Collated Gene Ontology terms

Biological process: RNA binding(2013, 2014, 2015, 2023, 2024) poly(U) RNA binding(2017, 2024) U2 snRNA binding(2023, 2024) small GTPase binding(2014, 2024) protein kinase binding(2011) tRNA-intron endonuclease activity(2024) U6 snRNA binding(2003) RNA folding chaperone(2023)

Molecular function: mRNA splicing, via spliceosome2006, 2010, 2011, 2015, 2016, 2017, 2018, 2019, 2020, 2022, 2024 mRNA processing2024 RNA splicing2024 deadenylation-dependent decapping of nuclear-transcribed mRNA2015, 2017, 2024 tRNA processing2015, 2024 rRNA processing2015, 2024 spliceosomal tri-snRNP complex assembly2019, 2024 mRNA catabolic process2019, 2024 translation2021 telomerase holoenzyme complex assembly2018
tRNA splicing, via endonucleolytic cleavage and ligation2024 regulation of alternative mRNA splicing, via spliceosome2006 RNA folding2024

Cellular component: U4/U6 x U5 tri-snRNP complex2006, 2013, 2016, 2018, 2019, 2020, 2022, 2024 nucleus2006, 2015, 2016, 2017, 2018, 2022, 2024 U6 snRNP2006, 2015, 2016, 2023, 2024 Lsm1-7-Pat1 complex2015, 2017, 2023, 2024 spliceosomal complex2006, 2016, 2024 P-body2015, 2017, 2024 catalytic step 2 spliceosome2010, 2011, 2017, 2024 precatalytic spliceosome2010, 2017, 2024 Lsm2-8 complex2017, 2018, 2023, 2024 cytoplasm2018, 2019, 2024
protein-containing complex2024 nucleolus2005, 2006, 2015, 2024 sno(s)RNA-containing ribonucleoprotein complex2019, 2024 U5 snRNP2023, 2024 U2-type precatalytic spliceosome2018, 2024 nucleoplasm2013, 2023, 2024 telomerase holoenzyme complex2022 small nuclear ribonucleoprotein complex2006 membrane2024 cytosol2013 U4/U6 snRNP2016 U2 snRNP2023

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 1/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 34/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
LSM2_HUMAN
Ensembl»
6.9
LSM2 U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (Small nuclear
ribonuclear protein D homolog) (snRNP core Sm-like protein Sm-x5)		 Homo sapiens
TI:9606 None
 
H2QSP4_PANTR
Ensembl»
0.0
LSM2 U6 snRNA-associated Sm-like protein LSm2 Pan troglodytes
TI:9598 None
 
LSM2_ARATH
TAIR»
2.2
LSM2 Sm-like protein LSM2 (AtLSM2)
(U6 snRNA-associated Sm-like protein LSM2)		 Arabidopsis thaliana
TI:3702 None
 
LSM2_MOUSE
Ensembl»
2.3
Lsm2 U6 snRNA-associated Sm-like protein LSm2 (Protein
G7b) (snRNP core Sm-like protein Sm-x5)		 Mus musculus
TI:10090 None
 
Q5RKP8_DANRE
ZFIN»
1.0
lsm2 U6 snRNA-associated Sm-like protein LSm2 Danio rerio
TI:7955 None
 
A0A194YPX4_SORBI
EnsemblPlants»
0.0
SORBI_3004G156400 Sm-like protein LSM2 Sorghum bicolor
TI:4558 None
 
A9PD52_POPTR
EnsemblPlants»
0.0
POPTR_003G014900 POPTR_004G219000 Sm-like protein LSM2 Populus trichocarpa
TI:3694 None
 
B6UER1_MAIZE
EnsemblPlants»
0.0
100276999 Sm-like protein LSM2 Zea mays
TI:4577 None
 
B7QF41_IXOSC
EnsemblMetazoa»
0.0
8040318 U6 snRNA-associated Sm-like protein LSm2 Ixodes scapularis
TI:6945 None
 
C6SWL3_SOYBN
EnsemblPlants»
0.0
100305778 Sm-like protein LSM2 Glycine max
TI:3847 None
 
G3R6X6_GORGO
Ensembl»
0.0
LSM2 U6 snRNA-associated Sm-like protein LSm2 Gorilla gorilla
TI:9593 None
 
G7MRK5_MACMU
Ensembl»
0.0
LSM2 U6 snRNA-associated Sm-like protein LSm2 Macaca mulatta
TI:9544 None
 
I1I1J6_BRADI
EnsemblPlants»
0.0
100843890 Sm-like protein LSM2 Brachypodium distachyon
TI:15368 None
 
LSM2_YEAST
SGD»
7.2
LSM2 U6 snRNA-associated Sm-like protein LSm2
(Small nuclear ribonucleoprotein D homolog SNP3)		 Saccharomyces cerevisiae
TI:4932 None
 
A0A072UD03_MEDTR
EnsemblPlants»
0.0
25499092 Sm-like protein LSM2 Medicago truncatula
TI:3880 None
 
A0A078FRE4_BRANA
EnsemblPlants»
0.0
BnaA08g27430D (rape) hypothetical
protein (BnaA08g27430D protein)		 Brassica napus
TI:3708 None
 
A0A251KV49_MANES
EnsemblPlants»
0.0
MANES_01G210300 MANES_05G073100 Sm-like protein LSM2 Manihot esculenta
TI:3983 None
 
A0A251S4Z0_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr15g0466481 HanXRQr2_Chr15g0674341 Sm-like protein LSM2 Helianthus annuus
TI:4232 None
 
A0A251VLF3_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr01g0002411 HanXRQr2_Chr01g0002751 Sm-like protein LSM2 Helianthus annuus
TI:4232 None
 
D8RPV2_SELML
EnsemblPlants»
0.0
SELMODRAFT_175720 SELMODRAFT_232056 Sm-like protein LSM2 Selaginella moellendorffii
TI:88036 None
 
G7KQV7_MEDTR
EnsemblPlants»
0.0
11442020 Sm-like protein LSM2 Medicago truncatula
TI:3880 None
 
Q0J7Y5_ORYSJ
EnsemblPlants»
0.0
Os08g0154700 Sm-like protein LSM2 Oryza sativa
TI:4530 None
 
Q5BL46_XENTR
Xenbase»
0.0
lsm2 U6 snRNA-associated Sm-like protein LSm2 Xenopus tropicalis
TI:8364 None
 
T1ELS1_HELRO
EnsemblMetazoa»
0.0
20197521 U6 snRNA-associated Sm-like protein LSm2 Helobdella robusta
TI:6412 None
 
A0A022S1H2_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a017110mg Sm-like protein LSM2 Erythranthe guttata
TI:4155 None
 
A0A067G038_CITSI
Ensembl»
0.0
CISIN_1g034490mg Sm-like protein LSM2 Citrus sinensis
TI:2711 None
 
A0A0A0K9T1_CUCSA
EnsemblPlants»
0.0
Csa_7G428250 Sm-like protein LSM2 Cucumis sativus
TI:3659 None
 
A0A0K9NKB7_ZOSMR
EnsemblPlants»
0.0
ZOSMA_89G00080 Sm-like protein LSM2 Zostera marina
TI:29655 None
 
A0A1D8PSP7_CANAL
EnsemblFungi»
0.0
SNP3 U6 snRNA-associated Sm-like protein LSm2 Candida albicans
TI:5476 None
 
A0A1U8A2H0_NELNU
EnsemblBacteria»
0.0
LOC104596411 Sm-like protein LSM2 Nelumbo nucifera
TI:4432 None
 
A0A1Y1HYA1_KLENI
EnsemblPlants»
0.0
KFL_001370130 Sm-like protein LSM2 Klebsormidium nitens
TI:105231 None
 
A0A2A6CF50_PRIPA
EnsemblMetazoa»
0.0
WBGene00112087 tRNA-intron lyase (EC 4.6.1.16) Pristionchus pacificus
TI:54126 None
 
A0A2G2ZWI3_CAPAN
EnsemblPlants»
0.0
T459_08421 U6 snRNA-associated Sm-like protein LSm2 Capsicum annuum
TI:4072 None
 
A0A2R6XUW0_MARPO
EnsemblPlants»
0.0
MARPO_0002s0343 Sm-like protein LSM2 Marchantia polymorpha
TI:3197 None
 
A0A337SAY0_FELCA
Ensembl»
0.0
LSM2 U6 snRNA-associated Sm-like protein LSm2 Felis catus
TI:9685 None
 
A0A804K3D3_MUSAM
EnsemblPlants»
0.0
GSMUA_339560.1 Sm-like protein LSM2 Musa acuminata
TI:4641 None
 
A0A804L770_MUSAM
EnsemblPlants»
0.0
GSMUA_12210.1 Sm-like protein LSM2 Musa acuminata
TI:4641 None
 
A0CX56_PARTE
EnsemblProtists»
0.0
GSPATT00001577001 Chromosome undetermined scaffold_3,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A0DPY0_PARTE
EnsemblProtists»
0.0
GSPATT00002496001 Chromosome undetermined scaffold_6,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A2FH88_TRIV3
VEuPathDB»
0.0
TVAG_123170 Sm protein Trichomonas vaginalis
TI:5722 None
 
A5A8V8_PIG
Ensembl»
0.0
LSM2 U6 snRNA-associated Sm-like protein LSm2 Sus scrofa
TI:9823 None
 
A6KTP7_RAT
RGD»
3.5
Lsm2 LSM2 homolog, U6 small nuclear RNA and mRNA degradation
associated (LSM2 homolog, U6 small nuclear RNA associated [S. cerevisiae])		 Rattus norvegicus
TI:10116 None
 
A7E8T0_SCLS1
EnsemblFungi»
0.0
SS1G_01708 U6 snRNA-associated Sm-like protein LSm2 Sclerotinia sclerotiorum
TI:5180 None
 
A7SNR1_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g172574 U6 snRNA-associated Sm-like protein LSm2 Nematostella vectensis
TI:45351 None
 
A8IIA2_CHLRE
EnsemblPlants»
0.0
CHLRE_10g441950v5 Sm-like protein LSM2 Chlamydomonas reinhardtii
TI:3055 None
 
A9TVK1_PHYPA
EnsemblPlants»
0.0
PHYPA_002950 Sm-like protein LSM2 Physcomitrium patens
TI:3218 None
 
A9UZG8_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_32429 U6 snRNA-associated Sm-like protein LSm2 Monosiga brevicollis
TI:81824 None
 
B3RNH8_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_53171 U6 snRNA-associated Sm-like protein LSm2 Trichoplax adhaerens
TI:10228 None
 
B6K2J8_SCHJY
EnsemblFungi»
0.0
SJAG_02469 U6 snRNA-associated Sm-like protein LSm2 Schizosaccharomyces japonicus
TI:4897 None
 
B6UI47_MAIZE
EnsemblPlants»
0.0
100286339 Sm-like protein LSM2 Zea mays
TI:4577 None
 
B8BUU1_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_32314 U6 snRNA-associated Sm-like protein LSm2 Thalassiosira pseudonana
TI:35128 None
 
C5YGY2_SORBI
EnsemblPlants»
0.0
SORBI_3007G043600 Sm-like protein LSM2 Sorghum bicolor
TI:4558 None
 
C8VBS9_EMENI
EnsemblFungi»
0.0
ANIA_10963 U6 snRNA-associated Sm-like protein LSm2 Emericella nidulans
TI:162425 None
 
D6WBR3_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_00255 U6 snRNA-associated Sm-like protein LSm2 Tribolium castaneum
TI:7070 None
 
E3L0P0_PUCGT
EnsemblFungi»
0.0
PGTG_15942 U6 snRNA-associated Sm-like protein LSm2 Puccinia graminis
TI:5297 None
 
E9G8L5_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_209723 U6 snRNA-associated Sm-like protein LSm2 Daphnia pulex
TI:6669 None
 
F1A5M8_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_85411 U6 snRNA-associated Sm-like protein LSm2 Dictyostelium purpureum
TI:5786 None
 
F4P038_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_10632 U6 snRNA-associated Sm-like protein LSm2 Batrachochytrium dendrobatidis
TI:109871 None
 
F6HQ57_VITVI
EnsemblPlants»
0.0
VIT_07s0104g00560 Sm-like protein LSM2 Vitis vinifera
TI:29760 None
 
H2XSZ1_CIOIN
Ensembl»
0.0
U6 snRNA-associated Sm-like protein LSm2 Ciona intestinalis
TI:7719 None
 
H3G5B7_PHYRM
EnsemblProtists»
0.0
U6 snRNA-associated Sm-like protein LSm2 Phytophthora ramorum
TI:164328 None
 
K3YL50_SETIT
EnsemblPlants»
0.0
Sm domain-containing protein Setaria italica
TI:4555 None
 
LSM2_DICDI
dictyBase»
1.5
lsm2 Probable U6 snRNA-associated
Sm-like protein LSm2		 Dictyostelium discoideum
TI:44689 None
 
LSM2_SCHPO
PomBase»
4.3
lsm2 U6 snRNA-associated Sm-like protein LSm2 Schizosaccharomyces pombe
TI:4896 None
 
M4EP09_BRACM
EnsemblPlants»
0.0
BRAA08T35636Z Sm-like protein LSM2 Brassica campestris
TI:3711 None
 
M5X346_PRUPE
EnsemblPlants»
0.0
PRUPE_4G147700 Sm-like protein LSM2 Prunus persica
TI:3760 None
 
P92022_CAEEL
WormBase»
1.0
gut-2 U6 snRNA-associated Sm-like protein LSm2 Caenorhabditis elegans
TI:6239 None
 
Q4WZZ7_ASPFU
EnsemblFungi»
0.0
AFUA_2G15210 U6 snRNA-associated Sm-like protein LSm2 Aspergillus fumigatus
TI:746128 None
 
Q52KE0_XENLA
Xenbase»
0.0
lsm2.L U6 snRNA-associated Sm-like protein LSm2 Xenopus laevis
TI:8355 None
 
Q5KKU9_CRYNJ
EnsemblFungi»
0.0
CNC01770 U6 snRNA-associated Sm-like protein LSm2 Cryptococcus neoformans
TI:5207 None
 
Q6C2F0_YARLI
EnsemblFungi»
0.0
YALI0_F08459g U6 snRNA-associated Sm-like protein LSm2 Yarrowia lipolytica
TI:4952 None
 
Q753Z0_ASHGO
EnsemblFungi»
0.0
AGOS_AFR182C U6 snRNA-associated Sm-like protein LSm2 Ashbya gossypii
TI:33169 None
 
Q7PQ03_ANOGA
EnsemblMetazoa»
0.0
1274814 U6 snRNA-associated Sm-like protein LSm2 Anopheles gambiae
TI:7165 None
 
Q8I3Q7_PLAF7
EnsemblProtists»
0.0
PF3D7_0520300 U6 snRNA-associated Sm-like protein LSm2 Plasmodium falciparum
TI:5833 None
 
Q9VTW6_DROME
FlyBase»
3.5
Dmel\CG10418 U6 snRNA-associated Sm-like protein LSm2 Drosophila melanogaster
TI:7227 None
 
V5IQ99_NEUCR
EnsemblFungi»
0.0
NCU07382 U6 snRNA-associated Sm-like protein LSm2 Neurospora crassa
TI:5141 None
 
W1PQS6_AMBTC
EnsemblPlants»
0.0
AMTR_s00025p00112530 Sm-like protein LSM2 Amborella trichopoda
TI:13333 None
 
W5HPH0_WHEAT
EnsemblPlants»
0.0
CFC21_048653 Sm-like protein LSM2 Triticum aestivum
TI:4565 None
 
W5MD35_LEPOC
Ensembl»
0.0
U6 snRNA-associated Sm-like protein LSm2 Lepisosteus oculatus
TI:7918 None
 
A0A0G2K375_RAT
RGD»
1.0
AC126899.1 Sm domain-containing protein Rattus norvegicus
TI:10116 None
   
A0A1D5R225_MACMU
Ensembl»
0.0
U6 snRNA-associated Sm-like protein LSm2 Macaca mulatta
TI:9544 None
   
A0A1S3X9W8_TOBAC
EnsemblFungi»
0.0
LOC107762847 Sm-like protein LSM2 Nicotiana tabacum
TI:4097 None
   
A0A1S3XWB6_TOBAC
EnsemblFungi»
0.0
LOC107769305 Sm-like protein LSM2 Nicotiana tabacum
TI:4097 None
   
A0A1S4AAJ2_TOBAC
EnsemblFungi»
0.0
LOC107795504 Sm-like protein LSM2 Nicotiana tabacum
TI:4097 None
   
A0A1S4B6Y6_TOBAC
EnsemblFungi»
0.0
LOC107805127 Sm-like protein LSM2 Nicotiana tabacum
TI:4097 None
   
A0A1U8BN09_NELNU
EnsemblBacteria»
0.0
LOC104612860 Sm-like protein LSM2 Nelumbo nucifera
TI:4432 None
   
A0A1U8NN29_GOSHI
Ensembl»
0.0
LOC107949227 Sm-like protein LSM2 Gossypium hirsutum
TI:3635 None
   
A0A2I4G541_JUGRE
EnsemblPlants»
0.0
LOC109004791 Sm-like protein LSM2 Juglans regia
TI:51240 None
   
A0A2I4GU76_JUGRE
EnsemblPlants»
0.0
LOC109010925 Sm-like protein LSM2 Juglans regia
TI:51240 None
   
A0A3B3IAS1_ORYLA
Ensembl»
0.0
lsm2 U6 snRNA-associated Sm-like protein LSm2 Oryzias latipes
TI:8090 None
   
A0A3Q7FID0_SOLLC
EnsemblPlants»
0.0
Sm domain-containing protein Solanum lycopersicum
TI:4081 None
   
A0A3Q7H5E5_SOLLC
EnsemblPlants»
0.0
101250608 Sm-like protein LSM2 Solanum lycopersicum
TI:4081 None
   
A0A3Q7I6B1_SOLLC
EnsemblPlants»
0.0
104649355 Sm-like protein LSM2 Solanum lycopersicum
TI:4081 None
   
A0A7M7PM85_STRPU
EnsemblMetazoa»
0.0
U6 snRNA-associated Sm-like protein LSm2 Strongylocentrotus purpuratus
TI:7668 None
   
A0A8I3NE02_CANLF
Ensembl»
0.0
LSM2 U6 snRNA-associated Sm-like protein LSm2 Canis lupus
TI:9612 None
   
A0A8I3PWT6_CANLF
Ensembl»
0.0
U6 snRNA-associated Sm-like protein LSm2 Canis lupus
TI:9612 None
   
A0A8I6AII7_RAT
RGD»
0.0
ENSRNOG00000066763 Uncharacterized protein Rattus norvegicus
TI:10116 None 		     
A0A9J7MZX5_BRAFL
CTD»
0.0
LOC118421550 U6 snRNA-associated Sm-like protein LSm2 Branchiostoma floridae
TI:7739 None
   
F6UIV8_ORNAN
Ensembl»
0.0
U6 snRNA-associated Sm-like protein LSm2 Ornithorhynchus anatinus
TI:9258 None
   
F7BP16_HORSE
Ensembl»
0.0
LSM2 U6 snRNA-associated Sm-like protein LSm2 Equus caballus
TI:9796 None
   
F7BWI8_MONDO
Ensembl»
0.0
LSM2 U6 snRNA-associated Sm-like protein LSm2 Monodelphis domestica
TI:13616 None
   
H9GP66_ANOCA
Ensembl»
0.0
LSM2 U6 snRNA-associated Sm-like protein LSm2 Anolis carolinensis
TI:28377 None
   
M0ZWY5_SOLTU
EnsemblPlants»
0.0
102601306 Sm-like protein LSM2 Solanum tuberosum
TI:4113 None
   
M1BRY0_SOLTU
EnsemblPlants»
0.0
102600939 Sm-like protein LSM2 Solanum tuberosum
TI:4113 None