Collated Gene Ontology terms

Biological process: RNA binding(2013, 2014, 2015, 2023, 2024) poly(U) RNA binding(2017, 2024) U2 snRNA binding(2023, 2024) small GTPase binding(2014, 2024) protein kinase binding(2011) tRNA-intron endonuclease activity(2024) U6 snRNA binding(2003) RNA folding chaperone(2023)

Molecular function: mRNA splicing, via spliceosome2006, 2010, 2011, 2015, 2016, 2017, 2018, 2019, 2020, 2022, 2024 mRNA processing2024 RNA splicing2024 deadenylation-dependent decapping of nuclear-transcribed mRNA2015, 2017, 2024 tRNA processing2015, 2024 rRNA processing2015, 2024 spliceosomal tri-snRNP complex assembly2019, 2024 mRNA catabolic process2019, 2024 translation2021 telomerase holoenzyme complex assembly2018
tRNA splicing, via endonucleolytic cleavage and ligation2024 regulation of alternative mRNA splicing, via spliceosome2006 RNA folding2024

Cellular component: U4/U6 x U5 tri-snRNP complex2006, 2013, 2016, 2018, 2019, 2020, 2022, 2024 nucleus2006, 2015, 2016, 2017, 2018, 2022, 2024 U6 snRNP2006, 2015, 2016, 2023, 2024 Lsm1-7-Pat1 complex2015, 2017, 2023, 2024 spliceosomal complex2006, 2016, 2024 P-body2015, 2017, 2024 catalytic step 2 spliceosome2010, 2011, 2017, 2024 precatalytic spliceosome2010, 2017, 2024 Lsm2-8 complex2017, 2018, 2023, 2024 cytoplasm2018, 2019, 2024
protein-containing complex2024 nucleolus2005, 2006, 2015, 2024 sno(s)RNA-containing ribonucleoprotein complex2019, 2024 U5 snRNP2023, 2024 U2-type precatalytic spliceosome2018, 2024 nucleoplasm2013, 2023, 2024 telomerase holoenzyme complex2022 small nuclear ribonucleoprotein complex2006 membrane2024 cytosol2013 U4/U6 snRNP2016 U2 snRNP2023

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 1/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 34/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A0G2K375_RAT
RGD»
1.0
AC126899.1 Sm domain-containing protein Rattus norvegicus
TI:10116 None
   
Q9VTW6_DROME
FlyBase»
3.5
Dmel\CG10418 U6 snRNA-associated Sm-like protein LSm2 Drosophila melanogaster
TI:7227 None
 
A0A8I6AII7_RAT
RGD»
0.0
ENSRNOG00000066763 Uncharacterized protein Rattus norvegicus
TI:10116 None 		     
LSM2_ARATH
TAIR»
2.2
LSM2 Sm-like protein LSM2 (AtLSM2)
(U6 snRNA-associated Sm-like protein LSM2)		 Arabidopsis thaliana
TI:3702 None
 
LSM2_HUMAN
Ensembl»
6.9
LSM2 U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (Small nuclear
ribonuclear protein D homolog) (snRNP core Sm-like protein Sm-x5)		 Homo sapiens
TI:9606 None
 
LSM2_YEAST
SGD»
7.2
LSM2 U6 snRNA-associated Sm-like protein LSm2
(Small nuclear ribonucleoprotein D homolog SNP3)		 Saccharomyces cerevisiae
TI:4932 None
 
A6KTP7_RAT
RGD»
3.5
Lsm2 LSM2 homolog, U6 small nuclear RNA and mRNA degradation
associated (LSM2 homolog, U6 small nuclear RNA associated [S. cerevisiae])		 Rattus norvegicus
TI:10116 None
 
LSM2_MOUSE
Ensembl»
2.3
Lsm2 U6 snRNA-associated Sm-like protein LSm2 (Protein
G7b) (snRNP core Sm-like protein Sm-x5)		 Mus musculus
TI:10090 None
 
P92022_CAEEL
WormBase»
1.0
gut-2 U6 snRNA-associated Sm-like protein LSm2 Caenorhabditis elegans
TI:6239 None
 
LSM2_DICDI
dictyBase»
1.5
lsm2 Probable U6 snRNA-associated
Sm-like protein LSm2		 Dictyostelium discoideum
TI:44689 None
 
LSM2_SCHPO
PomBase»
4.3
lsm2 U6 snRNA-associated Sm-like protein LSm2 Schizosaccharomyces pombe
TI:4896 None
 
Q5RKP8_DANRE
ZFIN»
1.0
lsm2 U6 snRNA-associated Sm-like protein LSm2 Danio rerio
TI:7955 None