Collated Gene Ontology terms

Biological process: RNA binding(2025) nucleic acid binding(2025) ligase activity(2025)

Molecular function: DNA alkylation repair2024, 2025 regulation of DNA-templated transcription2009, 2021, 2025 DNA-templated transcription2025 DNA repair2025 DNA damage response2025 regulation of gene expression2025 thigmotaxis2016 rescue of stalled ribosome2024 neuromuscular junction development2016 myotome development2016
axonogenesis2016 DNA replication2024

Cellular component: nucleus2009, 2016, 2021, 2024, 2025 nuclear speck2025 transcription regulator complex2009, 2025 cytoplasm2009, 2018, 2025 chloroplast2018 nucleoplasm2014 mitochondrion2021 cytosol2009 DNA repair complex2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 8/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 1/3 
Excavates: 3/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
H2Q224_PANTR
Ensembl»
0.0
ASCC1 Activating signal cointegrator 1 complex subunit 1
(ASC-1 complex subunit p50) (Trip4 complex subunit p50)		 Pan troglodytes
TI:9598 None
 
ASCC1_HUMAN
Ensembl»
2.5
ASCC1 Activating signal cointegrator 1 complex subunit 1
(ASC-1 complex subunit p50) (Trip4 complex subunit p50)		 Homo sapiens
TI:9606 None
 
A0A2I2YDF6_GORGO
Ensembl»
0.0
ASCC1 Activating signal cointegrator 1 complex subunit 1
(ASC-1 complex subunit p50) (Trip4 complex subunit p50)		 Gorilla gorilla
TI:9593 None
 
ASCC1_MOUSE
Ensembl»
1.0
Ascc1 Activating signal cointegrator 1 complex subunit 1
(ASC-1 complex subunit p50) (Trip4 complex subunit p50)		 Mus musculus
TI:10090 None
 
F4J1H2_ARATH
TAIR»
0.5
At3g16230 Eukaryotic LigT Arabidopsis thaliana
TI:3702 None
 
I0FS71_MACMU
Ensembl»
0.0
ASCC1 Activating signal cointegrator 1 complex subunit 1
(ASC-1 complex subunit p50) (Trip4 complex subunit p50)		 Macaca mulatta
TI:9544 None
 
A0A072VD69_MEDTR
EnsemblPlants»
0.0
11420973 AKAP7 2'5' RNA ligase-like domain protein
(Putative K domain, RNA ligase/cyclic nucleotide phosphodiesterase)		 Medicago truncatula
TI:3880 None
 
B7PGT3_IXOSC
EnsemblMetazoa»
0.0
8028740 Activating signal cointegrator
1 complex subunit, putative		 Ixodes scapularis
TI:6945 None
 
Q580Y1_TRYB2
TubercuList»
0.0
Tb08.10J17.830 A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Trypanosoma brucei
TI:5691 None
 
Q6NKQ6_ARATH
TAIR»
0.5
At3g16220 At3g16220 (Eukaryotic LigT) Arabidopsis thaliana
TI:3702 None
 
Q7JW66_DROME
FlyBase»
0.5
cg12129 LD21545p Drosophila melanogaster
TI:7227 None
 
T1G276_HELRO
EnsemblMetazoa»
0.0
20215174 K Homology domain-containing protein Helobdella robusta
TI:6412 None
 
A0A022Q4Q5_ERYGU
neXtProt»
0.0
MIMGU_mgv1a004915mg K Homology domain-containing protein Erythranthe guttata
TI:4155 None
 
A0A061GCI2_THECC
neXtProt»
0.0
TCM_028835 Eukaryotic LigT isoform 1 Theobroma cacao
TI:3641 None
 
A0A067ESS7_CITSI
neXtProt»
0.0
CISIN_1g010205mg K Homology domain-containing protein Citrus sinensis
TI:2711 None
 
A0A072TQ81_MEDTR
EnsemblPlants»
0.0
MTR_8g033020 AKAP7 2'5' RNA ligase-like domain protein Medicago truncatula
TI:3880 None
 
A0A078G473_BRANA
euHCVdb»
0.0
BnaA01g28130D BnaA01g28130D protein Brassica napus
TI:3708 None
 
A0A078J9D5_BRANA
euHCVdb»
0.0
BnaC01g44570D BnaC01g44570D protein Brassica napus
TI:3708 None
 
A0A078JTR5_BRANA
euHCVdb»
0.0
BnaCnng67220D BnaCnng67220D protein Brassica napus
TI:3708 None
 
A0A0A0K963_CUCSA
euHCVdb»
0.0
Csa_7G447090 K Homology domain-containing protein Cucumis sativus
TI:3659 None
 
A0A0K9PRQ2_ZOSMR
euHCVdb»
0.0
ZOSMA_178G00340 K Homology domain-containing protein Zostera marina
TI:29655 None
 
A0A0P0V044_ORYSJ
euHCVdb»
0.0
Os01g0231800 Os01g0231800 protein Oryza sativa
TI:4530 None
 
A0A0Q3IBZ5_BRADI
EnsemblPlants»
0.0
LOC100837554 K Homology domain-containing protein Brachypodium distachyon
TI:15368 None
 
A0A0R0H963_SOYBN
EnsemblPlants»
0.0
GLYMA_13G355900 A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Glycine max
TI:3847 None
 
A0A1U8FY68_CAPAN
neXtProt»
0.0
T459_07007 A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Capsicum annuum
TI:4072 None
 
A0A1W0VVA7_SORBI
euHCVdb»
0.0
SORBI_3003G007300 K Homology domain-containing protein Sorghum bicolor
TI:4558 None
 
A0A251PW97_PRUPE
euHCVdb»
0.0
PRUPE_3G063900 K Homology domain-containing protein Prunus persica
TI:3760 None
 
A0A251UUS7_HELAN
euHCVdb»
0.0
HannXRQ_Chr04g0096261 Putative eukaryotic LigT Helianthus annuus
TI:4232 None
 
A0A251UVN3_HELAN
euHCVdb»
0.0
HannXRQ_Chr04g0096271 Putative RNA
ligase/cyclic nucleotide phosphodiesterase		 Helianthus annuus
TI:4232 None
 
A0A2G3A3I6_CAPAN
euHCVdb»
0.0
T459_10903 K Homology domain-containing protein Capsicum annuum
TI:4072 None
 
A0A2K2BZX0_POPTR
euHCVdb»
0.0
POPTR_001G186600 K Homology domain-containing protein Populus trichocarpa
TI:3694 None
 
A0A2K3E570_CHLRE
euHCVdb»
0.0
CHLRE_01g008000v5 K Homology domain-containing protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A2R6WCG2_MARPO
euHCVdb»
0.0
MARPO_0110s0022 K Homology domain-containing protein Marchantia polymorpha
TI:3197 None
 
A0A3N7G1W8_POPTR
euHCVdb»
0.0
POPTR_003G051001 A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Populus trichocarpa
TI:3694 None
 
A0A7I4F621_PHYPA
EnsemblPlants»
0.0
LOC112293507 K Homology domain-containing protein Physcomitrium patens
TI:3218 None
 
A0A7U2EWR4_PHANO
TubercuList»
0.0
JI435_075120 A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Phaeosphaeria nodorum
TI:13684 None
 
A0A804KZ07_MUSAM
EnsemblPlants»
0.0
GSMUA_325070.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0A9K3J3C1_HELAN
euHCVdb»
0.0
HanXRQr2_Chr04g0140981 A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Helianthus annuus
TI:4232 None
 
A0A9K3J421_HELAN
neXtProt»
0.0
HanXRQr2_Chr04g0140991 K Homology domain-containing protein Helianthus annuus
TI:4232 None
 
A0A9K3J4D2_HELAN
euHCVdb»
0.0
HanXRQr2_Chr04g0140971 A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Helianthus annuus
TI:4232 None
 
A0A9R1WCM0_LACSA
neXtProt»
0.0
LSAT_V11C100014790 K Homology domain-containing protein Lactuca sativa
TI:4236 None
 
A0BLR8_PARTE
euHCVdb»
0.0
GSPATT00030119001 A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Paramecium tetraurelia
TI:5888 None
 
A2DZ35_TRIV3
TubercuList»
0.0
TVAG_026320 KH domain containing protein Trichomonas vaginalis
TI:5722 None
 
A4II84_XENTR
Xenbase»
0.0
ascc1 Activating signal cointegrator 1
complex subunit 1 (LOC100124965 protein)		 Xenopus tropicalis
TI:8364 None
 
A7EYH7_SCLS1
TubercuList»
0.0
SS1G_10393 A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Sclerotinia sclerotiorum
TI:5180 None
 
A7T2D7_NEMVE
neXtProt»
0.0
NEMVEDRAFT_v1g142990 K Homology domain-containing protein Nematostella vectensis
TI:45351 None
 
A7UR96_ANOGA
EnsemblMetazoa»
0.0
1269658 AGAP007571-PA (KH domain-containing protein) Anopheles gambiae
TI:7165 None
 
A8X3Y6_CAEBR
WormBase»
0.0
ascc-1 Protein CBG06998 Caenorhabditis briggsae
TI:6238 None
 
A9V0H3_MONBE
euHCVdb»
0.0
MONBRDRAFT_32586 Uncharacterized protein Monosiga brevicollis
TI:81824 None
 
A9Z1L6_CAEEL
WormBase»
0.5
ascc-1 K Homology domain-containing protein Caenorhabditis elegans
TI:6239 None
 
B3RIW8_TRIAD
CTD»
0.0
TRIADDRAFT_19563 K Homology domain-containing protein Trichoplax adhaerens
TI:10228 None
 
B6K3C2_SCHJY
TubercuList»
0.0
SJAG_03106 A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Schizosaccharomyces japonicus
TI:4897 None
 
B9RQI1_RICCO
neXtProt»
0.0
RCOM_1492510 Nucleic acid binding protein, putative Ricinus communis
TI:3988 None
 
C3YXH6_BRAFL
neXtProt»
0.0
LOC118427818 Activating signal cointegrator
1 complex subunit 1-like		 Branchiostoma floridae
TI:7739 None
 
C4M534_ENTH1
TubercuList»
0.0
EHI_128160 Activating signal cointegrator 1
complex subunit 1, putative		 Entamoeba histolytica
TI:5759 None
 
C5XJM9_SORBI
euHCVdb»
0.0
SORBI_3003G006833 K Homology domain-containing protein Sorghum bicolor
TI:4558 None
 
C8VL63_EMENI
TubercuList»
0.0
ANIA_01987 A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Emericella nidulans
TI:162425 None
 
D6WJR9_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_14791 Activating signal cointegrator 1
complex subunit 1-like Protein		 Tribolium castaneum
TI:7070 None
 
D6WLY4_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_13370 Activating signal cointegrator 1
complex subunit 1-like Protein		 Tribolium castaneum
TI:7070 None
 
D8R984_SELML
euHCVdb»
0.0
SELMODRAFT_88393 A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Selaginella moellendorffii
TI:88036 None
 
D8T9Z4_SELML
neXtProt»
0.0
SELMODRAFT_135207 A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Selaginella moellendorffii
TI:88036 None
 
F6HYD3_VITVI
neXtProt»
0.0
VIT_09s0002g04060 K Homology domain-containing protein Vitis vinifera
TI:29760 None
 
K3XIH4_SETIT
EnsemblPlants»
0.0
K Homology domain-containing protein Setaria italica
TI:4555 None
 
K7M914_SOYBN
EnsemblPlants»
0.0
LOC100785531 K Homology domain-containing protein Glycine max
TI:3847 None
 
Q1K4Q6_NEUCR
TubercuList»
0.0
NCU01490 A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Neurospora crassa
TI:5141 None
 
Q4QAM7_LEIMA
TubercuList»
0.0
LMJF_24_1060 A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Leishmania major
TI:5664 None
 
Q4WPU6_ASPFU
TubercuList»
0.0
AFUA_4G10500 A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Aspergillus fumigatus
TI:746128 None
 
Q566X5_DANRE
ZFIN»
3.7
ascc1 Activating signal cointegrator 1
complex subunit 1 (Zgc:112403)		 Danio rerio
TI:7955 None
 
Q5NB67_ORYSJ
euHCVdb»
0.0
Os01g0231900 Os01g0231900 protein Oryza sativa
TI:4530 None
 
W1NSQ1_AMBTC
euHCVdb»
0.0
AMTR_s00109p00141330 K Homology domain-containing protein Amborella trichopoda
TI:13333 None
 
W1NU13_AMBTC
neXtProt»
0.0
AMTR_s00109p00142690 A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Amborella trichopoda
TI:13333 None
 
W1NVL7_AMBTC
euHCVdb»
0.0
AMTR_s00109p00142250 A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Amborella trichopoda
TI:13333 None
 
W5MD86_LEPOC
Ensembl»
0.0
Activating signal cointegrator
1 complex subunit 1		 Lepisosteus oculatus
TI:7918 None
 
YOGD_SCHPO
PomBase»
0.9
SPBC15D4.13c Uncharacterized protein C15D4.13c Schizosaccharomyces pombe
TI:4896 None
 
A0A1D5PKQ5_CHICK
Ensembl»
0.0
ASCC1 Activating signal cointegrator
1 complex subunit 1		 Gallus gallus
TI:9031 None
   
A0A1L8FJW1_XENLA
Xenbase»
0.0
ascc1.L Activating signal cointegrator
1 complex subunit 1		 Xenopus laevis
TI:8355 None
   
A0A1S4ASZ3_TOBAC
euHCVdb»
0.0
LOC107801051 Heterogeneous nuclear ribonucleoprotein
87F-like isoform X1		 Nicotiana tabacum
TI:4097 None
   
A0A1S4AY71_TOBAC
euHCVdb»
0.0
LOC107802500 Uncharacterized protein LOC107802500 isoform
X1 (Uncharacterized protein isoform X1)		 Nicotiana tabacum
TI:4097 None
   
A0A1S4BY41_TOBAC
euHCVdb»
0.0
LOC107813118 Uncharacterized protein isoform X1 Nicotiana tabacum
TI:4097 None
   
A0A1U7ZQ47_NELNU
euHCVdb»
0.0
LOC104595133 Uncharacterized protein LOC104595133 isoform X1 Nelumbo nucifera
TI:4432 None
   
A0A1U8HSF9_GOSHI
euHCVdb»
0.0
LOC107889109 Uncharacterized protein LOC107889109
(Uncharacterized protein isoform X1)		 Gossypium hirsutum
TI:3635 None
   
A0A1U8NSY9_GOSHI
euHCVdb»
0.0
LOC107950695 Uncharacterized protein isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A287BL96_PIG
Ensembl»
0.0
ASCC1 Activating signal cointegrator 1 complex subunit 1
(ASC-1 complex subunit p50) (Trip4 complex subunit p50)		 Sus scrofa
TI:9823 None
   
A0A2A6CFW4_PRIPA
EnsemblMetazoa»
0.0
WBGene00114118 K Homology domain containing protein Pristionchus pacificus
TI:54126 None
   
A0A2I4DQ78_JUGRE
neXtProt»
0.0
LOC108982388 Uncharacterized protein LOC108982388 isoform X1 Juglans regia
TI:51240 None
   
A0A3B6EDQ0_WHEAT
EnsemblPlants»
0.0
LOC123060803 K Homology domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6ENZ4_WHEAT
EnsemblPlants»
0.0
Uncharacterized protein Triticum aestivum
TI:4565 None
   
A0A3B6FNP5_WHEAT
EnsemblPlants»
0.0
LOC123069365 K Homology domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6GQM2_WHEAT
EnsemblPlants»
0.0
LOC123077882 K Homology domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3Q7FAK3_SOLLC
EnsemblPlants»
0.0
A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Solanum lycopersicum
TI:4081 None
   
A0A3Q7FVH8_SOLLC
EnsemblPlants»
0.0
LOC101268850 K Homology domain-containing protein Solanum lycopersicum
TI:4081 None
   
A0A5F8GYB5_MONDO
Ensembl»
0.0
ASCC1 Activating signal cointegrator
1 complex subunit 1		 Monodelphis domestica
TI:13616 None
   
A0A7M7NKB1_STRPU
EnsemblMetazoa»
0.0
K Homology domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A803T930_ANOCA
Ensembl»
0.0
ASCC1 Activating signal cointegrator
1 complex subunit 1		 Anolis carolinensis
TI:28377 None
   
A0A804MXK1_MAIZE
EnsemblPlants»
0.0
LOC103649543 A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Zea mays
TI:4577 None
   
A0A8I3RS67_CANLF
Ensembl»
0.0
ASCC1 Activating signal cointegrator 1 complex subunit 1
(ASC-1 complex subunit p50) (Trip4 complex subunit p50)		 Canis lupus
TI:9612 None
   
A0A8I5ZMZ0_RAT
RGD»
0.0
Ascc1 Activating signal cointegrator 1 complex subunit 1
(ASC-1 complex subunit p50) (Trip4 complex subunit p50)		 Rattus norvegicus
TI:10116 None
   
A0A8I7B9K4_HORVV
EnsemblPlants»
0.0
LOC123443263 K Homology domain-containing protein Hordeum vulgare
TI:4513 None
   
A0A9L0SP54_HORSE
Ensembl»
0.0
ASCC1 Activating signal cointegrator 1 complex subunit 1
(ASC-1 complex subunit p50) (Trip4 complex subunit p50)		 Equus caballus
TI:9796 None
   
A0AAA9S3D4_BOVIN
Ensembl»
0.0
ASCC1 Activating signal cointegrator 1 complex subunit 1
(ASC-1 complex subunit p50) (Trip4 complex subunit p50)		 Bos taurus
TI:9913 None
   
A0ABI7XX66_FELCA
Ensembl»
0.0
ASCC1 K Homology domain-containing protein Felis catus
TI:9685 None
   
A0ABM3ANK1_GOSHI
neXtProt»
0.0
LOC107891710 Uncharacterized protein isoform X3 Gossypium hirsutum
TI:3635 None
   
A0ABM3RUG4_SPIOL
neXtProt»
0.0
LOC110801732 A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Spinacia oleracea
TI:3562 None
   
F6TWG2_ORNAN
Ensembl»
0.0
ASCC1 Activating signal cointegrator
1 complex subunit 1		 Ornithorhynchus anatinus
TI:9258 None
   
F6YCI4_CIOIN
Ensembl»
0.0
LOC100175172 Activating signal cointegrator
1 complex subunit 1-like		 Ciona intestinalis
TI:7719 None
   
H2LZC4_ORYLA
Ensembl»
0.0
ASCC1 Activating signal cointegrator
1 complex subunit 1		 Oryzias latipes
TI:8090 None
   
M0ZM09_SOLTU
EnsemblPlants»
0.0
Nucleic acid binding protein Solanum tuberosum
TI:4113 None
   
M0ZRK2_SOLTU
EnsemblPlants»
0.0
Nucleic acid binding protein Solanum tuberosum
TI:4113 None
   
M4DXC4_BRACM
EnsemblPlants»
0.0
A-kinase anchor protein
7-like phosphoesterase domain-containing protein		 Brassica campestris
TI:3711 None