Collated Gene Ontology terms

Biological process: ribosome binding(2008, 2024) serine-type endopeptidase activity(2024) hydrolase activity(2024)

Molecular function: signal peptide processing2013, 2014, 2020, 2022, 2024 protein targeting to ER2013, 2017, 2024 virion assembly2019 viral protein processing2019 proteolysis2002

Cellular component: signal peptidase complex2002, 2014, 2019, 2020, 2022, 2023, 2024 endoplasmic reticulum membrane2002, 2004, 2009, 2013, 2020, 2022, 2024 endoplasmic reticulum2018, 2021, 2024 membrane2024

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 12/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 2/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 35/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
SPC1_YEAST
SGD»
4.8
SPC1 Signal peptidase complex subunit 1
(Microsomal signal peptidase subunit 1)		 Saccharomyces cerevisiae
TI:4932 None
 
SPCS1_HUMAN
Ensembl»
4.3
SPCS1 Signal peptidase complex subunit 1 (Microsomal signal
peptidase 12 kDa subunit) (SPase 12 kDa subunit)		 Homo sapiens
TI:9606 None
 
D3ZFK5_RAT
RGD»
3.0
Spcs1 Signal peptidase complex subunit 1
(Microsomal signal peptidase 12 kDa subunit)		 Rattus norvegicus
TI:10116 None
   
Q499B2_DANRE
ZFIN»
1.0
fa97f07 Signal peptidase complex subunit 1
(Microsomal signal peptidase 12 kDa subunit)		 Danio rerio
TI:7955 None
 
SPC1_SCHPO
PomBase»
1.0
spc1 Signal peptidase complex subunit 1 Schizosaccharomyces pombe
TI:4896 None
 
SPCS1_CAEEL
WormBase»
1.0
spcs-1 Signal peptidase complex subunit 1 (Microsomal signal
peptidase 12 kDa subunit) (SPase 12 kDa subunit)		 Caenorhabditis elegans
TI:6239 None
 
SPCS1_DICDI
dictyBase»
1.0
spcs1 Signal peptidase complex subunit 1 Dictyostelium discoideum
TI:44689 None
 
SPCS1_DROME
FlyBase»
1.0
Spase12 Signal peptidase complex subunit 1 (Microsomal signal
peptidase 12 kDa subunit) (SPase 12 kDa subunit)		 Drosophila melanogaster
TI:7227 None
 
SPCS1_MOUSE
Ensembl»
0.8
Spcs1 Signal peptidase complex subunit 1 (Microsomal signal
peptidase 12 kDa subunit) (SPase 12 kDa subunit)		 Mus musculus
TI:10090 None
 
A0A8V1A741_CHICK
Ensembl»
0.0
Signal peptidase complex subunit 1
(Microsomal signal peptidase 12 kDa subunit)		 Gallus gallus
TI:9031 None
   
Q84MC9_ARATH
TAIR»
0.0
At4g40042 At4g40042 (Microsomal signal peptidase
12 kDa subunit (SPC12))		 Arabidopsis thaliana
TI:3702 None
 
SPCS1_ARATH
TAIR»
0.0
At2g22425 Signal peptidase complex subunit 1 (Microsomal signal
peptidase 12 kDa subunit) (SPase 12 kDa subunit)		 Arabidopsis thaliana
TI:3702 None