:9913 None
     
I1HIV1_BRADI
EnsemblPlants»
0.0
100824072 Guanylyl cyclase Brachypodium distachyon
TI:15368 None
 
A0A9J7LKV4_BRAFL
CTD»
0.0
LOC118421547 Protein GUCD1-like Branchiostoma floridae
TI:7739 None
     
M4CY54_BRACM
EnsemblPlants»
0.0
Protein GUCD1 Brassica campestris
TI:3711 None
     
A0A8I3P4Q5_CANLF
Ensembl»
0.0
Uncharacterized protein Canis lupus
TI:9612 None
     
A0A8I3PRX5_CANLF
Ensembl»
0.0
GUCD1 Uncharacterized protein Canis lupus
TI:9612 None
     
A0A1U8GAG9_CAPAN
EnsemblPlants»
0.0
T459_08999 Protein GUCD1 Capsicum annuum
TI:4072 None
   
A0A2K3DBN7_CHLRE
EnsemblPlants»
0.0
CHLRE_10g457450v5 Guanylyl cyclase Chlamydomonas reinhardtii
TI:3055 None
   
F6YTC9_CIOIN
Ensembl»
0.0
Uncharacterized protein Ciona intestinalis
TI:7719 None
   
A0A067FPD1_CITSI
Ensembl»
0.0
CISIN_1g0243821mg Peptidase C39-like domain-containing protein Citrus sinensis
TI:2711 None
   
A0A067G0M6_CITSI
Ensembl»
0.0
CISIN_1g0243822mg Guanylyl cyclase Citrus sinensis
TI:2711 None
   
A0A0A0K8F6_CUCSA
EnsemblPlants»
0.0
Csa_6G009370 Guanylyl cyclase Cucumis sativus
TI:3659 None
 
Q08CN7_DANRE
ZFIN»
0.0
zgc:152874 Guanylyl cyclase domain-containing
1 (Protein GUCD1) (Zgc:152874)
Danio rerio
TI:7955 None
   
F0Z707_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_146833 Guanylyl cyclase Dictyostelium purpureum
TI:5786 None
   
Q54TH3_DICDI
dictyBase»
0.0
DDB_G0281749 Guanylyl cyclase Dictyostelium discoideum
TI:44689 None
   
Q9W4Y0_DROME
FlyBase»
0.0
EG:BACR25B3.6 RE44620p (Uncharacterized protein, isoform C) Drosophila melanogaster
TI:7227 None
   
A0A3Q2LB50_HORSE
Ensembl»
0.0
GUCD1 Guanylyl cyclase domain containing 1 Equus caballus
TI:9796 None
     
A0A022R8Q3_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a011515mg Guanylyl cyclase Erythranthe guttata
TI:4155 None
   
A0A058ZT12_EUCGR
EnsemblPlants»
0.0
EUGRSUZ_L02372 Guanylyl cyclase Eucalyptus grandis
TI:71139 None
   
A0A337S624_FELCA
Ensembl»
0.0
LOC101100863 Guanylyl cyclase domain containing 1 Felis catus
TI:9685 None
   
A0A337SRL1_FELCA
Ensembl»
0.0
GUCD1 Guanylyl cyclase domain containing 1 Felis catus
TI:9685 None
   
A0A8V1A8C8_CHICK
Ensembl»
0.0
GUCD1 Guanylyl cyclase domain containing 1 Gallus gallus
TI:9031 None
     
I1LML3_SOYBN
EnsemblPlants»
0.0
GLYMA_11G225300 Guanylyl cyclase Glycine max
TI:3847 None
   
K7MPM8_SOYBN
EnsemblPlants»
0.0
100037468 Guanylyl cyclase Glycine max
TI:3847 None
   
A0A2I2ZTB9_GORGO
Ensembl»
0.0
Guanylyl cyclase domain containing 1 Gorilla gorilla
TI:9593 None
   
A0A1U8KGG2_GOSHI
Ensembl»
0.0
LOC107916717 Protein GUCD1-like isoform X1 Gossypium hirsutum
TI:3635 None
     
A0A1U8LPX3_GOSHI
Ensembl»
0.0
LOC107929619 Protein GUCD1-like isoform X1 Gossypium hirsutum
TI:3635 None
     
A0A1U8N6V6_GOSHI
Ensembl»
0.0
LOC107944280 Protein GUCD1-like Gossypium hirsutum
TI:3635 None
     
A0A1U8NTJ7_GOSHI
Ensembl»
0.0
LOC107951688 Protein GUCD1-like isoform X1 Gossypium hirsutum
TI:3635 None
     
A0A251TSW0_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr09g0246921 HanXRQr2_Chr09g0381861 Guanylate cyclase (EC
4.6.1.2) (Putative guanylyl cyclase)
Helianthus annuus
TI:4232 None
 
A0A251UG19_HELAN
EnsemblPlants»
0.0
ATGC1 Guanylate cyclase (EC 4.6.1.2)
(Putative guanylyl cyclase 1)
Helianthus annuus
TI:4232 None
 
T1FNC8_HELRO
EnsemblMetazoa»
0.0
20210325 Protein GUCD1 Helobdella robusta
TI:6412 None
   
GUCD1_HUMAN
Ensembl»
0.0
GUCD1 Protein GUCD1 (Guanylyl cyclase
domain-containing protein 1) (Protein LLN4)
Homo sapiens
TI:9606 None
 
A0A8I6WHZ1_HORVV
EnsemblPlants»
0.0
Guanylyl cyclase Hordeum vulgare
TI:4513 None
     
B7QLQ0_IXOSC
EnsemblMetazoa»
0.0
8043144 Protein GUCD1 Ixodes scapularis
TI:6945 None
   
A0A6P9EVQ9_JUGRE
EnsemblPlants»
0.0
LOC108991914 LOW QUALITY PROTEIN: guanylyl cyclase 1 Juglans regia
TI:51240 None
     
A0A1Y1INU5_KLENI
EnsemblPlants»
0.0
KFL_007360080 Guanylyl cyclase domain containing protein Klebsormidium nitens
TI:105231 None
   
W5MJC5_LEPOC
Ensembl»
0.0
Guanylyl cyclase domain containing 1 Lepisosteus oculatus
TI:7918 None
   
H9ZE64_MACMU
Ensembl»
0.0
GUCD1 Chromosome 22 open reading frame
13 (Guanylyl cyclase domain containing 1)
Macaca mulatta
TI:9544 None
   
A0A2C9VKQ5_MANES
EnsemblPlants»
0.0
MANES_07G122900 Guanylyl cyclase Manihot esculenta
TI:3983 None
   
A0A2R6XW31_MARPO
EnsemblPlants»
0.0
MARPO_0001s0310 Guanylyl cyclase Marchantia polymorpha
TI:3197 None
   
G7JAJ6_MEDTR
EnsemblPlants»
0.0
11409737 Guanylyl cyclase (Putative
guanylate cyclase (EC 4.6.1.2))
Medicago truncatula
TI:3880 None
 
A0A5F8HLE7_MONDO
Ensembl»
0.0
GUCD1 Guanylyl cyclase domain containing 1 Monodelphis domestica
TI:13616 None
     
GUCD1_MOUSE
Ensembl»
0.0
Gucd1 Protein GUCD1 (Guanylyl cyclase
domain-containing protein 1) (Protein LLN4)
Mus musculus
TI:10090 None
   
A0A804JP65_MUSAM
EnsemblPlants»
0.0
Guanylyl cyclase Musa acuminata
TI:4641 None
     
A0A1U8Q798_NELNU
EnsemblBacteria»
0.0
LOC104601147 Protein GUCD1 isoform X1 Nelumbo nucifera
TI:4432 None
   
A7RM91_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g86655 Protein GUCD1 Nematostella vectensis
TI:45351 None
   
A0A1S3XHT3_TOBAC
EnsemblFungi»
0.0
LOC107765333 Protein GUCD1-like isoform X4 Nicotiana tabacum
TI:4097 None
     
A0A1S4A6D4_TOBAC
EnsemblFungi»
0.0
LOC107794197 Protein GUCD1-like isoform X1 Nicotiana tabacum
TI:4097 None
     
K7E8L5_ORNAN
Ensembl»
0.0
Guanylyl cyclase domain containing 1 Ornithorhynchus anatinus
TI:9258 None
     
Q6I642_ORYSJ
EnsemblPlants»
0.0
Os05g0453500 Os05g0453500 protein Oryza sativa
TI:4530 None
   
H2MLY8_ORYLA
Ensembl»
0.0
gucd1 Guanylyl cyclase domain containing 1 Oryzias latipes
TI:8090 None
     
A0A2I3T318_PANTR
Ensembl»
0.0
GUCD1 Guanylyl cyclase domain containing 1 Pan troglodytes
TI:9598 None
   
A0A2K1IM41_PHYPA
EnsemblPlants»
0.0
PHYPA_026656 Guanylyl cyclase Physcomitrium patens
TI:3218 None
   
A0A7I4FA67_PHYPA
EnsemblPlants»
0.0
Guanylyl cyclase Physcomitrium patens
TI:3218 None
   
B9HHJ1_POPTR
EnsemblPlants»
0.0
POPTR_008G062100 Guanylyl cyclase Populus trichocarpa
TI:3694 None
   
M5X244_PRUPE
EnsemblPlants»
0.0
PRUPE_2G243100 Guanylyl cyclase Prunus persica
TI:3760 None
 
A0A8I5ZSK9_RAT
RGD»
1.6
Gucd1 Guanylyl cyclase domain containing 1 Rattus norvegicus
TI:10116 None
   
B9SE40_RICCO
EnsemblBacteria»
0.0
RCOM_1483470 Protein C22orf13, putative Ricinus communis
TI:3988 None
   
D8RMK6_SELML
EnsemblPlants»
0.0
SELMODRAFT_97002 Guanylyl cyclase Selaginella moellendorffii
TI:88036 None
   
D8SLN8_SELML
EnsemblPlants»
0.0
SELMODRAFT_119770 Guanylyl cyclase Selaginella moellendorffii
TI:88036 None
   
K3Z8T5_SETIT
EnsemblPlants»
0.0
101767961 Guanylyl cyclase Setaria italica
TI:4555 None
 
A0A3Q7G9A7_SOLLC
EnsemblPlants»
0.0
Guanylyl cyclase Solanum lycopersicum
TI:4081 None
     
C5YZ62_SORBI
EnsemblPlants»
0.0
SORBI_3009G159200 Guanylyl cyclase Sorghum bicolor
TI:4558 None
 
A0A7M7P7E3_STRPU
EnsemblMetazoa»
0.0
Protein GUCD1 Strongylocentrotus purpuratus
TI:7668 None
     
A0A7M7RF64_STRPU
EnsemblMetazoa»
0.0
Protein GUCD1 Strongylocentrotus purpuratus
TI:7668 None
     
A0A287B1P5_PIG
Ensembl»
0.0
GUCD1 Guanylyl cyclase domain
containing 1 (Protein GUCD1)
Sus scrofa
TI:9823 None
   
B8C5L3_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_6114 Ubiquitinyl hydrolase 1 Thalassiosira pseudonana
TI:35128 None
   
A0A061FM01_THECC
EnsemblPlants»
0.0
TCM_042643 C22orf13, putative isoform 1 Theobroma cacao
TI:3641 None
 
D2A5H0_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_15537 Protein GUCD1-like Protein Tribolium castaneum
TI:7070 None
   
B3RYX5_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_57249 Guanylyl cyclase Trichoplax adhaerens
TI:10228 None
   
A0A3B5Y3G4_WHEAT
EnsemblPlants»
0.0
Guanylyl cyclase Triticum aestivum
TI:4565 None
     
A0A3B5YZQ4_WHEAT
EnsemblPlants»
0.0
CFC21_007622 Guanylyl cyclase Triticum aestivum
TI:4565 None
   
A0A3B5ZWR3_WHEAT
EnsemblPlants»
0.0
CFC21_012532 Guanylyl cyclase Triticum aestivum
TI:4565 None
   
D7TML6_VITVI
EnsemblPlants»
0.0
VIT_13s0019g02720 Protein GUCD1 Vitis vinifera
TI:29760 None
   
A0A8J0U2K8_XENLA
Xenbase»
0.0
gucd1.S Guanylyl cyclase domain containing
1 S homeolog isoform X1
Xenopus laevis
TI:8355 None
     
A1L3M7_XENLA
Xenbase»
0.0
gucd1.L LOC100037048 protein
(Uncharacterized protein LOC100037048)
Xenopus laevis
TI:8355 None
   
Q28HB1_XENTR
Xenbase»
0.0
gucd1 Novel protein (Protein GUCD1) Xenopus tropicalis
TI:8364 None
   
A0A1D6IXR7_MAIZE
EnsemblPlants»
0.0
103642433 Guanylyl cyclase 1 Zea mays
TI:4577 None
   
A0A804N5P5_MAIZE
EnsemblPlants»
0.0
Guanylyl cyclase 1 Zea mays
TI:4577 None
     
A0A804PCH8_MAIZE
EnsemblPlants»
0.0
eRF1 domain-containing protein Zea mays
TI:4577 None
     
A0A804PTX5_MAIZE
EnsemblPlants»
0.0
Ubiquitin-like protease family
profile domain-containing protein
Zea mays
TI:4577 None
     
B8A1L7_MAIZE
EnsemblPlants»
0.0
ZEAMMB73_Zm00001d038348 Guanylyl cyclase 1 Zea mays
TI:4577 None
   
A0A0K9PU54_ZOSMR
EnsemblPlants»
0.0
ZOSMA_162G00270 Guanylyl cyclase Zostera marina
TI:29655 None