Collated Gene Ontology terms

Biological process: GTPase activity(2010, 2017, 2025) signal recognition particle binding(2008, 2009, 2013, 2014, 2017, 2025) GTP binding(2004, 2009, 2025) nucleotide binding(2025) hydrolase activity(2025) RNA binding(2004, 2014) protein homodimerization activity(2018) nucleic acid binding(2025) metal ion binding(2025) identical protein binding(2025)
RNA-DNA hybrid ribonuclease activity2025

Molecular function: SRP-dependent cotranslational protein targeting to membrane2004, 2022, 2025 protein targeting to ER2008, 2013, 2017, 2025 protein targeting2024, 2025 intracellular protein transport2009, 2025 protein targeting to membrane2025 cell division2025 protein transport2025 bacterial-type flagellum organization2025 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition2024, 2025 cotranslational protein targeting to membrane2003, 2014
thylakoid membrane organization2008 stringent response2022 regulation of protein secretion2004 protein import into chloroplast thylakoid membrane2009 photosynthetic electron transport in photosystem II2009 neutrophil differentiation2024 axonogenesis2004

Cellular component: endoplasmic reticulum membrane2004, 2008, 2009, 2013, 2018, 2023, 2025 membrane2013, 2023, 2024, 2025 signal recognition particle receptor complex2005, 2009, 2014, 2025 cytoplasm2025 plasma membrane2010, 2017, 2023, 2025 endomembrane system2014, 2025 chloroplast2007, 2018, 2021, 2025 endoplasmic reticulum2017, 2018, 2021, 2025 cytosol2009, 2010, 2019 nuclear envelope2017
protein-containing complex2025 peptidoglycan-based cell wall2012 nucleus2009 extracellular exosome2013 cytoplasmic side of plasma membrane2022 chloroplast thylakoid membrane2025 chloroplast thylakoid2003 chloroplast stroma2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 4/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 39/39 
Archea: 8/8 
Bacteria: 35/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
FTSY_ECOLI
EnsemblBacteria»
4.7
ftsY Signal recognition particle receptor
FtsY (SRP receptor) (EC 3.6.5.4)		 Escherichia coli
TI:562 None
 
SRPRA_DROME
FlyBase»
4.3
SrpRalpha Signal recognition particle receptor subunit alpha homolog
(DP-alpha) (Docking protein alpha) (SR-alpha) (GTP-binding protein)		 Drosophila melanogaster
TI:7227 None
 
CFTSY_ARATH
TAIR»
3.9
CPFTSY Cell division protein FtsY homolog, chloroplastic (Chloroplast SRP receptor
homolog, alpha subunit CpFtsY) (Fused signal recognition particle receptor)		 Arabidopsis thaliana
TI:3702 None
 
SRPR_YEAST
SGD»
3.7
SRP101 Signal recognition particle receptor subunit alpha
homolog (SR-alpha) (Docking protein alpha) (DP-alpha)		 Saccharomyces cerevisiae
TI:4932 None
 
SRPRA_HUMAN
Ensembl»
3.5
SRPRA Signal recognition particle receptor subunit
alpha (SR-alpha) (Docking protein alpha) (DP-alpha)		 Homo sapiens
TI:9606 None
 
SRPR_SCHPO
PomBase»
3.1
srp101 Signal recognition particle receptor subunit alpha
homolog (SR-alpha) (Docking protein alpha) (DP-alpha)		 Schizosaccharomyces pombe
TI:4896 None
 
SRPRA_DICDI
dictyBase»
2.5
srpra Signal recognition particle receptor subunit alpha (SR-alpha)
(Signal recognition particle receptor) (Docking protein alpha) (DP-alpha)		 Dictyostelium discoideum
TI:44689 None
 
E7EZW6_DANRE
ZFIN»
2.3
srpra SRP receptor subunit alpha (Signal
recognition particle receptor subunit alpha)		 Danio rerio
TI:7955 None
 
SRPRA_MOUSE
Ensembl»
2.1
Srpra Signal recognition particle receptor subunit
alpha (SR-alpha) (Docking protein alpha) (DP-alpha)		 Mus musculus
TI:10090 None
 
G4RYA5_CAEEL
WormBase»
1.5
CELE_F38A1.8 F38A1.8 SRP54-type proteins
GTP-binding domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
Q9M0A0_ARATH
TAIR»
1.5
At4g30600 AT4g30600/F17I23_60 (Signal recognition particle receptor alpha subunit
family protein) (Signal recognition particle receptor-like protein)		 Arabidopsis thaliana
TI:3702 None
 
A0A8V0ZUZ6_CHICK
Ensembl»
0.0
SRPRA SRP receptor alpha subunit Gallus gallus
TI:9031 None
   
Q3KRC3_RAT
RGD»
0.0
Srpra Signal recognition particle receptor
subunit alpha (Docking protein alpha)		 Rattus norvegicus
TI:10116 None