Collated Gene Ontology terms

Biological process: proline-tRNA ligase activity(2005, 2007, 2016, 2017, 2019, 2025) nucleotide binding(2025) ligase activity(2025) aminoacyl-tRNA ligase activity(2025) ATP binding(2025) aminoacyl-tRNA deacylase activity(2025) catalytic activity, acting on a tRNA(2025) transferase activity(2025) catalytic activity, acting on a protein(2025) structural constituent of ribosome(2001, 2016)
RNA binding2014, 2025 proton transmembrane transporter activity2025 Ala-tRNA(Pro) deacylase activity2010

Molecular function: prolyl-tRNA aminoacylation2005, 2016, 2017, 2021, 2025 tRNA aminoacylation for protein translation2025 translation2001, 2025 aminoacyl-tRNA metabolism involved in translational fidelity2021, 2025 mitochondrial translation2009, 2016, 2025 regulatory ncRNA-mediated gene silencing2025 regulation of translation2025 proton transmembrane transport2025 proton motive force-driven ATP synthesis2025 monoatomic ion transport2025
mitochondrion organization2001

Cellular component: mitochondrion2009, 2016, 2018, 2024, 2025 cytoplasm2025 cytosol2008, 2014, 2017, 2025 ribosome2025 ribonucleoprotein complex2025 mitochondrial matrix2018, 2025 mitochondrial large ribosomal subunit2001, 2016, 2018, 2025 mitochondrial inner membrane2014, 2025 proton-transporting ATP synthase complex2025 plasma membrane2010
peptidoglycan-based cell wall2010 mitochondrial ribosome2002

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 12/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 30/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A8I6A9P7_RAT
RGD»
0.0
Mrpl39 Mitochondrial ribosomal protein L39 Rattus norvegicus
TI:10116 None
   
A0A8V0Y7X0_CHICK
Ensembl»
0.0
MRPL39 Large ribosomal subunit protein mL39
(39S ribosomal protein L39, mitochondrial)		 Gallus gallus
TI:9031 None
   
A0A8V0ZXU5_CHICK
Ensembl»
1.0
TTC4 Probable proline--tRNA ligase, mitochondrial
(EC 6.1.1.15) (Prolyl-tRNA synthetase)		 Gallus gallus
TI:9031 None
   
O45869_CAEEL
WormBase»
1.0
pars-2 Probable proline--tRNA ligase, mitochondrial
(EC 6.1.1.15) (Prolyl-tRNA synthetase)		 Caenorhabditis elegans
TI:6239 None
 
Q6P0C4_DANRE
ZFIN»
1.0
pars2 Probable proline--tRNA ligase, mitochondrial
(EC 6.1.1.15) (Prolyl-tRNA synthetase)		 Danio rerio
TI:7955 None
 
Q75JK9_DICDI
dictyBase»
2.0
mproS proline--tRNA ligase (EC
6.1.1.15) (Prolyl-tRNA synthetase)		 Dictyostelium discoideum
TI:44689 None
 
Q7T3F9_DANRE
ZFIN»
0.0
mrpl39 Large ribosomal subunit protein mL39
(39S ribosomal protein L39, mitochondrial)		 Danio rerio
TI:7955 None
 
Q9VZY9_DROME
FlyBase»
2.8
ProRS-m Probable proline--tRNA ligase, mitochondrial
(EC 6.1.1.15) (Prolyl-tRNA synthetase)		 Drosophila melanogaster
TI:7227 None
 
RM39_DROME
FlyBase»
1.8
mRpL39 Large ribosomal subunit protein mL39 (39S
ribosomal protein L39, mitochondrial) (MRP-L39) (MRP-L5)		 Drosophila melanogaster
TI:7227 None
 
RM39_HUMAN
Ensembl»
1.1
MRPL39 Large ribosomal subunit protein mL39 (39S ribosomal protein L39,
mitochondrial) (L39mt) (MRP-L39) (39S ribosomal protein L5, mitochondrial) (L5mt) (MRP-L5)		 Homo sapiens
TI:9606 None
 
RM39_MOUSE
Ensembl»
2.5
Mrpl39 Large ribosomal subunit protein mL39 (39S
ribosomal protein L39, mitochondrial) (L39mt) (MRP-L39)		 Mus musculus
TI:10090 None
 
SYPM_HUMAN
Ensembl»
1.0
PARS2 Probable proline--tRNA ligase, mitochondrial (EC 6.1.1.15)
(Prolyl-tRNA synthetase) (ProRS) (Prolyl-tRNA synthetase 2, mitochondrial)		 Homo sapiens
TI:9606 None
 
SYPM_MOUSE
Ensembl»
1.0
Pars2 Probable proline--tRNA ligase, mitochondrial
(EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)		 Mus musculus
TI:10090 None
 
SYPM_RAT
RGD»
1.0
Pars2 Probable proline--tRNA ligase, mitochondrial
(EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)		 Rattus norvegicus
TI:10116 None
 
SYPM_SCHPO
PomBase»
1.6
SPBC24C6.03 Probable proline--tRNA ligase, mitochondrial
(EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)		 Schizosaccharomyces pombe
TI:4896 None
 
SYPM_YEAST
SGD»
1.5
AIM10 Probable proline--tRNA ligase, mitochondrial (EC 6.1.1.15) (Altered inheritance
rate of mitochondria protein 10) (Prolyl-tRNA synthetase) (ProRS)		 Saccharomyces cerevisiae
TI:4932 None
 
SYP_ECOLI
EnsemblBacteria»
4.2
proS Proline--tRNA ligase (EC 6.1.1.15) (Global
RNA synthesis factor) (Prolyl-tRNA synthetase) (ProRS)		 Escherichia coli
TI:562 None