Collated Gene Ontology terms

Biological process: translation initiation factor activity(2025) RNA binding(2025)

Molecular function: translational initiation2025 translation2025 cytoplasmic translational initiation2011

Cellular component: nucleus2009, 2012, 2018, 2021, 2025 nucleoplasm2024, 2025 cytosol2009, 2025 cytoplasm2025

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 10/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A1S4H382_ANOGA
EnsemblMetazoa»
0.0
Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Anopheles gambiae
TI:7165 None
 
A0A3B6IX76_WHEAT
EnsemblPlants»
0.0
S1-like domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6IXD4_WHEAT
EnsemblPlants»
0.0
S1-like domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6LXY6_WHEAT
EnsemblPlants»
0.0
S1-like domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6N2P3_WHEAT
EnsemblPlants»
0.0
S1-like domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3Q7GBJ2_SOLLC
EnsemblPlants»
0.0
Uncharacterized protein Solanum lycopersicum
TI:4081 None 		     
A0A5F8GM63_MONDO
Ensembl»
0.0
Uncharacterized protein Monodelphis domestica
TI:13616 None 		     
A0A6I8N6F4_ORNAN
Ensembl»
0.0
Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Ornithorhynchus anatinus
TI:9258 None
   
A0A6I8PDE8_ORNAN
Ensembl»
0.0
Uncharacterized protein Ornithorhynchus anatinus
TI:9258 None 		     
A0A7I4F764_PHYPA
EnsemblPlants»
0.0
S1-like domain-containing protein Physcomitrium patens
TI:3218 None
 
A0A7M7RFV1_STRPU
EnsemblMetazoa»
0.0
Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Strongylocentrotus purpuratus
TI:7668 None
   
F7AXG2_MONDO
Ensembl»
0.0
Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Monodelphis domestica
TI:13616 None
   
H3GIY3_PHYRM
EnsemblProtists»
0.0
S1-like domain-containing protein Phytophthora ramorum
TI:164328 None
 
K4ADH1_SETIT
EnsemblPlants»
0.0
S1-like domain-containing protein Setaria italica
TI:4555 None
 
M1BUE6_SOLTU
EnsemblPlants»
0.0
RNA binding / translation initiation factor Solanum tuberosum
TI:4113 None
   
W5M1C2_LEPOC
Ensembl»
0.0
Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Lepisosteus oculatus
TI:7918 None
 
T1G130_HELRO
EnsemblMetazoa»
0.0
20214778 Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Helobdella robusta
TI:6412 None
 
A4D9H9_ASPFU
TubercuList»
0.0
AFUA_5G11985 Eukaryotic translation initation
factor eIF1a-like protein, putative		 Aspergillus fumigatus
TI:746128 None
 
U5D585_AMBTC
euHCVdb»
0.0
AMTR_s00059p00149620 S1-like domain-containing protein Amborella trichopoda
TI:13333 None
 
W1P8G4_AMBTC
neXtProt»
0.0
AMTR_s00077p00119490 S1-like domain-containing protein Amborella trichopoda
TI:13333 None
 
Q5BH75_EMENI
TubercuList»
0.0
ANIA_00105 Eukaryotic translation initation factor
eIF1a-like protein, putative (AFU_orthologue AFUA_5G11985)		 Emericella nidulans
TI:162425 None
 
F4II37_ARATH
TAIR»
0.0
At2g40780 Nucleic acid-binding, OB-fold-like protein Arabidopsis thaliana
TI:3702 None
 
F4NXX2_BATDJ
euHCVdb»
0.0
BATDEDRAFT_23639 S1-like domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
A0A397ZQ92_BRACM
EnsemblPlants»
0.0
BRAA04T18571Z BRAPAZ1V2_A04P32330.2 BRARA_D02487 S1-like domain-containing protein Brassica campestris
TI:3711 None
 
A0A078HTC9_BRANA
euHCVdb»
0.0
BnaC01g19880D BnaC01g19880D protein Brassica napus
TI:3708 None
 
A0A078F7A0_BRANA
euHCVdb»
0.0
BnaC03g62960D (rape) hypothetical
protein (BnaC03g62960D protein)		 Brassica napus
TI:3708 None
 
A0A078F5M0_BRANA
euHCVdb»
0.0
BnaC04g47390D BnaC04g47390D protein Brassica napus
TI:3708 None
 
EIF1A_CAEBR
WormBase»
0.0
CBG09545 Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Caenorhabditis briggsae
TI:6238 None
 
EIF1A_DROME
FlyBase»
0.0
CG31957 Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Drosophila melanogaster
TI:7227 None
 
A8J7J8_CHLRE
neXtProt»
0.0
CHLRE_03g155800v5 S1-like domain-containing protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A067FN38_CITSI
euHCVdb»
0.0
CISIN_1g030718mg S1-like domain-containing protein Citrus sinensis
TI:2711 None
 
A0A0A0KM30_CUCSA
neXtProt»
0.0
Csa_5G218810 S1-like domain-containing protein Cucumis sativus
TI:3659 None
 
Q54DL9_DICDI
dictyBase»
0.0
DDB_G0292138 S1-like domain-containing protein Dictyostelium discoideum
TI:44689 None
 
F1A5A5_DICPU
TubercuList»
0.0
DICPUDRAFT_159921 S1-like domain-containing protein Dictyostelium purpureum
TI:5786 None
 
A0A8I3S0Q1_CANLF
Ensembl»
0.0
EIF1AD Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Canis lupus
TI:9612 None
   
A0A9L0S124_HORSE
Ensembl»
0.0
EIF1AD Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Equus caballus
TI:9796 None
   
A0ABI8AIT6_FELCA
Ensembl»
0.0
EIF1AD Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Felis catus
TI:9685 None
   
EIF1A_BOVIN
CTD»
0.0
EIF1AD Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Bos taurus
TI:9913 None
 
EIF1A_HUMAN
Ensembl»
0.0
EIF1AD Probable RNA-binding protein EIF1AD (Eukaryotic translation
initiation factor 1A domain-containing protein) (Haponin)		 Homo sapiens
TI:9606 None
 
F1RU32_PIG
Ensembl»
0.0
EIF1AD Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Sus scrofa
TI:9823 None
 
F6T7W0_MACMU
Ensembl»
0.0
EIF1AD Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Macaca mulatta
TI:9544 None
 
F7G2D0_MONDO
Ensembl»
0.0
EIF1AD Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Monodelphis domestica
TI:13616 None
   
G3R7Z8_GORGO
Ensembl»
0.0
EIF1AD Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Gorilla gorilla
TI:9593 None
 
H2M116_ORYLA
Ensembl»
0.0
EIF1AD Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Oryzias latipes
TI:8090 None
   
H2REF5_PANTR
Ensembl»
0.0
EIF1AD Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Pan troglodytes
TI:9598 None
 
E9HGJ3_DAPPU
euHCVdb»
0.0
EOG090X0KPP Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Daphnia pulex
TI:6669 None
 
EIF1A_MOUSE
Ensembl»
0.0
Eif1ad Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Mus musculus
TI:10090 None
 
EIF1A_RAT
RGD»
0.0
Eif1ad Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Rattus norvegicus
TI:10116 None
 
D2A2U4_TRICA
euHCVdb»
0.0
GLEAN_08520 Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Tribolium castaneum
TI:7070 None
 
A0A804LAI6_MUSAM
EnsemblPlants»
0.0
GSMUA_03210.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0A9K3INQ1_HELAN
neXtProt»
0.0
HanXRQr2_Chr07g0314061 Translation initiation factor 1A (eIF-1A),
RNA-binding domain, S1, IF1 type		 Helianthus annuus
TI:4232 None
 
A0A9K3IPA5_HELAN
euHCVdb»
0.0
HanXRQr2_Chr07g0314071 Uncharacterized protein Helianthus annuus
TI:4232 None 		 
 
A0A251UEK2_HELAN
euHCVdb»
0.0
HannXRQ_Chr07g0204961 Putative nucleic acid-binding, OB-fold protein Helianthus annuus
TI:4232 None
 
A0A251SLU3_HELAN
neXtProt»
0.0
HannXRQ_Chr14g0460541 HanXRQr2_Chr14g0667901 Putative nucleic acid-binding, OB-fold-like protein (Translation initiation
factor 1A (eIF-1A), RNA-binding domain, S1, IF1 type)		 Helianthus annuus
TI:4232 None
 
B7P9A2_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW002071 Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Ixodes scapularis
TI:6945 None
 
A0A7U2I245_PHANO
TubercuList»
0.0
JI435_164960 S1-like domain-containing protein Phaeosphaeria nodorum
TI:13684 None
 
A0A1Y1HVR1_KLENI
neXtProt»
0.0
KFL_001210080 Nucleic acid-binding OB-fold-like protein Klebsormidium nitens
TI:105231 None
 
F6WIJ0_CIOIN
Ensembl»
0.0
LOC100184340 Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Ciona intestinalis
TI:7719 None
 
B6TAS4_MAIZE
EnsemblPlants»
0.0
LOC100282726 Nucleic acid-binding OB-fold-like
protein (RNA binding protein)		 Zea mays
TI:4577 None
 
I1KB64_SOYBN
EnsemblPlants»
0.0
LOC100306612 S1-like domain-containing protein Glycine max
TI:3847 None
 
I1HAL2_BRADI
EnsemblPlants»
0.0
LOC100828332 S1-like domain-containing protein Brachypodium distachyon
TI:15368 None
 
A0A3Q7GMH8_SOLLC
EnsemblPlants»
0.0
LOC101267408 S1-like domain-containing protein Solanum lycopersicum
TI:4081 None
   
K3YW77_SETIT
EnsemblPlants»
0.0
LOC101764763 S1-like domain-containing protein Setaria italica
TI:4555 None
 
M1AU73_SOLTU
EnsemblPlants»
0.0
LOC102585241 RNA binding protein Solanum tuberosum
TI:4113 None
   
A0A1U7ZVI9_NELNU
neXtProt»
0.0
LOC104594460 Probable RNA-binding protein EIF1AD Nelumbo nucifera
TI:4432 None
   
A0A1S3YJD7_TOBAC
euHCVdb»
0.0
LOC107776914 Probable RNA-binding protein
EIF1AD (Uncharacterized protein LOC107776914)		 Nicotiana tabacum
TI:4097 None
   
A0A1S4AZU1_TOBAC
euHCVdb»
0.0
LOC107802982 Probable RNA-binding protein
EIF1AD (Uncharacterized protein LOC107802982)		 Nicotiana tabacum
TI:4097 None
   
A0A1U8ILJ6_GOSHI
euHCVdb»
0.0
LOC107896569 Probable RNA-binding protein EIF1AD Gossypium hirsutum
TI:3635 None
   
A0A1U8KIY6_GOSHI
euHCVdb»
0.0
LOC107916260 Probable RNA-binding protein EIF1AD Gossypium hirsutum
TI:3635 None
   
A0A2I4G9E2_JUGRE
euHCVdb»
0.0
LOC109005875 Probable RNA-binding protein EIF1AD Juglans regia
TI:51240 None
   
A0A2I4H6Q2_JUGRE
euHCVdb»
0.0
LOC109013991 Probable RNA-binding protein EIF1AD Juglans regia
TI:51240 None
   
A0A9R0IPU1_SPIOL
neXtProt»
0.0
LOC110792560 Probable RNA-binding protein EIF1AD Spinacia oleracea
TI:3562 None
   
A0A9J7LKJ2_BRAFL
euHCVdb»
0.0
LOC118421353 Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Branchiostoma floridae
TI:7739 None
   
A0A3B6C0B7_WHEAT
EnsemblPlants»
0.0
LOC123043712 S1-like domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6I294_WHEAT
EnsemblPlants»
0.0
LOC123082679 S1-like domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6U1I2_WHEAT
EnsemblPlants»
0.0
LOC123099268 S1-like domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6KSN4_WHEAT
EnsemblPlants»
0.0
LOC123105749 S1-like domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6KT65_WHEAT
EnsemblPlants»
0.0
LOC123108604 S1-like domain-containing protein Triticum aestivum
TI:4565 None
   
F2EBY6_HORVV
EnsemblPlants»
0.0
LOC123403505 Predicted protein Hordeum vulgare
TI:4513 None
 
Q8GZX2_ORYSJ
euHCVdb»
0.0
LOC_Os03g02310 Os03g0114200 LOC496359 protein, putative, expressed (Os03g0114200
protein) (cDNA clone:002-134-G09, full insert sequence)		 Oryza sativa
TI:4530 None
 
A0A9R1WGZ6_LACSA
neXtProt»
0.0
LSAT_V11C200097210 S1-like domain-containing protein Lactuca sativa
TI:4236 None
 
A0A9R1VZA8_LACSA
neXtProt»
0.0
LSAT_V11C400157820 S1-like domain-containing protein Lactuca sativa
TI:4236 None
 
A0A9R1VMV8_LACSA
neXtProt»
0.0
LSAT_V11C500266320 S1-like domain-containing protein Lactuca sativa
TI:4236 None
 
A0A2R6XHZ1_MARPO
euHCVdb»
0.0
MARPO_0014s0200 S1-like domain-containing protein Marchantia polymorpha
TI:3197 None
 
A0A022R686_ERYGU
euHCVdb»
0.0
MIMGU_mgv1a015058mg S1-like domain-containing protein Erythranthe guttata
TI:4155 None
 
A0A022QT46_ERYGU
neXtProt»
0.0
MIMGU_mgv1a021159mg S1-like domain-containing protein Erythranthe guttata
TI:4155 None
 
A9VA63_MONBE
neXtProt»
0.0
MONBRDRAFT_38794 S1-like domain-containing protein Monosiga brevicollis
TI:81824 None
 
A0A072V1F7_MEDTR
EnsemblPlants»
0.0
MTR_3g093790 Nucleic acid-binding, OB-fold-like protein Medicago truncatula
TI:3880 None
 
Q1K8F3_NEUCR
TubercuList»
0.0
NCU06553 S1-like domain-containing protein Neurospora crassa
TI:5141 None
 
A7S7U6_NEMVE
neXtProt»
0.0
NEMVEDRAFT_v1g108065 Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Nematostella vectensis
TI:45351 None
 
U5FET9_POPTR
euHCVdb»
0.0
POPTR_019G061200 S1-like domain-containing protein Populus trichocarpa
TI:3694 None
 
M5XKZ2_PRUPE
euHCVdb»
0.0
PRUPE_2G265600 Uncharacterized protein Prunus persica
TI:3760 None
 
D8R6H5_SELML
euHCVdb»
0.0
SELMODRAFT_407703 Uncharacterized protein Selaginella moellendorffii
TI:88036 None 		 
 
C5X127_SORBI
euHCVdb»
0.0
SORBI_3001G533800 S1-like domain-containing protein Sorghum bicolor
TI:4558 None
 
YN98_SCHPO
PomBase»
0.6
SPBC146.08c S1-like domain-containing protein C146.08c Schizosaccharomyces pombe
TI:4896 None
 
A7F8U8_SCLS1
TubercuList»
0.0
SS1G_14029 S1-like domain-containing protein Sclerotinia sclerotiorum
TI:5180 None
 
A0A1U8G199_CAPAN
neXtProt»
0.0
T459_08500 S1-like domain-containing protein Capsicum annuum
TI:4072 None
 
A0A061FZI6_THECC
euHCVdb»
0.0
TCM_045564 OB-fold nucleic acid
binding domain-containing protein		 Theobroma cacao
TI:3641 None
 
B8C5G0_THAPS
euHCVdb»
0.0
THAPSDRAFT_269049 S1-like domain-containing protein Thalassiosira pseudonana
TI:35128 None
 
B3S6G8_TRIAD
CTD»
0.0
TRIADDRAFT_59800 Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Trichoplax adhaerens
TI:10228 None
 
F6H7B2_VITVI
neXtProt»
0.0
VIT_16s0098g01610 S1-like domain-containing protein Vitis vinifera
TI:29760 None
 
A0A2A6CRW8_PRIPA
EnsemblMetazoa»
0.0
WBGene00276076 Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Pristionchus pacificus
TI:54126 None
   
Q6BZS1_YARLI
TubercuList»
0.0
YALI0_F31339g YALI0F31339p Yarrowia lipolytica
TI:4952 None
 
EIF1A_CAEEL
WormBase»
0.0
ZK856.11 Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Caenorhabditis elegans
TI:6239 None
 
A0A0K9NVE5_ZOSMR
euHCVdb»
0.0
ZOSMA_61G00080 Eukaryotic translation initiation
factor 1A domain-containingprotein		 Zostera marina
TI:29655 None
 
EIF1A_CHICK
CTD»
0.0
eif1ad Probable RNA-binding protein EIF1AD (Eukaryotic translation
initiation factor 1A domain-containing protein) (Protein Obelix)		 Gallus gallus
TI:9031 None
 
EIF1A_DANRE
ZFIN»
0.0
eif1ad Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Danio rerio
TI:7955 None
 
EIF1A_XENLA
Xenbase»
0.0
eif1ad Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Xenopus laevis
TI:8355 None
 
EIF1A_XENTR
Xenbase»
0.0
eif1ad Probable RNA-binding protein EIF1AD (Eukaryotic
translation initiation factor 1A domain-containing protein)		 Xenopus tropicalis
TI:8364 None
 
B6K5M0_SCHJY
TubercuList»
0.0
tif1102 Translation initiation factor eIF1A-like protein Schizosaccharomyces japonicus
TI:4897 None