Collated Gene Ontology terms

Biological process: pseudouridine synthase activity(2011, 2022, 2025) tRNA pseudouridine(55) synthase activity(2025) isomerase activity(2025) RNA binding(2025) tRNA pseudouridine synthase activity(2020, 2022, 2023, 2025) primary miRNA binding(2022, 2025) metal ion binding(2025) tRNA binding(2025)

Molecular function: tRNA pseudouridine synthesis2011, 2017, 2020, 2025 tRNA processing2025 pseudouridine synthesis2025 RNA modification2025 primary miRNA processing2020, 2025 tRNA modification2025

Cellular component: nucleus2018, 2020, 2025 cytoplasm2020, 2024, 2025 mitochondrion2025 cytosol2025 chloroplast2022, 2025 nuclear lumen2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 4/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 7/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

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Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
PUS10_HUMAN
Ensembl»
6.6
PUS10 tRNA pseudouridine synthase Pus10 (Hup10) (EC 5.4.99.25) (Coiled-coil domain-containing protein 139)
(tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase)		 Homo sapiens
TI:9606 None
 
PUS10_MOUSE
Ensembl»
6.5
Pus10 tRNA pseudouridine synthase Pus10 (EC 5.4.99.25) (Coiled-coil domain-containing protein 139)
(tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase)		 Mus musculus
TI:10090 None
 
A0A0G2K0U8_RAT
RGD»
4.0
Pus10 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Rattus norvegicus
TI:10116 None
   
PUS10_DROME
FlyBase»
1.5
Pus10 Putative tRNA pseudouridine synthase Pus10 (EC 5.4.99.25) (Coiled-coil domain-containing protein 139
homolog) (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase)		 Drosophila melanogaster
TI:7227 None
 
A8KB22_DANRE
ZFIN»
1.0
pus10 tRNA pseudouridine synthase Pus10 (EC 5.4.99.25) (tRNA
pseudouridine 55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase)		 Danio rerio
TI:7955 None
 
E1C8Y6_CHICK
Ensembl»
1.0
PUS10 tRNA pseudouridine synthase Pus10 (EC 5.4.99.25) (tRNA
pseudouridine 55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase)		 Gallus gallus
TI:9031 None
   
F4HSS8_ARATH
TAIR»
1.0
At1g20410 tRNA pseudouridine(55) synthase (EC 5.4.99.25) (tRNA pseudouridine
55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase)		 Arabidopsis thaliana
TI:3702 None
 
Q55G71_DICDI
dictyBase»
1.0
DDB_G0267794 tRNA pseudouridine(55) synthase (EC 5.4.99.25) (tRNA pseudouridine
55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase)		 Dictyostelium discoideum
TI:44689 None
 
Q9U287_CAEEL
WormBase»
1.0
CELE_Y48C3A.20 Y48C3A.20 tRNA pseudouridine(55) synthase (EC 5.4.99.25) (tRNA pseudouridine
55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase)		 Caenorhabditis elegans
TI:6239 None