Unknome v3

Cluster UKP01335
UNCHARACTERIZED
Standard knownness: 4.5; Custom knownness: None; Num. species: 89; Orthology database: Panther19.0; Protein members: 157

Collated Gene Ontology terms

Biological process: SUMO transferase activity^{(2019, 2024)} topological DNA co-entrapment activity⁽²⁰²²⁾

Molecular function: DNA repair^{2013, 2014, 2023, 2024} DNA recombination²⁰²⁴ DNA damage response^{2023, 2024} double-strand break repair via homologous recombination^{2018, 2020, 2022} regulation of telomere maintenance^{2018, 2020} protein sumoylation^{2018, 2020} chromatin looping^{2018, 2020} sorocarp development²⁰¹⁵ response to UV²⁰¹⁵ positive regulation of gene expression²⁰¹⁵
meiotic cell cycle²⁰²⁴ maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)²⁰²¹

Cellular component: Smc5-Smc6 complex^{2004, 2012, 2013, 2014, 2017, 2018, 2020, 2024} nucleus^{2014, 2015, 2018, 2020, 2024} protein-containing complex²⁰²⁴ intracellular non-membrane-bounded organelle²⁰²⁴ chromosome, telomeric region^{2018, 2020, 2024} nucleoplasm^{2013, 2023, 2024} nuclear body^{2023, 2024} chromosome²⁰²⁴ cytoplasm²⁰²⁴ rDNA heterochromatin^{2015, 2024}
pericentric heterochromatin^{2015, 2024} nucleolus^{2023, 2024} chromosome, subtelomeric region^{2015, 2024} CENP-A containing chromatin^{2015, 2024} membrane²⁰²⁴ euchromatin²⁰¹⁹

Phylogenetic distribution

Chordates:	22/21
Echinoderms:	0/0
Hemichordates:	1/1
Annelids:	0/1
Molluscs:	0/0
Bryozoans:	0/0
Platyhelminthes:	0/0
Rotifers:	0/0
Nematodes:	3/3
Arthropods:	5/5
Tardigrades:	0/0
Placozoa:	1/1
Cnidaria:	1/1
Porifera:	0/0
Choanoflagellates+:	14/1
Dikarya:	0/14
Fungi (other):	0/1
Protozoa:	3/3
Excavates:	1/4
Harosa:	1/4
Hacrobia:	0/0
Plants:	37/39
Archea:	0/8
Bacteria:	0/35

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Protein sequences (FASTA format)

Knownness history

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Proteins

UniProt ID
Organism DB»

Species [Show all]

EID3_HUMAN
Ensembl»

2.9

EID3

EP300-interacting inhibitor of differentiation 3 (EID-3) (E1A-like inhibitor of differentiation 3) (EID-1-like inhibitor of differentiation
3) (Non-structural maintenance of chromosomes element 4 homolog B) (NS4EB) (Non-SMC element 4 homolog B)

Homo sapiens
TI:9606 None

EID3_RAT
RGD»

0.5

Eid3

Rattus norvegicus
TI:10116 None

EID3_MOUSE
Ensembl»

0.0

Eid3

EP300-interacting inhibitor of differentiation 3 (EID-3) (EID-1-like inhibitor of differentiation 3) (Non-structural
maintenance of chromosomes element 4 homolog B) (NS4EB) (Non-SMC element 4 homolog B)

Mus musculus
TI:10090 None

A0A8M9QFD5_DANRE
CTD»

0.5

nsmce4a