Collated Gene Ontology terms

Biological process: SUMO transferase activity(2019, 2024) topological DNA co-entrapment activity(2022)

Molecular function: DNA repair2013, 2014, 2023, 2024 DNA recombination2024 DNA damage response2023, 2024 double-strand break repair via homologous recombination2018, 2020, 2022 regulation of telomere maintenance2018, 2020 protein sumoylation2018, 2020 chromatin looping2018, 2020 sorocarp development2015 response to UV2015 positive regulation of gene expression2015
meiotic cell cycle2024 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021

Cellular component: Smc5-Smc6 complex2004, 2012, 2013, 2014, 2017, 2018, 2020, 2024 nucleus2014, 2015, 2018, 2020, 2024 protein-containing complex2024 intracellular non-membrane-bounded organelle2024 chromosome, telomeric region2018, 2020, 2024 nucleoplasm2013, 2023, 2024 nuclear body2023, 2024 chromosome2024 cytoplasm2024 rDNA heterochromatin2015, 2024
pericentric heterochromatin2015, 2024 nucleolus2023, 2024 chromosome, subtelomeric region2015, 2024 CENP-A containing chromatin2015, 2024 membrane2024 euchromatin2019

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 1/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
NSE4A_ARATH
TAIR»
0.0
NSE4A Non-structural maintenance of chromosomes element 4
homolog A (Non-SMC element 4 homolog A)		 Arabidopsis thaliana
TI:3702 None
 
NSE4B_ARATH
TAIR»
0.0
NSE4B Non-structural maintenance of chromosomes element 4
homolog B (Non-SMC element 4 homolog B)		 Arabidopsis thaliana
TI:3702 None
 
Q9XTV3_CAEEL
WormBase»
0.5
nse-4 Non-structural maintenance of
chromosomes element 4		 Caenorhabditis elegans
TI:6239 None
 
A0A8M9QFD5_DANRE
CTD»
0.5
nsmce4a Non-structural maintenance of
chromosomes element 4		 Danio rerio
TI:7955 None
   
Q54T56_DICDI
dictyBase»
2.9
DDB_G0281991 Non-structural maintenance of
chromosomes element 4		 Dictyostelium discoideum
TI:44689 None
 
Q9VKV4_DROME
FlyBase»
1.0
Nse4 Non-structural maintenance of
chromosomes element 4		 Drosophila melanogaster
TI:7227 None
 
A0A8V0X2D1_CHICK
Ensembl»
0.0
NSMCE4A Non-structural maintenance of
chromosomes element 4		 Gallus gallus
TI:9031 None
   
EID3_HUMAN
Ensembl»
2.9
EID3 EP300-interacting inhibitor of differentiation 3 (EID-3) (E1A-like inhibitor of differentiation 3) (EID-1-like inhibitor of differentiation
3) (Non-structural maintenance of chromosomes element 4 homolog B) (NS4EB) (Non-SMC element 4 homolog B)		 Homo sapiens
TI:9606 None
 
NSE4A_HUMAN
Ensembl»
3.7
NSMCE4A Non-structural maintenance of chromosomes element 4 homolog
A (NS4EA) (Non-SMC element 4 homolog A)		 Homo sapiens
TI:9606 None
 
EID3_MOUSE
Ensembl»
0.0
Eid3 EP300-interacting inhibitor of differentiation 3 (EID-3) (EID-1-like inhibitor of differentiation 3) (Non-structural
maintenance of chromosomes element 4 homolog B) (NS4EB) (Non-SMC element 4 homolog B)		 Mus musculus
TI:10090 None
 
G3XA30_MOUSE
Ensembl»
0.0
Nsmce4a Non-structural maintenance of
chromosomes element 4		 Mus musculus
TI:10090 None
   
D3Z9K8_RAT
RGD»
1.0
Nsmce4a Non-structural maintenance of
chromosomes element 4		 Rattus norvegicus
TI:10116 None
   
EID3_RAT
RGD»
0.5
Eid3 EP300-interacting inhibitor of differentiation 3 (EID-3) (E1A-like inhibitor of differentiation 3) (EID-1-like inhibitor of differentiation
3) (Non-structural maintenance of chromosomes element 4 homolog B) (NS4EB) (Non-SMC element 4 homolog B)		 Rattus norvegicus
TI:10116 None
 
NSE4_YEAST
SGD»
4.5
NSE4 Non-structural maintenance of chromosome element
4 (Non-SMC element 4) (Protein QRI2)		 Saccharomyces cerevisiae
TI:4932 None
 
NSE4_SCHPO
PomBase»
2.1
nse4 Non-structural maintenance of chromosome element 4
(Non-SMC element 4) (DNA repair protein rad62)		 Schizosaccharomyces pombe
TI:4896 None