Collated Gene Ontology terms

Biological process: protein serine/threonine kinase activity(2015, 2025) ATP binding(2025) protein kinase activity(2025) nucleotide binding(2025) transferase activity(2025) kinase activity(2025) protein serine kinase activity(2025) MAP kinase kinase kinase activity(2022) small GTPase binding(2025)

Molecular function: MAPK cascade2025 cell division2025 spermatogenesis2025 spermatid development2023 ribophagy2023 regulation of cell division2015 protein autophosphorylation2015 flagellated sperm motility2023 cell differentiation2025 autophagy2025
regulation of unidimensional cell growth2015 regulation of extent of cell growth2015 regulation of embryonic development2015 intracellular protein transport2025 animal organ development2025

Cellular component: cytosol2006, 2019, 2025 microtubule organizing center2025 plasma membrane2006, 2018, 2025 nucleolus2015, 2025 cytoplasm2022 vacuole2021 extracellular exosome2013

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 2/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 2/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 1/3 
Excavates: 1/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 35/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
M3KE1_ARATH
TAIR»
5.2
M3KE1 MAP3K epsilon protein kinase 1 (AtM3KE1) (EC
2.7.11.1) (Mitogen-activated protein kinase kinase kinase 7)		 Arabidopsis thaliana
TI:3702 None
 
M3KE2_ARATH
TAIR»
2.5
MAP3KE2 MAP3K epsilon protein kinase 2 (EC
2.7.11.1) (Mitogen-activated protein kinase kinase kinase 6)		 Arabidopsis thaliana
TI:3702 None
 
B9S4I8_RICCO
neXtProt»
0.0
RCOM_0807920 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Ricinus communis
TI:3988 None
 
A0A061E3H5_THECC
euHCVdb»
0.0
TCM_007745 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Theobroma cacao
TI:3641 None
 
A0A067ECQ8_CITSI
neXtProt»
0.0
CISIN_1g000533mg non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Citrus sinensis
TI:2711 None
 
A0A072UXH7_MEDTR
EnsemblPlants»
0.0
25492839 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Medicago truncatula
TI:3880 None
 
A0A078F3J0_BRANA
euHCVdb»
0.0
BnaC03g35620D non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Brassica napus
TI:3708 None
 
A0A078GHS2_BRANA
neXtProt»
0.0
BnaC01g37580D non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Brassica napus
TI:3708 None
 
A0A0K9PZK1_ZOSMR
neXtProt»
0.0
ZOSMA_12G00430 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Zostera marina
TI:29655 None
 
A0A1S3XZ05_TOBAC
euHCVdb»
0.0
LOC107770294 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Nicotiana tabacum
TI:4097 None
   
A0A1S3YS76_TOBAC
euHCVdb»
0.0
LOC107779210 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Nicotiana tabacum
TI:4097 None
   
A0A1U7Z6X0_NELNU
euHCVdb»
0.0
LOC104589884 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Nelumbo nucifera
TI:4432 None
   
A0A1U8J3W2_GOSHI
euHCVdb»
0.0
LOC107901735 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Gossypium hirsutum
TI:3635 None
   
A0A1U8NA08_GOSHI
euHCVdb»
0.0
LOC107946113 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Gossypium hirsutum
TI:3635 None
   
A0A251JUH5_MANES
neXtProt»
0.0
MANES_11G101900 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Manihot esculenta
TI:3983 None
 
A0A251RMV2_HELAN
euHCVdb»
0.0
HannXRQ_Chr17g0540841 HanXRQr2_Chr17g0789041 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Helianthus annuus
TI:4232 None
 
A0A251UHF8_HELAN
euHCVdb»
0.0
MAPKKK7 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Helianthus annuus
TI:4232 None
 
A0A2G2ZGK9_CAPAN
euHCVdb»
0.0
T459_14056 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Capsicum annuum
TI:4072 None
 
A0A2I4FID1_JUGRE
euHCVdb»
0.0
LOC108999066 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Juglans regia
TI:51240 None
   
A0A3N7FC26_POPTR
neXtProt»
0.0
POPTR_007G070100 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Populus trichocarpa
TI:3694 None
 
A0A3N7FV41_POPTR
neXtProt»
0.0
POPTR_005G094200 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Populus trichocarpa
TI:3694 None
 
A0A3Q7IW06_SOLLC
EnsemblPlants»
0.0
MAPKKKe non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Solanum lycopersicum
TI:4081 None
   
A0A804L8X0_MUSAM
EnsemblPlants»
0.0
non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Musa acuminata
TI:4641 None
   
A0A9R1W7F7_LACSA
euHCVdb»
0.0
LSAT_V11C300115000 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Lactuca sativa
TI:4236 None
 
F6HF39_VITVI
euHCVdb»
0.0
VIT_01s0011g02270 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Vitis vinifera
TI:29760 None
 
G7JPL1_MEDTR
EnsemblPlants»
0.0
11441178 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Medicago truncatula
TI:3880 None
 
I1LPK1_SOYBN
EnsemblPlants»
0.0
LOC100803471 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Glycine max
TI:3847 None
 
K7LNX9_SOYBN
EnsemblPlants»
0.0
LOC100813256 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Glycine max
TI:3847 None
 
M4CAQ1_BRACM
EnsemblPlants»
0.0
non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Brassica campestris
TI:3711 None
   
M4CBD0_BRACM
EnsemblPlants»
0.0
non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Brassica campestris
TI:3711 None
   
M5XKP3_PRUPE
neXtProt»
0.0
PRUPE_1G346000 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Prunus persica
TI:3760 None
 
A0A0Q3HAC7_BRADI
EnsemblPlants»
0.0
LOC100822814 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Brachypodium distachyon
TI:15368 None
 
A0A1D6DV10_MAIZE
EnsemblPlants»
0.0
LOC100274088 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Zea mays
TI:4577 None
 
A0A1D6JGM5_MAIZE
EnsemblPlants»
0.0
LOC103642154 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Zea mays
TI:4577 None
 
A0A3B6B6T5_WHEAT
EnsemblPlants»
0.0
LOC123190670 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Triticum aestivum
TI:4565 None
   
A0A3B6CEA6_WHEAT
EnsemblPlants»
0.0
LOC123046993 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Triticum aestivum
TI:4565 None
   
A0A3B6DK15_WHEAT
EnsemblPlants»
0.0
non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Triticum aestivum
TI:4565 None
   
A0A8I7B416_HORVV
EnsemblPlants»
0.0
LOC123428050 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Hordeum vulgare
TI:4513 None
   
C5Y9L7_SORBI
neXtProt»
0.0
SORBI_3006G251000 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Sorghum bicolor
TI:4558 None
 
K3Z362_SETIT
EnsemblPlants»
0.0
LOC101769302 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Setaria italica
TI:4555 None
 
Q7XR00_ORYSJ
neXtProt»
0.0
Os04g0660500 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Oryza sativa
TI:4530 None
 
A0A804JK00_MUSAM
EnsemblPlants»
0.0
GSMUA_169050.1 non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Musa acuminata
TI:4641 None
 
A0A1U8LM06_GOSHI
neXtProt»
0.0
LOC107928881 MAP3K epsilon protein kinase 1 isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A1U8MGP9_GOSHI
euHCVdb»
0.0
LOC107937596 MAP3K epsilon protein kinase 1 isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A9R0JZU8_SPIOL
euHCVdb»
0.0
LOC110791998 MAP3K epsilon protein kinase 1 Spinacia oleracea
TI:3562 None
   
D8SB06_SELML
neXtProt»
0.0
SELMODRAFT_444546 Protein kinase domain-containing protein Selaginella moellendorffii
TI:88036 None
 
ARMC3_HUMAN
Ensembl»
1.5
ARMC3 Armadillo repeat-containing protein 3 (Beta-catenin-like
protein) (Cancer/testis antigen 81) (CT81) (KU-CT-1)		 Homo sapiens
TI:9606 None
 
A0ABM3AQU6_GOSHI
euHCVdb»
0.0
LOC107887759 MAP3K epsilon protein kinase 1 isoform X1 Gossypium hirsutum
TI:3635 None
   
ARMC3_MOUSE
Ensembl»
2.4
Armc3 Armadillo repeat-containing protein 3 Mus musculus
TI:10090 None
 
D8SMK9_SELML
neXtProt»
0.0
SELMODRAFT_423695 Protein kinase domain-containing protein Selaginella moellendorffii
TI:88036 None
 
M4FE75_BRACM
EnsemblPlants»
0.0
Protein kinase domain-containing protein Brassica campestris
TI:3711 None
   
A0ABM2ZQR3_GOSHI
neXtProt»
0.0
LOC107886900 MAP3K epsilon protein kinase 1 isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A804R9B8_MAIZE
EnsemblPlants»
0.0
LOC103639036 Importin N-terminal domain-containing protein Zea mays
TI:4577 None
   
A0A067F0Z7_CITSI
euHCVdb»
0.0
CISIN_1g0425011mg Protein kinase domain-containing protein Citrus sinensis
TI:2711 None
 
A0A0R0L6V6_SOYBN
EnsemblPlants»
0.0
GLYMA_02G215300 Protein kinase domain-containing protein Glycine max
TI:3847 None
 
A0A9K3EJ31_HELAN
neXtProt»
0.0
HanXRQr2_Chr13g0596481 Non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Helianthus annuus
TI:4232 None
 
A0A9K3HF83_HELAN
neXtProt»
0.0
HanXRQr2_Chr12g0533281 Non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Helianthus annuus
TI:4232 None
 
A0A9K3MZG7_HELAN
euHCVdb»
0.0
HanXRQr2_Chr11g0482541 Non-specific serine/threonine protein
kinase (EC 2.7.11.1)		 Helianthus annuus
TI:4232 None
 
A0A0A0LC86_CUCSA
euHCVdb»
0.0
Csa_3G654980 Protein kinase domain-containing protein Cucumis sativus
TI:3659 None
 
E7F083_DANRE
ZFIN»
0.0
armc3 Armadillo repeat-containing 3 (Armadillo
repeat-containing protein 3 isoform X1)		 Danio rerio
TI:7955 None
 
A0A022R4T5_ERYGU
euHCVdb»
0.0
MIMGU_mgv1a002152mg Uncharacterized protein Erythranthe guttata
TI:4155 None 		 
 
A0A078GB02_BRANA
euHCVdb»
0.0
BnaC05g39790D BnaC05g39790D protein Brassica napus
TI:3708 None 		 
 
A0A078J199_BRANA
euHCVdb»
0.0
BnaA05g37030D (rape) hypothetical
protein (BnaA05g37030D protein)		 Brassica napus
TI:3708 None 		 
 
A0A1D5R631_MACMU
Ensembl»
0.0
ARMC3 Armadillo repeat containing 3 Macaca mulatta
TI:9544 None 		     
A0A1L8FVH4_XENLA
Xenbase»
0.0
armc3.L Armadillo repeat-containing protein 3 Xenopus laevis
TI:8355 None 		     
A0A2I2Z9E3_GORGO
Ensembl»
0.0
ARMC3 Armadillo repeat containing 3 Gorilla gorilla
TI:9593 None 		 
 
A0A2I3RVQ5_PANTR
Ensembl»
0.0
ARMC3 Armadillo repeat containing 3 Pan troglodytes
TI:9598 None 		 
 
A0A2K2AE45_POPTR
euHCVdb»
0.0
POPTR_005G098200v4 Armadillo repeat-containing
domain-containing protein		 Populus trichocarpa
TI:3694 None 		 
 
A0A3N7F4D6_POPTR
neXtProt»
0.0
POPTR_005G094000 Uncharacterized protein Populus trichocarpa
TI:3694 None 		 
 
A0A3Q7H098_SOLLC
EnsemblPlants»
0.0
EDR1/CTR1/ARMC3-like peptidase-like
domain-containing protein		 Solanum lycopersicum
TI:4081 None 		     
A0A7M7NJ58_STRPU
EnsemblMetazoa»
0.0
Armadillo repeat-containing protein 3 Strongylocentrotus purpuratus
TI:7668 None 		     
A0A804N4Q4_MAIZE
EnsemblPlants»
0.0
Uncharacterized protein Zea mays
TI:4577 None 		     
A0A804QLR9_MAIZE
EnsemblPlants»
0.0
Uncharacterized protein Zea mays
TI:4577 None 		     
A0A8I3RTN5_CANLF
Ensembl»
0.0
ARMC3 Armadillo repeat containing 3 Canis lupus
TI:9612 None 		     
A0A8V0XNH0_CHICK
Ensembl»
0.0
ARMC3 Armadillo repeat containing 3 Gallus gallus
TI:9031 None 		     
A0A9J7L072_BRAFL
neXtProt»
0.0
LOC118413475 Armadillo repeat-containing protein 3-like Branchiostoma floridae
TI:7739 None 		     
A0A9L0S4T7_HORSE
Ensembl»
0.0
ARMC3 Armadillo repeat containing 3 Equus caballus
TI:9796 None 		     
A0ABI7Z6H1_FELCA
Ensembl»
0.0
ARMC3 Armadillo repeat containing 3 Felis catus
TI:9685 None 		     
A0ABK0LJ64_RAT
RGD»
0.0
Armc3 Armadillo repeat containing 3 Rattus norvegicus
TI:10116 None 		     
A2FSK7_TRIV3
TubercuList»
0.0
TVAG_226080 EDR1/CTR1/ARMC3-like peptidase-like
domain-containing protein		 Trichomonas vaginalis
TI:5722 None 		 
 
A7SCU6_NEMVE
neXtProt»
0.0
NEMVEDRAFT_v1g244371 Armadillo repeat-containing protein 3 Nematostella vectensis
TI:45351 None 		 
 
A9UV47_MONBE
euHCVdb»
0.0
MONBRDRAFT_31675 EDR1/CTR1/ARMC3-like peptidase-like
domain-containing protein		 Monosiga brevicollis
TI:81824 None 		 
 
B3RZC4_TRIAD
CTD»
0.0
TRIADDRAFT_57401 EDR1/CTR1/ARMC3-like peptidase-like
domain-containing protein		 Trichoplax adhaerens
TI:10228 None 		 
 
D6W9F3_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_00592 EDR1/CTR1/ARMC3-like peptidase-like
domain-containing protein		 Tribolium castaneum
TI:7070 None 		 
 
D8RMM1_SELML
neXtProt»
0.0
SELMODRAFT_96997 EDR1/CTR1/ARMC3-like peptidase-like
domain-containing protein		 Selaginella moellendorffii
TI:88036 None 		 
 
D8SLQ6_SELML
euHCVdb»
0.0
SELMODRAFT_119717 EDR1/CTR1/ARMC3-like peptidase-like
domain-containing protein		 Selaginella moellendorffii
TI:88036 None 		 
 
E1BPV0_BOVIN
Ensembl»
0.0
ARMC3 Armadillo repeat containing 3 Bos taurus
TI:9913 None 		     
F0ZTD1_DICPU
TubercuList»
0.0
DICPUDRAFT_155211 WW domain-containing protein Dictyostelium purpureum
TI:5786 None 		 
 
F1RVI7_PIG
Ensembl»
0.0
ARMC3 Armadillo repeat containing 3 Sus scrofa
TI:9823 None 		     
F4P3C6_BATDJ
neXtProt»
0.0
BATDEDRAFT_25027 EDR1/CTR1/ARMC3-like peptidase-like
domain-containing protein		 Batrachochytrium dendrobatidis
TI:109871 None 		 
 
F6YAM0_CIOIN
Ensembl»
0.0
Armadillo repeat-containing
domain-containing protein		 Ciona intestinalis
TI:7719 None 		 
 
F7BQA0_MONDO
Ensembl»
0.0
ARMC3 Armadillo repeat containing 3 Monodelphis domestica
TI:13616 None 		     
F7CLZ4_ORNAN
Ensembl»
0.0
ARMC3 Armadillo repeat containing 3 Ornithorhynchus anatinus
TI:9258 None 		     
G1KI48_ANOCA
Ensembl»
0.0
ARMC3 Armadillo repeat containing 3 Anolis carolinensis
TI:28377 None 		     
H2L3D2_ORYLA
Ensembl»
0.0
armc3 Armadillo repeat containing 3 Oryzias latipes
TI:8090 None 		     
M1ACK9_SOLTU
EnsemblPlants»
0.0
MAPKKK7 Solanum tuberosum
TI:4113 None 		     
M4EF62_BRACM
EnsemblPlants»
0.0
Uncharacterized protein Brassica campestris
TI:3711 None 		     
Q6NX16_XENTR
Xenbase»
0.0
armc3 Armadillo repeat-containing 3
(Armadillo repeat-containing protein 3)		 Xenopus tropicalis
TI:8364 None 		 
 
Q7JYM7_DROME
FlyBase»
0.0
Dmel\CG13326 GH11924p Drosophila melanogaster
TI:7227 None 		 
 
T1EVD9_HELRO
EnsemblMetazoa»
0.0
20200539 EDR1/CTR1/ARMC3-like peptidase-like
domain-containing protein		 Helobdella robusta
TI:6412 None 		 
 
W1NZA7_AMBTC
neXtProt»
0.0
AMTR_s00105p00071940 Uncharacterized protein Amborella trichopoda
TI:13333 None 		 
 
W5N1R4_LEPOC
Ensembl»
0.0
Armadillo repeat containing 3 Lepisosteus oculatus
TI:7918 None