Collated Gene Ontology terms

Biological process: protein folding chaperone(2025)

Molecular function: regulation of low-density lipoprotein particle clearance2020 negative regulation of gene expression2020 regulation of protein secretion2011 regulation of protein processing2011 regulation of fibroblast growth factor receptor signaling pathway2013 protein folding2025 polarity specification of dorsal/ventral axis2011 midbrain-hindbrain boundary development2006 maternal specification of dorsal/ventral axis, oocyte, germ-line encoded2006 fibroblast growth factor receptor signaling pathway2006
determination of left/right symmetry2013 Kupffer's vesicle development2013

Cellular component: endoplasmic reticulum2006, 2011, 2017, 2025 endomembrane system2014

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 35/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
SEELE_DROME
FlyBase»
3.9
sel Protein seele Drosophila melanogaster
TI:7227 None
 
Q6GPD6_XENLA
Xenbase»
0.0
cnpy2.S Canopy FGF signaling regulator 2
S homeolog precursor (MGC80474 protein)		 Xenopus laevis
TI:8355 None
 
Q4KLC8_XENLA
Xenbase»
0.0
cnpy2.L MGC116481 protein (Uncharacterized
protein LOC734679 precursor)		 Xenopus laevis
TI:8355 None
 
A0A803TU50_ANOCA
Ensembl»
0.0
cnpy2 Saposin B-type domain-containing protein Anolis carolinensis
TI:28377 None
   
H2ML65_ORYLA
Ensembl»
0.0
cnpy2 Canopy FGF signaling regulator 2 Oryzias latipes
TI:8090 None 		     
Q0V965_DANRE
ZFIN»
0.0
cnpy2 Canopy 2 (Cnpy2 protein)
(Protein canopy homolog 2 precursor)		 Danio rerio
TI:7955 None
 
Q28FU2_XENTR
Xenbase»
0.0
cnpy2 Canopy FGF signaling regulator 2 (Protein canopy homolog 2
isoform X1) (Protein canopy homolog 2 precursor) (Transmembrane protein 4)		 Xenopus tropicalis
TI:8364 None
 
A0A1L8FV61_XENLA
Xenbase»
0.0
cnpy1.L protein canopy homolog 1-like Xenopus laevis
TI:8355 None
   
A0A803SY27_ANOCA
Ensembl»
0.0
cnpy1 Saposin B-type domain-containing protein Anolis carolinensis
TI:28377 None 		     
CNPY1_DANRE
ZFIN»
4.0
cnpy1 Protein canopy-1 (Protein D121) Danio rerio
TI:7955 None
 
CNPY1_XENLA
Xenbase»
0.0
cnpy1 Protein canopy homolog 1 Xenopus laevis
TI:8355 None
 
F6WI24_XENTR
Xenbase»
0.0
cnpy1 Canopy FGF-signaling regulator 1
(Protein canopy homolog 1)		 Xenopus tropicalis
TI:8364 None
   
A0A0K9PI53_ZOSMR
euHCVdb»
0.0
ZOSMA_251G00030 DUF3456 domain-containing protein Zostera marina
TI:29655 None 		 
 
D7UDC4_VITVI
euHCVdb»
0.0
VIT_18s0122g01020 DUF3456 domain-containing protein Vitis vinifera
TI:29760 None 		 
 
A0A061FEI4_THECC
euHCVdb»
0.0
TCM_034419 Canopy isoform 1 Theobroma cacao
TI:3641 None 		 
 
A0A1U8GA99_CAPAN
euHCVdb»
0.0
T459_13500 DUF3456 domain-containing protein Capsicum annuum
TI:4072 None 		 
 
A0A194YM47_SORBI
euHCVdb»
0.0
SORBI_3004G013000 DUF3456 domain-containing protein Sorghum bicolor
TI:4558 None 		 
 
A0ABI7ZYV1_FELCA
Ensembl»
0.0
S100A3 Saposin B-type domain-containing protein Felis catus
TI:9685 None 		     
B9R8Q8_RICCO
neXtProt»
0.0
RCOM_1601670 DUF3456 domain-containing protein Ricinus communis
TI:3988 None 		 
 
M5WAS4_PRUPE
euHCVdb»
0.0
PRUPE_5G008700 Uncharacterized protein Prunus persica
TI:3760 None 		 
 
A0A3N7FX71_POPTR
neXtProt»
0.0
POPTR_005G253600 DUF3456 domain-containing protein Populus trichocarpa
TI:3694 None 		 
 
Q0E4I9_ORYSJ
neXtProt»
0.0
Os02g0117200 Os02g0117200 protein Oryza sativa
TI:4530 None 		 
 
A7RY51_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g97340 DUF3456 domain-containing protein Nematostella vectensis
TI:45351 None
 
A8DVK5_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g156534 DUF3456 domain-containing protein Nematostella vectensis
TI:45351 None
 
A0A022RN17_ERYGU
neXtProt»
0.0
MIMGU_mgv1a014440mg DUF3456 domain-containing protein Erythranthe guttata
TI:4155 None 		 
 
A0A2C9TZG5_MANES
neXtProt»
0.0
MANES_18G003600v8 DUF3456 domain-containing protein Manihot esculenta
TI:3983 None 		 
 
A0A9R1UNY2_LACSA
euHCVdb»
0.0
LSAT_V11C800400120 DUF3456 domain-containing protein Lactuca sativa
TI:4236 None 		 
 
A0A8I6YGE1_HORVV
EnsemblPlants»
0.0
LOC123403551 DUF3456 domain-containing protein Hordeum vulgare
TI:4513 None 		     
A0A3B6QCJ4_WHEAT
EnsemblPlants»
0.0
LOC123143230 DUF3456 domain-containing protein Triticum aestivum
TI:4565 None 		     
A0A3B6NJQ3_WHEAT
EnsemblPlants»
0.0
LOC123131776 DUF3456 domain-containing protein Triticum aestivum
TI:4565 None 		     
C3YL01_BRAFL
euHCVdb»
0.0
LOC118403231 Protein canopy homolog 2-like Branchiostoma floridae
TI:7739 None
 
A0A2K1KVF1_PHYPA
EnsemblPlants»
0.0
LOC112280014 DUF3456 domain-containing protein Physcomitrium patens
TI:3218 None 		 
 
A0A9R0J845_SPIOL
euHCVdb»
0.0
LOC110802074 DUF3456 domain-containing protein Spinacia oleracea
TI:3562 None 		     
A0A2I4HWR0_JUGRE
euHCVdb»
0.0
LOC109022227 Protein canopy-1 Juglans regia
TI:51240 None 		     
A0ABM3BX06_GOSHI
euHCVdb»
0.0
LOC107945238 Protein seele Gossypium hirsutum
TI:3635 None 		     
A0A1U8L2W4_GOSHI
euHCVdb»
0.0
LOC107922048 Protein canopy-1 Gossypium hirsutum
TI:3635 None 		     
A0A1S4CMS1_TOBAC
euHCVdb»
0.0
LOC107820745 Uncharacterized protein LOC107820745 isoform X1 Nicotiana tabacum
TI:4097 None 		     
A0A1U8AT06_NELNU
euHCVdb»
0.0
LOC104603788 Protein canopy-1 Nelumbo nucifera
TI:4432 None 		     
M1ALU0_SOLTU
EnsemblPlants»
0.0
LOC102602787 DUF3456 domain-containing protein Solanum tuberosum
TI:4113 None 		     
K3YVZ3_SETIT
EnsemblPlants»
0.0
LOC101757094 DUF3456 domain-containing protein Setaria italica
TI:4555 None 		 
 
A0A3Q7GCI8_SOLLC
EnsemblPlants»
0.0
LOC101263112 DUF3456 domain-containing protein Solanum lycopersicum
TI:4081 None 		     
A0A2K2CUM7_BRADI
EnsemblPlants»
0.0
LOC100822251 DUF3456 domain-containing protein Brachypodium distachyon
TI:15368 None 		 
 
I1K7B2_SOYBN
EnsemblPlants»
0.0
LOC100781382 DUF3456 domain-containing protein Glycine max
TI:3847 None 		 
 
A0A1Y1IFA3_KLENI
euHCVdb»
0.0
KFL_005370070 DUF3456 domain-containing protein Klebsormidium nitens
TI:105231 None 		 
 
B7Q7J5_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW010982 ER protein with KEEL retention signal, putative Ixodes scapularis
TI:6945 None
 
A0A251U4M6_HELAN
neXtProt»
0.0
HannXRQ_Chr08g0216381 HanXRQr2_Chr08g0327341 DUF3456 domain-containing protein Helianthus annuus
TI:4232 None 		 
 
A0A804HST4_MUSAM
EnsemblPlants»
0.0
GSMUA_295020.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None 		 
 
E9H737_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_308242 DUF3456 domain-containing protein Daphnia pulex
TI:6669 None
 
A0A0A0L1D8_CUCSA
euHCVdb»
0.0
Csa_4G664260 DUF3456 domain-containing protein Cucumis sativus
TI:3659 None 		 
 
A0JN30_RAT
RGD»
0.0
Cnpy2 Canopy FGF signaling regulator 2 Rattus norvegicus
TI:10116 None
   
CNPY2_MOUSE
Ensembl»
1.6
Cnpy2 Protein canopy homolog 2 (MIR-interacting saposin-like protein)
(Putative secreted protein ZSIG9) (Transmembrane protein 4)		 Mus musculus
TI:10090 None
 
A0A8I6ADY0_RAT
RGD»
0.0
Cnpy1 Canopy FGF signaling regulator 1 Rattus norvegicus
TI:10116 None
   
CNPY1_MOUSE
Ensembl»
0.0
Cnpy1 Protein canopy homolog 1 Mus musculus
TI:10090 None 		 
 
A0A4X1W9B8_PIG
Ensembl»
0.0
CNPY2 Canopy FGF signaling regulator 2 Sus scrofa
TI:9823 None
   
A0A6I8PEQ4_ORNAN
Ensembl»
0.0
CNPY2 Canopy FGF signaling regulator 2 Ornithorhynchus anatinus
TI:9258 None
   
A0A8I3RVQ5_CANLF
Ensembl»
0.0
CNPY2 Canopy FGF signaling regulator 2 Canis lupus
TI:9612 None
   
A0A8V1A106_CHICK
Ensembl»
0.0
CNPY2 Canopy FGF signaling regulator 2 Gallus gallus
TI:9031 None
   
CNPY2_HUMAN
Ensembl»
1.0
CNPY2 Protein canopy homolog 2 (MIR-interacting saposin-like protein)
(Putative secreted protein Zsig9) (Transmembrane protein 4)		 Homo sapiens
TI:9606 None
 
G3R152_GORGO
Ensembl»
0.0
CNPY2 Canopy FGF signaling regulator 2 Gorilla gorilla
TI:9593 None
 
K7BRY4_PANTR
Ensembl»
0.0
CNPY2 Canopy 2 homolog (Zebrafish)
(Canopy FGF signaling regulator 2)		 Pan troglodytes
TI:9598 None 		 
 
Q1LZ72_BOVIN
Ensembl»
0.0
CNPY2 Canopy 2 homolog (Zebrafish)
(Canopy FGF signaling regulator 2)		 Bos taurus
TI:9913 None
 
A0A2I2YPF1_GORGO
Ensembl»
0.0
CNPY1 Canopy FGF signaling regulator 1 Gorilla gorilla
TI:9593 None
 
A0A2I3TCJ0_PANTR
Ensembl»
0.0
CNPY1 Canopy FGF signaling regulator 1 Pan troglodytes
TI:9598 None 		 
 
A0A3B3H6M7_ORYLA
Ensembl»
0.0
CNPY1 Canopy FGF signaling regulator 1 Oryzias latipes
TI:8090 None 		     
A0A5F8A2S8_MACMU
Ensembl»
0.0
CNPY1 Canopy FGF signaling regulator 1 Macaca mulatta
TI:9544 None
   
A0A5G2RDT5_PIG
Ensembl»
0.0
CNPY1 Canopy FGF signaling regulator 1 Sus scrofa
TI:9823 None 		     
A0A6I8PLH5_ORNAN
Ensembl»
0.0
CNPY1 Canopy FGF signaling regulator 1 Ornithorhynchus anatinus
TI:9258 None
   
A0A8I3NPH3_CANLF
Ensembl»
0.0
CNPY1 Canopy FGF signaling regulator 1 Canis lupus
TI:9612 None
   
CNPY1_HUMAN
Ensembl»
0.0
CNPY1 Protein canopy homolog 1 Homo sapiens
TI:9606 None 		 
 
F7FKR0_MONDO
Ensembl»
0.0
CNPY1 Canopy FGF signaling regulator 1 Monodelphis domestica
TI:13616 None
   
A0A067H2M0_CITSI
euHCVdb»
0.0
CISIN_1g030030mg DUF3456 domain-containing protein Citrus sinensis
TI:2711 None 		 
 
A0A2K3CTL2_CHLRE
euHCVdb»
0.0
CHLRE_16g661700v5 DUF3456 domain-containing protein Chlamydomonas reinhardtii
TI:3055 None 		 
 
Q9U2B1_CAEEL
WormBase»
0.0
CELE_Y47H9C.8 Y47H9C.8 NACHT_N domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q95QN1_CAEEL
WormBase»
0.0
CELE_F01F1.15 F01F1.15 DUF3456 domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q19090_CAEEL
WormBase»
0.0
CELE_F01F1.11 F01F1.11 PAP-associated domain-containing protein Caenorhabditis elegans
TI:6239 None
 
A8XMW9_CAEBR
WormBase»
0.0
CBG15841 CBG_15841 Protein CBG15841 Caenorhabditis briggsae
TI:6238 None
 
A8X7W0_CAEBR
WormBase»
0.0
CBG09065 CBG_09065 Protein CBG09065 Caenorhabditis briggsae
TI:6238 None
 
A8X7W1_CAEBR
WormBase»
0.0
CBG09064 CBG_09064 Protein CBG09064 Caenorhabditis briggsae
TI:6238 None
 
A0A078HEC0_BRANA
euHCVdb»
0.0
BnaA08g04550D BnaA08g04550D protein Brassica napus
TI:3708 None 		 
 
D6WRV5_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_09499 Protein canopy homolog 1-like Protein Tribolium castaneum
TI:7070 None
 
U5D6X9_AMBTC
euHCVdb»
0.0
AMTR_s00044p00140280 DUF3456 domain-containing protein Amborella trichopoda
TI:13333 None 		 
 
T1EX95_HELRO
EnsemblMetazoa»
0.0
20201195 DUF3456 domain-containing protein Helobdella robusta
TI:6412 None
 
Q7PPM0_ANOGA
EnsemblMetazoa»
0.0
1275464 AGAP008615-PA Anopheles gambiae
TI:7165 None
 
G7J5Y0_MEDTR
EnsemblPlants»
0.0
11422510 Canopy-like protein Medicago truncatula
TI:3880 None 		 
 
A0A2I2Y7M1_GORGO
Ensembl»
0.0
DUF3456 domain-containing protein Gorilla gorilla
TI:9593 None
 
A0A3B6PHK8_WHEAT
EnsemblPlants»
0.0
DUF3456 domain-containing protein Triticum aestivum
TI:4565 None 		     
A0A7M7LTJ7_STRPU
EnsemblMetazoa»
0.0
Saposin B-type domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7MYN5_STRPU
EnsemblMetazoa»
0.0
Saposin B-type domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0AAA9SHH5_BOVIN
Ensembl»
0.0
Canopy FGF signaling regulator 1 Bos taurus
TI:9913 None 		     
A0ABI7VRE0_FELCA
Ensembl»
0.0
DUF3456 domain-containing protein Felis catus
TI:9685 None 		     
F6WYY0_CIOIN
Ensembl»
0.0
DUF3456 domain-containing protein Ciona intestinalis
TI:7719 None 		 
 
F6YKG5_HORSE
Ensembl»
0.0
DUF3456 domain-containing protein Equus caballus
TI:9796 None
   
F7DEN7_HORSE
Ensembl»
0.0
Canopy FGF signaling regulator 2 Equus caballus
TI:9796 None
   
F8VP03_HUMAN
Ensembl»
0.0
DUF3456 domain-containing protein Homo sapiens
TI:9606 None 		 
 
M4F1J2_BRACM
EnsemblPlants»
0.0
DUF3456 domain-containing protein Brassica campestris
TI:3711 None 		     
W5MB38_LEPOC
Ensembl»
0.0
Canopy FGF signaling regulator 2 Lepisosteus oculatus
TI:7918 None
 
W5N426_LEPOC
Ensembl»
0.0
Canopy FGF signaling regulator 1 Lepisosteus oculatus
TI:7918 None