Collated Gene Ontology terms

Biological process: oxidoreductase activity(2025) FAD binding(2025) monooxygenase activity(2014, 2025) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen(2007, 2025) flavin adenine dinucleotide binding(2025) 4-hydroxy-3-all-trans-polyprenylbenzoate oxygenase activity(2023, 2025) 2-methoxy-6-polyprenolphenol 4-hydroxylase activity(2025) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(2015, 2025) 2-octaprenyl-6-methoxyphenol hydroxylase activity(2007, 2014, 2018, 2025) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(2024, 2025)
2-polyprenylphenol 6-hydroxylase activity2013, 2018, 2025 3-demethoxyubiquinol 3-hydroxylase activity2008, 2018, 2025 zinc ion binding2025 kynurenine 3-monooxygenase activity2025 hydrolase activity2025 catalytic activity2025 DNA-binding transcription factor activity, RNA polymerase II-specific2025 DNA binding2025

Molecular function: ubiquinone biosynthetic process2006, 2007, 2013, 2016, 2017, 2024, 2025 xanthophyll biosynthetic process2025 carotene biosynthetic process2025 response to oxidative stress2009 response to light stimulus2010 regulation of transcription by RNA polymerase II2025 regulation of DNA-templated transcription2025 DNA-templated transcription2025

Cellular component: mitochondrion2009, 2010, 2014, 2016, 2017, 2018, 2024, 2025 mitochondrial inner membrane2012, 2024, 2025 extrinsic component of mitochondrial inner membrane2024, 2025 ubiquinone biosynthesis complex2019, 2024, 2025 cell projection2025 Golgi apparatus2025 cytoplasm2025 kinetoplast2018, 2025 mitochondrial membrane2009 NADH dehydrogenase complex2017

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 13/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 0/8 
Bacteria: 11/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
COQ6_MOUSE
Ensembl»
6.2
Coq6 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial (EC 1.14.15.45)
(2-methoxy-6-polyprenolphenol 4-hydroxylase) (EC 1.14.15.46) (Coenzyme Q10 monooxygenase 6)		 Mus musculus
TI:10090 None
 
COQ6_RAT
RGD»
4.5
Coq6 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial (EC 1.14.15.45)
(2-methoxy-6-polyprenolphenol 4-hydroxylase) (EC 1.14.15.46) (Coenzyme Q10 monooxygenase 6)		 Rattus norvegicus
TI:10116 None
 
COQ6_YEAST
SGD»
4.5
COQ6 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial (EC 1.14.15.45)
(2-methoxy-6-polyprenolphenol 4-hydroxylase) (EC 1.14.15.46) (Ubiquinone C4-deaminase) (EC 3.5.-.-)		 Saccharomyces cerevisiae
TI:4932 None
 
UBIH_ECOLI
EnsemblBacteria»
4.2
ubiH 2-octaprenyl-6-methoxyphenol hydroxylase
(EC 1.14.13.-)		 Escherichia coli
TI:562 None
 
COQ6_HUMAN
Ensembl»
4.0
COQ6 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial (EC 1.14.15.45)
(2-methoxy-6-polyprenolphenol 4-hydroxylase) (EC 1.14.15.46) (Coenzyme Q10 monooxygenase 6)		 Homo sapiens
TI:9606 None
 
COQ6_DROME
FlyBase»
3.3
Coq6 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial
(EC 1.14.15.45) (2-methoxy-6-polyprenolphenol 4-hydroxylase) (EC 1.14.15.46)		 Drosophila melanogaster
TI:7227 None
 
UBIF_ECOLI
EnsemblBacteria»
3.1
ubiF 3-demethoxyubiquinol 3-hydroxylase (EC
1.14.99.60) (2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase)		 Escherichia coli
TI:562 None
 
UBII_ECOLI
EnsemblBacteria»
2.6
ubiI 2-octaprenylphenol hydroxylase (EC
1.14.13.240) (2-polyprenylphenol 6-hydroxylase)		 Escherichia coli
TI:562 None
 
COQ6_DANRE
ZFIN»
2.5
coq6 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial (EC 1.14.15.45)
(2-methoxy-6-polyprenolphenol 4-hydroxylase) (EC 1.14.15.46) (Coenzyme Q10 monooxygenase 6)		 Danio rerio
TI:7955 None
 
COQ6_CAEEL
WormBase»
1.8
coq-6 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial
(EC 1.14.15.45) (2-methoxy-6-polyprenolphenol 4-hydroxylase) (EC 1.14.15.46)		 Caenorhabditis elegans
TI:6239 None
 
COQ6_SCHPO
PomBase»
1.8
coq6 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial
(EC 1.14.15.45) (2-methoxy-6-polyprenolphenol 4-hydroxylase) (EC 1.14.15.46)		 Schizosaccharomyces pombe
TI:4896 None
 
F4J6I6_ARATH
TAIR»
1.5
COQ6 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial
(EC 1.14.15.45) (2-methoxy-6-polyprenolphenol 4-hydroxylase) (EC 1.14.15.46)		 Arabidopsis thaliana
TI:3702 None
 
COQ6_DICDI
dictyBase»
1.0
coq6 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial
(EC 1.14.15.45) (2-methoxy-6-polyprenolphenol 4-hydroxylase) (EC 1.14.15.46)		 Dictyostelium discoideum
TI:44689 None
 
A0A8V0XQX2_CHICK
Ensembl»
0.0
COQ6 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial (EC 1.14.15.45)
(2-methoxy-6-polyprenolphenol 4-hydroxylase) (Coenzyme Q10 monooxygenase 6) (EC 1.14.15.46)		 Gallus gallus
TI:9031 None