Collated Gene Ontology terms

Biological process: tRNA binding(2024) sulfurtransferase activity(2015, 2023, 2024) nucleotidyltransferase activity(2024) tRNA-specific 2-thiouridylase activity(2022, 2023, 2024) hydrolase activity(2024)

Molecular function: tRNA thio-modification2009, 2015, 2024 tRNA wobble uridine modification2009, 2022, 2024 tRNA wobble position uridine thiolation2013, 2016, 2023, 2024 protein urmylation2013, 2024 tRNA processing2024 lateral root formation2015, 2024 pseudohyphal growth2013, 2024 invasive growth in response to glucose limitation2013, 2024 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 filamentous growth2023
endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021

Cellular component: cytosol2009, 2015, 2017, 2024 cytoplasm2018, 2024 protein-containing complex2009, 2024 cytosolic tRNA wobble base thiouridylase complex2017, 2022, 2024 nucleus2009, 2024

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 3/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 36/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A2DL51_TRIV3
VEuPathDB»
0.0
TVAG_294940 Uncharacterized protein Trichomonas vaginalis
TI:5722 None
 
B9SUD7_RICCO
EnsemblBacteria»
0.0
RCOM_0749470 Uncharacterized protein Ricinus communis
TI:3988 None
 
C4LYA0_ENTH1
EnsemblProtists»
0.0
EHI_166980 Uncharacterized protein Entamoeba histolytica
TI:5759 None
 
D8RRI5_SELML
EnsemblPlants»
0.0
SELMODRAFT_54556 Uncharacterized protein Selaginella moellendorffii
TI:88036 None
 
D8RXE4_SELML
EnsemblPlants»
0.0
SELMODRAFT_54559 Uncharacterized protein Selaginella moellendorffii
TI:88036 None
 
A0A6P9EKZ4_JUGRE
EnsemblPlants»
0.0
LOC118349270 Cytoplasmic tRNA 2-thiolation protein 2-like Juglans regia
TI:51240 None
   
CTU2B_XENLA
Xenbase»
0.0
ctu2-b Cytoplasmic tRNA 2-thiolation protein 2-B Xenopus laevis
TI:8355 None
 
CTU2A_XENLA
Xenbase»
0.0
ctu2-a Cytoplasmic tRNA 2-thiolation protein 2-A Xenopus laevis
TI:8355 None
 
CTU2_CAEBR
WormBase»
0.0
tut-2 Cytoplasmic tRNA 2-thiolation protein 2 (Thiolation
of uridine in tRNA protein 2)		 Caenorhabditis briggsae
TI:6238 None
 
CTU2_CAEEL
WormBase»
2.0
tut-2 Cytoplasmic tRNA 2-thiolation protein 2 (Thiolation
of uridine in tRNA protein 2)		 Caenorhabditis elegans
TI:6239 None
 
CTU2_YEAST
SGD»
5.8
NCS2 Cytoplasmic tRNA 2-thiolation protein 2 (Needs CLA4 to survive
protein 2) (Thiolation of uridine in cytoplasmic tRNA protein 2)		 Saccharomyces cerevisiae
TI:4932 None
 
A0A022PT61_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a005684mg Cytoplasmic tRNA 2-thiolation protein 2 Erythranthe guttata
TI:4155 None
 
A0A061EXW3_THECC
EnsemblPlants»
0.0
TCM_024635 Cytoplasmic tRNA 2-thiolation protein 2 Theobroma cacao
TI:3641 None
 
A0A067DE38_CITSI
Ensembl»
0.0
CISIN_1g0128551mg Cytoplasmic tRNA 2-thiolation protein 2 Citrus sinensis
TI:2711 None
 
A0A067DEI5_CITSI
Ensembl»
0.0
CISIN_1g0128552mg Cytoplasmic tRNA 2-thiolation protein 2 Citrus sinensis
TI:2711 None
 
A0A072U1R0_MEDTR
EnsemblPlants»
0.0
25499016 Cytoplasmic tRNA 2-thiolation protein 2 Medicago truncatula
TI:3880 None
 
A0A0A0LC57_CUCSA
EnsemblPlants»
0.0
Csa_3G816060 Cytoplasmic tRNA 2-thiolation protein 2 Cucumis sativus
TI:3659 None
 
A0A0K9NL86_ZOSMR
EnsemblPlants»
0.0
ZOSMA_86G00120 Cytoplasmic tRNA 2-thiolation protein 2 Zostera marina
TI:29655 None
 
A0A1S4BZD6_TOBAC
EnsemblFungi»
0.0
LOC107813504 Cytoplasmic tRNA 2-thiolation protein 2 Nicotiana tabacum
TI:4097 None
   
A0A1S4DG59_TOBAC
EnsemblFungi»
0.0
LOC107829529 Cytoplasmic tRNA 2-thiolation protein 2 Nicotiana tabacum
TI:4097 None
   
A0A1U7Z3K9_NELNU
EnsemblBacteria»
0.0
LOC104589953 Cytoplasmic tRNA 2-thiolation protein 2 Nelumbo nucifera
TI:4432 None
   
A0A1U8K234_GOSHI
Ensembl»
0.0
LOC107912772 Cytoplasmic tRNA 2-thiolation protein 2 Gossypium hirsutum
TI:3635 None
   
A0A1U8K2R1_GOSHI
Ensembl»
0.0
LOC107912900 Cytoplasmic tRNA 2-thiolation protein 2 Gossypium hirsutum
TI:3635 None
   
A0A1Y1HUL3_KLENI
EnsemblPlants»
0.0
KFL_000830040 Cytoplasmic tRNA 2-thiolation protein 2 Klebsormidium nitens
TI:105231 None
 
A0A251TUA3_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr09g0252561 HanXRQr2_Chr06g0257201 Cytoplasmic tRNA 2-thiolation protein 2 Helianthus annuus
TI:4232 None
 
A0A287AEA8_PIG
Ensembl»
0.0
CTU2 Cytoplasmic tRNA 2-thiolation protein 2 Sus scrofa
TI:9823 None
 
A0A2A6CZT8_PRIPA
EnsemblMetazoa»
0.0
WBGene00116841 Cytoplasmic tRNA 2-thiolation protein 2 Pristionchus pacificus
TI:54126 None
 
A0A2C9V764_MANES
EnsemblPlants»
0.0
MANES_09G022000 Cytoplasmic tRNA 2-thiolation protein 2 Manihot esculenta
TI:3983 None
 
A0A2C9VDP3_MANES
EnsemblPlants»
0.0
MANES_08G050400 Cytoplasmic tRNA 2-thiolation protein 2 Manihot esculenta
TI:3983 None
 
A0A2G2YNS4_CAPAN
EnsemblPlants»
0.0
T459_26494 Cytoplasmic tRNA 2-thiolation protein 2 Capsicum annuum
TI:4072 None
 
A0A2I4DDE2_JUGRE
EnsemblPlants»
0.0
LOC108979044 Cytoplasmic tRNA 2-thiolation protein 2 Juglans regia
TI:51240 None
 
A0A2K1JIE0_PHYPA
EnsemblPlants»
0.0
PHYPA_018724 Cytoplasmic tRNA 2-thiolation protein 2 Physcomitrium patens
TI:3218 None
 
A0A2K1ZX35_POPTR
EnsemblPlants»
0.0
POPTR_006G051300 Cytoplasmic tRNA 2-thiolation protein 2 Populus trichocarpa
TI:3694 None
 
A0A2K3E7L8_CHLRE
EnsemblPlants»
0.0
CHLRE_01g043500v5 Cytoplasmic tRNA 2-thiolation protein 2 Chlamydomonas reinhardtii
TI:3055 None
 
A0A2R6W3G7_MARPO
EnsemblPlants»
0.0
MARPO_0165s0023 Cytoplasmic tRNA 2-thiolation protein 2 Marchantia polymorpha
TI:3197 None
 
A0A3B3HX53_ORYLA
Ensembl»
0.0
ctu2 Cytoplasmic tRNA 2-thiolation protein 2 Oryzias latipes
TI:8090 None
   
A0A3B6KD99_WHEAT
EnsemblPlants»
0.0
Cytoplasmic tRNA 2-thiolation protein 2 Triticum aestivum
TI:4565 None
   
A0A3B6LH35_WHEAT
EnsemblPlants»
0.0
CFC21_070224 CFC21_070226 Cytoplasmic tRNA 2-thiolation protein 2 Triticum aestivum
TI:4565 None
 
A0A3B6MLK3_WHEAT
EnsemblPlants»
0.0
CFC21_076190 Cytoplasmic tRNA 2-thiolation protein 2 Triticum aestivum
TI:4565 None
 
A0A3Q2U523_CHICK
Ensembl»
1.0
CTU2 Cytoplasmic tRNA 2-thiolation protein 2 Gallus gallus
TI:9031 None
   
A0A3Q7IKV1_SOLLC
EnsemblPlants»
0.0
Cytoplasmic tRNA 2-thiolation protein 2 Solanum lycopersicum
TI:4081 None
   
A0A3Q7ILB3_SOLLC
EnsemblPlants»
0.0
Cytoplasmic tRNA 2-thiolation protein 2 Solanum lycopersicum
TI:4081 None
   
A0A5F5XS41_FELCA
Ensembl»
0.0
CTU2 Cytoplasmic tRNA 2-thiolation protein 2 Felis catus
TI:9685 None
 
A0A5F8AJ46_MACMU
Ensembl»
0.0
CTU2 Cytoplasmic tRNA 2-thiolation protein 2 Macaca mulatta
TI:9544 None
   
A0A7M7N5R9_STRPU
EnsemblMetazoa»
0.0
Cytoplasmic tRNA 2-thiolation protein 2 Strongylocentrotus purpuratus
TI:7668 None
   
A0A804I4C3_MUSAM
EnsemblPlants»
0.0
103975313 Cytoplasmic tRNA 2-thiolation protein 2 Musa acuminata
TI:4641 None
 
A0A8I3MPI7_CANLF
Ensembl»
0.0
CTU2 Cytoplasmic tRNA 2-thiolation protein 2 Canis lupus
TI:9612 None
   
A0A8J0U637_XENLA
Xenbase»
0.0
ctu2.L Cytoplasmic tRNA 2-thiolation protein 2 Xenopus laevis
TI:8355 None
   
A0A9J7MGZ0_BRAFL
CTD»
0.0
LOC118409936 Cytoplasmic tRNA 2-thiolation protein 2 Branchiostoma floridae
TI:7739 None
   
A0D2Q6_PARTE
EnsemblProtists»
0.0
GSPATT00012831001 Cytoplasmic tRNA 2-thiolation protein 2 Paramecium tetraurelia
TI:5888 None
 
A2E8M1_TRIV3
VEuPathDB»
0.0
TVAG_446620 Cytoplasmic tRNA 2-thiolation protein 2 Trichomonas vaginalis
TI:5722 None
 
A7S1L5_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g229188 Cytoplasmic tRNA 2-thiolation protein 2 Nematostella vectensis
TI:45351 None
 
A9US91_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_31190 Cytoplasmic tRNA 2-thiolation protein 2 Monosiga brevicollis
TI:81824 None
 
B3RVD1_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_55610 Cytoplasmic tRNA 2-thiolation protein 2 Trichoplax adhaerens
TI:10228 None
 
B6K0A9_SCHJY
EnsemblFungi»
0.0
NCS2 Cytoplasmic tRNA 2-thiolation protein 2 Schizosaccharomyces japonicus
TI:4897 None
 
B7PNH8_IXOSC
EnsemblMetazoa»
0.0
8053678 Cytoplasmic tRNA 2-thiolation protein 2 Ixodes scapularis
TI:6945 None
 
B7ZWV4_MAIZE
EnsemblPlants»
0.0
100279201 Cytoplasmic tRNA 2-thiolation protein 2 Zea mays
TI:4577 None
 
C5YQV7_SORBI
EnsemblPlants»
0.0
SORBI_3008G147700 Cytoplasmic tRNA 2-thiolation protein 2 Sorghum bicolor
TI:4558 None
 
CTU2_ANOGA
CTD»
0.0
AGAP005651 Cytoplasmic tRNA 2-thiolation protein 2 Anopheles gambiae
TI:7165 None
 
CTU2_ARATH
TAIR»
2.4
CTU2 Cytoplasmic tRNA 2-thiolation protein 2 Arabidopsis thaliana
TI:3702 None
 
CTU2_ASHGO
EnsemblFungi»
0.0
NCS2 Cytoplasmic tRNA 2-thiolation protein 2 Ashbya gossypii
TI:33169 None
 
CTU2_ASPFU
EnsemblFungi»
0.0
ncs2 Cytoplasmic tRNA 2-thiolation protein 2 Aspergillus fumigatus
TI:746128 None
 
CTU2_BOVIN
Ensembl»
0.0
CTU2 Cytoplasmic tRNA 2-thiolation protein 2 Bos taurus
TI:9913 None
 
CTU2_CANAL
EnsemblFungi»
0.0
NCS2 Cytoplasmic tRNA 2-thiolation protein 2 Candida albicans
TI:5476 None
 
CTU2_DANRE
ZFIN»
2.0
ctu2 Cytoplasmic tRNA 2-thiolation protein 2 Danio rerio
TI:7955 None
 
CTU2_DICDI
dictyBase»
2.9
ctu2 Cytoplasmic tRNA 2-thiolation protein 2 Dictyostelium discoideum
TI:44689 None
 
CTU2_DROME
FlyBase»
2.0
CG10189 Cytoplasmic tRNA 2-thiolation protein 2 Drosophila melanogaster
TI:7227 None
 
CTU2_EMENI
VEuPathDB»
0.0
ncs2 Cytoplasmic tRNA 2-thiolation protein 2 Emericella nidulans
TI:162425 None
 
CTU2_MOUSE
Ensembl»
1.0
Ctu2 Cytoplasmic tRNA 2-thiolation protein 2 Mus musculus
TI:10090 None
 
CTU2_ORYSJ
EnsemblPlants»
0.0
CTU2 Cytoplasmic tRNA 2-thiolation protein 2 Oryza sativa
TI:4530 None
 
CTU2_RAT
RGD»
2.0
Ctu2 Cytoplasmic tRNA 2-thiolation protein 2 Rattus norvegicus
TI:10116 None
 
CTU2_SCHPO
PomBase»
2.6
ctu2 Cytoplasmic tRNA 2-thiolation protein 2 Schizosaccharomyces pombe
TI:4896 None
 
CTU2_SCLS1
EnsemblFungi»
0.0
ncs2 Cytoplasmic tRNA 2-thiolation protein 2 Sclerotinia sclerotiorum
TI:5180 None
 
CTU2_XENTR
Xenbase»
0.0
ctu2 Cytoplasmic tRNA 2-thiolation protein 2 Xenopus tropicalis
TI:8364 None
 
CTU2_YARLI
EnsemblFungi»
0.0
NCS2 Cytoplasmic tRNA 2-thiolation protein 2 Yarrowia lipolytica
TI:4952 None
 
D6WYA9_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_15985 Cytoplasmic tRNA 2-thiolation protein 2 Tribolium castaneum
TI:7070 None
 
D7THW2_VITVI
EnsemblPlants»
0.0
VIT_08s0007g08560 Cytoplasmic tRNA 2-thiolation protein 2 Vitis vinifera
TI:29760 None
 
E3KVI1_PUCGT
EnsemblFungi»
0.0
NCS2 Cytoplasmic tRNA 2-thiolation protein 2 Puccinia graminis
TI:5297 None
 
E9G223_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_308415 Cytoplasmic tRNA 2-thiolation protein 2 Daphnia pulex
TI:6669 None
 
F2EH71_HORVV
EnsemblPlants»
0.0
Cytoplasmic tRNA 2-thiolation protein 2 Hordeum vulgare
TI:4513 None
 
F4PCS6_BATDJ
EnsemblBacteria»
0.0
NCS2 Cytoplasmic tRNA 2-thiolation protein 2 Batrachochytrium dendrobatidis
TI:109871 None
 
F6Q4L9_CIOIN
Ensembl»
0.0
Cytoplasmic tRNA 2-thiolation protein 2 Ciona intestinalis
TI:7719 None
 
F6W988_HORSE
Ensembl»
0.0
CTU2 Cytoplasmic tRNA 2-thiolation protein 2 Equus caballus
TI:9796 None
   
F7B1B4_MONDO
Ensembl»
0.0
CTU2 Cytoplasmic tRNA 2-thiolation protein 2 Monodelphis domestica
TI:13616 None
   
F7GBQ9_ORNAN
Ensembl»
0.0
CTU2 Cytoplasmic tRNA 2-thiolation protein 2 Ornithorhynchus anatinus
TI:9258 None
   
G3RA16_GORGO
Ensembl»
0.0
CTU2 Cytoplasmic tRNA 2-thiolation protein 2 Gorilla gorilla
TI:9593 None
 
H2QBQ4_PANTR
Ensembl»
0.0
CTU2 Cytoplasmic tRNA 2-thiolation protein 2 Pan troglodytes
TI:9598 None
 
H9GBW8_ANOCA
Ensembl»
0.0
CTU2 Cytoplasmic tRNA 2-thiolation protein 2 Anolis carolinensis
TI:28377 None
   
I1IGZ5_BRADI
EnsemblPlants»
0.0
100821158 Cytoplasmic tRNA 2-thiolation protein 2 Brachypodium distachyon
TI:15368 None
 
I1JND0_SOYBN
EnsemblPlants»
0.0
100804325 Cytoplasmic tRNA 2-thiolation protein 2 Glycine max
TI:3847 None
 
K3Z616_SETIT
EnsemblPlants»
0.0
101774702 Cytoplasmic tRNA 2-thiolation protein 2 Setaria italica
TI:4555 None
 
K7MYC1_SOYBN
EnsemblPlants»
0.0
GLYMA_19G139200 Cytoplasmic tRNA 2-thiolation protein 2 Glycine max
TI:3847 None
 
M1C6M6_SOLTU
EnsemblPlants»
0.0
102586394 Cytoplasmic tRNA 2-thiolation protein 2 Solanum tuberosum
TI:4113 None
   
M4D5F7_BRACM
EnsemblPlants»
0.0
Cytoplasmic tRNA 2-thiolation protein 2 Brassica campestris
TI:3711 None
   
M5VWT1_PRUPE
EnsemblPlants»
0.0
PRUPE_7G060900 Cytoplasmic tRNA 2-thiolation protein 2 Prunus persica
TI:3760 None
 
Q386A9_TRYB2
VEuPathDB»
0.0
Tb11.02.1560 Cytoplasmic tRNA 2-thiolation protein 2 Trypanosoma brucei
TI:5691 None
 
Q4QG75_LEIMA
EnsemblProtists»
0.0
LMJF_13_0790 Cytoplasmic tRNA 2-thiolation protein 2 Leishmania major
TI:5664 None
 
Q5KJL1_CRYNJ
EnsemblFungi»
0.0
NCS2 Cytoplasmic tRNA 2-thiolation protein 2 Cryptococcus neoformans
TI:5207 None
 
T1FVS8_HELRO
EnsemblMetazoa»
0.0
20212924 Cytoplasmic tRNA 2-thiolation protein 2 Helobdella robusta
TI:6412 None
 
U9W2Q7_NEUCR
EnsemblFungi»
0.0
NCS2 Cytoplasmic tRNA 2-thiolation protein 2 Neurospora crassa
TI:5141 None
 
W1PIJ8_AMBTC
EnsemblPlants»
0.0
AMTR_s00005p00261900 Cytoplasmic tRNA 2-thiolation protein 2 Amborella trichopoda
TI:13333 None
 
W5MBQ4_LEPOC
Ensembl»
0.0
CTU2 Cytoplasmic tRNA 2-thiolation protein 2 Lepisosteus oculatus
TI:7918 None
 
CTU2_HUMAN
Ensembl»
2.2
CTU2 Cytoplasmic tRNA 2-thiolation protein
2 (Cytosolic thiouridylase subunit 2)		 Homo sapiens
TI:9606 None
 
Q8IL60_PLAF7
EnsemblProtists»
0.0
PF3D7_1441000 Cytoplasmic tRNA 2-thiolation
protein 2, putative		 Plasmodium falciparum
TI:5833 None