Collated Gene Ontology terms

Biological process: transferase activity(2025) protein-macromolecule adaptor activity(2018)

Molecular function: protein maturation2018, 2025 ribosomal large subunit biogenesis2018, 2025 translational initiation2018, 2025 telomere maintenance2025

Cellular component: nucleus2009, 2013, 2018, 2025 cytoplasm2018, 2025 Yae1-Lto1 complex2018 extracellular region2018 cytosolic [4Fe-4S] assembly targeting complex2018 cytosol2009

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 1/3 
Arthropods: 3/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 36/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
LTO1_YEAST
SGD»
3.2
LTO1 Protein LTO1 (LTO1 family protein YNL260C) Saccharomyces cerevisiae
TI:4932 None
 
LTO1_HUMAN
Ensembl»
2.9
LTO1 Protein LTO1 homolog (Oral cancer-overexpressed protein
1) (Tumor-amplified and overexpressed sequence 1)		 Homo sapiens
TI:9606 None
 
LTO1_MOUSE
Ensembl»
2.0
Lto1 Protein LTO1 homolog (Oral
cancer-overexpressed protein 1 homolog)		 Mus musculus
TI:10090 None
 
LTO1_DICDI
dictyBase»
1.5
DDB_G0272178 Protein LTO1 homolog Dictyostelium discoideum
TI:44689 None
 
LTO1_SCHPO
PomBase»
1.5
SPCC191.08 LTO1 family protein C191.08 Schizosaccharomyces pombe
TI:4896 None
 
A0A8I6A2Q3_RAT
RGD»
0.5
Lto1 LTO1 maturation factor of ABCE1 Rattus norvegicus
TI:10116 None
   
A0A022RXC8_ERYGU
neXtProt»
0.0
MIMGU_mgv1a016019mg Essential protein Yae1
N-terminal domain-containing protein		 Erythranthe guttata
TI:4155 None 		 
 
A0A061EAM8_THECC
euHCVdb»
0.0
TCM_007965 Transferases,folic acid binding Theobroma cacao
TI:3641 None
 
A0A067DLR8_CITSI
euHCVdb»
0.0
CISIN_1g048659mg Essential protein Yae1
N-terminal domain-containing protein		 Citrus sinensis
TI:2711 None 		 
 
A0A067DXD7_CITSI
euHCVdb»
0.0
CISIN_1g034369mg Essential protein Yae1
N-terminal domain-containing protein		 Citrus sinensis
TI:2711 None 		 
 
A0A072ULD5_MEDTR
EnsemblPlants»
0.0
MTR_4g065010 Oral cancer overexpressed protein
(Putative essential protein Yae1)		 Medicago truncatula
TI:3880 None 		 
 
A0A0A0KE52_CUCSA
euHCVdb»
0.0
Csa_6G124070 Essential protein Yae1
N-terminal domain-containing protein		 Cucumis sativus
TI:3659 None 		 
 
A0A0K9P2X9_ZOSMR
euHCVdb»
0.0
ZOSMA_415G00080 Oral cancer overexpressed protein 1 Zostera marina
TI:29655 None 		 
 
A0A0Q3HE08_BRADI
EnsemblPlants»
0.0
LOC100827336 Uncharacterized protein Brachypodium distachyon
TI:15368 None 		 
 
A0A1D8PTD6_CANAL
CGD»
0.0
CAALFM_CR06980WA orf19.9903 Ribosome biosynthesis protein Candida albicans
TI:5476 None 		 
 
A0A1S3ZMD0_TOBAC
euHCVdb»
0.0
LOC107788360 Oral cancer-overexpressed protein 1 homolog Nicotiana tabacum
TI:4097 None 		     
A0A1U8BMT6_NELNU
euHCVdb»
0.0
LOC104612594 Oral cancer-overexpressed protein 1 homolog Nelumbo nucifera
TI:4432 None 		     
A0A1U8GR94_CAPAN
neXtProt»
0.0
T459_15434 Essential protein Yae1
N-terminal domain-containing protein		 Capsicum annuum
TI:4072 None 		 
 
A0A1Y1HUF7_KLENI
euHCVdb»
0.0
KFL_000630120 Essential protein Yae1
N-terminal domain-containing protein		 Klebsormidium nitens
TI:105231 None 		 
 
A0A251TEX8_HELAN
neXtProt»
0.0
ORAV1 Essential protein Yae1
(Putative ORAV1-like protein)		 Helianthus annuus
TI:4232 None 		 
 
A0A251TZZ8_HELAN
euHCVdb»
0.0
HannXRQ_Chr09g0274351 Putative essential protein Yae1 Helianthus annuus
TI:4232 None 		 
 
A0A251UG28_HELAN
euHCVdb»
0.0
HannXRQ_Chr06g0167021 Putative essential protein Yae1 Helianthus annuus
TI:4232 None 		 
 
A0A287GHP0_HORVV
EnsemblPlants»
0.0
Essential protein Yae1
N-terminal domain-containing protein		 Hordeum vulgare
TI:4513 None 		     
A0A287HVV0_HORVV
EnsemblPlants»
0.0
LOC123425841 Essential protein Yae1
N-terminal domain-containing protein		 Hordeum vulgare
TI:4513 None 		     
A0A287MHZ8_HORVV
EnsemblPlants»
0.0
LOC123440873 Essential protein Yae1
N-terminal domain-containing protein		 Hordeum vulgare
TI:4513 None 		     
A0A2A6B2P2_PRIPA
EnsemblMetazoa»
0.0
WBGene00113096 Uncharacterized protein Pristionchus pacificus
TI:54126 None 		     
A0A2C9VLU5_MANES
euHCVdb»
0.0
MANES_06G013500v8 Essential protein Yae1
N-terminal domain-containing protein		 Manihot esculenta
TI:3983 None 		 
 
A0A2G2ZJZ2_CAPAN
neXtProt»
0.0
T459_15327 Essential protein Yae1
N-terminal domain-containing protein		 Capsicum annuum
TI:4072 None 		 
 
A0A2I4GX98_JUGRE
euHCVdb»
0.0
LOC109011675 Protein LTO1 homolog Juglans regia
TI:51240 None 		     
A0A2K1KFZ8_PHYPA
EnsemblPlants»
0.0
LOC112283913 Essential protein Yae1
N-terminal domain-containing protein		 Physcomitrium patens
TI:3218 None 		 
 
A0A2K1Y5R4_POPTR
neXtProt»
0.0
POPTR_013G145800 Essential protein Yae1
N-terminal domain-containing protein		 Populus trichocarpa
TI:3694 None 		 
 
A0A2R6WNP6_MARPO
euHCVdb»
0.0
MARPO_0071s0092 Essential protein Yae1
N-terminal domain-containing protein		 Marchantia polymorpha
TI:3197 None 		 
 
A0A3B3I0D8_ORYLA
Ensembl»
0.0
lto1 LTO1 maturation factor of ABCE1 Oryzias latipes
TI:8090 None 		     
A0A3B3I7T7_ORYLA
Ensembl»
0.0
Uncharacterized protein Oryzias latipes
TI:8090 None 		     
A0A3B6AVK8_WHEAT
EnsemblPlants»
0.0
LOC123188401 Essential protein Yae1
N-terminal domain-containing protein		 Triticum aestivum
TI:4565 None 		     
A0A3B6C469_WHEAT
EnsemblPlants»
0.0
LOC123044643 Essential protein Yae1
N-terminal domain-containing protein		 Triticum aestivum
TI:4565 None 		     
A0A3B6ES14_WHEAT
EnsemblPlants»
0.0
LOC123059286 Essential protein Yae1
N-terminal domain-containing protein		 Triticum aestivum
TI:4565 None 		     
A0A3B6H205_WHEAT
EnsemblPlants»
0.0
LOC123075542 Essential protein Yae1
N-terminal domain-containing protein		 Triticum aestivum
TI:4565 None 		     
A0A3Q7HFN5_SOLLC
EnsemblPlants»
0.0
Essential protein Yae1
N-terminal domain-containing protein		 Solanum lycopersicum
TI:4081 None 		     
A0A5F5PKG5_HORSE
Ensembl»
0.0
LTO1 LTO1 maturation factor of ABCE1 Equus caballus
TI:9796 None 		     
A0A5F8H616_MONDO
Ensembl»
0.0
LTO1 LTO1 maturation factor of ABCE1 Monodelphis domestica
TI:13616 None
   
A0A7M7GFK6_STRPU
EnsemblMetazoa»
0.0
Essential protein Yae1
N-terminal domain-containing protein		 Strongylocentrotus purpuratus
TI:7668 None 		     
A0A7U2FBM8_PHANO
TubercuList»
0.0
JI435_052870 Essential protein Yae1
N-terminal domain-containing protein		 Phaeosphaeria nodorum
TI:13684 None 		 
 
A0A804HWG2_MUSAM
EnsemblPlants»
0.0
GSMUA_304410.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None 		 
 
A0A804JKJ3_MUSAM
EnsemblPlants»
0.0
GSMUA_172340.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None 		 
 
A0A804NXW7_MAIZE
EnsemblPlants»
0.0
LOC103635700 Essential protein Yae1
N-terminal domain-containing protein		 Zea mays
TI:4577 None 		     
A0A804NXW8_MAIZE
EnsemblPlants»
0.0
Essential protein Yae1
N-terminal domain-containing protein		 Zea mays
TI:4577 None 		     
A0A804QS21_MAIZE
EnsemblPlants»
0.0
LOC109941502 Essential protein Yae1
N-terminal domain-containing protein		 Zea mays
TI:4577 None 		     
A0A804RHQ2_MAIZE
EnsemblPlants»
0.0
Essential protein Yae1
N-terminal domain-containing protein		 Zea mays
TI:4577 None 		     
A0A8I3RYR3_CANLF
Ensembl»
0.0
LTO1 LTO1 maturation factor of ABCE1 Canis lupus
TI:9612 None
   
A0A8I6YS07_HORVV
EnsemblPlants»
0.0
Essential protein Yae1
N-terminal domain-containing protein		 Hordeum vulgare
TI:4513 None 		     
A0A8V1A7V8_CHICK
Ensembl»
0.0
ORAOV1 Oral cancer overexpressed 1 Gallus gallus
TI:9031 None 		     
A0A8W4FGL3_PIG
Ensembl»
0.0
LTO1 LTO1 maturation factor of ABCE1 Sus scrofa
TI:9823 None 		     
A0A9J7KE65_BRAFL
euHCVdb»
0.0
LOC118403856 Protein LTO1 homolog Branchiostoma floridae
TI:7739 None 		     
A0A9K3EMN9_HELAN
euHCVdb»
0.0
HanXRQr2_Chr13g0619371 Essential protein Yae1 Helianthus annuus
TI:4232 None 		 
 
A0A9K3IAU6_HELAN
euHCVdb»
0.0
HanXRQr2_Chr09g0413401 Essential protein Yae1 Helianthus annuus
TI:4232 None 		 
 
A0A9R1W950_LACSA
euHCVdb»
0.0
LSAT_V11C300155710 Essential protein Yae1
N-terminal domain-containing protein		 Lactuca sativa
TI:4236 None 		 
 
A0AAA9TSV3_BOVIN
Ensembl»
0.0
LTO1 LTO1 maturation factor of ABCE1 Bos taurus
TI:9913 None
   
A0ABI8AE76_FELCA
Ensembl»
0.0
LTO1 Essential protein Yae1
N-terminal domain-containing protein		 Felis catus
TI:9685 None 		     
A0ABM2ZQN1_GOSHI
euHCVdb»
0.0
LOC121214791 Protein LTO1 homolog Gossypium hirsutum
TI:3635 None 		     
A0ABM3AQ17_GOSHI
neXtProt»
0.0
LOC121220951 Protein LTO1 homolog Gossypium hirsutum
TI:3635 None 		     
A1Z8U7_DROME
FlyBase»
0.0
CG33154 GEO13458p1 (MIP04572p1) Drosophila melanogaster
TI:7227 None 		 
 
A2RV85_XENLA
Xenbase»
0.0
lto1.S LOC100037152 protein (oral cancer-overexpressed
protein 1 S homeolog)		 Xenopus laevis
TI:8355 None 		 
 
A4FVI3_DANRE
ZFIN»
0.0
lto1 LTO1 maturation factor of ABCE1
(Oraov1 protein) (Protein LTO1 homolog)		 Danio rerio
TI:7955 None 		 
 
A7EZ59_SCLS1
TubercuList»
0.0
SS1G_10625 Essential protein Yae1
N-terminal domain-containing protein		 Sclerotinia sclerotiorum
TI:5180 None 		 
 
A8IA11_CHLRE
euHCVdb»
0.0
CHLRE_02g075550v5 Essential protein Yae1
N-terminal domain-containing protein		 Chlamydomonas reinhardtii
TI:3055 None 		 
 
A9V940_MONBE
euHCVdb»
0.0
MONBRDRAFT_34013 Essential protein Yae1
N-terminal domain-containing protein		 Monosiga brevicollis
TI:81824 None 		 
 
B3DL39_XENTR
Xenbase»
0.0
lto1 LOC100170452 protein (Lto1) Xenopus tropicalis
TI:8364 None 		 
 
B3RUB9_TRIAD
CTD»
0.0
TRIADDRAFT_55229 Essential protein Yae1
N-terminal domain-containing protein		 Trichoplax adhaerens
TI:10228 None 		 
 
B6K123_SCHJY
TubercuList»
0.0
lto1 DUF1715 family protein Schizosaccharomyces japonicus
TI:4897 None 		 
 
B6TYC1_MAIZE
EnsemblPlants»
0.0
LOC100217108 Oral cancer overexpressed protein
1 (Transferasesfolic acid binding)		 Zea mays
TI:4577 None
 
B7P1I6_IXOSC
EnsemblMetazoa»
0.0
8053528 Oral cancer overexpressed protein, putative Ixodes scapularis
TI:6945 None 		 
 
B8C6W5_THAPS
euHCVdb»
0.0
THAPSDRAFT_7569 Essential protein Yae1
N-terminal domain-containing protein		 Thalassiosira pseudonana
TI:35128 None 		 
 
B9RW61_RICCO
euHCVdb»
0.0
RCOM_1176280 Oral cancer overexpressed protein, putative Ricinus communis
TI:3988 None 		 
 
C0PJF0_MAIZE
EnsemblPlants»
0.0
LOC103646029 Transferasesfolic acid binding Zea mays
TI:4577 None
 
C5Z891_SORBI
euHCVdb»
0.0
SORBI_3010G235200 Essential protein Yae1
N-terminal domain-containing protein		 Sorghum bicolor
TI:4558 None 		 
 
C6TDY5_SOYBN
EnsemblPlants»
0.0
LOC102666559 Essential protein Yae1
N-terminal domain-containing protein		 Glycine max
TI:3847 None 		 
 
D8R3R2_SELML
euHCVdb»
0.0
SELMODRAFT_84379 Essential protein Yae1
N-terminal domain-containing protein		 Selaginella moellendorffii
TI:88036 None 		 
 
D8SIF3_SELML
euHCVdb»
0.0
SELMODRAFT_117435 Essential protein Yae1
N-terminal domain-containing protein		 Selaginella moellendorffii
TI:88036 None 		 
 
E3JQB0_PUCGT
TubercuList»
0.0
PGTG_00335 Essential protein Yae1
N-terminal domain-containing protein		 Puccinia graminis
TI:5297 None 		 
 
E9FS16_DAPPU
neXtProt»
0.0
DAPPUDRAFT_40007 Essential protein Yae1
N-terminal domain-containing protein		 Daphnia pulex
TI:6669 None 		 
 
F0Z6L5_DICPU
TubercuList»
0.0
DICPUDRAFT_146682 Essential protein Yae1
N-terminal domain-containing protein		 Dictyostelium purpureum
TI:5786 None 		 
 
F4NUD1_BATDJ
euHCVdb»
0.0
BATDEDRAFT_85794 Essential protein Yae1
N-terminal domain-containing protein		 Batrachochytrium dendrobatidis
TI:109871 None 		 
 
F6HII0_VITVI
neXtProt»
0.0
VIT_12s0059g02030 Essential protein Yae1
N-terminal domain-containing protein		 Vitis vinifera
TI:29760 None 		 
 
F6YP98_ORNAN
Ensembl»
0.0
LTO1 LTO1 maturation factor of ABCE1 Ornithorhynchus anatinus
TI:9258 None
   
G1KS10_ANOCA
Ensembl»
0.0
LTO1 LTO1 maturation factor of ABCE1 Anolis carolinensis
TI:28377 None
   
G3RNC5_GORGO
Ensembl»
0.0
LTO1 LTO1 maturation factor of ABCE1 Gorilla gorilla
TI:9593 None 		 
 
H3GSH4_PHYRM
EnsemblProtists»
0.0
Essential protein Yae1
N-terminal domain-containing protein		 Phytophthora ramorum
TI:164328 None 		 
 
H9Z2H2_MACMU
Ensembl»
0.0
LTO1 LTO1 maturation factor of ABCE1 (Oral
cancer overexpressed 1) (Oral cancer-overexpressed protein 1)		 Macaca mulatta
TI:9544 None 		 
 
I1GTT9_BRADI
EnsemblPlants»
0.0
LOC100839674 Essential protein Yae1
N-terminal domain-containing protein		 Brachypodium distachyon
TI:15368 None 		 
 
I3T2V3_MEDTR
EnsemblPlants»
0.0
MTR_4g046043 Oral cancer overexpressed protein
(Putative essential protein Yae1)		 Medicago truncatula
TI:3880 None 		 
 
K3YAL9_SETIT
EnsemblPlants»
0.0
LOC101780874 Essential protein Yae1
N-terminal domain-containing protein		 Setaria italica
TI:4555 None 		 
 
K3ZXU9_SETIT
EnsemblPlants»
0.0
LOC111256409 Essential protein Yae1
N-terminal domain-containing protein		 Setaria italica
TI:4555 None 		 
 
K4A098_SETIT
EnsemblPlants»
0.0
Essential protein Yae1
N-terminal domain-containing protein		 Setaria italica
TI:4555 None 		 
 
K7D230_PANTR
Ensembl»
0.0
ORAOV1 LTO1 maturation factor of
ABCE1 (Oral cancer overexpressed 1)		 Pan troglodytes
TI:9598 None 		 
 
K7LG33_SOYBN
EnsemblPlants»
0.0
LOC102668061 Essential protein Yae1
N-terminal domain-containing protein		 Glycine max
TI:3847 None 		 
 
K7UEV0_MAIZE
EnsemblPlants»
0.0
LOC103641192 Oral cancer overexpressed protein 1 Zea mays
TI:4577 None 		 
 
M1C127_SOLTU
EnsemblPlants»
0.0
Oral cancer overexpressed protein Solanum tuberosum
TI:4113 None 		     
M4EQR8_BRACM
EnsemblPlants»
0.0
Uncharacterized protein Brassica campestris
TI:3711 None 		     
Q1K6T0_NEUCR
TubercuList»
0.0
NCU08929 Essential protein Yae1
N-terminal domain-containing protein		 Neurospora crassa
TI:5141 None 		 
 
Q4WTK3_ASPFU
TubercuList»
0.0
AFUA_1G09000 Essential protein Yae1
N-terminal domain-containing protein		 Aspergillus fumigatus
TI:746128 None 		 
 
Q5BDJ9_EMENI
TubercuList»
0.0
ANIA_01381 Essential protein Yae1
N-terminal domain-containing protein		 Emericella nidulans
TI:162425 None 		 
 
Q5KF91_CRYD1
TubercuList»
0.0
CNF02580 Expressed protein Cryptococcus deneoformans
TI:40410 None 		 
 
Q6C4J8_YARLI
TubercuList»
0.0
YALI0_E26169g YALI0E26169p Yarrowia lipolytica
TI:4952 None 		 
 
Q752C1_EREGS
neXtProt»
0.0
AGOS_AFR654W AFR654Wp Eremothecium gossypii
TI:33169 None 		 
 
Q8GVP9_ORYSJ
euHCVdb»
0.0
Os07g0530300 Os07g0530300 protein (cDNA
clone:002-188-H10, full insert sequence)		 Oryza sativa
TI:4530 None 		 
 
Q9LY06_ARATH
TAIR»
0.0
At5g07570 Glycine/proline-rich protein Arabidopsis thaliana
TI:3702 None
 
T1EZQ7_HELRO
EnsemblMetazoa»
0.0
20202057 Uncharacterized protein Helobdella robusta
TI:6412 None 		 
 
W1NN33_AMBTC
euHCVdb»
0.0
AMTR_s00202p00030010 Essential protein Yae1
N-terminal domain-containing protein		 Amborella trichopoda
TI:13333 None 		 
 
W5C7C1_WHEAT
EnsemblPlants»
0.0
LOC123052524 Essential protein Yae1
N-terminal domain-containing protein		 Triticum aestivum
TI:4565 None 		     
W5MCK7_LEPOC
Ensembl»
0.0
LTO1 maturation factor of ABCE1 Lepisosteus oculatus
TI:7918 None