Collated Gene Ontology terms

Biological process: enzyme regulator activity(2019, 2022, 2025) calcium channel inhibitor activity(2023)

Molecular function: tRNA nucleoside ribose methylation2022, 2025 tRNA processing2025 negative regulation of endoplasmic reticulum calcium ion concentration2017, 2025 tRNA methylation2019, 2022, 2025 lipid homeostasis2023, 2025 wobble position ribose methylation2019 adaptive thermogenesis2017 type B pancreatic cell development2017 regulation of TOR signaling2018 pancreas regeneration2017
negative regulation of lipid storage2023 endocrine pancreas development2017 cold acclimation2018

Cellular component: endoplasmic reticulum2025 cytosol2009, 2025 cytoplasm2017, 2018, 2025 nucleoplasm2017, 2025 nucleus2009, 2025 cytoplasmic side of endoplasmic reticulum membrane2023 plasma membrane2022 chloroplast2018

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 3/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
THADA_MOUSE
Ensembl»
4.5
Thada tRNA (32-2'-O)-methyltransferase regulator THADA
(Thyroid adenoma-associated protein homolog)		 Mus musculus
TI:10090 None
 
THADA_DROME
FlyBase»
5.2
THADA tRNA (32-2'-O)-methyltransferase regulator THADA
(Thyroid adenoma-associated protein homolog)		 Drosophila melanogaster
TI:7227 None
 
THADA_HUMAN
Ensembl»
6.0
THADA tRNA (32-2'-O)-methyltransferase regulator THADA (Gene inducing
thyroid adenomas protein) (Thyroid adenoma-associated protein)		 Homo sapiens
TI:9606 None
 
THADA_SCHPO
PomBase»
3.1
trm732 tRNA (32-2'-O)-methyltransferase
regulator trm732		 Schizosaccharomyces pombe
TI:4896 None
 
A0A8V0ZE55_CHICK
Ensembl»
1.5
THADA tRNA (32-2'-O)-methyltransferase regulator THADA Gallus gallus
TI:9031 None
   
THADA_YEAST
SGD»
3.4
TRM732 tRNA (32-2'-O)-methyltransferase
regulator TRM732		 Saccharomyces cerevisiae
TI:4932 None
 
A0ABK0L617_RAT
RGD»
2.5
Thada tRNA (32-2'-O)-methyltransferase regulator THADA Rattus norvegicus
TI:10116 None
   
F4JFA0_ARATH
TAIR»
2.6
THADA Thyroid adenoma-associated-like protein Arabidopsis thaliana
TI:3702 None
 
THADA_CHICK
CTD»
2.0
THADA tRNA (32-2'-O)-methyltransferase regulator THADA
(Thyroid adenoma-associated protein homolog)		 Gallus gallus
TI:9031 None
 
W6RTG0_CAEEL
WormBase»
1.5
CELE_Y92H12A.5 Y92H12A.5 tRNA (32-2'-O)-methyltransferase regulator THADA Caenorhabditis elegans
TI:6239 None
 
A0A8M2BCI6_DANRE
ZFIN»
1.0
si:ch211-225b11.4 tRNA (32-2'-O)-methyltransferase regulator
THADA isoform X1		 Danio rerio
TI:7955 None
   
A0A8V1A2N0_CHICK
Ensembl»
1.0
LOC416924 DUF2428 domain-containing protein Gallus gallus
TI:9031 None
   
Q553Q9_DICDI
dictyBase»
1.0
DDB_G0275399 Uncharacterized protein Dictyostelium discoideum
TI:44689 None
 
Q5BLB0_DANRE
ZFIN»
2.4
thada Thyroid adenoma-associated protein (Zgc:113068) Danio rerio
TI:7955 None
 
Q9VB48_DROME
FlyBase»
1.0
SD09067p DUF2428 domain-containing protein Drosophila melanogaster
TI:7227 None