Collated Gene Ontology terms

Biological process: RNA binding(2024) ubiquitin protein ligase activity(2021) transcription coactivator activity(2022)

Molecular function: mRNA processing2024 RNA splicing2024 mRNA splicing, via spliceosome2010, 2013, 2024 negative regulation of gene expression2010 ubiquitin-dependent protein catabolic process2021 translation2021 regulation of metaphase plate congression2014 regulation of cell cycle2024 regulation of RNA splicing2024 protein ubiquitination2021
positive regulation of transcription by RNA polymerase II2022 metamorphosis2013 mRNA cis splicing, via spliceosome2015 female meiosis chromosome segregation2014 alternative mRNA splicing, via spliceosome2019 achiasmate meiosis I2014

Cellular component: nucleus2006, 2009, 2022, 2024 spliceosomal complex2024 cytoplasm2024 nuclear speck2013, 2024 chromatin2013, 2024 U2-type spliceosomal complex2013, 2024 precatalytic spliceosome2010 polytene chromosome2010 nucleoplasm2022 nuclear body2024
membrane2024 mediator complex2022 chromosome2024 catalytic step 2 spliceosome2010

Phylogenetic distribution

Chordates: 3/21 
Echinoderms: 0/0 
Hemichordates: 0/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 13/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 1/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 35/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A022QP80_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a021049mg CWF21 domain-containing protein Erythranthe guttata
TI:4155 None
 
A0A022QPC9_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a001099mg CWF21 domain-containing protein Erythranthe guttata
TI:4155 None
 
A0A022QRD5_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a0233651mg CWF21 domain-containing protein Erythranthe guttata
TI:4155 None
 
A0A061FQT0_THECC
EnsemblPlants»
0.0
TCM_044549 Cwf21 Theobroma cacao
TI:3641 None
 
A0A061FRZ2_THECC
EnsemblPlants»
0.0
TCM_044552 Cwf21 Theobroma cacao
TI:3641 None
 
A0A061FX87_THECC
EnsemblPlants»
0.0
TCM_044534 Uncharacterized protein isoform 1 Theobroma cacao
TI:3641 None
 
A0A067GK28_CITSI
Ensembl»
0.0
CISIN_1g003900mg CWF21 domain-containing protein Citrus sinensis
TI:2711 None
 
A0A072VNT0_MEDTR
EnsemblPlants»
0.0
MTR_1g010100 Pre-mRNA-splicing factor cwc-21, putative Medicago truncatula
TI:3880 None
 
A0A078F4X9_BRANA
EnsemblPlants»
0.0
BnaA06g15740D (rape) hypothetical
protein (BnaA06g15740D protein)		 Brassica napus
TI:3708 None
 
A0A0A0LQ00_CUCSA
EnsemblPlants»
0.0
Csa_2G379180 CWF21 domain-containing protein Cucumis sativus
TI:3659 None
 
A0A0K9PPU0_ZOSMR
EnsemblPlants»
0.0
ZOSMA_189G00490 CWF21 domain-containing protein Zostera marina
TI:29655 None
 
A0A0R0FPC6_SOYBN
EnsemblPlants»
0.0
GLYMA_17G200600 CWF21 domain-containing protein Glycine max
TI:3847 None
 
A0A194YPW1_SORBI
EnsemblPlants»
0.0
SORBI_3004G102000 CWF21 domain-containing protein Sorghum bicolor
TI:4558 None
   
A0A1B6Q4N6_SORBI
EnsemblPlants»
0.0
SORBI_3003G213700 CWF21 domain-containing protein Sorghum bicolor
TI:4558 None
 
A0A1D6DCZ9_WHEAT
EnsemblPlants»
0.0
CAMPLR22A2D_LOCUS4295 CFC21_031385 Genome assembly, chromosome: II Triticum aestivum
TI:4565 None
 
A0A1D6FL01_MAIZE
EnsemblPlants»
0.0
103635373 Cwf21 Zea mays
TI:4577 None
 
A0A1D6QPY2_MAIZE
EnsemblPlants»
0.0
ZEAMMB73_Zm00001d053533 Cwf21 Zea mays
TI:4577 None
 
A0A1D6QPY4_MAIZE
EnsemblPlants»
0.0
ZEAMMB73_Zm00001d053537 Cwf21 Zea mays
TI:4577 None
 
A0A1S3XVU8_TOBAC
EnsemblFungi»
0.0
LOC107769303 Serine/arginine repetitive matrix
protein 2 isoform X1		 Nicotiana tabacum
TI:4097 None
   
A0A1S4DDZ6_TOBAC
EnsemblFungi»
0.0
LOC107828793 Uncharacterized protein DDB_G0290685-like Nicotiana tabacum
TI:4097 None
   
A0A1S4GFQ5_ANOGA
EnsemblMetazoa»
0.0
Uncharacterized protein Anopheles gambiae
TI:7165 None
   
A0A1S4GR31_ANOGA
EnsemblMetazoa»
0.0
CWF21 domain-containing protein Anopheles gambiae
TI:7165 None
 
A0A1U8A3X5_NELNU
EnsemblBacteria»
0.0
LOC104596821 Sarcoplasmic reticulum
histidine-rich calcium-binding protein-like		 Nelumbo nucifera
TI:4432 None
 
A0A1U8BEQ2_NELNU
EnsemblBacteria»
0.0
LOC104612650 Uncharacterized protein LOC104612650 Nelumbo nucifera
TI:4432 None
 
A0A1U8L8N2_GOSHI
Ensembl»
0.0
LOC107923866 Serine/arginine repetitive matrix protein 2-like Gossypium hirsutum
TI:3635 None
   
A0A1U8P671_GOSHI
Ensembl»
0.0
LOC107955360 Protein starmaker-like isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A1U8P9F4_GOSHI
Ensembl»
0.0
LOC107956862 Pre-mRNA-splicing factor CWC21-like Gossypium hirsutum
TI:3635 None
   
A0A1Y1HQH6_KLENI
EnsemblPlants»
0.0
KFL_000650130 CWF21 domain-containing protein Klebsormidium nitens
TI:105231 None
 
A0A251L6V2_MANES
EnsemblPlants»
0.0
MANES_03G046500 CWF21 domain-containing protein Manihot esculenta
TI:3983 None
 
A0A251RDQ2_PRUPE
EnsemblPlants»
0.0
PRUPE_1G463200 CWF21 domain-containing protein Prunus persica
TI:3760 None
 
A0A251TK18_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr10g0299041 Putative mRNA splicing
factor Cwf21 domain-containing protein		 Helianthus annuus
TI:4232 None
 
A0A2A6CX27_PRIPA
EnsemblMetazoa»
0.0
WBGene00274830 Cwf21 domain-containing protein Pristionchus pacificus
TI:54126 None
 
A0A2A6CXN4_PRIPA
EnsemblMetazoa»
0.0
WBGene00282618 SPX domain-containing protein Pristionchus pacificus
TI:54126 None 		 
 
A0A2G3AGG3_CAPAN
EnsemblPlants»
0.0
T459_01199 CWF21 domain-containing protein Capsicum annuum
TI:4072 None
 
A0A2I4EXB7_JUGRE
EnsemblPlants»
0.0
LOC108993535 Serine/arginine repetitive matrix protein 2-like Juglans regia
TI:51240 None
 
A0A2I4GP63_JUGRE
EnsemblPlants»
0.0
LOC109009599 Protein starmaker-like Juglans regia
TI:51240 None
   
A0A2K1KTW1_PHYPA
EnsemblPlants»
0.0
PHYPA_004204 CWF21 domain-containing protein Physcomitrium patens
TI:3218 None
 
A0A2K2A715_POPTR
EnsemblPlants»
0.0
POPTR_006G233000 CWF21 domain-containing protein Populus trichocarpa
TI:3694 None
 
A0A2K3CVN9_CHLRE
EnsemblPlants»
0.0
CHLRE_16g672150v5 RRM domain-containing protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A2K3CW37_CHLRE
EnsemblPlants»
0.0
CHLRE_16g685725v5 SET domain-containing protein Chlamydomonas reinhardtii
TI:3055 None 		 
 
A0A2K3DFH0_CHLRE
EnsemblPlants»
0.0
CHLRE_09g409200v5 CWF21 domain-containing protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A2R6WUA4_MARPO
EnsemblPlants»
0.0
MARPO_0057s0051 CWF21 domain-containing protein Marchantia polymorpha
TI:3197 None
 
A0A2R6WUB9_MARPO
EnsemblPlants»
0.0
MARPO_0057s0059 CWF21 domain-containing protein Marchantia polymorpha
TI:3197 None
 
A0A2R6XFC8_MARPO
EnsemblPlants»
0.0
MARPO_0018s0007 CWF21 domain-containing protein Marchantia polymorpha
TI:3197 None
 
A0A3B3IHN2_ORYLA
Ensembl»
0.0
LOC101162294 Serine/arginine repetitive matrix protein 2 Oryzias latipes
TI:8090 None
   
A0A3B6B5A4_WHEAT
EnsemblPlants»
0.0
CFC21_018661 CWF21 domain-containing protein Triticum aestivum
TI:4565 None
 
A0A3B6CBX8_WHEAT
EnsemblPlants»
0.0
CFC21_025109 CWF21 domain-containing protein Triticum aestivum
TI:4565 None
 
A0A3B6I423_WHEAT
EnsemblPlants»
0.0
CFC21_054457 CWF21 domain-containing protein Triticum aestivum
TI:4565 None
 
A0A3B6LVM0_WHEAT
EnsemblPlants»
0.0
CFC21_074612 CWF21 domain-containing protein Triticum aestivum
TI:4565 None
 
A0A3B6N1D7_WHEAT
EnsemblPlants»
0.0
CFC21_080638 CWF21 domain-containing protein Triticum aestivum
TI:4565 None
 
A0A3Q7HQI0_SOLLC
EnsemblPlants»
0.0
101245685 CWF21 domain-containing protein Solanum lycopersicum
TI:4081 None
   
A0A7I4AK01_PHYPA
EnsemblPlants»
0.0
CWF21 domain-containing protein Physcomitrium patens
TI:3218 None 		 
   
A0A804HVP3_MUSAM
EnsemblPlants»
0.0
GSMUA_302270.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0A804P2V8_MAIZE
EnsemblPlants»
0.0
CWF21 domain-containing protein Zea mays
TI:4577 None
   
A0A804P2V9_MAIZE
EnsemblPlants»
0.0
CWF21 domain-containing protein Zea mays
TI:4577 None
   
A0A804P2W4_MAIZE
EnsemblPlants»
0.0
CWF21 domain-containing protein Zea mays
TI:4577 None
   
A0A804QU61_MAIZE
EnsemblPlants»
0.0
CWF21 domain-containing protein Zea mays
TI:4577 None
   
A0A8I6WHN5_HORVV
EnsemblPlants»
0.0
CWF21 domain-containing protein Hordeum vulgare
TI:4513 None
   
A0A8I7BAC7_HORVV
EnsemblPlants»
0.0
CWF21 domain-containing protein Hordeum vulgare
TI:4513 None
   
A0A8J0SH31_XENTR
CTD»
0.0
son Protein SON Xenopus tropicalis
TI:8364 None
   
A0A9K3HWS3_HELAN
EnsemblPlants»
0.0
HanXRQr2_Chr10g0439271 mRNA splicing factor
Cwf21 domain-containing protein		 Helianthus annuus
TI:4232 None
 
A0A9K3JZ12_HELAN
EnsemblPlants»
0.0
HanXRQr2_Chr01g0037341 mRNA splicing factor
Cwf21 domain-containing protein		 Helianthus annuus
TI:4232 None
 
A0DKG3_PARTE
EnsemblProtists»
0.0
GSPATT00017860001 Chromosome undetermined scaffold_54,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A0E0Y9_PARTE
EnsemblProtists»
0.0
GSPATT00022125001 Chromosome undetermined scaffold_72,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A2FC84_TRIV3
VEuPathDB»
0.0
TVAG_335570 Virulent strain associated lipoprotein, putative Trichomonas vaginalis
TI:5722 None
 
A2FHT1_TRIV3
VEuPathDB»
0.0
TVAG_126710 Uncharacterized protein Trichomonas vaginalis
TI:5722 None
 
A2FUP7_TRIV3
VEuPathDB»
0.0
TVAG_311150 Cell cycle control protein, putative Trichomonas vaginalis
TI:5722 None
 
A7EUE7_SCLS1
VEuPathDB»
0.0
SS1G_08954 CWF21 domain-containing protein Sclerotinia sclerotiorum
TI:5180 None
 
A7RM21_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g86218 CWF21 domain-containing protein Nematostella vectensis
TI:45351 None
 
A8JNI2_DROME
FlyBase»
1.8
Srrm234 Serine-arginine repetitive matrix
2/3/4, isoform F		 Drosophila melanogaster
TI:7227 None
 
A8XYY7_CAEBR
WormBase»
0.0
rsr-2 Protein CBR-RSR-2 Caenorhabditis briggsae
TI:6238 None
 
B3H6J5_ARATH
TAIR»
0.0
At3g49601 Pre-mRNA-splicing factor Arabidopsis thaliana
TI:3702 None
 
B6K894_SCHJY
EnsemblFungi»
0.0
SJAG_05349 Complexed with Cdc5 protein Cwf21 Schizosaccharomyces japonicus
TI:4897 None
 
B6T6E6_MAIZE
EnsemblPlants»
0.0
100276189 Cwf21 Zea mays
TI:4577 None
 
B6UF23_MAIZE
EnsemblPlants»
0.0
100278881 Cwf21 Zea mays
TI:4577 None
 
B7PZH1_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW020192 Pre-mRNA-splicing factor CWC21, putative Ixodes scapularis
TI:6945 None
 
B9RRV5_RICCO
EnsemblBacteria»
0.0
RCOM_0798440 CWF21 domain-containing protein Ricinus communis
TI:3988 None
 
CWC21_ASHGO
EnsemblFungi»
0.0
CWC21 Pre-mRNA-splicing factor CWC21 Ashbya gossypii
TI:33169 None
 
CWC21_ASPFU
EnsemblFungi»
0.0
cwc21 Pre-mRNA-splicing factor cwc21 Aspergillus fumigatus
TI:746128 None
 
CWC21_CANAL
EnsemblFungi»
0.0
CWC21 Pre-mRNA-splicing factor CWC21 Candida albicans
TI:5476 None
 
CWC21_CRYNJ
EnsemblFungi»
0.0
CWC21 Pre-mRNA-splicing factor CWC21 Cryptococcus neoformans
TI:5207 None
 
CWC21_NEUCR
EnsemblFungi»
0.0
cwc-21 Pre-mRNA-splicing factor cwc-21 Neurospora crassa
TI:5141 None
 
CWC21_SCHPO
PomBase»
1.8
cwf21 Pre-mRNA-splicing factor cwf21 (Complexed
with cdc5 protein 21)		 Schizosaccharomyces pombe
TI:4896 None
 
CWC21_YARLI
EnsemblFungi»
0.0
CWC21 Pre-mRNA-splicing factor CWC21 Yarrowia lipolytica
TI:4952 None
 
CWC21_YEAST
SGD»
1.6
CWC21 Pre-mRNA-splicing factor CWC21 (Complexed
with CEF1 protein 21)		 Saccharomyces cerevisiae
TI:4932 None
 
D2A2G4_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_07655 ZAD domain-containing protein Tribolium castaneum
TI:7070 None
   
D6WZL8_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_11813 CWF21 domain-containing protein Tribolium castaneum
TI:7070 None
 
E3KF08_PUCGT
EnsemblFungi»
0.0
PGTG_10008 CWF21 domain-containing protein Puccinia graminis
TI:5297 None
 
E9GK70_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_197118 CWF21 domain-containing protein Daphnia pulex
TI:6669 None
 
F0ZR29_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_80636 CWF21 domain-containing protein Dictyostelium purpureum
TI:5786 None
 
F1QLP6_DANRE
ZFIN»
0.0
zgc:110023 Serine/arginine repetitive matrix 2 Danio rerio
TI:7955 None
 
F4NU85_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_9270 CWF21 domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
F6H2X4_VITVI
EnsemblPlants»
0.0
VIT_04s0008g03130 CWF21 domain-containing protein Vitis vinifera
TI:29760 None
 
H3G6V0_PHYRM
EnsemblProtists»
0.0
CWF21 domain-containing protein Phytophthora ramorum
TI:164328 None
 
H3GQA4_PHYRM
EnsemblProtists»
0.0
CWF21 domain-containing protein Phytophthora ramorum
TI:164328 None
 
I1J1K4_BRADI
EnsemblPlants»
0.0
100822512 CWF21 domain-containing protein Brachypodium distachyon
TI:15368 None
 
K3XS18_SETIT
EnsemblPlants»
0.0
CWF21 domain-containing protein Setaria italica
TI:4555 None
 
K3YQ10_SETIT
EnsemblPlants»
0.0
CWF21 domain-containing protein Setaria italica
TI:4555 None
 
K7M6I8_SOYBN
EnsemblPlants»
0.0
100792927 CWF21 domain-containing protein Glycine max
TI:3847 None
 
K7U6L0_MAIZE
EnsemblPlants»
0.0
103654772 Cwf21 Zea mays
TI:4577 None
 
K7V5J0_MAIZE
EnsemblPlants»
0.0
103654761 Cwf21 Zea mays
TI:4577 None
 
K7V5J4_MAIZE
EnsemblPlants»
0.0
103654766 Cwf21 Zea mays
TI:4577 None
 
M1CW32_SOLTU
EnsemblPlants»
0.0
CWF21 domain-containing protein Solanum tuberosum
TI:4113 None
   
M4DN84_BRACM
EnsemblPlants»
0.0
CWF21 domain-containing protein Brassica campestris
TI:3711 None
   
O46048_DROME
FlyBase»
4.8
east EG:133E12.4 protein (Enhanced adult sensory threshold, isoform
E) (Enhanced adult sensory threshold, isoform F)		 Drosophila melanogaster
TI:7227 None
   
Q54EL3_DICDI
dictyBase»
0.0
DDB_G0291670 CWF21 domain-containing protein Dictyostelium discoideum
TI:44689 None
 
Q54YJ4_DICDI
dictyBase»
1.0
DDB_G0278209 Uncharacterized protein Dictyostelium discoideum
TI:44689 None
 
Q5AYP4_EMENI
EnsemblFungi»
0.0
ANIA_06586 RNA binding protein,
putative (AFU_orthologue AFUA_6G04320)		 Emericella nidulans
TI:162425 None
 
Q7RWE7_NEUCR
EnsemblFungi»
0.0
vad-4 VAD-4 Neurospora crassa
TI:5141 None
 
Q7S4J3_NEUCR
EnsemblFungi»
0.0
NCU08157 2EXR domain-containing protein Neurospora crassa
TI:5141 None 		 
 
Q8IKW9_PLAF7
EnsemblProtists»
0.0
PF3D7_1450700 CWF21 domain-containing protein Plasmodium falciparum
TI:5833 None
 
Q9VWH5_DROME
FlyBase»
0.0
Dmel\CG14200 Uncharacterized protein, isoform A Drosophila melanogaster
TI:7227 None
 
SRRMH_CAEEL
WormBase»
0.0
rsr-2 SRRM2 protein homolog
rsr-2 (SR protein-related rsr-2)		 Caenorhabditis elegans
TI:6239 None
 
T1FZD9_HELRO
EnsemblMetazoa»
0.0
20214187 CWF21 domain-containing protein Helobdella robusta
TI:6412 None
 
W1P0P5_AMBTC
EnsemblPlants»
0.0
AMTR_s00002p00205670 CWF21 domain-containing protein Amborella trichopoda
TI:13333 None
 
W1P2G3_AMBTC
EnsemblPlants»
0.0
AMTR_s00002p00210460 CWF21 domain-containing protein Amborella trichopoda
TI:13333 None