Collated Gene Ontology terms

Biological process: chromatin binding(2010) 3'-5' DNA helicase activity(2020)

Molecular function: DNA replication2010, 2020, 2024, 2025 double-strand break repair via break-induced replication2013, 2017, 2025 chromosome segregation2016, 2025 nuclear DNA replication2004, 2025 DNA-templated DNA replication2013, 2025 DNA replication initiation2009, 2016, 2020 regulation of DNA-templated transcription elongation2003, 2004 DNA strand elongation involved in DNA replication2003, 2004 chromosome condensation2013 cell cycle DNA replication2016

Cellular component: GINS complex2007, 2010, 2013, 2016, 2020, 2025 nucleus2003, 2004, 2009, 2013, 2016, 2018, 2020, 2024, 2025 nuclear chromosome2025 CMG complex2016, 2017, 2020, 2025 nuclear replication fork2009, 2024, 2025 chromatin2014, 2025 chromosome2025 DNA replication preinitiation complex2013, 2025 nucleoplasm2006, 2013, 2025 cytosol2009
cytoplasm2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 4/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
PSF2_HUMAN
Ensembl»
1.9
GINS2 DNA replication complex GINS protein
PSF2 (GINS complex subunit 2)		 Homo sapiens
TI:9606 None
 
PSF2_ARATH
TAIR»
0.5
GINS2 DNA replication complex GINS protein PSF2 Arabidopsis thaliana
TI:3702 None
 
PSF2_YEAST
SGD»
4.3
PSF2 DNA replication complex GINS protein
PSF2 (Partner of Sld five 2)		 Saccharomyces cerevisiae
TI:4932 None
 
A0A0R0FVX5_SOYBN
EnsemblPlants»
0.0
LOC100780528 DNA replication complex GINS protein PSF2 Glycine max
TI:3847 None
 
PSF2_MOUSE
Ensembl»
1.6
Gins2 DNA replication complex GINS protein
PSF2 (GINS complex subunit 2)		 Mus musculus
TI:10090 None
 
I3SFH0_MEDTR
EnsemblPlants»
0.0
25497860 DNA replication complex GINS protein PSF2 Medicago truncatula
TI:3880 None
 
PSF2_DROME
FlyBase»
4.7
Psf2 Probable DNA replication complex GINS
protein PSF2 (GINS complex subunit 2)		 Drosophila melanogaster
TI:7227 None
 
Q9FTK2_ORYSJ
neXtProt»
0.0
Os01g0248600 DNA replication complex GINS protein PSF2 Oryza sativa
TI:4530 None
 
A0A061FNA9_THECC
neXtProt»
0.0
TCM_042758 DNA replication complex GINS protein PSF2 Theobroma cacao
TI:3641 None
 
A0A251RX15_HELAN
neXtProt»
0.0
PSF2 DNA replication complex GINS protein PSF2 Helianthus annuus
TI:4232 None
 
B4FLH9_MAIZE
EnsemblPlants»
0.0
LOC100280623 DNA replication complex GINS protein PSF2 Zea mays
TI:4577 None
 
PSF2_EMENI
TubercuList»
0.0
psf2 DNA replication complex GINS protein psf2 Emericella nidulans
TI:162425 None
 
PSF2_NEUCR
EnsemblFungi»
0.0
drc-2 DNA replication complex GINS protein
psf2 (DNA replication complex protein 2)		 Neurospora crassa
TI:5141 None
 
PSF2_XENLA
CTD»
0.0
gins2 DNA replication complex GINS protein
PSF2 (GINS complex subunit 2)		 Xenopus laevis
TI:8355 None
 
Q4VBJ6_DANRE
ZFIN»
0.5
gins2 DNA replication complex GINS protein PSF2 Danio rerio
TI:7955 None
 
Q5EB27_XENTR
Xenbase»
0.0
gins2 DNA replication complex GINS protein PSF2 Xenopus tropicalis
TI:8364 None
 
T1G2N2_HELRO
EnsemblMetazoa»
0.0
20215330 DNA replication complex GINS protein PSF2 Helobdella robusta
TI:6412 None
 
A0A022QLV8_ERYGU
neXtProt»
0.0
MIMGU_mgv1a025058mg DNA replication complex GINS protein PSF2 Erythranthe guttata
TI:4155 None
 
A0A067FT24_CITSI
euHCVdb»
0.0
CISIN_1g048544mg Uncharacterized protein Citrus sinensis
TI:2711 None
 
A0A078HWG1_BRANA
neXtProt»
0.0
BnaC05g40670D BnaC05g40670D protein Brassica napus
TI:3708 None
 
A0A0A0KVY8_CUCSA
neXtProt»
0.0
Csa_4G114190 DNA replication complex GINS
protein PSF2 N-terminal domain-containing protein		 Cucumis sativus
TI:3659 None
 
A0A0A0L0R7_CUCSA
euHCVdb»
0.0
Csa_4G113680 GINS subunit domain-containing protein Cucumis sativus
TI:3659 None
 
A0A0K9NKB3_ZOSMR
neXtProt»
0.0
ZOSMA_88G00250 DNA replication complex GINS protein PSF2 Zostera marina
TI:29655 None
 
A0A1U8GTG0_CAPAN
neXtProt»
0.0
T459_15445 DNA replication complex GINS protein PSF2 Capsicum annuum
TI:4072 None
 
A0A1W0W847_SORBI
neXtProt»
0.0
SORBI_3002G430200 DNA replication complex GINS protein PSF2 Sorghum bicolor
TI:4558 None
 
A0A1Y1I339_KLENI
neXtProt»
0.0
KFL_001370260 Uncharacterized protein Klebsormidium nitens
TI:105231 None
 
A0A251QKV7_PRUPE
neXtProt»
0.0
PRUPE_2G235900 DNA replication complex GINS protein PSF2 Prunus persica
TI:3760 None
 
A0A251SL19_HELAN
neXtProt»
0.0
HannXRQ_Chr14g0458031 Putative GINS complex Helianthus annuus
TI:4232 None
 
A0A2C9VM20_MANES
neXtProt»
0.0
MANES_07G116600v8 DNA replication complex GINS protein PSF2 Manihot esculenta
TI:3983 None
 
A0A2K1YXF4_POPTR
neXtProt»
0.0
POPTR_010G203600 DNA replication complex GINS protein PSF2 Populus trichocarpa
TI:3694 None
 
A0A2K3E6K5_CHLRE
euHCVdb»
0.0
CHLRE_01g029100v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A2R6XVQ3_MARPO
euHCVdb»
0.0
MARPO_0001s0197 DNA replication complex GINS protein PSF2 Marchantia polymorpha
TI:3197 None
 
A0A3N7GYE6_POPTR
neXtProt»
0.0
POPTR_008G056200 Uncharacterized protein Populus trichocarpa
TI:3694 None
 
A0A7I4CL67_PHYPA
EnsemblPlants»
0.0
LOC112276967 DNA replication complex GINS protein PSF2 Physcomitrium patens
TI:3218 None
 
A0A7U2FB16_PHANO
TubercuList»
0.0
JI435_049730 DNA replication complex GINS protein PSF2 Phaeosphaeria nodorum
TI:13684 None
 
A0A9K3H7U3_HELAN
neXtProt»
0.0
HanXRQr2_Chr14g0664651 DNA replication complex GINS protein PSF2 Helianthus annuus
TI:4232 None
 
A0A9R1XV76_LACSA
euHCVdb»
0.0
LSAT_V11C100031390 DNA replication complex GINS protein PSF2 Lactuca sativa
TI:4236 None
 
A0CXB0_PARTE
euHCVdb»
0.0
GSPATT00011059001 Uncharacterized protein Paramecium tetraurelia
TI:5888 None
 
A0CZ06_PARTE
neXtProt»
0.0
GSPATT00011624001 Uncharacterized protein Paramecium tetraurelia
TI:5888 None
 
A2EK10_TRIV3
TubercuList»
0.0
TVAG_174630 Partner of SLD five, PSF2 family protein Trichomonas vaginalis
TI:5722 None
 
A7F8M8_SCLS1
euHCVdb»
0.0
SS1G_13959 DNA replication complex GINS protein PSF2 Sclerotinia sclerotiorum
TI:5180 None
 
A7SQT9_NEMVE
neXtProt»
0.0
NEMVEDRAFT_v1g173306 DNA replication complex GINS protein PSF2 Nematostella vectensis
TI:45351 None
 
A8BJN0_GIAIC
TubercuList»
0.0
GL50803_00101943 GINS complex protein Giardia intestinalis
TI:5741 None
 
A8XWD0_CAEBR
WormBase»
0.0
psf-2 DNA replication complex GINS protein PSF2 Caenorhabditis briggsae
TI:6238 None
 
A9UTE2_MONBE
neXtProt»
0.0
MONBRDRAFT_23436 GINS subunit domain-containing protein Monosiga brevicollis
TI:81824 None
 
B3RVT8_TRIAD
CTD»
0.0
TRIADDRAFT_55771 DNA replication complex GINS protein PSF2 Trichoplax adhaerens
TI:10228 None
 
B6JWC2_SCHJY
TubercuList»
0.0
psf2 DNA replication complex GINS protein PSF2 Schizosaccharomyces japonicus
TI:4897 None
 
B8C947_THAPS
euHCVdb»
0.0
THAPSDRAFT_24126 DNA replication complex GINS
protein PSF2 N-terminal domain-containing protein		 Thalassiosira pseudonana
TI:35128 None
 
C0H5F5_PLAF7
TubercuList»
0.0
PF3D7_1335500 DNA replication complex GINS protein, putative Plasmodium falciparum
TI:5833 None
 
C3ZB54_BRAFL
euHCVdb»
0.0
LOC118418602 DNA replication complex GINS protein PSF2 Branchiostoma floridae
TI:7739 None
 
C4LWM2_ENTH1
TubercuList»
0.0
EHI_069340 DNA replication complex GINS protein PSF2 Entamoeba histolytica
TI:5759 None
 
C5XL70_SORBI
euHCVdb»
0.0
SORBI_3003G025100 DNA replication complex GINS protein PSF2 Sorghum bicolor
TI:4558 None
 
D6X0V8_TRICA
neXtProt»
0.0
AUGUSTUS-3.0.2_12816 DNA replication complex GINS protein PSF2 Tribolium castaneum
TI:7070 None
 
D7T7M5_VITVI
neXtProt»
0.0
VIT_16s0039g01780 DNA replication complex GINS protein PSF2 Vitis vinifera
TI:29760 None
 
D8QY03_SELML
neXtProt»
0.0
SELMODRAFT_80420 DNA replication complex GINS protein PSF2 Selaginella moellendorffii
TI:88036 None
 
D8RUR6_SELML
neXtProt»
0.0
SELMODRAFT_101955 DNA replication complex GINS protein PSF2 Selaginella moellendorffii
TI:88036 None
 
E3KLG2_PUCGT
TubercuList»
0.0
PGTG_11306 DNA replication complex GINS protein PSF2
(DNA replication complex GINS protein psf2)		 Puccinia graminis
TI:5297 None
 
E3L2R9_PUCGT
TubercuList»
0.0
PGTG_17034 DNA replication complex GINS protein PSF2
(DNA replication complex GINS protein psf2)		 Puccinia graminis
TI:5297 None
 
E9GHY1_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_50715 DNA replication complex GINS protein PSF2 Daphnia pulex
TI:6669 None
 
F0ZQB8_DICPU
TubercuList»
0.0
DICPUDRAFT_10903 Uncharacterized protein Dictyostelium purpureum
TI:5786 None
 
F0ZVX7_DICPU
TubercuList»
0.0
DICPUDRAFT_39223 DNA replication complex GINS protein PSF2 Dictyostelium purpureum
TI:5786 None
 
F4PBC8_BATDJ
neXtProt»
0.0
BATDEDRAFT_27602 DNA replication complex GINS protein PSF2 Batrachochytrium dendrobatidis
TI:109871 None
 
G3RNK0_GORGO
Ensembl»
0.0
GINS2 DNA replication complex GINS protein PSF2 Gorilla gorilla
TI:9593 None
 
H2QBN2_PANTR
Ensembl»
0.0
GINS2 DNA replication complex GINS protein PSF2 Pan troglodytes
TI:9598 None
 
H2XPE3_CIOIN
Ensembl»
0.0
DNA replication complex GINS protein PSF2 Ciona intestinalis
TI:7719 None
 
H3H255_PHYRM
EnsemblProtists»
0.0
DNA replication complex GINS protein PSF2 Phytophthora ramorum
TI:164328 None
 
I1HVQ3_BRADI
EnsemblPlants»
0.0
LOC100838674 DNA replication complex GINS protein PSF2 Brachypodium distachyon
TI:15368 None
 
K3ZX30_SETIT
EnsemblPlants»
0.0
DNA replication complex GINS protein PSF2 Setaria italica
TI:4555 None
 
O77383_PLAF7
TubercuList»
0.0
PF3D7_0317400 DNA replication complex GINS protein, putative Plasmodium falciparum
TI:5833 None
 
PSF2_ASPFU
EnsemblFungi»
0.0
psf2 DNA replication complex GINS protein psf2 Aspergillus fumigatus
TI:746128 None
 
PSF2_CAEEL
WormBase»
0.5
psf-2 Probable DNA replication complex GINS
protein PSF2 (GINS complex subunit 2)		 Caenorhabditis elegans
TI:6239 None
 
PSF2_CANAL
EnsemblFungi»
0.0
PSF2 DNA replication complex GINS protein PSF2 Candida albicans
TI:5476 None
 
PSF2_CRYD1
EnsemblFungi»
0.0
PSF2 DNA replication complex GINS protein PSF2 Cryptococcus deneoformans
TI:40410 None
 
PSF2_DICDI
dictyBase»
1.5
gins2 Probable DNA replication complex GINS
protein PSF2 (GINS complex subunit 2)		 Dictyostelium discoideum
TI:44689 None
 
PSF2_EREGS
EnsemblFungi»
0.0
PSF2 DNA replication complex GINS protein PSF2 Eremothecium gossypii
TI:33169 None
 
PSF2_SCHPO
PomBase»
2.2
psf2 DNA replication complex GINS protein psf2 Schizosaccharomyces pombe
TI:4896 None
 
PSF2_YARLI
EnsemblFungi»
0.0
PSF2 DNA replication complex GINS protein PSF2 Yarrowia lipolytica
TI:4952 None
 
Q383N3_TRYB2
TubercuList»
0.0
Tb11.01.2230 Uncharacterized protein Trypanosoma brucei
TI:5691 None
 
Q4Q0Z5_LEIMA
TubercuList»
0.0
LMJF_36_4190 Uncharacterized protein Leishmania major
TI:5664 None
 
Q5TNY9_ANOGA
EnsemblMetazoa»
0.0
AgaP_AGAP010018 GINS complex subunit 2 Anopheles gambiae
TI:7165 None
 
Q5TXV1_ANOGA
EnsemblMetazoa»
0.0
3292521 DNA replication complex GINS protein PSF2 Anopheles gambiae
TI:7165 None
 
W1PJP5_AMBTC
euHCVdb»
0.0
AMTR_s00018p00208330 DNA replication complex GINS protein PSF2 Amborella trichopoda
TI:13333 None
 
W5LY21_LEPOC
Ensembl»
0.0
DNA replication complex GINS protein PSF2 Lepisosteus oculatus
TI:7918 None
 
A0A1D5PQM4_CHICK
Ensembl»
0.0
GINS2 DNA replication complex GINS protein PSF2 Gallus gallus
TI:9031 None
   
A0A1D5SWM0_WHEAT
EnsemblPlants»
0.0
LOC123144884 DNA replication complex GINS protein PSF2 Triticum aestivum
TI:4565 None
   
A0A1S4BN98_TOBAC
euHCVdb»
0.0
LOC107810098 DNA replication complex GINS protein PSF2 Nicotiana tabacum
TI:4097 None
   
A0A1S4CUG6_TOBAC
euHCVdb»
0.0
LOC107822712 DNA replication complex GINS protein PSF2 Nicotiana tabacum
TI:4097 None
   
A0A1U7ZHH4_NELNU
neXtProt»
0.0
LOC104594043 DNA replication complex GINS protein PSF2 Nelumbo nucifera
TI:4432 None
   
A0A1U8M692_GOSHI
euHCVdb»
0.0
LOC107934367 DNA replication complex GINS protein PSF2 Gossypium hirsutum
TI:3635 None
   
A0A287A814_PIG
Ensembl»
0.0
GINS2 DNA replication complex GINS protein PSF2 Sus scrofa
TI:9823 None
   
A0A2I4E4V4_JUGRE
neXtProt»
0.0
LOC108986308 DNA replication complex GINS protein PSF2 Juglans regia
TI:51240 None
   
A0A3B5Y6Y2_WHEAT
EnsemblPlants»
0.0
LOC123067312 DNA replication complex GINS protein PSF2 Triticum aestivum
TI:4565 None
   
A0A3Q7HGX1_SOLLC
EnsemblPlants»
0.0
DNA replication complex GINS protein PSF2 Solanum lycopersicum
TI:4081 None
   
A0A6I8MY39_ORNAN
Ensembl»
0.0
GINS2 DNA replication complex GINS protein PSF2 Ornithorhynchus anatinus
TI:9258 None
   
A0A7M7HGT9_STRPU
EnsemblMetazoa»
0.0
DNA replication complex GINS protein PSF2 Strongylocentrotus purpuratus
TI:7668 None
   
A0A804KZ71_MUSAM
EnsemblPlants»
0.0
DNA replication complex GINS protein PSF2 Musa acuminata
TI:4641 None
   
A0A8I3RRZ7_CANLF
Ensembl»
0.0
GINS2 DNA replication complex GINS protein PSF2 Canis lupus
TI:9612 None
   
A0A8I6WLL0_HORVV
EnsemblPlants»
0.0
LOC123449710 DNA replication complex GINS protein PSF2 Hordeum vulgare
TI:4513 None
   
A0A8V0YHG7_CHICK
Ensembl»
0.0
GINS complex subunit 2 Gallus gallus
TI:9031 None
   
A0A9R0ITY5_SPIOL
neXtProt»
0.0
LOC110794852 DNA replication complex GINS protein PSF2 Spinacia oleracea
TI:3562 None
   
A0AAA9SJV5_BOVIN
Ensembl»
0.0
GINS2 GINS complex subunit 2 Bos taurus
TI:9913 None
   
A0ABI7WGR4_FELCA
Ensembl»
0.0
GINS2 DNA replication complex GINS protein PSF2 Felis catus
TI:9685 None
   
D3ZSY6_RAT
RGD»
1.0
Gins2 DNA replication complex GINS protein PSF2 Rattus norvegicus
TI:10116 None
   
F6WT68_HORSE
Ensembl»
0.0
GINS2 DNA replication complex GINS protein PSF2 Equus caballus
TI:9796 None
   
F6Y4K0_MONDO
Ensembl»
0.0
GINS2 DNA replication complex GINS protein PSF2 Monodelphis domestica
TI:13616 None
   
F7BZU2_MACMU
Ensembl»
0.0
GINS2 DNA replication complex GINS protein PSF2 Macaca mulatta
TI:9544 None
   
H2M0K4_ORYLA
Ensembl»
0.0
GINS2 DNA replication complex GINS protein PSF2 Oryzias latipes
TI:8090 None
   
H9GAB4_ANOCA
Ensembl»
0.0
GINS2 DNA replication complex GINS protein PSF2 Anolis carolinensis
TI:28377 None
   
M1C604_SOLTU
EnsemblPlants»
0.0
LOC102583513 DNA replication complex GINS protein PSF2 Solanum tuberosum
TI:4113 None
   
M4CB75_BRACM
EnsemblPlants»
0.0
DNA replication complex GINS protein PSF2 Brassica campestris
TI:3711 None