Collated Gene Ontology terms

Biological process: protein-folding chaperone binding(2017)

Molecular function: regulation of low-density lipoprotein particle clearance2020, 2024 negative regulation of gene expression2020, 2024 positive regulation of low-density lipoprotein receptor activity2020, 2024 regulation of protein secretion2011 regulation of protein processing2011 regulation of fibroblast growth factor receptor signaling pathway2013 polarity specification of dorsal/ventral axis2011 midbrain-hindbrain boundary development2006 maternal specification of dorsal/ventral axis, oocyte, germ-line encoded2006 fibroblast growth factor receptor signaling pathway2006
determination of left/right symmetry2013 chaperone-mediated protein folding2017 Kupffer's vesicle development2013

Cellular component: endoplasmic reticulum2006, 2011, 2017, 2024 membrane2024 endomembrane system2014

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 34/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
U5D6X9_AMBTC
EnsemblPlants»
0.0
AMTR_s00044p00140280 DUF3456 domain-containing protein Amborella trichopoda
TI:13333 None 		 
 
A0A803T698_ANOCA
Ensembl»
0.0
cnpy1 Canopy FGF signaling regulator 1 Anolis carolinensis
TI:28377 None 		     
A0A803TU50_ANOCA
Ensembl»
0.0
Saposin B-type domain-containing protein Anolis carolinensis
TI:28377 None 		     
Q7PPM0_ANOGA
EnsemblMetazoa»
0.0
1275464 AGAP008615-PA Anopheles gambiae
TI:7165 None
 
F4I9G7_ARATH
TAIR»
0.0
At1g42480 TLR4 regulator/MIR-interacting MSAP protein Arabidopsis thaliana
TI:3702 None 		 
 
Q1LZ72_BOVIN
Ensembl»
0.0
CNPY2 Canopy 2 homolog (Zebrafish)
(Canopy FGF signaling regulator 2)		 Bos taurus
TI:9913 None
 
A0A2K2CUM7_BRADI
EnsemblPlants»
0.0
BRADI_3g01590v3 DUF3456 domain-containing protein Brachypodium distachyon
TI:15368 None 		 
 
C3YL01_BRAFL
CTD»
0.0
LOC118403231 Protein canopy homolog 2-like Branchiostoma floridae
TI:7739 None
 
A0A078HEC0_BRANA
EnsemblPlants»
0.0
BnaA08g04550D BnaA08g04550D protein Brassica napus
TI:3708 None 		 
 
M4F1J2_BRACM
EnsemblPlants»
0.0
DUF3456 domain-containing protein Brassica campestris
TI:3711 None 		     
A8X7W0_CAEBR
WormBase»
0.0
CBG09065 CBG_09065 Protein CBG09065 Caenorhabditis briggsae
TI:6238 None
 
A8X7W1_CAEBR
WormBase»
0.0
CBG09064 CBG_09064 Protein CBG09064 Caenorhabditis briggsae
TI:6238 None
 
A8XMW9_CAEBR
WormBase»
0.0
CBG15841 CBG_15841 Protein CBG15841 Caenorhabditis briggsae
TI:6238 None
 
Q19090_CAEEL
WormBase»
0.0
CELE_F01F1.11 F01F1.11 PAP-associated domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q95QN1_CAEEL
WormBase»
0.0
CELE_F01F1.15 F01F1.15 DUF3456 domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q9U2B1_CAEEL
WormBase»
0.0
CELE_Y47H9C.8 Y47H9C.8 NACHT_N domain-containing protein Caenorhabditis elegans
TI:6239 None
 
A0A8I3NPH3_CANLF
Ensembl»
0.0
CNPY1 Uncharacterized protein Canis lupus
TI:9612 None 		     
A0A8I3RVQ5_CANLF
Ensembl»
0.0
CNPY2 Canopy FGF signaling regulator 2 Canis lupus
TI:9612 None
   
A0A1U8GA99_CAPAN
EnsemblPlants»
0.0
T459_13500 DUF3456 domain-containing protein Capsicum annuum
TI:4072 None 		 
 
A0A2K3CTL2_CHLRE
EnsemblPlants»
0.0
CHLRE_16g661700v5 DUF3456 domain-containing protein Chlamydomonas reinhardtii
TI:3055 None 		 
 
F6WYY0_CIOIN
Ensembl»
0.0
DUF3456 domain-containing protein Ciona intestinalis
TI:7719 None 		 
 
A0A067H2M0_CITSI
Ensembl»
0.0
CISIN_1g030030mg DUF3456 domain-containing protein Citrus sinensis
TI:2711 None 		 
 
A0A0A0L1D8_CUCSA
EnsemblPlants»
0.0
Csa_4G664260 DUF3456 domain-containing protein Cucumis sativus
TI:3659 None 		 
 
CNPY1_DANRE
ZFIN»
4.0
cnpy1 Protein canopy-1 (Protein D121) Danio rerio
TI:7955 None
 
Q0V965_DANRE
ZFIN»
0.0
tmem4 Canopy 2 (Cnpy2 protein)
(Protein canopy homolog 2 precursor)		 Danio rerio
TI:7955 None
 
E9H737_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_308242 DUF3456 domain-containing protein Daphnia pulex
TI:6669 None
 
SEELE_DROME
FlyBase»
3.9
sel Protein seele Drosophila melanogaster
TI:7227 None
 
F6YKG5_HORSE
Ensembl»
0.0
Saposin B-type domain-containing protein Equus caballus
TI:9796 None
   
F7DEN7_HORSE
Ensembl»
0.0
CNPY2 Canopy FGF signaling regulator 2 Equus caballus
TI:9796 None
   
A0A022RN17_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a014440mg DUF3456 domain-containing protein Erythranthe guttata
TI:4155 None 		 
 
A0A337SBZ2_FELCA
Ensembl»
0.0
CNPY1 DUF3456 domain-containing protein Felis catus
TI:9685 None
 
M3WG69_FELCA
Ensembl»
0.0
CNPY2 Canopy FGF signaling regulator 2 Felis catus
TI:9685 None
 
A0A8V1A106_CHICK
Ensembl»
0.0
CNPY2 DUF3456 domain-containing protein Gallus gallus
TI:9031 None 		     
I1K7B2_SOYBN
EnsemblPlants»
0.0
100781382 DUF3456 domain-containing protein Glycine max
TI:3847 None 		 
 
A0A2I2Y7M1_GORGO
Ensembl»
0.0
DUF3456 domain-containing protein Gorilla gorilla
TI:9593 None
 
A0A2I2YPF1_GORGO
Ensembl»
0.0
Canopy FGF signaling regulator 1 Gorilla gorilla
TI:9593 None
 
G3R152_GORGO
Ensembl»
0.0
CNPY2 Canopy FGF signaling regulator 2 Gorilla gorilla
TI:9593 None
 
A0A1U8L2W4_GOSHI
Ensembl»
0.0
LOC107922048 Protein canopy-1 Gossypium hirsutum
TI:3635 None 		     
A0A1U8N6C2_GOSHI
Ensembl»
0.0
LOC107945238 Uncharacterized protein LOC107945238 Gossypium hirsutum
TI:3635 None 		     
A0A251U4M6_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr08g0216381 HanXRQr2_Chr08g0327341 DUF3456 domain-containing protein Helianthus annuus
TI:4232 None 		 
 
T1EX95_HELRO
EnsemblMetazoa»
0.0
20201195 DUF3456 domain-containing protein Helobdella robusta
TI:6412 None
 
CNPY1_HUMAN
Ensembl»
0.0
CNPY1 Protein canopy homolog 1 Homo sapiens
TI:9606 None 		 
 
CNPY2_HUMAN
Ensembl»
1.5
CNPY2 Protein canopy homolog 2 (MIR-interacting saposin-like protein)
(Putative secreted protein Zsig9) (Transmembrane protein 4)		 Homo sapiens
TI:9606 None
 
F8VP03_HUMAN
Ensembl»
0.0
DUF3456 domain-containing protein Homo sapiens
TI:9606 None 		 
 
A0A8I6YGE1_HORVV
EnsemblPlants»
0.0
DUF3456 domain-containing protein Hordeum vulgare
TI:4513 None 		     
B7Q7J5_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW010982 ER protein with KEEL retention signal, putative
(ER protein with KEEL retention signal, putative (Fragment))		 Ixodes scapularis
TI:6945 None
 
A0A2I4HWR0_JUGRE
EnsemblPlants»
0.0
LOC109022227 Protein canopy-1 Juglans regia
TI:51240 None 		     
A0A1Y1IFA3_KLENI
EnsemblPlants»
0.0
KFL_005370070 DUF3456 domain-containing protein Klebsormidium nitens
TI:105231 None 		 
 
W5MB38_LEPOC
Ensembl»
0.0
Canopy FGF signaling regulator 2 Lepisosteus oculatus
TI:7918 None
 
W5N426_LEPOC
Ensembl»
0.0
Canopy FGF signaling regulator 1 Lepisosteus oculatus
TI:7918 None
 
A0A5F8A2S8_MACMU
Ensembl»
0.0
CNPY1 Canopy FGF signaling regulator 1 Macaca mulatta
TI:9544 None
   
A0A2C9TZG5_MANES
EnsemblPlants»
0.0
MANES_18G003600 DUF3456 domain-containing protein Manihot esculenta
TI:3983 None 		 
 
A0A2C9UPL0_MANES
EnsemblPlants»
0.0
MANES_13G069000 DUF3456 domain-containing protein Manihot esculenta
TI:3983 None
 
G7J5Y0_MEDTR
EnsemblPlants»
0.0
11422510 Canopy-like protein Medicago truncatula
TI:3880 None 		 
 
F7FKR0_MONDO
Ensembl»
0.0
Canopy FGF signaling regulator 1 Monodelphis domestica
TI:13616 None
   
CNPY1_MOUSE
Ensembl»
0.0
Cnpy1 Protein canopy homolog 1 Mus musculus
TI:10090 None 		 
 
CNPY2_MOUSE
Ensembl»
2.4
Cnpy2 Protein canopy homolog 2 (MIR-interacting saposin-like protein)
(Putative secreted protein ZSIG9) (Transmembrane protein 4)		 Mus musculus
TI:10090 None
 
A0A804HST4_MUSAM
EnsemblPlants»
0.0
103982696 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None 		 
 
A0A1U8AT06_NELNU
EnsemblBacteria»
0.0
LOC104603788 Protein canopy-1 Nelumbo nucifera
TI:4432 None
   
A7RY51_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g97340 DUF3456 domain-containing protein Nematostella vectensis
TI:45351 None
 
A8DVK5_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g156534 DUF3456 domain-containing protein Nematostella vectensis
TI:45351 None
 
A0A1S4ATV5_TOBAC
EnsemblFungi»
0.0
LOC107801163 Protein canopy homolog 1-like isoform X1 Nicotiana tabacum
TI:4097 None 		     
A0A1S4CMW1_TOBAC
EnsemblFungi»
0.0
LOC107820745 Protein canopy homolog 1-like isoform X3 Nicotiana tabacum
TI:4097 None 		     
A0A6I8PEQ4_ORNAN
Ensembl»
0.0
CNPY2 Canopy FGF signaling regulator 2 Ornithorhynchus anatinus
TI:9258 None
   
A0A6I8PLH5_ORNAN
Ensembl»
0.0
CNPY1 Canopy FGF signaling regulator 1 Ornithorhynchus anatinus
TI:9258 None
   
Q0E4I9_ORYSJ
EnsemblPlants»
0.0
Os02g0117200 Os02g0117200 protein Oryza sativa
TI:4530 None 		 
 
A0A3B3HJT9_ORYLA
Ensembl»
0.0
LOC101175475 Protein canopy homolog 2 Oryzias latipes
TI:8090 None
   
H2LVG0_ORYLA
Ensembl»
0.0
LOC101161751 Protein canopy-1 Oryzias latipes
TI:8090 None
   
A0A2I3TCJ0_PANTR
Ensembl»
0.0
CNPY1 Canopy FGF signaling regulator 1 Pan troglodytes
TI:9598 None 		 
 
H2Q686_PANTR
Ensembl»
0.0
CNPY2 Canopy 2 homolog (Zebrafish)
(Canopy FGF signaling regulator 2)		 Pan troglodytes
TI:9598 None
 
A0A2K1KVF1_PHYPA
EnsemblPlants»
0.0
PHYPA_004758 DUF3456 domain-containing protein Physcomitrium patens
TI:3218 None 		 
 
A0A3N7FX71_POPTR
EnsemblPlants»
0.0
POPTR_005G253600 DUF3456 domain-containing protein Populus trichocarpa
TI:3694 None 		 
 
M5WAS4_PRUPE
EnsemblPlants»
0.0
PRUPE_5G008700 Uncharacterized protein Prunus persica
TI:3760 None 		 
 
A0A8I6ADY0_RAT
RGD»
0.0
Cnpy1 Canopy FGF signaling regulator 1 Rattus norvegicus
TI:10116 None 		     
A0JN30_RAT
RGD»
1.0
Cnpy2 Canopy FGF signaling regulator 2 Rattus norvegicus
TI:10116 None
   
B9R8Q8_RICCO
EnsemblBacteria»
0.0
RCOM_1601670 DUF3456 domain-containing protein Ricinus communis
TI:3988 None 		 
 
K3YVZ3_SETIT
EnsemblPlants»
0.0
101757094 DUF3456 domain-containing protein Setaria italica
TI:4555 None 		 
 
A0A3Q7GCI8_SOLLC
EnsemblPlants»
0.0
101263112 DUF3456 domain-containing protein Solanum lycopersicum
TI:4081 None
   
M1ALU0_SOLTU
EnsemblPlants»
0.0
102602787 DUF3456 domain-containing protein Solanum tuberosum
TI:4113 None
   
A0A194YM47_SORBI
EnsemblPlants»
0.0
SORBI_3004G013000 DUF3456 domain-containing protein Sorghum bicolor
TI:4558 None 		 
 
A0A7M7LTJ7_STRPU
EnsemblMetazoa»
0.0
Saposin B-type domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7MYN5_STRPU
EnsemblMetazoa»
0.0
Saposin B-type domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A4X1W9B8_PIG
Ensembl»
0.0
CNPY2 Canopy FGF signaling regulator 2 Sus scrofa
TI:9823 None
   
A0A5G2RDT5_PIG
Ensembl»
0.0
CNPY1 Uncharacterized protein Sus scrofa
TI:9823 None 		     
A0A061FEI4_THECC
EnsemblPlants»
0.0
TCM_034419 Canopy isoform 1 Theobroma cacao
TI:3641 None 		 
 
D6WRV5_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_09499 Protein canopy homolog 1-like Protein Tribolium castaneum
TI:7070 None
 
A0A3B6NJQ3_WHEAT
EnsemblPlants»
0.0
CFC21_081843 DUF3456 domain-containing protein Triticum aestivum
TI:4565 None 		 
 
A0A3B6PHK8_WHEAT
EnsemblPlants»
0.0
DUF3456 domain-containing protein Triticum aestivum
TI:4565 None 		     
A0A3B6QCJ4_WHEAT
EnsemblPlants»
0.0
CFC21_091234 DUF3456 domain-containing protein Triticum aestivum
TI:4565 None 		 
 
D7UDC4_VITVI
EnsemblPlants»
0.0
VIT_18s0122g01020 DUF3456 domain-containing protein Vitis vinifera
TI:29760 None 		 
 
A0A1L8FV61_XENLA
Xenbase»
0.0
cnpy1.L protein canopy homolog 1-like Xenopus laevis
TI:8355 None
   
A0A8J1M5U4_XENLA
CTD»
0.0
cnpy2.L Uncharacterized protein LOC734679 isoform X1 Xenopus laevis
TI:8355 None
   
CNPY1_XENLA
Xenbase»
0.0
cnpy1 Protein canopy homolog 1 Xenopus laevis
TI:8355 None
 
F6WI24_XENTR
Xenbase»
0.0
cnpy1 Canopy FGF-signaling regulator 1
(Protein canopy homolog 1)		 Xenopus tropicalis
TI:8364 None 		     
Q28FU2_XENTR
Xenbase»
0.0
cnpy2 Canopy FGF signaling regulator 2 (Protein canopy homolog 2
isoform X1) (Protein canopy homolog 2 precursor) (Transmembrane protein 4)		 Xenopus tropicalis
TI:8364 None 		 
 
Q6GPD6_XENLA
Xenbase»
0.0
cnpy2.S Canopy FGF signaling regulator 2
S homeolog precursor (MGC80474 protein)		 Xenopus laevis
TI:8355 None
 
A0A0K9PI53_ZOSMR
EnsemblPlants»
0.0
ZOSMA_251G00030 DUF3456 domain-containing protein Zostera marina
TI:29655 None