Collated Gene Ontology terms

Biological process: mRNA binding(2018) C2H2 zinc finger domain binding(2009, 2025) RNA binding(2014, 2025) ubiquitin protein ligase activity(2021)

Molecular function: mRNA processing2025 RNA splicing2025 mRNA splicing, via spliceosome2010, 2011, 2013, 2018, 2025 negative regulation of gene expression2010 ubiquitin-dependent protein catabolic process2021 regulation of metaphase plate congression2014 metamorphosis2013 mRNA cis splicing, via spliceosome2024 female meiosis chromosome segregation2014 alternative mRNA splicing, via spliceosome2019
achiasmate meiosis I2014 DNA-templated transcription2025

Cellular component: nucleus2006, 2009, 2022, 2025 spliceosomal complex2025 cytoplasm2025 nuclear speck2013, 2025 catalytic step 2 spliceosome2010, 2011, 2025 chromatin2013, 2025 U2-type precatalytic spliceosome2019, 2025 U2-type catalytic step 2 spliceosome2018, 2025 Cajal body2009, 2025 nucleoplasm2016, 2022
U2-type spliceosomal complex2013 precatalytic spliceosome2010 polytene chromosome2010 nuclear body2025 chromosome2025 Prp19 complex2024

Phylogenetic distribution

Chordates: 6/21 
Echinoderms: 0/0 
Hemichordates: 0/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 1/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q9VWH5_DROME
FlyBase»
0.0
Dmel\CG14200 Uncharacterized protein, isoform A Drosophila melanogaster
TI:7227 None
 
SRRM2_HUMAN
Ensembl»
4.2
SRRM2 Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear
matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)		 Homo sapiens
TI:9606 None
 
F1QLP6_DANRE
ZFIN»
0.0
srrm2 Serine/arginine repetitive matrix 2
(Serine/arginine repetitive matrix protein 2)		 Danio rerio
TI:7955 None
 
A8JNI2_DROME
FlyBase»
1.8
Srrm234 Serine-arginine repetitive matrix
2/3/4, isoform F		 Drosophila melanogaster
TI:7227 None
 
SRRMH_CAEEL
WormBase»
0.0
rsr-2 SRRM2 protein homolog
rsr-2 (SR protein-related rsr-2)		 Caenorhabditis elegans
TI:6239 None
 
CWC21_SCHPO
PomBase»
0.8
cwf21 Pre-mRNA-splicing factor cwf21 (Complexed
with cdc5 protein 21)		 Schizosaccharomyces pombe
TI:4896 None
 
CWC21_YEAST
SGD»
2.2
CWC21 Pre-mRNA-splicing factor CWC21 (Complexed
with CEF1 protein 21)		 Saccharomyces cerevisiae
TI:4932 None
 
B3H6J5_ARATH
TAIR»
0.0
At3g49601 Pre-mRNA-splicing factor Arabidopsis thaliana
TI:3702 None
 
O46048_DROME
FlyBase»
4.8
east EG:133E12.4 protein (Enhanced adult sensory threshold, isoform
E) (Enhanced adult sensory threshold, isoform F)		 Drosophila melanogaster
TI:7227 None
 
Q54EL3_DICDI
dictyBase»
0.0
DDB_G0291670 CWF21 domain-containing protein Dictyostelium discoideum
TI:44689 None