Cluster UKP04265
- HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED
Standard knownness: 4.5; Custom knownness: None; Num. species: 83; Orthology database: Panther19.0; Protein members: 184
Collated Gene Ontology terms
Molecular function: mitochondrial respirasome assembly2012, 2013, 2020, 2024 negative regulation of apoptotic process2012, 2020, 2024 mitochondrial cytochrome c oxidase assembly2013, 2014, 2018, 2024 regulation of proton transport2019, 2024 negative regulation of release of cytochrome c from mitochondria2013, 2024 cellular response to hypoxia2012, 2015 cellular response to glucose starvation2012, 2015 copper ion homeostasis2014
Cellular component: membrane2012, 2024 mitochondrion2009, 2013, 2014, 2018, 2023, 2024 mitochondrial inner membrane2012, 2014, 2016, 2022, 2024 mitochondrial membrane2024 protein-containing complex2010, 2024 nucleoplasm2023, 2024 nucleus2013 plasma membrane2014 endoplasmic reticulum2012 cytoplasm2012
Phylogenetic distribution
| Chordates: | 22/21 |  |
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 3/3 | |
| Arthropods: | 5/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 12/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 2/3 | |
| Excavates: | 0/4 | |
| Harosa: | 1/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 34/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 |
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Proteins
| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Show all] | GO terms | Seq. links | Protein domain links | |||||
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HIG1A_HUMAN Ensembl» |
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HIGD1A | HIG1 domain family member 1A, mitochondrial (Hypoxia-inducible gene 1 protein) (RCF1 homolog A) (RCF1a) |
Homo sapiens TI:9606 None |
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HIG1A_MOUSE Ensembl» |
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Higd1a | HIG1 domain family member 1A, mitochondrial (Hypoxia-inducible gene 1 protein) |
Mus musculus TI:10090 None |
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HIG1B_HUMAN Ensembl» |
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HIGD1B | HIG1 domain family member 1B (Protein CLST 11240) |
Homo sapiens TI:9606 None |
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Q7ZZZ4_DANRE ZFIN» |
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hig1 | HIG1 domain family member 1A (HIG1 hypoxia-inducible domain family, member 1A) (Hypoxia induced gene 1) (Putative growth hormone like protein-1) (Yghl1) |
Danio rerio TI:7955 None |
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HIG2A_MOUSE Ensembl» |
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Higd2a | HIG1 domain family member 2A |
Mus musculus TI:10090 None |
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Q9VXH4_DROME FlyBase» |
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Dmel\CG9921 | RE16337p (Uncharacterized protein, isoform B) (Uncharacterized protein, isoform C) |
Drosophila melanogaster TI:7227 None |
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RCF1_YEAST SGD» |
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RCF1 | Respiratory supercomplex factor 1, mitochondrial (Altered inheritance of mitochondria protein 31) |
Saccharomyces cerevisiae TI:4932 None |
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HIG1A_RAT RGD» |
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Higd1a | HIG1 domain family member 1A, mitochondrial (Hypoxia-inducible gene 1 protein) |
Rattus norvegicus TI:10116 None |
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HIG1B_MOUSE Ensembl» |
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Higd1b | HIG1 domain family member 1B |
Mus musculus TI:10090 None |
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HIG2A_HUMAN Ensembl» |
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HIGD2A | HIG1 domain family member 2A, mitochondrial (RCF1 homolog B) (RCF1b) |
Homo sapiens TI:9606 None |
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HIG2B_HUMAN Ensembl» |
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HIGD2B | Putative HIG1 domain family member 2B (HIG1 domain family member 2B pseudogene) |
Homo sapiens TI:9606 None |
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Q566Y4_DANRE ZFIN» |
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zgc:112385 | HIG1 domain family member 2A, mitochondrial (HIG1 hypoxia-inducible domain family, member 2A) (Zgc:112385) |
Danio rerio TI:7955 None |
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A0A0B4KEI1_DROME FlyBase» |
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Dmel\CG11825 | Uncharacterized protein, isoform C |
Drosophila melanogaster TI:7227 None |
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HIG1C_HUMAN Ensembl» |
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HIGD1C | HIG1 domain family member 1C |
Homo sapiens TI:9606 None |
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HIG1C_MOUSE Ensembl» |
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Higd1c | HIG1 domain family member 1C |
Mus musculus TI:10090 None |
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O01257_CAEEL WormBase» |
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CELE_T20D3.6 T20D3.6 | HIG1 domain-containing protein |
Caenorhabditis elegans TI:6239 None |
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Q21524_CAEEL WormBase» |
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CELE_M05D6.5 M05D6.5 | HIG1 domain-containing protein |
Caenorhabditis elegans TI:6239 None |
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Q54XU9_DICDI dictyBase» |
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DDB_G0278571 | Hypoxia induced family protein |
Dictyostelium discoideum TI:44689 None |
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YL87_SCHPO PomBase» |
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SPAC25B8.07c | HIG1 domain-containing protein C25B8.07c, mitochondrial |
Schizosaccharomyces pombe TI:4896 None |
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A0A8I6AFI4_RAT RGD» |
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LOC100361671 | HIG1 domain family, member 1A-like |
Rattus norvegicus TI:10116 None |
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A0A8V1AA24_CHICK Ensembl» |
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HIGD1C | HIG1 hypoxia inducible domain family member 1C |
Gallus gallus TI:9031 None |
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B2GV65_RAT RGD» |
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Higd2a | HIG1 hypoxia inducible domain family, member 2A |
Rattus norvegicus TI:10116 None |
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D3ZU87_RAT RGD» |
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Higd2al1 | HIG1 hypoxia inducible domain family, member 2A-like 1 |
Rattus norvegicus TI:10116 None |
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F1NUW0_CHICK Ensembl» |
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HIGD2A | Uncharacterized protein |
Gallus gallus TI:9031 None |
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M0RBN7_RAT RGD» |
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Higd1c | HIG1 hypoxia inducible domain family, member 1C |
Rattus norvegicus TI:10116 None |
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