Collated Gene Ontology terms

Biological process: nuclease activity(2025) hydrolase activity(2025)

Molecular function: mRNA processing2013, 2025 RNA splicing2005, 2025 mRNA splicing, via spliceosome2010, 2019, 2025 dendrite development2025 spindle assembly2024 protein catabolic process2024 ovarian follicle development2024 oogenesis2024 oocyte development2024 learning or memory2025
dentate gyrus development2025 dendritic spine organization2025 dendrite morphogenesis2025 alternative mRNA splicing, via spliceosome2024 mRNA cis splicing, via spliceosome2024 innate immune response2025 immune system process2025 defense response to fungus2007 defense response to bacterium2007 defense response2025 RNA splicing, via transesterification reactions2005

Cellular component: Prp19 complex2012, 2014, 2024, 2025 nucleus2007, 2009, 2018, 2019, 2025 spliceosomal complex2006, 2014, 2025 catalytic step 2 spliceosome2010, 2017, 2025 U2-type catalytic step 2 spliceosome2018, 2019, 2025 DNA replication factor A complex2014, 2025 nuclear speck2024, 2025 precatalytic spliceosome2010, 2025 post-mRNA release spliceosomal complex2016, 2025 nucleolus2021, 2025
post-spliceosomal complex2025 U2-type catalytic step 1 spliceosome2025 nucleoplasm2014 cytosol2019 centrosome2025

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 12/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
SPF27_ARATH
TAIR»
1.6
MOS4 Pre-mRNA-splicing factor SPF27 homolog (Modifier of
SNC1 member 4) (Protein BCAS2 homolog)		 Arabidopsis thaliana
TI:3702 None
 
A0A679L8Q6_CAEEL
WormBase»
0.0
CELE_T12A2.21 T12A2.21 Uncharacterized protein Caenorhabditis elegans
TI:6239 None
 
Q22417_CAEEL
WormBase»
0.0
bcas-2 Pre-mRNA-splicing factor SPF27 Caenorhabditis elegans
TI:6239 None
 
SPF27_DANRE
ZFIN»
0.5
bcas2 Pre-mRNA-splicing factor SPF27
(Protein BCAS2 homolog)		 Danio rerio
TI:7955 None
 
SPF27_DICDI
dictyBase»
0.0
spf27 Pre-mRNA-splicing factor spf27 Dictyostelium discoideum
TI:44689 None
 
Q9VAY6_DROME
FlyBase»
1.8
BCAS2 Pre-mRNA-splicing factor SPF27 Drosophila melanogaster
TI:7227 None
 
A0A8V1A7U7_CHICK
Ensembl»
0.0
BCAS2 Pre-mRNA-splicing factor SPF27 Gallus gallus
TI:9031 None
   
SPF27_HUMAN
Ensembl»
3.2
BCAS2 Pre-mRNA-splicing factor SPF27 (Breast carcinoma-amplified sequence 2) (DNA amplified
in mammary carcinoma 1 protein) (Spliceosome-associated protein SPF 27)		 Homo sapiens
TI:9606 None
 
SPF27_MOUSE
Ensembl»
11.2
Bcas2 Pre-mRNA-splicing factor SPF27 (Breast carcinoma-amplified sequence 2
homolog) (DNA amplified in mammary carcinoma 1 protein)		 Mus musculus
TI:10090 None
 
B5DFM8_RAT
RGD»
6.0
Bcas2 Pre-mRNA-splicing factor SPF27 Rattus norvegicus
TI:10116 None
   
SPF27_SCHPO
PomBase»
0.8
cwf7 Pre-mRNA-splicing factor cwf7 (Complexed with
cdc5 protein 7) (Splicing factor 27)		 Schizosaccharomyces pombe
TI:4896 None