Collated Gene Ontology terms

Biological process: enzyme regulator activity(2013, 2017, 2023, 2025) oxidoreductase activity(2025) cytochrome-c oxidase activity(2005, 2013, 2023, 2025)

Molecular function: mitochondrial electron transport, cytochrome c to oxygen2023, 2024, 2025 oxidative phosphorylation2024 proton transmembrane transport2025 aerobic respiration2013, 2016, 2025 mitochondrial respirasome assembly2013, 2025 cellular respiration2025 generation of precursor metabolites and energy2003 determination of adult lifespan2008

Cellular component: mitochondrial inner membrane2013, 2016, 2024, 2025 respiratory chain complex IV2013, 2019, 2021, 2023, 2024, 2025 mitochondrion2009, 2010, 2014, 2016, 2018, 2021, 2024, 2025 mitochondrial membrane2025 sperm principal piece2025 plasma membrane2014 myelin sheath2014

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 36/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
COX6A_ARATH
TAIR»
1.0
COX6A Cytochrome c oxidase
subunit 6a, mitochondrial (AtCOX6a)		 Arabidopsis thaliana
TI:3702 None
 
CX6A1_HUMAN
Ensembl»
3.1
COX6A1 Cytochrome c oxidase subunit 6A1, mitochondrial (Cytochrome c oxidase
polypeptide VIa-liver) (Cytochrome c oxidase subunit VIA-liver) (COX VIa-L)		 Homo sapiens
TI:9606 None
 
COX13_YEAST
SGD»
5.8
COX13 Cytochrome c oxidase subunit 13,
mitochondrial (Cytochrome c oxidase polypeptide VIa)		 Saccharomyces cerevisiae
TI:4932 None
 
CX6A2_MOUSE
Ensembl»
1.0
Cox6a2 Cytochrome c oxidase subunit 6A2, mitochondrial
(Cytochrome c oxidase polypeptide VIa-heart) (COXVIAH)		 Mus musculus
TI:10090 None
 
Q66I77_DANRE
ZFIN»
1.0
cox6a2 Cytochrome c oxidase subunit
(Cytochrome c oxidase polypeptide VIa)		 Danio rerio
TI:7955 None
 
Q9VVU8_DROME
FlyBase»
1.6
COX6AL2 Cytochrome c oxidase subunit 6A-like 2, isoform B (Cytochrome
c oxidase subunit 6A-like 2, isoform C) (IP09469p1) (IP13061p1)		 Drosophila melanogaster
TI:7227 None
 
CX6A2_HUMAN
Ensembl»
1.9
COX6A2 Cytochrome c oxidase subunit 6A2, mitochondrial (Cytochrome c oxidase
polypeptide VIa-heart) (COXVIAH) (Cytochrome c oxidase subunit VIA-muscle) (COX VIa-M)		 Homo sapiens
TI:9606 None
 
Q4QPY7_DROME
FlyBase»
2.1
COX6AL Cytochrome c oxidase
subunit 6A-like (GEO12072p1) (IP05686p)		 Drosophila melanogaster
TI:7227 None
 
Q9W1N3_DROME
FlyBase»
5.0
levy Levy, isoform A (Levy, isoform B) (RH03295p) Drosophila melanogaster
TI:7227 None
 
CX6A1_MOUSE
Ensembl»
1.0
Cox6a1 Cytochrome c oxidase subunit 6A1,
mitochondrial (Cytochrome c oxidase polypeptide VIa-liver)		 Mus musculus
TI:10090 None
 
CX6A1_RAT
RGD»
1.0
Cox6a1 Cytochrome c oxidase subunit 6A1,
mitochondrial (Cytochrome c oxidase polypeptide VIa-liver)		 Rattus norvegicus
TI:10116 None
 
COX13_SCHPO
PomBase»
3.0
cox13 Cytochrome c oxidase subunit 13,
mitochondrial (Cytochrome c oxidase polypeptide VIa)		 Schizosaccharomyces pombe
TI:4896 None
 
COX6A_CAEEL
WormBase»
1.0
cox-6A Cytochrome c oxidase subunit 6A,
mitochondrial (Cytochrome c oxidase polypeptide VIa)		 Caenorhabditis elegans
TI:6239 None
 
CX6A2_RAT
RGD»
1.9
Cox6a2 Cytochrome c oxidase subunit 6A2, mitochondrial
(Cytochrome c oxidase polypeptide VIa-heart) (COXVIAH)		 Rattus norvegicus
TI:10116 None
 
A0A3Q3AUQ1_CHICK
Ensembl»
1.0
Cytochrome c oxidase subunit
(Cytochrome c oxidase polypeptide VIa)		 Gallus gallus
TI:9031 None
   
A0A8V0ZC01_CHICK
Ensembl»
1.0
COX6A1 Cytochrome c oxidase subunit
(Cytochrome c oxidase polypeptide VIa)		 Gallus gallus
TI:9031 None