Collated Gene Ontology terms

Biological process: S-methyl-5-thioribose-1-phosphate isomerase activity(2013, 2017, 2025) isomerase activity(2025) translation initiation factor activity(2014, 2025) identical protein binding(2025) ribose 1,5-bisphosphate isomerase activity(2025) intramolecular oxidoreductase activity, interconverting aldoses and ketoses(2025) hydrolase activity(2025) transferase activity(2025) thiolester hydrolase activity(2025) nuclease activity(2025)
hydrolase activity, acting on ester bonds2025 GTP binding2014

Molecular function: L-methionine salvage from methylthioadenosine2013, 2017, 2025 amino acid biosynthetic process2025 methionine biosynthetic process2025 translational initiation2014, 2025 pentose catabolic process2025 carbohydrate metabolic process2025

Cellular component: nucleus2005, 2018, 2025 cytoplasm2018, 2025 cytoplasmic stress granule2022, 2025 nucleoplasm2024, 2025 cytosol2009, 2013, 2025 plasmodesma2021 mitochondrion2019 fibrillar center2025 extracellular region2018 eukaryotic translation initiation factor 2B complex2014
cell projection2025

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 35/39 
Archea: 8/8 
Bacteria: 18/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
MTNA_HUMAN
Ensembl»
3.6
MRI1 Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (Mediator of RhoA-dependent
invasion) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)		 Homo sapiens
TI:9606 None
 
MTNA_MOUSE
Ensembl»
1.5
Mri1 Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate
isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)		 Mus musculus
TI:10090 None
 
MTNA_ARATH
TAIR»
1.0
At2g05830 Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate
isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)		 Arabidopsis thaliana
TI:3702 None
 
MTNA_YEAST
SGD»
2.6
MRI1 Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate
isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)		 Saccharomyces cerevisiae
TI:4932 None
 
A0A8V0XJU7_CHICK
Ensembl»
1.0
MRI1 Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate
isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)		 Gallus gallus
TI:9031 None
   
MTNA_RAT
RGD»
1.5
Mri1 Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate
isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)		 Rattus norvegicus
TI:10116 None
 
MTNA_SCHPO
PomBase»
1.0
mri1 Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate
isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)		 Schizosaccharomyces pombe
TI:4896 None
 
Q54R90_DICDI
dictyBase»
1.0
DDB_G0283309 Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate
isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)		 Dictyostelium discoideum
TI:44689 None
 
MTNA_CAEEL
WormBase»
1.0
C01G10.9 Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate
isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)		 Caenorhabditis elegans
TI:6239 None
 
MTNA_DANRE
ZFIN»
1.0
mri1 Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate
isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)		 Danio rerio
TI:7955 None
 
MTNA_DROME
FlyBase»
1.0
Mri1 Methylthioribose-1-phosphate isomerase 1 (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23)
(S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)		 Drosophila melanogaster
TI:7227 None