Collated Gene Ontology terms

Biological process: cysteine-type deubiquitinase activity(2011, 2014, 2017, 2024) peptidase activity(2024) hydrolase activity(2024) nucleotide binding(2024)

Molecular function: protein deubiquitination2011, 2017, 2024 proteolysis2024 cranial skeletal system development2017, 2024 central nervous system morphogenesis2010

Cellular component: cytoplasm2024 plasma membrane2024 cytosol2016, 2024 membrane2014, 2024

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
W1PR61_AMBTC
EnsemblPlants»
0.0
AMTR_s00029p00222940 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Amborella trichopoda
TI:13333 None
 
G1KHD8_ANOCA
Ensembl»
0.0
JOSD1 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Anolis carolinensis
TI:28377 None
   
G1KLS4_ANOCA
Ensembl»
0.0
josd2 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Anolis carolinensis
TI:28377 None
   
Q7Q9I0_ANOGA
EnsemblMetazoa»
0.0
1274934 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Anopheles gambiae
TI:7165 None
 
JOSL_ARATH
TAIR»
0.0
At2g29640 Josephin-like protein (EC 3.4.19.12) Arabidopsis thaliana
TI:3702 None
 
F1ME39_BOVIN
Ensembl»
0.0
JOSD2 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Bos taurus
TI:9913 None
   
JOS1_BOVIN
CTD»
0.0
JOSD1 Josephin-1 (EC 3.4.19.12)
(Josephin domain-containing protein 1)		 Bos taurus
TI:9913 None
 
I1H757_BRADI
EnsemblPlants»
0.0
100846139 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Brachypodium distachyon
TI:15368 None
 
A0A9J7M729_BRAFL
CTD»
0.0
LOC118429589 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Branchiostoma floridae
TI:7739 None
   
A0A078I6E5_BRANA
EnsemblPlants»
0.0
BnaA05g12400D ubiquitinyl hydrolase 1 (EC 3.4.19.12) Brassica napus
TI:3708 None
 
A0A078IN55_BRANA
EnsemblPlants»
0.0
BnaA04g28510D ubiquitinyl hydrolase 1 (EC 3.4.19.12) Brassica napus
TI:3708 None
 
M4DPD0_BRACM
EnsemblPlants»
0.0
ubiquitinyl hydrolase 1 (EC 3.4.19.12) Brassica campestris
TI:3711 None
   
M4FFW6_BRACM
EnsemblPlants»
0.0
ubiquitinyl hydrolase 1 (EC 3.4.19.12) Brassica campestris
TI:3711 None
   
A8WMS1_CAEBR
WormBase»
0.0
josd-1 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Caenorhabditis briggsae
TI:6238 None
 
Q8IAA2_CAEEL
WormBase»
1.0
josd-1 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Caenorhabditis elegans
TI:6239 None
 
A0A8I3P0R2_CANLF
Ensembl»
0.0
JOSD2 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Canis lupus
TI:9612 None
   
A0A8I3S3G9_CANLF
Ensembl»
0.0
JOSD1 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Canis lupus
TI:9612 None
   
A0A2G3ALX5_CAPAN
EnsemblPlants»
0.0
T459_03111 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Capsicum annuum
TI:4072 None
 
A0A2K3DVG9_CHLRE
EnsemblPlants»
0.0
CHLRE_03g146707v5 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Chlamydomonas reinhardtii
TI:3055 None
 
F6VV86_CIOIN
Ensembl»
0.0
LOC101242901 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Ciona intestinalis
TI:7719 None
   
A0A067FHK4_CITSI
Ensembl»
0.0
CISIN_1g030121mg ubiquitinyl hydrolase 1 (EC 3.4.19.12) Citrus sinensis
TI:2711 None
 
A0A0A0KBN9_CUCSA
EnsemblPlants»
0.0
Csa_6G187930 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Cucumis sativus
TI:3659 None
 
A0A8M9PCZ4_DANRE
CTD»
2.6
josd2 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Danio rerio
TI:7955 None
   
Q08C38_DANRE
ZFIN»
1.8
zgc:153682 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Danio rerio
TI:7955 None
 
E9GLH3_DAPPU
EnsemblMetazoa»
0.0
EOG090X0HOM ubiquitinyl hydrolase 1 (EC 3.4.19.12) Daphnia pulex
TI:6669 None
 
F0ZVQ6_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_89426 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Dictyostelium purpureum
TI:5786 None
 
Q55DI9_DICDI
dictyBase»
1.0
DDB_G0269646 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Dictyostelium discoideum
TI:44689 None
 
JOSL_DROME
FlyBase»
1.5
Josd Josephin-like protein (EC 3.4.19.12) Drosophila melanogaster
TI:7227 None
 
A0A3Q2HHJ2_HORSE
Ensembl»
0.0
JOSD2 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Equus caballus
TI:9796 None
   
A0A3Q2HQB8_HORSE
Ensembl»
0.0
ubiquitinyl hydrolase 1 (EC 3.4.19.12) Equus caballus
TI:9796 None
   
A0A022S024_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a017948mg ubiquitinyl hydrolase 1 (EC 3.4.19.12) Erythranthe guttata
TI:4155 None
 
A0A2I2UCD1_FELCA
Ensembl»
0.0
JOSD2 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Felis catus
TI:9685 None
 
A0A2I2UM21_FELCA
Ensembl»
0.0
JOSD1 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Felis catus
TI:9685 None
 
A0A1D5P643_CHICK
Ensembl»
1.0
JOSD1 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Gallus gallus
TI:9031 None
   
K7KA59_SOYBN
EnsemblPlants»
0.0
100800726 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Glycine max
TI:3847 None
 
K7M807_SOYBN
EnsemblPlants»
0.0
100814201 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Glycine max
TI:3847 None
 
G3QI57_GORGO
Ensembl»
0.0
JOSD1 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Gorilla gorilla
TI:9593 None
 
G3RV28_GORGO
Ensembl»
0.0
JOSD2 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Gorilla gorilla
TI:9593 None
 
A0A1U8JLE6_GOSHI
Ensembl»
0.0
LOC107906607 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Gossypium hirsutum
TI:3635 None
   
A0A1U8PHK7_GOSHI
Ensembl»
0.0
LOC107959176 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Gossypium hirsutum
TI:3635 None
   
A0A9K3DVH5_HELAN
EnsemblPlants»
0.0
HanXRQr2_Chr16g0766971 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Helianthus annuus
TI:4232 None
 
T1FYS9_HELRO
EnsemblMetazoa»
0.0
20213977 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Helobdella robusta
TI:6412 None
 
JOS1_HUMAN
Ensembl»
2.8
JOSD1 Josephin-1 (EC 3.4.19.12)
(Josephin domain-containing protein 1)		 Homo sapiens
TI:9606 None
 
JOS2_HUMAN
Ensembl»
4.4
JOSD2 Josephin-2 (EC 3.4.19.12)
(Josephin domain-containing protein 2)		 Homo sapiens
TI:9606 None
 
F2DWP6_HORVV
EnsemblPlants»
0.0
ubiquitinyl hydrolase 1 (EC 3.4.19.12) Hordeum vulgare
TI:4513 None
 
B7P7H9_IXOSC
EnsemblMetazoa»
0.0
8025771 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Ixodes scapularis
TI:6945 None
 
A0A2I4DE76_JUGRE
EnsemblPlants»
0.0
LOC108979256 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Juglans regia
TI:51240 None
 
A0A1Y1HLC5_KLENI
EnsemblPlants»
0.0
KFL_000180550 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Klebsormidium nitens
TI:105231 None
 
W5N0M2_LEPOC
Ensembl»
0.0
ubiquitinyl hydrolase 1 (EC 3.4.19.12) Lepisosteus oculatus
TI:7918 None
 
G7N3V7_MACMU
Ensembl»
0.0
JOSD1 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Macaca mulatta
TI:9544 None
 
H9FN04_MACMU
Ensembl»
0.0
JOSD2 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Macaca mulatta
TI:9544 None
 
A0A2C9WD59_MANES
EnsemblPlants»
0.0
MANES_02G121500 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Manihot esculenta
TI:3983 None
 
A0A2R6XAG6_MARPO
EnsemblPlants»
0.0
MARPO_0026s0005 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Marchantia polymorpha
TI:3197 None
 
G7K6B3_MEDTR
EnsemblPlants»
0.0
11413475 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Medicago truncatula
TI:3880 None
 
F6RDU7_MONDO
Ensembl»
0.0
JOSD1 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Monodelphis domestica
TI:13616 None
   
A9URE1_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_31347 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Monosiga brevicollis
TI:81824 None
 
JOS1_MOUSE
Ensembl»
0.0
Josd1 Josephin-1 (EC 3.4.19.12)
(Josephin domain-containing protein 1)		 Mus musculus
TI:10090 None
 
JOS2_MOUSE
Ensembl»
0.0
Josd2 Josephin-2 (EC 3.4.19.12)
(Josephin domain-containing protein 2)		 Mus musculus
TI:10090 None
 
A0A804JAK5_MUSAM
EnsemblPlants»
0.0
ubiquitinyl hydrolase 1 (EC 3.4.19.12) Musa acuminata
TI:4641 None
   
A0A1U7ZWI8_NELNU
EnsemblBacteria»
0.0
LOC104596979 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Nelumbo nucifera
TI:4432 None
   
A7SDY8_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g114706 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Nematostella vectensis
TI:45351 None
 
A0A1S3WZJ8_TOBAC
EnsemblFungi»
0.0
LOC107759602 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Nicotiana tabacum
TI:4097 None
   
A0A1S3YDT0_TOBAC
EnsemblFungi»
0.0
LOC107775198 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Nicotiana tabacum
TI:4097 None
   
A0A6I8NUT6_ORNAN
Ensembl»
0.0
JOSD2 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Ornithorhynchus anatinus
TI:9258 None
   
F6T9U8_ORNAN
Ensembl»
0.0
JOSD1 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Ornithorhynchus anatinus
TI:9258 None
   
Q10NM7_ORYSJ
EnsemblPlants»
0.0
LOC_Os03g15850 Os03g0265200 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Oryza sativa
TI:4530 None
 
A0A3B3H4W8_ORYLA
Ensembl»
0.0
josd1 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Oryzias latipes
TI:8090 None
   
H2M703_ORYLA
Ensembl»
0.0
josd2 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Oryzias latipes
TI:8090 None
   
H2QLP0_PANTR
Ensembl»
0.0
JOSD1 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Pan troglodytes
TI:9598 None
 
K7CSV4_PANTR
Ensembl»
0.0
JOSD2 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Pan troglodytes
TI:9598 None
 
A0BSG9_PARTE
EnsemblProtists»
0.0
GSPATT00031718001 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Paramecium tetraurelia
TI:5888 None
 
A0CQD9_PARTE
EnsemblProtists»
0.0
GSPATT00009354001 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Paramecium tetraurelia
TI:5888 None
 
A0DAK4_PARTE
EnsemblProtists»
0.0
GSPATT00014978001 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Paramecium tetraurelia
TI:5888 None
 
A0A2K1JM96_PHYPA
EnsemblPlants»
0.0
PHYPA_017489 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Physcomitrium patens
TI:3218 None
 
H3GTW7_PHYRM
EnsemblProtists»
0.0
ubiquitinyl hydrolase 1 (EC 3.4.19.12) Phytophthora ramorum
TI:164328 None
 
Q8IIP4_PLAF7
EnsemblProtists»
0.0
PF3D7_1111900 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Plasmodium falciparum
TI:5833 None
 
A0A2K2C3A1_POPTR
EnsemblPlants»
0.0
POPTR_001G249400 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Populus trichocarpa
TI:3694 None
 
B9HP66_POPTR
EnsemblPlants»
0.0
POPTR_009G043400 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Populus trichocarpa
TI:3694 None
 
A0A8R1V2P2_PRIPA
EnsemblMetazoa»
0.0
WBGene00304633 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Pristionchus pacificus
TI:54126 None
   
M5WK40_PRUPE
EnsemblPlants»
0.0
PRUPE_6G060500 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Prunus persica
TI:3760 None
 
A0A0G2K133_RAT
RGD»
1.0
AABR07006871.1 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Rattus norvegicus
TI:10116 None
   
D4AD44_RAT
RGD»
2.0
Josd2 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Rattus norvegicus
TI:10116 None
   
JOS1_RAT
RGD»
1.0
Josd1 Josephin-1 (EC 3.4.19.12)
(Josephin domain-containing protein 1)		 Rattus norvegicus
TI:10116 None
 
B9SHY7_RICCO
EnsemblBacteria»
0.0
RCOM_0611500 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Ricinus communis
TI:3988 None
 
D8R3E3_SELML
EnsemblPlants»
0.0
SELMODRAFT_84199 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Selaginella moellendorffii
TI:88036 None
 
D8SI32_SELML
EnsemblPlants»
0.0
SELMODRAFT_117430 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Selaginella moellendorffii
TI:88036 None
 
K4AFD6_SETIT
EnsemblPlants»
0.0
101779065 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Setaria italica
TI:4555 None
 
A0A3Q7I2G7_SOLLC
EnsemblPlants»
0.0
101267342 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Solanum lycopersicum
TI:4081 None
   
M1BVG4_SOLTU
EnsemblPlants»
0.0
ubiquitinyl hydrolase 1 (EC 3.4.19.12) Solanum tuberosum
TI:4113 None
   
C5WQ53_SORBI
EnsemblPlants»
0.0
SORBI_3001G427200 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Sorghum bicolor
TI:4558 None
 
A0A7M7NS88_STRPU
EnsemblMetazoa»
0.0
ubiquitinyl hydrolase 1 (EC 3.4.19.12) Strongylocentrotus purpuratus
TI:7668 None
   
A0A287A7C8_PIG
Ensembl»
0.0
JOSD2 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Sus scrofa
TI:9823 None
   
A0A4X1VR79_PIG
Ensembl»
0.0
JOSD1 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Sus scrofa
TI:9823 None
 
B8C3F4_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_5624 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Thalassiosira pseudonana
TI:35128 None
 
A0A061GWC4_THECC
EnsemblPlants»
0.0
TCM_041657 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Theobroma cacao
TI:3641 None
 
D6X2A7_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_12435 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Tribolium castaneum
TI:7070 None
 
B3RPS8_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_21661 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Trichoplax adhaerens
TI:10228 None
 
A0A3B6HU20_WHEAT
EnsemblPlants»
0.0
CFC21_051716 CFC21_051717 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Triticum aestivum
TI:4565 None
 
W5EJX2_WHEAT
EnsemblPlants»
0.0
CFC21_032826 CFC21_058113 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Triticum aestivum
TI:4565 None
 
D7SK18_VITVI
EnsemblPlants»
0.0
VIT_06s0004g06160 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Vitis vinifera
TI:29760 None
 
A0A1L8GH08_XENLA
Xenbase»
0.0
josd1.S Josephin-1 (EC 3.4.19.12)
(Josephin domain-containing protein 1)		 Xenopus laevis
TI:8355 None
   
B2GUF1_XENTR
Xenbase»
0.0
josd1 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Xenopus tropicalis
TI:8364 None
 
Q28GQ6_XENTR
Xenbase»
0.0
josd2 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Xenopus tropicalis
TI:8364 None
 
Q2TAT8_XENLA
Xenbase»
0.0
josd1.L Josephin-1 (EC 3.4.19.12)
(Josephin domain-containing protein 1)		 Xenopus laevis
TI:8355 None
 
Q5EAV9_XENLA
Xenbase»
0.0
josd2.L ubiquitinyl hydrolase 1 (EC 3.4.19.12) Xenopus laevis
TI:8355 None
 
A0A804LHL6_MAIZE
EnsemblPlants»
0.0
100282423 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Zea mays
TI:4577 None
   
A0A0K9PR60_ZOSMR
EnsemblPlants»
0.0
ZOSMA_195G00060 ubiquitinyl hydrolase 1 (EC 3.4.19.12) Zostera marina
TI:29655 None