Collated Gene Ontology terms

Biological process: pseudouridine synthase activity(2011, 2022, 2024) isomerase activity(2024) RNA binding(2024) tRNA pseudouridine(55) synthase activity(2024) tRNA pseudouridine synthase activity(2020, 2022, 2023, 2024) primary miRNA binding(2022, 2024) tRNA binding(2024) metal ion binding(2024)

Molecular function: tRNA pseudouridine synthesis2011, 2017, 2020, 2024 tRNA processing2024 pseudouridine synthesis2024 primary miRNA processing2020, 2024 tRNA modification2024

Cellular component: nucleus2020, 2024 cytoplasm2020, 2024 mitochondrion2024 membrane2024

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 4/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 7/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
PUS10_HUMAN
Ensembl»
5.0
PUS10 tRNA pseudouridine synthase Pus10 (Hup10) (EC 5.4.99.25) (Coiled-coil domain-containing protein 139)
(tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase)		 Homo sapiens
TI:9606 None
 
A0A0G2K0U8_RAT
RGD»
3.5
Pus10 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Rattus norvegicus
TI:10116 None
   
PUS10_MOUSE
Ensembl»
2.5
Pus10 tRNA pseudouridine synthase Pus10 (EC 5.4.99.25) (Coiled-coil domain-containing protein 139)
(tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase)		 Mus musculus
TI:10090 None
 
PUS10_DROME
FlyBase»
1.5
Pus10 Putative tRNA pseudouridine synthase Pus10 (EC 5.4.99.25) (Coiled-coil domain-containing protein 139
homolog) (tRNA pseudouridine 55 synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase)		 Drosophila melanogaster
TI:7227 None
 
A8KB22_DANRE
ZFIN»
1.0
pus10 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Danio rerio
TI:7955 None
 
E1C8Y6_CHICK
Ensembl»
1.0
PUS10 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Gallus gallus
TI:9031 None
   
Q55G71_DICDI
dictyBase»
1.0
DDB_G0267794 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Dictyostelium discoideum
TI:44689 None
 
Q9U287_CAEEL
WormBase»
1.0
CELE_Y48C3A.20 Y48C3A.20 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Caenorhabditis elegans
TI:6239 None
 
A0A022R960_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a003989mg tRNA pseudouridine(55) synthase (EC 5.4.99.25) Erythranthe guttata
TI:4155 None
 
A0A061FDT4_THECC
EnsemblPlants»
0.0
TCM_034331 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Theobroma cacao
TI:3641 None
 
A0A067HBC2_CITSI
Ensembl»
0.0
CISIN_1g008562mg tRNA pseudouridine(55) synthase (EC 5.4.99.25) Citrus sinensis
TI:2711 None
 
A0A072VEM5_MEDTR
EnsemblPlants»
0.0
25482221 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Medicago truncatula
TI:3880 None
 
A0A078GVL2_BRANA
EnsemblPlants»
0.0
BnaA06g14390D tRNA pseudouridine(55) synthase (EC 5.4.99.25) Brassica napus
TI:3708 None
 
A0A078GZI7_BRANA
EnsemblPlants»
0.0
BnaC07g15400D tRNA pseudouridine(55) synthase (EC 5.4.99.25) Brassica napus
TI:3708 None
 
A0A078H120_BRANA
EnsemblPlants»
0.0
BnaC05g15750D tRNA pseudouridine(55) synthase (EC 5.4.99.25) Brassica napus
TI:3708 None
 
A0A0A0L378_CUCSA
EnsemblPlants»
0.0
Csa_4G653400 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Cucumis sativus
TI:3659 None
 
A0A0K9PEJ9_ZOSMR
EnsemblPlants»
0.0
ZOSMA_26G01500 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Zostera marina
TI:29655 None
 
A0A0Q3ID77_BRADI
EnsemblPlants»
0.0
100822088 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Brachypodium distachyon
TI:15368 None
 
A0A139WB62_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_34869 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Tribolium castaneum
TI:7070 None
 
A0A1B6PMK9_SORBI
EnsemblPlants»
0.0
SORBI_3006G178100 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Sorghum bicolor
TI:4558 None
 
A0A1D6E3B3_MAIZE
EnsemblPlants»
0.0
ZEAMMB73_Zm00001d002676 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Zea mays
TI:4577 None
 
A0A1S3WXN5_TOBAC
EnsemblFungi»
0.0
LOC107759032 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Nicotiana tabacum
TI:4097 None
   
A0A1S3Z003_TOBAC
EnsemblFungi»
0.0
LOC107781503 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Nicotiana tabacum
TI:4097 None
   
A0A1S4H980_ANOGA
EnsemblMetazoa»
0.0
tRNA pseudouridine(55) synthase (EC 5.4.99.25) Anopheles gambiae
TI:7165 None
 
A0A1U8ASM8_NELNU
EnsemblBacteria»
0.0
LOC104603700 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Nelumbo nucifera
TI:4432 None
 
A0A1U8JBZ8_GOSHI
Ensembl»
0.0
LOC107905638 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Gossypium hirsutum
TI:3635 None
   
A0A1U8MGH0_GOSHI
Ensembl»
0.0
LOC107937555 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Gossypium hirsutum
TI:3635 None
   
A0A1Y1I146_KLENI
EnsemblPlants»
0.0
KFL_001980170 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Klebsormidium nitens
TI:105231 None
 
A0A251R866_PRUPE
EnsemblPlants»
0.0
PRUPE_1G357400 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Prunus persica
TI:3760 None
 
A0A251SF81_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr14g0428991 HanXRQr2_Chr14g0622081 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Helianthus annuus
TI:4232 None
 
A0A2C9U085_MANES
EnsemblPlants»
0.0
MANES_18G007800 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Manihot esculenta
TI:3983 None
 
A0A2G2ZSS0_CAPAN
EnsemblPlants»
0.0
T459_13457 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Capsicum annuum
TI:4072 None
 
A0A2K1IUW6_PHYPA
EnsemblPlants»
0.0
PHYPA_025014 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Physcomitrium patens
TI:3218 None
 
A0A2K2AM15_POPTR
EnsemblPlants»
0.0
POPTR_005G247500 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Populus trichocarpa
TI:3694 None
 
A0A2K3D2W1_CHLRE
EnsemblPlants»
0.0
CHLRE_12g506900v5 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Chlamydomonas reinhardtii
TI:3055 None
 
A0A2R6XPE2_MARPO
EnsemblPlants»
0.0
MARPO_0006s0010 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Marchantia polymorpha
TI:3197 None
 
A0A3B6B4F3_WHEAT
EnsemblPlants»
0.0
tRNA pseudouridine(55) synthase (EC 5.4.99.25) Triticum aestivum
TI:4565 None
   
A0A3B6CAV2_WHEAT
EnsemblPlants»
0.0
CFC21_024849 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Triticum aestivum
TI:4565 None
 
A0A3B6DI19_WHEAT
EnsemblPlants»
0.0
CFC21_031165 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Triticum aestivum
TI:4565 None
 
A0A3Q7G8G1_SOLLC
EnsemblPlants»
0.0
101251773 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Solanum lycopersicum
TI:4081 None
   
A0A6P9DSZ8_JUGRE
EnsemblPlants»
0.0
LOC108984520 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Juglans regia
TI:51240 None
   
A0A7M7PRN6_STRPU
EnsemblMetazoa»
0.0
tRNA pseudouridine(55) synthase (EC 5.4.99.25) Strongylocentrotus purpuratus
TI:7668 None
   
A0A803T6U5_ANOCA
Ensembl»
0.0
PUS10 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Anolis carolinensis
TI:28377 None
   
A0A804ISN4_MUSAM
EnsemblPlants»
0.0
tRNA pseudouridine(55) synthase (EC 5.4.99.25) Musa acuminata
TI:4641 None
   
A0A8I3RXG6_CANLF
Ensembl»
0.0
PUS10 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Canis lupus
TI:9612 None
   
A0A8I6WRK1_HORVV
EnsemblPlants»
0.0
tRNA pseudouridine(55) synthase (EC 5.4.99.25) Hordeum vulgare
TI:4513 None
   
A0A8R1UGU6_PRIPA
EnsemblMetazoa»
0.0
WBGene00117729 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Pristionchus pacificus
TI:54126 None
   
A0A9J7M9C2_BRAFL
CTD»
0.0
LOC118429528 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Branchiostoma floridae
TI:7739 None
   
A0BYF6_PARTE
EnsemblProtists»
0.0
GSPATT00033426001 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Paramecium tetraurelia
TI:5888 None
 
A0CTG5_PARTE
EnsemblProtists»
0.0
GSPATT00010316001 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Paramecium tetraurelia
TI:5888 None
 
A2DP52_TRIV3
VEuPathDB»
0.0
TVAG_015810 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Trichomonas vaginalis
TI:5722 None
 
A7STU7_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g131503 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Nematostella vectensis
TI:45351 None
 
A7T450_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g222064 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Nematostella vectensis
TI:45351 None
 
A8BK32_GIAIC
EnsemblProtists»
0.0
GL50803_0087208 GL50803_87208 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Giardia intestinalis
TI:5741 None
 
B3RJI9_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_52642 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Trichoplax adhaerens
TI:10228 None
 
B5YNA4_THAPS
EnsemblProtists»
0.0
THAPS_23513 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Thalassiosira pseudonana
TI:35128 None
 
B7PYG2_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW009152 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Ixodes scapularis
TI:6945 None 		 
 
B7PYG3_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW009153 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Ixodes scapularis
TI:6945 None
 
B9FBY4_ORYSJ
EnsemblPlants»
0.0
Os04g0561700 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Oryza sativa
TI:4530 None
 
B9R8I1_RICCO
EnsemblBacteria»
0.0
RCOM_1599990 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Ricinus communis
TI:3988 None
 
C4LXV5_ENTH1
EnsemblProtists»
0.0
EHI_087750 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Entamoeba histolytica
TI:5759 None
 
D6W8D0_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_01704 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Tribolium castaneum
TI:7070 None
 
D8QTY7_SELML
EnsemblPlants»
0.0
SELMODRAFT_76713 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Selaginella moellendorffii
TI:88036 None
 
D8RJN6_SELML
EnsemblPlants»
0.0
SELMODRAFT_441456 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Selaginella moellendorffii
TI:88036 None
 
E9H2F9_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_324687 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Daphnia pulex
TI:6669 None
 
F0ZPK9_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_98330 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Dictyostelium purpureum
TI:5786 None
 
F1MRD5_BOVIN
Ensembl»
0.0
PUS10 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Bos taurus
TI:9913 None
   
F1SQM1_PIG
Ensembl»
0.0
PUS10 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Sus scrofa
TI:9823 None
   
F4HSS8_ARATH
TAIR»
0.0
At1g20410 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Arabidopsis thaliana
TI:3702 None
 
F4P7R3_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_90402 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Batrachochytrium dendrobatidis
TI:109871 None
 
F6H0C9_VITVI
EnsemblPlants»
0.0
VIT_18s0001g00500 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Vitis vinifera
TI:29760 None
 
F6PH90_CIOIN
Ensembl»
0.0
LOC100183355 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Ciona intestinalis
TI:7719 None
   
F6U5F7_MACMU
Ensembl»
0.0
PUS10 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Macaca mulatta
TI:9544 None
   
F7A253_HORSE
Ensembl»
0.0
PUS10 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Equus caballus
TI:9796 None
   
F7G3Q0_MONDO
Ensembl»
0.0
PUS10 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Monodelphis domestica
TI:13616 None
   
G2J716_CAEBR
WormBase»
0.0
CBG20788 CBG20791 CBG_20788 CBG_20791 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Caenorhabditis briggsae
TI:6238 None
 
G3SCS6_GORGO
Ensembl»
0.0
PUS10 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Gorilla gorilla
TI:9593 None
 
H2L7K7_ORYLA
Ensembl»
0.0
pus10 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Oryzias latipes
TI:8090 None
   
H2QHY3_PANTR
Ensembl»
0.0
PUS10 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Pan troglodytes
TI:9598 None
 
H3HD02_PHYRM
EnsemblProtists»
0.0
tRNA pseudouridine(55) synthase (EC 5.4.99.25) Phytophthora ramorum
TI:164328 None
 
I1HZQ7_BRADI
EnsemblPlants»
0.0
BRADI_3g10850v3 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Brachypodium distachyon
TI:15368 None
 
I1IQK4_BRADI
EnsemblPlants»
0.0
BRADI_4g31650v3 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Brachypodium distachyon
TI:15368 None
 
I1MBZ8_SOYBN
EnsemblPlants»
0.0
100780683 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Glycine max
TI:3847 None
 
K3Y6N5_SETIT
EnsemblPlants»
0.0
tRNA pseudouridine(55) synthase (EC 5.4.99.25) Setaria italica
TI:4555 None
 
K7EEN0_ORNAN
Ensembl»
0.0
PUS10 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Ornithorhynchus anatinus
TI:9258 None
   
M1AM34_SOLTU
EnsemblPlants»
0.0
102587777 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Solanum tuberosum
TI:4113 None
   
M3W8T7_FELCA
Ensembl»
0.0
PUS10 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Felis catus
TI:9685 None
 
M4D6W8_BRACM
EnsemblPlants»
0.0
tRNA pseudouridine(55) synthase (EC 5.4.99.25) Brassica campestris
TI:3711 None
   
M4EAK8_BRACM
EnsemblPlants»
0.0
tRNA pseudouridine(55) synthase (EC 5.4.99.25) Brassica campestris
TI:3711 None
   
PUS10_KORCO
EnsemblBacteria»
0.0
pus10 tRNA pseudouridine synthase Pus10 (EC 5.4.99.25)
(tRNA pseudouridine 54/55 synthase) (Psi54/55 synthase)		 Korarchaeum cryptofilum
TI:498846 None
 
PUS10_METJA
EnsemblBacteria»
0.0
pus10 tRNA pseudouridine synthase Pus10 (EC 5.4.99.25)
(tRNA pseudouridine 54/55 synthase) (Psi54/55 synthase)		 Methanocaldococcus jannaschii
TI:2190 None
 
PUS10_NITMS
EnsemblBacteria»
0.0
pus10 tRNA pseudouridine synthase Pus10 (EC 5.4.99.25)
(tRNA pseudouridine 54/55 synthase) (Psi54/55 synthase)		 Nitrosopumilus maritimus
TI:338192 None
 
PUS10_XENLA
Xenbase»
0.0
pus10 tRNA pseudouridine synthase Pus10 (EC 5.4.99.25) (tRNA pseudouridine
55 synthase) (Psi55 synthase) (tRNA pseudouridylate synthase) (tRNA-uridine isomerase)		 Xenopus laevis
TI:8355 None
 
Q07GA4_XENTR
Xenbase»
0.0
pus10 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Xenopus tropicalis
TI:8364 None 		 
 
Q385A2_TRYB2
VEuPathDB»
0.0
Tb11.02.4510 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Trypanosoma brucei
TI:5691 None
 
Q4QH27_LEIMA
EnsemblProtists»
0.0
LMJF_11_0530 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Leishmania major
TI:5664 None
 
Q5JI50_THEKO
EnsemblBacteria»
0.0
pus10 tRNA pseudouridine synthase Pus10 (EC 5.4.99.25)
(tRNA pseudouridine 54/55 synthase) (Psi54/55 synthase)		 Thermococcus kodakarensis
TI:311400 None
 
Q8IM68_PLAF7
EnsemblProtists»
0.0
PF3D7_1402100 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Plasmodium falciparum
TI:5833 None
 
Q8TQU2_METAC
EnsemblBacteria»
0.0
pus10 tRNA pseudouridine synthase Pus10 (EC 5.4.99.25)
(tRNA pseudouridine 54/55 synthase) (Psi54/55 synthase)		 Methanosarcina acetivorans
TI:2214 None
 
Q8ZT93_PYRAE
EnsemblBacteria»
0.0
pus10 tRNA pseudouridine synthase Pus10 (EC 5.4.99.25)
(tRNA pseudouridine 54/55 synthase) (Psi54/55 synthase)		 Pyrobaculum aerophilum
TI:13773 None
 
Q9HNR4_HALSA
EnsemblBacteria»
0.0
pus10 tRNA pseudouridine synthase Pus10 (EC 5.4.99.25)
(tRNA pseudouridine 54/55 synthase) (Psi54/55 synthase)		 Halobacterium salinarum
TI:2242 None
 
T1FF92_HELRO
EnsemblMetazoa»
0.0
20207491 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Helobdella robusta
TI:6412 None
 
W1P0U5_AMBTC
EnsemblPlants»
0.0
AMTR_s00002p00244810 tRNA pseudouridine(55) synthase (EC 5.4.99.25) Amborella trichopoda
TI:13333 None
 
W5NGV8_LEPOC
Ensembl»
0.0
tRNA pseudouridine(55) synthase (EC 5.4.99.25) Lepisosteus oculatus
TI:7918 None