Collated Gene Ontology terms

Biological process: L-threonine 3-dehydrogenase activity(2017, 2019, 2024) identical protein binding(2017, 2024) oxidoreductase activity(2024) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(2024) isomerase activity(2024) UDP-glucose 4-epimerase activity(2024)

Molecular function: threonine catabolic process2017, 2019, 2024 steroid biosynthetic process2024 L-threonine catabolic process to glycine2024 innate immune response2014

Cellular component: mitochondrion2009, 2014, 2017, 2024 membrane2024 mitochondrial inner membrane2015

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 2/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 2/39 
Archea: 1/8 
Bacteria: 5/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
H9GH04_ANOCA
Ensembl»
0.0
LOC100559095 NAD-dependent epimerase/dehydratase
domain-containing protein		 Anolis carolinensis
TI:28377 None
   
Q7PZJ8_ANOGA
EnsemblMetazoa»
0.0
1280721 AGAP011948-PA Anopheles gambiae
TI:7165 None
 
Q81I04_BACCR
EnsemblBacteria»
0.0
BC_0622 L-threonine 3-dehydrogenase (EC 1.1.1.103) Bacillus cereus
TI:1396 None
 
Q8A804_BACTN
EnsemblBacteria»
0.0
BT_1370 NAD dependent
nucleotide-diphosphate-sugar epimerase		 Bacteroides thetaiotaomicron
TI:818 None
 
TDH_BOVIN
Ensembl»
0.0
TDH L-threonine 3-dehydrogenase,
mitochondrial (EC 1.1.1.103)		 Bos taurus
TI:9913 None
 
A0A9J7KC24_BRAFL
CTD»
0.0
LOC118408277 L-threonine 3-dehydrogenase, mitochondrial-like Branchiostoma floridae
TI:7739 None 		     
A0A9J7LGW0_BRAFL
CTD»
0.0
LOC118419237 L-threonine 3-dehydrogenase, mitochondrial-like Branchiostoma floridae
TI:7739 None 		     
A8X972_CAEBR
WormBase»
0.0
CBG09393 CBG_09393 Protein CBG09393 Caenorhabditis briggsae
TI:6238 None
 
Q22945_CAEEL
WormBase»
1.5
CELE_F08F3.4 F08F3.4 NAD-dependent epimerase/dehydratase
domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
A0A8I3P4Y1_CANLF
Ensembl»
0.0
TDH L-threonine dehydrogenase Canis lupus
TI:9612 None
   
F6UCU4_CIOIN
Ensembl»
0.0
NAD-dependent epimerase/dehydratase
domain-containing protein		 Ciona intestinalis
TI:7719 None
 
A5PLC4_DANRE
ZFIN»
1.0
tdh2 Uncharacterized protein
LOC556781 (Zgc:165525 protein)		 Danio rerio
TI:7955 None
 
Q6P3J8_DANRE
ZFIN»
1.0
wu:fc11b08 L-threonine 3-dehydrogenase, mitochondrial (EC 1.1.1.103) (L-threonine
3-dehydrogenase, mitochondrial isoform X1) (L-threonine dehydrogenase)		 Danio rerio
TI:7955 None
 
E9HKX9_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_63809 NAD-dependent epimerase/dehydratase
domain-containing protein		 Daphnia pulex
TI:6669 None
 
B8DZ37_DICTD
EnsemblBacteria»
0.0
Dtur_0351 NAD-dependent epimerase/dehydratase Dictyoglomus turgidum
TI:513050 None
 
Q9VPE8_DROME
FlyBase»
1.0
Tdh GH18546p Drosophila melanogaster
TI:7227 None
 
M3VZJ4_FELCA
Ensembl»
0.0
TDH L-threonine dehydrogenase Felis catus
TI:9685 None 		 
 
A0A8V0Y8P2_CHICK
Ensembl»
0.0
TDH NAD-dependent epimerase/dehydratase
domain-containing protein		 Gallus gallus
TI:9031 None 		     
G3S6Q2_GORGO
Ensembl»
0.0
NAD-dependent epimerase/dehydratase
domain-containing protein		 Gorilla gorilla
TI:9593 None
 
T1EEN9_HELRO
EnsemblMetazoa»
0.0
20195041 NAD-dependent epimerase/dehydratase
domain-containing protein		 Helobdella robusta
TI:6412 None
 
TDH_HUMAN
AG»
0.0
TDH Inactive L-threonine 3-dehydrogenase, mitochondrial (Short chain
dehydrogenase/reductase family 14E member 1 pseudogene)		 Homo sapiens
TI:9606 None
 
B7PZ94_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW020011 Threonine dehydrogenase, putative (EC 5.1.3.2) Ixodes scapularis
TI:6945 None
 
A0A0U9HSD7_KLENI
EnsemblPlants»
0.0
KFL_004670020 NAD-dependent epimerase/dehydratase Klebsormidium nitens
TI:105231 None
 
B1L4K5_KORCO
EnsemblBacteria»
0.0
Kcr_0631 NAD-dependent epimerase/dehydratase Korarchaeum cryptofilum
TI:498846 None
 
W5M3B5_LEPOC
Ensembl»
0.0
L-threonine 3-dehydrogenase, mitochondrial-like Lepisosteus oculatus
TI:7918 None
 
W5NJB1_LEPOC
Ensembl»
0.0
L-threonine 3-dehydrogenase, mitochondrial-like Lepisosteus oculatus
TI:7918 None
 
F7FPK9_MACMU
Ensembl»
0.0
TDH L-threonine dehydrogenase Macaca mulatta
TI:9544 None
   
F7G2B9_MONDO
Ensembl»
0.0
NAD-dependent epimerase/dehydratase
domain-containing protein		 Monodelphis domestica
TI:13616 None
   
TDH_MOUSE
Ensembl»
2.4
Tdh L-threonine 3-dehydrogenase,
mitochondrial (EC 1.1.1.103)		 Mus musculus
TI:10090 None
 
A7S4Q0_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g185634 NAD-dependent epimerase/dehydratase
domain-containing protein		 Nematostella vectensis
TI:45351 None
 
F6SMQ8_ORNAN
Ensembl»
0.0
LOC100074860 NAD-dependent epimerase/dehydratase
domain-containing protein		 Ornithorhynchus anatinus
TI:9258 None 		     
A0A3B3HU67_ORYLA
Ensembl»
0.0
LOC110013325 L-threonine 3-dehydrogenase, mitochondrial-like Oryzias latipes
TI:8090 None
   
H2MP55_ORYLA
Ensembl»
0.0
LOC101169257 L-threonine 3-dehydrogenase, mitochondrial Oryzias latipes
TI:8090 None
   
A0A2I3SIW5_PANTR
Ensembl»
0.0
TDH L-threonine dehydrogenase Pan troglodytes
TI:9598 None
 
H3G825_PHYRM
EnsemblProtists»
0.0
NAD-dependent epimerase/dehydratase
domain-containing protein		 Phytophthora ramorum
TI:164328 None
 
A0A454Y5I2_PRIPA
EnsemblMetazoa»
0.0
WBGene00092199 Epimerase Pristionchus pacificus
TI:54126 None 		 
 
D3ZN15_RAT
RGD»
2.5
Tdh L-threonine dehydrogenase Rattus norvegicus
TI:10116 None
   
B9TJ72_RICCO
EnsemblBacteria»
0.0
RCOM_1844620 Threonine dehydrogenase, putative Ricinus communis
TI:3988 None 		 
 
Y535_STAA8
EnsemblBacteria»
0.0
SAOUHSC_00535 Uncharacterized
epimerase/dehydratase SAOUHSC_00535		 Staphylococcus aureus
TI:1280 None
 
Q9K3F6_STRCO
EnsemblBacteria»
0.0
SCO1285 Ketoreductase Streptomyces coelicolor
TI:1902 None
 
A0A7M7PKS9_STRPU
EnsemblMetazoa»
0.0
NAD-dependent epimerase/dehydratase
domain-containing protein		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7SXR0_STRPU
EnsemblMetazoa»
0.0
NAD-dependent epimerase/dehydratase
domain-containing protein		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7T442_STRPU
EnsemblMetazoa»
0.0
L-threonine 3-dehydrogenase, mitochondrial Strongylocentrotus purpuratus
TI:7668 None
   
TDH_PIG
Ensembl»
0.0
TDH L-threonine 3-dehydrogenase,
mitochondrial (EC 1.1.1.103)		 Sus scrofa
TI:9823 None
 
B8BUH2_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_21300 NAD-dependent epimerase/dehydratase
domain-containing protein		 Thalassiosira pseudonana
TI:35128 None
 
A2DRV1_TRIV3
VEuPathDB»
0.0
TVAG_150490 NAD-dependent epimerase/dehydratase
domain-containing protein		 Trichomonas vaginalis
TI:5722 None
 
A2DU42_TRIV3
VEuPathDB»
0.0
TVAG_278010 NAD-dependent epimerase/dehydratase
domain-containing protein		 Trichomonas vaginalis
TI:5722 None
 
A2E8Y2_TRIV3
VEuPathDB»
0.0
TVAG_012320 Uncharacterized protein Trichomonas vaginalis
TI:5722 None
 
A2FSP3_TRIV3
VEuPathDB»
0.0
TVAG_441770 3-beta hydroxysteroid
dehydrogenase/isomerase domain-containing protein		 Trichomonas vaginalis
TI:5722 None
 
A2G174_TRIV3
VEuPathDB»
0.0
TVAG_304020 3-beta hydroxysteroid
dehydrogenase/isomerase domain-containing protein		 Trichomonas vaginalis
TI:5722 None
 
A2G175_TRIV3
VEuPathDB»
0.0
TVAG_304030 3-beta hydroxysteroid
dehydrogenase/isomerase domain-containing protein		 Trichomonas vaginalis
TI:5722 None
 
B3RV82_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_24631 NAD-dependent epimerase/dehydratase
domain-containing protein		 Trichoplax adhaerens
TI:10228 None
 
Q583Q5_TRYB2
VEuPathDB»
0.0
Tb06.5F5.290 L-threonine 3-dehydrogenase,
putative (EC 1.1.1.103)		 Trypanosoma brucei
TI:5691 None
 
A0A803KHH7_XENTR
Ensembl»
0.0
LOC101730350 L-threonine 3-dehydrogenase,
mitochondrial isoform X2		 Xenopus tropicalis
TI:8364 None 		 
 
A0A8J1KXP9_XENLA
Xenbase»
0.0
tdh.S L-threonine 3-dehydrogenase,
mitochondrial isoform X1		 Xenopus laevis
TI:8355 None
   
F7CLS9_XENTR
Xenbase»
0.0
tdh L-threonine 3-dehydrogenase, mitochondrial isoform
X1 (L-threonine dehydrogenase (pseudogene))		 Xenopus tropicalis
TI:8364 None