Collated Gene Ontology terms

Biological process: diphthine synthase activity(2007, 2024, 2025) methyltransferase activity(2025) transferase activity(2024, 2025) diphthine methyl ester synthase activity(2005, 2024, 2025)

Molecular function: protein histidyl modification to diphthamide2005, 2008, 2013, 2014, 2022, 2024, 2025 methylation2025 regulation of cytoplasmic translation2009 positive regulation of translation2020 nervous system development2025 in utero embryonic development2025 cranial skeletal system development2025

Cellular component: cytosol2009, 2014, 2024, 2025 cytoplasm2014, 2017, 2018, 2025 nuclear lumen2017 ciliary plasm2017 plasma membrane2024 nucleus2009

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 3/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 7/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
DPH5_ARATH
TAIR»
0.5
At4g31790 Probable diphthine methyl ester synthase
(EC 2.1.1.314) (Diphthamide biosynthesis methyltransferase)		 Arabidopsis thaliana
TI:3702 None
 
Q17514_CAEEL
WormBase»
0.0
dph-5 diphthine methyl ester synthase (EC 2.1.1.314) Caenorhabditis elegans
TI:6239 None
 
A0A0R4IU56_DANRE
ZFIN»
0.0
dph5 diphthine methyl ester synthase (EC 2.1.1.314) Danio rerio
TI:7955 None
 
DPH5_DICDI
dictyBase»
1.0
dph5 Diphthine methyl ester synthase
(EC 2.1.1.314) (Diphthamide biosynthesis methyltransferase)		 Dictyostelium discoideum
TI:44689 None
 
Q8IN02_DROME
FlyBase»
1.8
Dph5 diphthine methyl ester synthase (EC 2.1.1.314) Drosophila melanogaster
TI:7227 None
 
F1P418_CHICK
Ensembl»
0.0
DPH5 diphthine methyl ester synthase (EC 2.1.1.314) Gallus gallus
TI:9031 None
   
DPH5_HUMAN
Ensembl»
3.4
DPH5 Diphthine methyl ester synthase
(EC 2.1.1.314) (Diphthamide biosynthesis methyltransferase)		 Homo sapiens
TI:9606 None
 
DPH5_MOUSE
Ensembl»
5.0
Dph5 Diphthine methyl ester synthase
(EC 2.1.1.314) (Diphthamide biosynthesis methyltransferase)		 Mus musculus
TI:10090 None
 
Q569A7_RAT
RGD»
1.0
Dph5 diphthine methyl ester synthase (EC 2.1.1.314) Rattus norvegicus
TI:10116 None
   
DPH5_YEAST
SGD»
3.2
DPH5 Diphthine methyl ester synthase
(EC 2.1.1.314) (Diphthamide biosynthesis methyltransferase)		 Saccharomyces cerevisiae
TI:4932 None
 
DPH5_SCHPO
PomBase»
2.5
dph5 Diphthine methyl ester synthase
(EC 2.1.1.314) (Diphthamide biosynthesis methyltransferase)		 Schizosaccharomyces pombe
TI:4896 None