Collated Gene Ontology terms

Biological process: unfolded protein binding(2013, 2017, 2025)

Molecular function: vacuolar proton-transporting V-type ATPase complex assembly2013, 2025 intracellular iron ion homeostasis2017, 2025 lysosomal protein catabolic process2017, 2025 lysosomal lumen acidification2017, 2025 cellular response to increased oxygen levels2017, 2025 vacuolar acidification2013, 2025

Cellular component: endoplasmic reticulum-Golgi intermediate compartment2016, 2025 COPI-coated vesicle2016, 2025 vacuole2025 lysosome2025 endosome2025 cytoplasmic vesicle2025 Vma12-Vma22 assembly complex2015, 2017, 2025 endoplasmic reticulum2012, 2017, 2025 vacuolar proton-transporting V-type ATPase complex2017, 2025 plasma membrane2024, 2025
nucleus2018 membrane2014

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 11/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 1/3 
Excavates: 0/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 35/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A4X1SE54_PIG
Ensembl»
0.0
CCDC115 Vacuolar ATPase assembly protein
VMA22 (Coiled-coil domain-containing protein 115)		 Sus scrofa
TI:9823 None
 
Q9LM77_ARATH
TAIR»
0.5
At1g20770 Vacuolar ATPase assembly protein VMA22 Arabidopsis thaliana
TI:3702 None
 
VMA22_HUMAN
Ensembl»
3.7
VMA22 Vacuolar ATPase assembly protein
VMA22 (Coiled-coil domain-containing protein 115)		 Homo sapiens
TI:9606 None
 
A0A2K2AME7_POPTR
euHCVdb»
0.0
POPTR_005G253100 Vacuolar ATPase assembly protein VMA22 Populus trichocarpa
TI:3694 None
 
C5YBY3_SORBI
neXtProt»
0.0
SORBI_3006G142700 Vacuolar ATPase assembly protein VMA22 Sorghum bicolor
TI:4558 None
 
Q9VND4_DROME
FlyBase»
0.5
Dmel\CG14671 Vacuolar ATPase assembly protein VMA22 Drosophila melanogaster
TI:7227 None
 
VMA22_YEAST
SGD»
2.9
VMA22 Vacuolar ATPase assembly protein VMA22 Saccharomyces cerevisiae
TI:4932 None
 
A0A078H4T8_BRANA
euHCVdb»
0.0
BnaC07g15180D (rape) hypothetical
protein (BnaC07g15180D protein)		 Brassica napus
TI:3708 None
 
A0A251RZV6_HELAN
euHCVdb»
0.0
HannXRQ_Chr16g0516421 HanXRQr2_Chr16g0755071 Vacuolar ATPase assembly protein VMA22 Helianthus annuus
TI:4232 None
 
B7PKM0_IXOSC
EnsemblMetazoa»
0.0
8051923 Vacuolar ATPase assembly protein VMA22 Ixodes scapularis
TI:6945 None
 
I1JNP4_SOYBN
EnsemblPlants»
0.0
LOC100306518 Vacuolar ATPase assembly protein VMA22 Glycine max
TI:3847 None
 
K3Y9V1_SETIT
EnsemblPlants»
0.0
LOC101766167 Vacuolar ATPase assembly protein VMA22 Setaria italica
TI:4555 None
 
Q7XQ15_ORYSJ
neXtProt»
0.0
Os04g0509200 Vacuolar ATPase assembly protein VMA22 Oryza sativa
TI:4530 None
 
Q9VUE9_DROME
FlyBase»
0.5
Dmel\CG9592 Vacuolar ATPase assembly protein VMA22 Drosophila melanogaster
TI:7227 None
 
T1F3N1_HELRO
EnsemblMetazoa»
0.0
20203430 Vacuolar ATPase assembly protein VMA22 Helobdella robusta
TI:6412 None
 
VMA22_MOUSE
Ensembl»
2.5
Vma22 Vacuolar ATPase assembly protein VMA22 (Coiled-coil
domain-containing protein 115) (Coiled-coil protein 1) (Ccp1)		 Mus musculus
TI:10090 None
 
A0A022Q3J2_ERYGU
euHCVdb»
0.0
MIMGU_mgv1a016228mg Vacuolar ATPase assembly protein VMA22 Erythranthe guttata
TI:4155 None
 
A0A022Q5I1_ERYGU
euHCVdb»
0.0
MIMGU_mgv1a019828mg Vacuolar ATPase assembly protein VMA22 Erythranthe guttata
TI:4155 None
 
A0A022QUN4_ERYGU
euHCVdb»
0.0
MIMGU_mgv1a013147mg Vacuolar ATPase assembly protein VMA22 Erythranthe guttata
TI:4155 None
 
A0A022RCE1_ERYGU
neXtProt»
0.0
MIMGU_mgv1a014153mg Vacuolar ATPase assembly protein VMA22 Erythranthe guttata
TI:4155 None
 
A0A061FDB5_THECC
euHCVdb»
0.0
TCM_034415 Vacuolar ATPase assembly protein VMA22 Theobroma cacao
TI:3641 None
 
A0A067H2K7_CITSI
euHCVdb»
0.0
CISIN_1g028552mg Vacuolar ATPase assembly protein VMA22 Citrus sinensis
TI:2711 None
 
A0A072VDW6_MEDTR
EnsemblPlants»
0.0
25490325 Vacuolar ATPase assembly protein VMA22 Medicago truncatula
TI:3880 None
 
A0A078H4Y2_BRANA
euHCVdb»
0.0
BnaC08g19450D Vacuolar ATPase assembly protein VMA22 Brassica napus
TI:3708 None
 
A0A0A0L4M6_CUCSA
neXtProt»
0.0
Csa_4G664250 Vacuolar ATPase assembly protein VMA22 Cucumis sativus
TI:3659 None
 
A0A0K9NLW1_ZOSMR
euHCVdb»
0.0
ZOSMA_82G00510 Vacuolar ATPase assembly protein VMA22 Zostera marina
TI:29655 None
 
A0A1D8PU20_CANAL
CGD»
0.0
VMA22 Vacuolar ATPase assembly protein VMA22 Candida albicans
TI:5476 None
 
A0A1U8FQA1_CAPAN
neXtProt»
0.0
T459_06986 Vacuolar ATPase assembly protein VMA22 Capsicum annuum
TI:4072 None
 
A0A2K1J573_PHYPA
EnsemblPlants»
0.0
LOC112294879 Vacuolar ATPase assembly protein VMA22 Physcomitrium patens
TI:3218 None
 
A0A2K3DGR6_CHLRE
euHCVdb»
0.0
CHLRE_08g363800v5 Vacuolar ATPase assembly protein VMA22 Chlamydomonas reinhardtii
TI:3055 None
 
A0A2R6W1C3_MARPO
euHCVdb»
0.0
MARPO_0189s0009 Vacuolar ATPase assembly protein VMA22 Marchantia polymorpha
TI:3197 None
 
A0A368UHC5_SOYBN
EnsemblPlants»
0.0
GLYMA_19G151500 Vacuolar ATPase assembly protein VMA22 Glycine max
TI:3847 None
 
A0A7U2ERV7_PHANO
TubercuList»
0.0
JI435_003310 Vacuolar ATPase assembly protein VMA22 Phaeosphaeria nodorum
TI:13684 None
 
A0A804ISY7_MUSAM
EnsemblPlants»
0.0
GSMUA_129340.1 Vacuolar ATPase assembly protein VMA22 Musa acuminata
TI:4641 None
 
A0A9R1W8V5_LACSA
neXtProt»
0.0
LSAT_V11C200051620 Vacuolar ATPase assembly protein VMA22 Lactuca sativa
TI:4236 None
 
A4D9G1_ASPFU
TubercuList»
0.0
AFUA_3G06495 Vacuolar ATPase assembly protein VMA22 Aspergillus fumigatus
TI:746128 None
 
A7F7Z7_SCLS1
TubercuList»
0.0
SS1G_13727 Vacuolar ATPase assembly protein VMA22 Sclerotinia sclerotiorum
TI:5180 None
 
A7S2I2_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g27934 Vacuolar ATPase assembly protein
VMA22 (Coiled-coil domain-containing protein 115)		 Nematostella vectensis
TI:45351 None
 
A7T701_NEMVE
neXtProt»
0.0
NEMVEDRAFT_v1g4564 Vacuolar ATPase assembly protein
VMA22 (Coiled-coil domain-containing protein 115)		 Nematostella vectensis
TI:45351 None
 
A7UWS7_NEUCR
TubercuList»
0.0
NCU11319 Vacuolar ATPase assembly protein VMA22 Neurospora crassa
TI:5141 None
 
A8XGE9_CAEBR
WormBase»
0.0
CBG12719 CBG_12719 Vacuolar ATPase assembly protein VMA22 Caenorhabditis briggsae
TI:6238 None
 
B3RUI2_TRIAD
CTD»
0.0
TRIADDRAFT_55299 Vacuolar ATPase assembly protein VMA22 Trichoplax adhaerens
TI:10228 None
 
B8BYN4_THAPS
euHCVdb»
0.0
THAPSDRAFT_21904 Vacuolar ATPase assembly protein VMA22 Thalassiosira pseudonana
TI:35128 None
 
B9R8Q4_RICCO
euHCVdb»
0.0
RCOM_1601630 Vacuolar ATPase assembly protein VMA22 Ricinus communis
TI:3988 None
 
D6WY99_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_02222 Vacuolar ATPase assembly protein VMA22 Tribolium castaneum
TI:7070 None
 
D7UDC0_VITVI
euHCVdb»
0.0
VIT_18s0122g01060 Vacuolar ATPase assembly protein VMA22 Vitis vinifera
TI:29760 None
 
E3KZD2_PUCGT
TubercuList»
0.0
PGTG_15620 Vacuolar ATPase assembly protein VMA22 Puccinia graminis
TI:5297 None
 
F4NRU0_BATDJ
euHCVdb»
0.0
BATDEDRAFT_22010 Vacuolar ATPase assembly protein VMA22 Batrachochytrium dendrobatidis
TI:109871 None
 
G3QGV5_GORGO
Ensembl»
0.0
CCDC115 Vacuolar ATPase assembly protein VMA22 Gorilla gorilla
TI:9593 None
 
H2QIQ1_PANTR
Ensembl»
0.0
CCDC115 Vacuolar ATPase assembly protein VMA22 Pan troglodytes
TI:9598 None
 
I1IZI4_BRADI
EnsemblPlants»
0.0
LOC100834673 Vacuolar ATPase assembly protein VMA22 Brachypodium distachyon
TI:15368 None
 
K3ZJP6_SETIT
EnsemblPlants»
0.0
Vacuolar ATPase assembly protein VMA22 Setaria italica
TI:4555 None
 
M5XLX3_PRUPE
euHCVdb»
0.0
PRUPE_2G140800 Vacuolar ATPase assembly protein VMA22 Prunus persica
TI:3760 None
 
O01314_CAEEL
WormBase»
0.5
CELE_F02E9.1 F02E9.1 Vacuolar ATPase assembly protein VMA22 Caenorhabditis elegans
TI:6239 None
 
Q380Q2_ANOGA
EnsemblMetazoa»
0.0
3290532 Vacuolar ATPase assembly protein VMA22 Anopheles gambiae
TI:7165 None
 
Q555R1_DICDI
dictyBase»
0.5
DDB_G0274723 Vacuolar ATPase assembly protein VMA22 Dictyostelium discoideum
TI:44689 None
 
Q5B3W4_EMENI
TubercuList»
0.0
ANIA_04766 Vacuolar ATPase assembly protein VMA22 Emericella nidulans
TI:162425 None
 
Q6C5U7_YARLI
TubercuList»
0.0
YALI0_E15059g Vacuolar ATPase assembly protein VMA22 Yarrowia lipolytica
TI:4952 None
 
Q75EX6_EREGS
euHCVdb»
0.0
AGOS_AAL048W Vacuolar ATPase assembly protein VMA22 Eremothecium gossypii
TI:33169 None
 
U5D9X3_AMBTC
euHCVdb»
0.0
AMTR_s00044p00148630 Vacuolar ATPase assembly protein VMA22 Amborella trichopoda
TI:13333 None
 
VMA22_BOVIN
CTD»
0.0
VMA22 Vacuolar ATPase assembly protein
VMA22 (Coiled-coil domain-containing protein 115)		 Bos taurus
TI:9913 None
 
VMA22_DANRE
ZFIN»
1.0
vma22 Vacuolar ATPase assembly protein
VMA22 (Coiled-coil domain-containing protein 115)		 Danio rerio
TI:7955 None
 
W5NAT6_LEPOC
Ensembl»
0.0
Vacuolar ATPase assembly protein
VMA22 (Coiled-coil domain-containing protein 115)		 Lepisosteus oculatus
TI:7918 None
 
A0A1D5USC8_WHEAT
EnsemblPlants»
0.0
LOC123053876 Vacuolar ATPase assembly protein VMA22 Triticum aestivum
TI:4565 None
   
A0A1L8EZQ4_XENLA
CTD»
0.0
XB5795058.S Vacuolar ATPase assembly protein
VMA22 (Coiled-coil domain-containing protein 115)		 Xenopus laevis
TI:8355 None
   
A0A1U8AGH9_NELNU
euHCVdb»
0.0
LOC104603782 Vacuolar ATPase assembly protein VMA22 Nelumbo nucifera
TI:4432 None
   
A0A1U8B4U6_NELNU
euHCVdb»
0.0
LOC104607252 Vacuolar ATPase assembly protein VMA22 Nelumbo nucifera
TI:4432 None
   
A0A1U8KVA2_GOSHI
euHCVdb»
0.0
LOC107921047 Vacuolar ATPase assembly protein VMA22 Gossypium hirsutum
TI:3635 None
   
A0A1U8N6B6_GOSHI
euHCVdb»
0.0
LOC107945242 Vacuolar ATPase assembly protein VMA22 Gossypium hirsutum
TI:3635 None
   
A0A2I4HWY3_JUGRE
euHCVdb»
0.0
LOC109022236 Vacuolar ATPase assembly protein VMA22 Juglans regia
TI:51240 None
   
A0A3B5Y2T0_WHEAT
EnsemblPlants»
0.0
LOC123154503 Vacuolar ATPase assembly protein VMA22 Triticum aestivum
TI:4565 None
   
A0A3B5Z056_WHEAT
EnsemblPlants»
0.0
LOC123136447 Vacuolar ATPase assembly protein VMA22 Triticum aestivum
TI:4565 None
   
A0A3B5ZYR2_WHEAT
EnsemblPlants»
0.0
LOC123182302 Vacuolar ATPase assembly protein VMA22 Triticum aestivum
TI:4565 None
   
A0A3B6B114_WHEAT
EnsemblPlants»
0.0
LOC123189745 Vacuolar ATPase assembly protein VMA22 Triticum aestivum
TI:4565 None
   
A0A3B6C9J6_WHEAT
EnsemblPlants»
0.0
LOC123046004 Vacuolar ATPase assembly protein VMA22 Triticum aestivum
TI:4565 None
   
A0A3Q7FAD8_SOLLC
EnsemblPlants»
0.0
LOC101253850 Vacuolar ATPase assembly protein VMA22 Solanum lycopersicum
TI:4081 None
   
A0A5F8AJX8_MACMU
Ensembl»
0.0
CCDC115 Vacuolar ATPase assembly protein
VMA22 (Coiled-coil domain-containing protein 115)		 Macaca mulatta
TI:9544 None
   
A0A6I8NGF8_ORNAN
Ensembl»
0.0
CCDC115 Vacuolar ATPase assembly protein VMA22 Ornithorhynchus anatinus
TI:9258 None
   
A0A6I8SI89_XENTR
Xenbase»
0.0
vma22 Vacuolar ATPase assembly protein
VMA22 (Coiled-coil domain-containing protein 115)		 Xenopus tropicalis
TI:8364 None
   
A0A7M7MXF3_STRPU
EnsemblMetazoa»
0.0
Vacuolar ATPase assembly protein VMA22 Strongylocentrotus purpuratus
TI:7668 None
   
A0A803TRZ6_ANOCA
Ensembl»
0.0
ccdc115 Vacuolar ATPase assembly protein
VMA22 (Coiled-coil domain-containing protein 115)		 Anolis carolinensis
TI:28377 None
   
A0A804MDN2_MAIZE
EnsemblPlants»
0.0
Vacuolar ATPase assembly protein VMA22 Zea mays
TI:4577 None
   
A0A804P3C0_MAIZE
EnsemblPlants»
0.0
Vacuolar ATPase assembly protein VMA22 Zea mays
TI:4577 None
   
A0A8I3PPL8_CANLF
Ensembl»
0.0
CCDC115 Vacuolar ATPase assembly protein
VMA22 (Coiled-coil domain-containing protein 115)		 Canis lupus
TI:9612 None
   
A0A9J7MQV5_BRAFL
neXtProt»
0.0
LOC118415345 Vacuolar ATPase assembly protein VMA22 Branchiostoma floridae
TI:7739 None
   
A0A9R0J2R1_SPIOL
euHCVdb»
0.0
LOC110798088 Vacuolar ATPase assembly protein VMA22 Spinacia oleracea
TI:3562 None
   
A0AAF6YKL8_BOVIN
Ensembl»
0.0
CCDC115 Vacuolar ATPase assembly protein
VMA22 (Coiled-coil domain-containing protein 115)		 Bos taurus
TI:9913 None
   
A0ABI7Z8B6_FELCA
Ensembl»
0.0
CCDC115 Vacuolar ATPase assembly protein VMA22 Felis catus
TI:9685 None
   
B2GV96_RAT
RGD»
2.5
Ccdc115 Vacuolar ATPase assembly protein
VMA22 (Coiled-coil domain-containing protein 115)		 Rattus norvegicus
TI:10116 None
   
F6PPS8_MONDO
Ensembl»
0.0
Vacuolar ATPase assembly protein VMA22 Monodelphis domestica
TI:13616 None
   
F6YV01_HORSE
Ensembl»
0.0
CCDC115 Vacuolar ATPase assembly protein VMA22 Equus caballus
TI:9796 None
   
F7GHS8_MONDO
Ensembl»
0.0
CCDC115 Vacuolar ATPase assembly protein VMA22 Monodelphis domestica
TI:13616 None
   
H2LVU5_ORYLA
Ensembl»
0.0
ccdc115 Vacuolar ATPase assembly protein
VMA22 (Coiled-coil domain-containing protein 115)		 Oryzias latipes
TI:8090 None
   
M0WXZ8_HORVV
EnsemblPlants»
0.0
LOC123427215 Vacuolar ATPase assembly protein VMA22 Hordeum vulgare
TI:4513 None
   
M0ZLH5_SOLTU
EnsemblPlants»
0.0
LOC102584984 Vacuolar ATPase assembly protein VMA22 Solanum tuberosum
TI:4113 None
   
M4D6Y8_BRACM
EnsemblPlants»
0.0
Coiled-coil domain-containing protein 115 Brassica campestris
TI:3711 None
   
M4DIX7_BRACM
EnsemblPlants»
0.0
Vacuolar ATPase assembly protein VMA22 Brassica campestris
TI:3711 None