Collated Gene Ontology terms

Biological process: catalytic activity(2025)

Molecular function: positive regulation of DNA-templated transcription2017, 2020, 2025 DNA-templated transcription2025 signal transduction2025

Cellular component: nucleus2018, 2025 cytoplasm2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 2/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 36/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A1S4GC94_ANOGA
EnsemblMetazoa»
0.0
Uncharacterized protein Anopheles gambiae
TI:7165 None
 
A0A1S4KVY6_IXOSC
EnsemblMetazoa»
0.0
Erythroid differentiation-related factor 1 Ixodes scapularis
TI:6945 None
 
A0A3B6GZF2_WHEAT
EnsemblPlants»
0.0
EDRF1 N-terminal domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3Q7GWM5_SOLLC
EnsemblPlants»
0.0
EDRF1 N-terminal domain-containing protein Solanum lycopersicum
TI:4081 None
   
A0A3Q7GYV9_SOLLC
EnsemblPlants»
0.0
Uncharacterized protein Solanum lycopersicum
TI:4081 None 		       
A0A7M7N2B3_STRPU
EnsemblMetazoa»
0.0
EDRF1 TPR repeats
region domain-containing protein		 Strongylocentrotus purpuratus
TI:7668 None 		     
A0A7M7NLM3_STRPU
EnsemblMetazoa»
0.0
Erythroid differentiation-related factor 1 Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7STK4_STRPU
EnsemblMetazoa»
0.0
EDRF1 TPR repeats
region domain-containing protein		 Strongylocentrotus purpuratus
TI:7668 None 		     
F6UHR3_CIOIN
Ensembl»
0.0
Erythroid differentiation-related factor 1 Ciona intestinalis
TI:7719 None
 
H3GX18_PHYRM
EnsemblProtists»
0.0
EDRF1 N-terminal domain-containing protein Phytophthora ramorum
TI:164328 None 		 
 
M4DQY0_BRACM
EnsemblPlants»
0.0
EDRF1 N-terminal domain-containing protein Brassica campestris
TI:3711 None
   
W5MML0_LEPOC
Ensembl»
0.0
Erythroid differentiation regulatory factor 1 Lepisosteus oculatus
TI:7918 None
 
G7I7V1_MEDTR
EnsemblPlants»
0.0
11423949 Erythroid differentiation-related
factor 1, putative		 Medicago truncatula
TI:3880 None
 
T1F6K1_HELRO
EnsemblMetazoa»
0.0
20204450 Uncharacterized protein Helobdella robusta
TI:6412 None
 
T1F6K2_HELRO
EnsemblMetazoa»
0.0
20204451 EDRF1 N-terminal domain-containing protein Helobdella robusta
TI:6412 None 		 
 
W1P3W8_AMBTC
neXtProt»
0.0
AMTR_s00090p00110300 Uncharacterized protein Amborella trichopoda
TI:13333 None 		 
   
W1NZC7_AMBTC
euHCVdb»
0.0
AMTR_s00134p00078680 EDRF1 N-terminal domain-containing protein Amborella trichopoda
TI:13333 None
 
D6WC98_TRICA
neXtProt»
0.0
AUGUSTUS-3.0.2_00196 Erythroid differentiation-related
factor 1-like Protein		 Tribolium castaneum
TI:7070 None
 
F4HZZ6_ARATH
TAIR»
0.5
At1g35660 Erythroid differentiation factor-like protein Arabidopsis thaliana
TI:3702 None
 
A0A078GBZ0_BRANA
euHCVdb»
0.0
BnaA06g02180D BnaA06g02180D protein Brassica napus
TI:3708 None
 
A0A078H8R2_BRANA
euHCVdb»
0.0
BnaC06g04740D (rape) hypothetical
protein (BnaC06g04740D protein)		 Brassica napus
TI:3708 None
 
A0A067H849_CITSI
euHCVdb»
0.0
CISIN_1g000487mg EDRF1 N-terminal domain-containing protein Citrus sinensis
TI:2711 None
 
A0A0A0LQ13_CUCSA
euHCVdb»
0.0
Csa_2G402120 EDRF1 N-terminal domain-containing protein Cucumis sativus
TI:3659 None
 
E9GMK3_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_104540 Uncharacterized protein Daphnia pulex
TI:6669 None
 
E9HYQ1_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_119506 Uncharacterized protein Daphnia pulex
TI:6669 None
 
E9GN10_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_225243 Erythroid differentiation-related factor 1 Daphnia pulex
TI:6669 None
 
E9HSW6_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_265116 EDRF1 N-terminal domain-containing protein Daphnia pulex
TI:6669 None 		 
 
E9G075_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_312245 Erythroid differentiation-related factor 1 Daphnia pulex
TI:6669 None
 
E9HSQ5_DAPPU
neXtProt»
0.0
DAPPUDRAFT_333401 Uncharacterized protein Daphnia pulex
TI:6669 None 		 
   
E9I2Q0_DAPPU
neXtProt»
0.0
DAPPUDRAFT_338334 EDRF1 N-terminal domain-containing protein Daphnia pulex
TI:6669 None 		 
 
Q9VSP0_DROME
FlyBase»
0.5
Dmel\CG6511 IP13783p Drosophila melanogaster
TI:7227 None
 
A0A3B3HFU6_ORYLA
Ensembl»
0.0
EDRF1 Erythroid differentiation regulatory factor 1 Oryzias latipes
TI:8090 None
   
A0A803T752_ANOCA
Ensembl»
0.0
EDRF1 Erythroid differentiation regulatory factor 1 Anolis carolinensis
TI:28377 None
   
A0A8I3PZQ0_CANLF
Ensembl»
0.0
EDRF1 Erythroid differentiation regulatory factor 1 Canis lupus
TI:9612 None
   
A0A8V0XFQ7_CHICK
Ensembl»
0.5
EDRF1 Erythroid differentiation regulatory factor 1 Gallus gallus
TI:9031 None
   
A0AAA9TFU8_BOVIN
Ensembl»
0.0
EDRF1 Erythroid differentiation regulatory factor 1 Bos taurus
TI:9913 None
   
A0ABI7WZ67_FELCA
Ensembl»
0.0
EDRF1 Erythroid differentiation regulatory factor 1 Felis catus
TI:9685 None 		     
EDRF1_HUMAN
Ensembl»
1.3
EDRF1 Erythroid differentiation-related factor 1 Homo sapiens
TI:9606 None
 
F1SDM8_PIG
Ensembl»
0.0
EDRF1 Erythroid differentiation regulatory factor 1 Sus scrofa
TI:9823 None
   
F6WBY1_MACMU
Ensembl»
0.0
EDRF1 Erythroid differentiation regulatory factor 1 Macaca mulatta
TI:9544 None
   
F7A6W7_MONDO
Ensembl»
0.0
EDRF1 Erythroid differentiation regulatory factor 1 Monodelphis domestica
TI:13616 None
   
F7C777_ORNAN
Ensembl»
0.0
EDRF1 Erythroid differentiation regulatory factor 1 Ornithorhynchus anatinus
TI:9258 None
   
F7CXF6_HORSE
Ensembl»
0.0
EDRF1 Erythroid differentiation regulatory factor 1 Equus caballus
TI:9796 None 		     
G3S182_GORGO
Ensembl»
0.0
EDRF1 Erythroid differentiation regulatory factor 1 Gorilla gorilla
TI:9593 None
 
K7DL11_PANTR
Ensembl»
0.0
EDRF1 Chromosome 10 open reading frame
137 (Erythroid differentiation regulatory factor 1)		 Pan troglodytes
TI:9598 None
 
A0A0G2K4K6_RAT
RGD»
1.0
Edrf1 Erythroid differentiation regulatory factor 1 Rattus norvegicus
TI:10116 None
   
EDRF1_MOUSE
AG»
1.0
Edrf1 Erythroid differentiation-related factor 1 Mus musculus
TI:10090 None
 
A0A804JI89_MUSAM
EnsemblPlants»
0.0
GSMUA_166010.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0A251UZF4_HELAN
neXtProt»
0.0
HannXRQ_Chr04g0107521 HanXRQr2_Chr04g0156791 Tetratricopeptide-like helical
domain superfamily		 Helianthus annuus
TI:4232 None
 
A0A0U9HJ68_KLENI
euHCVdb»
0.0
KFL_000750050 EDRF1 N-terminal domain-containing protein Klebsormidium nitens
TI:105231 None
 
Q4QHA1_LEIMA
TubercuList»
0.0
LMJF_10_1130 Clu domain-containing protein Leishmania major
TI:5664 None
   
K7K8N1_SOYBN
EnsemblPlants»
0.0
LOC100780584 EDRF1 N-terminal domain-containing protein Glycine max
TI:3847 None
 
I1HTV5_BRADI
EnsemblPlants»
0.0
LOC100837056 EDRF1 N-terminal domain-containing protein Brachypodium distachyon
TI:15368 None
 
K3XDT7_SETIT
EnsemblPlants»
0.0
LOC101770980 EDRF1 N-terminal domain-containing protein Setaria italica
TI:4555 None
 
A0A1D6N5Y2_MAIZE
EnsemblPlants»
0.0
LOC103650944 Erythroid differentiation-related
factor 1-like protein		 Zea mays
TI:4577 None
 
A0A1U7ZFS7_NELNU
euHCVdb»
0.0
LOC104590084 Uncharacterized protein LOC104590084 Nelumbo nucifera
TI:4432 None
   
A0A1S3Z178_TOBAC
euHCVdb»
0.0
LOC107781912 Uncharacterized protein isoform X1 Nicotiana tabacum
TI:4097 None
   
A0A1S3ZPE8_TOBAC
euHCVdb»
0.0
LOC107789148 Uncharacterized protein isoform X1 Nicotiana tabacum
TI:4097 None
   
A0A1U8K6X0_GOSHI
euHCVdb»
0.0
LOC107914042 EDRF1 N-terminal domain-containing protein Gossypium hirsutum
TI:3635 None
   
A0A2I4GXR9_JUGRE
euHCVdb»
0.0
LOC109011805 Uncharacterized protein LOC109011805 Juglans regia
TI:51240 None
   
A0A9R0JCN4_SPIOL
neXtProt»
0.0
LOC110802933 EDRF1 N-terminal domain-containing protein Spinacia oleracea
TI:3562 None
   
A0A7I4AZU9_PHYPA
EnsemblPlants»
0.0
LOC112292928 EDRF1 N-terminal domain-containing protein Physcomitrium patens
TI:3218 None
 
A0A9J7MLW9_BRAFL
euHCVdb»
0.0
LOC118413371 Erythroid differentiation-related factor
1-like isoform X1		 Branchiostoma floridae
TI:7739 None
   
A0A3B6EN02_WHEAT
EnsemblPlants»
0.0
LOC123071585 EDRF1 N-terminal domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6FU14_WHEAT
EnsemblPlants»
0.0
LOC123079924 EDRF1 N-terminal domain-containing protein Triticum aestivum
TI:4565 None
   
A0A8I6XH09_HORVV
EnsemblPlants»
0.0
LOC123444765 EDRF1 N-terminal domain-containing protein Hordeum vulgare
TI:4513 None
   
A0A9R1WGM1_LACSA
euHCVdb»
0.0
LSAT_V11C100005020 EDRF1 N-terminal domain-containing protein Lactuca sativa
TI:4236 None
 
A0A251IS71_MANES
euHCVdb»
0.0
MANES_18G101200 EDRF1 N-terminal domain-containing protein Manihot esculenta
TI:3983 None
 
A0A2R6X4Z6_MARPO
euHCVdb»
0.0
MARPO_0036s0148 Erythroid differentiation-related factor 1 Marchantia polymorpha
TI:3197 None
 
A0A022Q4B9_ERYGU
euHCVdb»
0.0
MIMGU_mgv1a000221mg EDRF1 N-terminal domain-containing protein Erythranthe guttata
TI:4155 None
 
A9UP92_MONBE
neXtProt»
0.0
MONBRDRAFT_22004 Rho-GAP domain-containing protein Monosiga brevicollis
TI:81824 None
 
A7RIB2_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g197539 EDRF1 N-terminal domain-containing protein Nematostella vectensis
TI:45351 None
 
A7RIB1_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g30728 EDRF1 TPR repeats
region domain-containing protein		 Nematostella vectensis
TI:45351 None
 
Q5N730_ORYSJ
euHCVdb»
0.0
Os01g0873800 Os01g0873800 protein Oryza sativa
TI:4530 None
 
A0A2K1WRG6_POPTR
euHCVdb»
0.0
POPTR_019G083100 EDRF1 N-terminal domain-containing protein Populus trichocarpa
TI:3694 None
 
A0A251MTS0_PRUPE
euHCVdb»
0.0
PRUPE_8G057200 EDRF1 N-terminal domain-containing protein Prunus persica
TI:3760 None
 
B9SLE4_RICCO
neXtProt»
0.0
RCOM_0685910 EDRF1 N-terminal domain-containing protein Ricinus communis
TI:3988 None
 
C5XRB0_SORBI
neXtProt»
0.0
SORBI_3003G372700 EDRF1 N-terminal domain-containing protein Sorghum bicolor
TI:4558 None
 
A0A1U8GUE4_CAPAN
euHCVdb»
0.0
T459_17190 EDRF1 N-terminal domain-containing protein Capsicum annuum
TI:4072 None
 
A0A061FK10_THECC
euHCVdb»
0.0
TCM_036370 Erythroid differentiation-related factor 1 Theobroma cacao
TI:3641 None
 
B8CE65_THAPS
euHCVdb»
0.0
THAPSDRAFT_25267 Uncharacterized protein Thalassiosira pseudonana
TI:35128 None
 
B3SBW4_TRIAD
CTD»
0.0
TRIADDRAFT_61759 EDRF1 TPR repeats
region domain-containing protein		 Trichoplax adhaerens
TI:10228 None 		 
 
B3SBW5_TRIAD
CTD»
0.0
TRIADDRAFT_61760 EDRF1 N-terminal domain-containing protein Trichoplax adhaerens
TI:10228 None 		 
 
Q57UZ5_TRYB2
TubercuList»
0.0
Tb08.4A8.160 EDRF1 N-terminal domain-containing protein Trypanosoma brucei
TI:5691 None
 
F6GY04_VITVI
neXtProt»
0.0
VIT_18s0072g01150 EDRF1 N-terminal domain-containing protein Vitis vinifera
TI:29760 None
 
A0A0K9NSG2_ZOSMR
euHCVdb»
0.0
ZOSMA_65G00330 Erythroid differentiation-related
factor 1-like protein		 Zostera marina
TI:29655 None
 
A0A0R4IK17_DANRE
ZFIN»
0.5
edrf1 Erythroid differentiation regulatory factor 1
(Erythroid differentiation-related factor 1 isoform X1)		 Danio rerio
TI:7955 None
 
A0A8J0SGI9_XENTR
Xenbase»
0.0
edrf1 Erythroid differentiation-related factor
1 isoform X2		 Xenopus tropicalis
TI:8364 None
   
A0A1L8FEG7_XENLA
Xenbase»
0.0
edrf1.S Uncharacterized protein LOC432052 isoform X1 Xenopus laevis
TI:8355 None