Collated Gene Ontology terms

Biological process: GTPase activator activity(2013, 2016, 2017, 2020, 2021, 2023) guanyl-nucleotide exchange factor activity(2023) small GTPase binding(2006)

Molecular function: signal transduction2023 regulation of Rho protein signal transduction2006, 2023 system development2023 cell development2023 regulation of small GTPase mediated signal transduction2023 defense response to virus2016 small GTPase mediated signal transduction2021 regulation of ARF protein signal transduction2023 imaginal disc-derived leg morphogenesis2012 apical constriction involved in gastrulation2016
Rho protein signal transduction2013

Cellular component: membrane2023 cytosol2013 cytoplasm2021 apical part of cell2016

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 2/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 1/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 0 2 4 6 8 10 Knownness

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
RHG20_HUMAN
Ensembl»
2.3
ARHGAP20 Rho GTPase-activating protein 20
(Rho-type GTPase-activating protein 20)		 Homo sapiens
TI:9606 None
 
TAGAP_HUMAN
Ensembl»
2.3
TAGAP T-cell activation Rho GTPase-activating
protein (T-cell activation GTPase-activating protein)		 Homo sapiens
TI:9606 None
 
A0A2I2ZPW0_GORGO
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Gorilla gorilla
TI:9593 None
 
B7PUH2_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW019271 Rho GTPase regulating protein, putative Ixodes scapularis
TI:6945 None
 
RHG20_RAT
RGD»
2.3
Arhgap20 Rho GTPase-activating protein 20 (RA and RhoGAP
domain-containing protein) (RARhoGAP) (Rho-type GTPase-activating protein 20)		 Rattus norvegicus
TI:10116 None
 
RHG20_MOUSE
Ensembl»
0.5
Arhgap20 Rho GTPase-activating protein 20 (RA and RhoGAP
domain-containing protein) (RARhoGAP) (Rho-type GTPase-activating protein 20)		 Mus musculus
TI:10090 None
 
TAGAP_MOUSE
Ensembl»
1.3
Tagap T-cell activation Rho GTPase-activating
protein (T-cell activation GTPase-activating protein)		 Mus musculus
TI:10090 None
 
W5MXS5_LEPOC
Ensembl»
0.0
Rho GTPase activating protein 20 Lepisosteus oculatus
TI:7918 None
 
T1EJ76_HELRO
EnsemblMetazoa»
0.0
20196626 Rho-GAP domain-containing protein Helobdella robusta
TI:6412 None
 
T1FDF3_HELRO
EnsemblMetazoa»
0.0
20206852 Rho-GAP domain-containing protein Helobdella robusta
TI:6412 None
 
T1FGL9_HELRO
EnsemblMetazoa»
0.0
20207968 Rho-GAP domain-containing protein Helobdella robusta
TI:6412 None
 
T1FGM0_HELRO
EnsemblMetazoa»
0.0
20207969 Rho-GAP domain-containing protein Helobdella robusta
TI:6412 None
 
TGAP1_MOUSE
Ensembl»
0.5
Tagap1 T-cell activation GTPase-activating protein 1 Mus musculus
TI:10090 None
   
W5NHV1_LEPOC
Ensembl»
0.0
T cell activation RhoGTPase activating protein Lepisosteus oculatus
TI:7918 None
 
A0A0D1DUS2_USTMA
EnsemblFungi»
0.0
UMAG_05326 SEC7 domain-containing protein Ustilago maydis
TI:5270 None
 
A0A139WCU6_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_34190 Rho GTPase-activating protein 20-like Protein Tribolium castaneum
TI:7070 None
 
A0A1S4H6T4_ANOGA
EnsemblMetazoa»
0.0
Uncharacterized protein Anopheles gambiae
TI:7165 None
 
A0A2A6CIX6_PRIPA
EnsemblMetazoa»
0.0
WBGene00205449 Rga-2 Pristionchus pacificus
TI:54126 None
 
A0A2I3RL56_PANTR
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Pan troglodytes
TI:9598 None
 
A0A8M9PSX5_DANRE
ZFIN»
0.5
arhgap20 Rho GTPase-activating protein 20 Danio rerio
TI:7955 None
 
A0JM05_XENTR
Xenbase»
0.0
arhgap20 Rho GTPase activating protein 20 Xenopus tropicalis
TI:8364 None
 
A7SC20_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g209966 Uncharacterized protein Nematostella vectensis
TI:45351 None
 
A8XIE2_CAEBR
WormBase»
0.0
rga-2 Protein CBR-RGA-2 Caenorhabditis briggsae
TI:6238 None
 
A9UXG0_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_24989 Rho-GAP domain-containing protein Monosiga brevicollis
TI:81824 None
 
B1N3W6_ENTH1
EnsemblProtists»
0.0
EHI_072080 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
B3RYA2_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_56489 Rho-GAP domain-containing protein Trichoplax adhaerens
TI:10228 None
 
B6ILK8_CAEBR
WormBase»
0.0
rga-9 Protein CBG25663 Caenorhabditis briggsae
TI:6238 None
 
B7Z058_DROME
FlyBase»
3.9
RhoGAP71E Rho GTPase activating protein at 71E, isoform D Drosophila melanogaster
TI:7227 None
 
B9EHI3_MOUSE
Ensembl»
0.5
1700006A11Rik 1700006A11Rik protein (RIKEN
cDNA 1700006A11 gene)		 Mus musculus
TI:10090 None
 
C4LSA7_ENTH1
EnsemblProtists»
0.0
EHI_153150 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4LSL1_ENTH1
EnsemblProtists»
0.0
EHI_151700 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4LT12_ENTH1
EnsemblProtists»
0.0
EHI_148420 Rho-GAP domain-containing protein Entamoeba histolytica
TI:5759 None
 
C4LT51_ENTH1
EnsemblProtists»
0.0
EHI_148840 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4LTC3_ENTH1
EnsemblProtists»
0.0
EHI_045100 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4LUF8_ENTH1
EnsemblProtists»
0.0
EHI_049570 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4LV70_ENTH1
EnsemblProtists»
0.0
EHI_182930 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4LVA5_ENTH1
EnsemblProtists»
0.0
EHI_182500 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4LVB4_ENTH1
EnsemblProtists»
0.0
EHI_196960 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4LWK5_ENTH1
EnsemblProtists»
0.0
EHI_069170 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4LY00_ENTH1
EnsemblProtists»
0.0
EHI_035710 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4LZS4_ENTH1
EnsemblProtists»
0.0
EHI_039030 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4M1X2_ENTH1
EnsemblProtists»
0.0
EHI_164790 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4M676_ENTH1
EnsemblProtists»
0.0
EHI_117610 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4M8N2_ENTH1
EnsemblProtists»
0.0
EHI_114370 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4MBC3_ENTH1
EnsemblProtists»
0.0
EHI_011070 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
C4MBR1_ENTH1
EnsemblProtists»
0.0
EHI_171170 RhoGAP domain containing protein Entamoeba histolytica
TI:5759 None
 
D2A378_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_07566 Rho-GAP domain-containing protein Tribolium castaneum
TI:7070 None
 
D3ZXG5_RAT
RGD»
1.0
Tagap T-cell activation RhoGTPase activating protein Rattus norvegicus
TI:10116 None
 
E9FRQ4_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_219940 Rho-GAP domain-containing protein Daphnia pulex
TI:6669 None
 
E9G1S3_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_44312 Rho-GAP domain-containing protein Daphnia pulex
TI:6669 None
 
F1Q8C7_DANRE
ZFIN»
0.5
zgc:77799 T cell activation RhoGTPase-activating protein a
(T-cell activation Rho GTPase-activating protein isoform X1)		 Danio rerio
TI:7955 None
 
G3QPM6_GORGO
Ensembl»
0.0
TAGAP T cell activation RhoGTPase activating protein Gorilla gorilla
TI:9593 None
 
H2QTZ3_PANTR
Ensembl»
0.0
TAGAP T cell activation RhoGTPase activating protein Pan troglodytes
TI:9598 None
 
M3W3U9_FELCA
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Felis catus
TI:9685 None
 
M3WL65_FELCA
Ensembl»
0.0
TAGAP T cell activation RhoGTPase activating protein Felis catus
TI:9685 None
 
M3X8G6_FELCA
Ensembl»
0.0
Rho-GAP domain-containing protein Felis catus
TI:9685 None
 
Q08DB1_BOVIN
Ensembl»
0.0
TAGAP T cell activation RhoGTPase activating
protein (T-cell activation GTPase activating protein)		 Bos taurus
TI:9913 None
 
Q3V0P3_MOUSE
Ensembl»
0.5
Gm1527 Predicted gene 1527 Mus musculus
TI:10090 None
 
Q9XW53_CAEEL
WormBase»
0.5
rga-2 Rho GTPase-activating protein 20 Caenorhabditis elegans
TI:6239 None
 
U4PAK0_CAEEL
WormBase»
0.5
rga-9 Rho-GAP domain-containing protein Caenorhabditis elegans
TI:6239 None
 
W5NBM3_LEPOC
Ensembl»
0.0
Rho-GAP domain-containing protein Lepisosteus oculatus
TI:7918 None
 
A0A0G2K665_RAT
RGD»
0.5
Tgap1 GTPase activating protein testicular GAP1 Rattus norvegicus
TI:10116 None
   
A0A0G2K6E6_RAT
RGD»
0.5
LOC120093152 Similar to T-cell activation
Rho GTPase-activating protein isoform b		 Rattus norvegicus
TI:10116 None
   
A0A0G2K7I7_RAT
RGD»
0.0
AABR07010672.1 PH domain-containing protein Rattus norvegicus
TI:10116 None 		     
A0A3Q1M2Q1_BOVIN
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Bos taurus
TI:9913 None
   
A0A3Q2GW36_HORSE
Ensembl»
0.0
Rho-GAP domain-containing protein Equus caballus
TI:9796 None
   
A0A5F8HFV5_MONDO
Ensembl»
0.0
T cell activation RhoGTPase activating protein Monodelphis domestica
TI:13616 None 		       
A0A6I8N785_ORNAN
Ensembl»
0.0
LOC103167849 Rho-GAP domain-containing protein Ornithorhynchus anatinus
TI:9258 None
   
A0A6I8NB09_ORNAN
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Ornithorhynchus anatinus
TI:9258 None
   
A0A6I8NZ97_ORNAN
Ensembl»
0.0
Rho-GAP domain-containing protein Ornithorhynchus anatinus
TI:9258 None
   
A0A6I8QXZ0_XENTR
Xenbase»
0.0
arhgap20b Rho GTPase-activating protein 20 Xenopus tropicalis
TI:8364 None
   
A0A7M7HP66_STRPU
EnsemblMetazoa»
0.0
Rho GTPase-activating protein 20 Strongylocentrotus purpuratus
TI:7668 None
   
A0A8I3MU89_CANLF
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Canis lupus
TI:9612 None
   
A0A8I3NVD9_CANLF
Ensembl»
0.0
Rho-GAP domain-containing protein Canis lupus
TI:9612 None
   
A0A8I3P8K9_CANLF
Ensembl»
0.0
Rho-GAP domain-containing protein Canis lupus
TI:9612 None
   
A0A8I3P9Q8_CANLF
Ensembl»
0.0
Rho-GAP domain-containing protein Canis lupus
TI:9612 None
   
A0A8I3PBG2_CANLF
Ensembl»
0.0
Rho-GAP domain-containing protein Canis lupus
TI:9612 None
   
A0A8I3PIB8_CANLF
Ensembl»
0.0
LOC119864445 Rho GTPase activating protein 20 Canis lupus
TI:9612 None
   
A0A8I3RRI3_CANLF
Ensembl»
0.0
TAGAP T cell activation RhoGTPase activating protein Canis lupus
TI:9612 None
   
A0A8I5Y886_RAT
RGD»
0.0
LOC102550446 Rho GTPase-activating protein 20-like Rattus norvegicus
TI:10116 None
   
A0A8I5YCI0_RAT
RGD»
0.0
RGD1306704 Hypothetical LOC295483 Rattus norvegicus
TI:10116 None 		     
A0A8I5ZV48_RAT
RGD»
0.0
LOC120100815 Rho GTPase-activating protein 20-like Rattus norvegicus
TI:10116 None
   
A0A8I5ZY49_RAT
RGD»
0.0
LOC102555991 Uncharacterized LOC102555991 Rattus norvegicus
TI:10116 None
   
A0A8I6AIQ0_RAT
RGD»
0.5
RGD1563562 Similar to GTPase
activating protein testicular GAP1		 Rattus norvegicus
TI:10116 None
   
A0A8I6GKX2_RAT
RGD»
0.0
LOC678817 Similar to GTPase
activating protein testicular GAP1		 Rattus norvegicus
TI:10116 None
   
A0A8J0SP67_XENTR
Xenbase»
0.0
tagap T-cell activation Rho
GTPase-activating protein isoform X1		 Xenopus tropicalis
TI:8364 None
   
A0A8M1REZ7_DANRE
CTD»
0.0
arhgap20b Rho GTPase-activating protein 20 isoform X1 Danio rerio
TI:7955 None
   
A0A8M3AT33_DANRE
CTD»
0.0
tagapb T-cell activation Rho
GTPase-activating protein isoform X1		 Danio rerio
TI:7955 None
   
A0A8R1UG62_PRIPA
EnsemblMetazoa»
0.0
WBGene00112295 Rho-GAP domain-containing protein Pristionchus pacificus
TI:54126 None
   
A0A8V0XGK1_CHICK
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Gallus gallus
TI:9031 None
   
A0A8V0XV08_CHICK
Ensembl»
0.0
TAGAP T cell activation RhoGTPase activating protein Gallus gallus
TI:9031 None
   
A0A8V0YYS2_CHICK
Ensembl»
0.0
ARHGAP20B Rho-GAP domain-containing protein Gallus gallus
TI:9031 None
   
A0A9J7LP40_BRAFL
CTD»
0.0
LOC118422840 Uncharacterized protein LOC118422840 isoform X1 Branchiostoma floridae
TI:7739 None
   
D3Z8H5_RAT
RGD»
0.5
AABR07010333.1 Rho-GAP domain-containing protein Rattus norvegicus
TI:10116 None
   
D3ZRJ5_RAT
RGD»
0.5
AABR07009260.1 Uncharacterized LOC100910852 Rattus norvegicus
TI:10116 None
   
D4AA19_RAT
RGD»
0.5
RGD1306519 Rho-GAP domain-containing protein Rattus norvegicus
TI:10116 None
   
E9PTA9_RAT
RGD»
0.0
LOC100910852 Uncharacterized LOC100910852 Rattus norvegicus
TI:10116 None
   
F1M6I1_RAT
RGD»
0.5
LOC691033 Similar to GTPase
activating protein testicular GAP1		 Rattus norvegicus
TI:10116 None
   
F1M6I2_RAT
RGD»
0.5
LOC499607 Similar to GTPase
activating protein testicular GAP1		 Rattus norvegicus
TI:10116 None
   
F1S1S8_PIG
Ensembl»
0.0
Uncharacterized protein Sus scrofa
TI:9823 None
   
F1SB58_PIG
Ensembl»
0.0
TAGAP T cell activation RhoGTPase activating protein Sus scrofa
TI:9823 None
   
F6ZP42_MACMU
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Macaca mulatta
TI:9544 None
   
F7ALC2_HORSE
Ensembl»
0.0
Rho-GAP domain-containing protein Equus caballus
TI:9796 None
   
F7BJJ5_ORNAN
Ensembl»
0.0
T cell activation RhoGTPase activating protein Ornithorhynchus anatinus
TI:9258 None 		       
F7CPC8_MONDO
Ensembl»
0.0
Rho-GAP domain-containing protein Monodelphis domestica
TI:13616 None
   
F7F3K8_MONDO
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Monodelphis domestica
TI:13616 None
   
F7H213_MACMU
Ensembl»
0.0
TAGAP T cell activation RhoGTPase activating protein Macaca mulatta
TI:9544 None
   
G1K9D8_ANOCA
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Anolis carolinensis
TI:28377 None
   
G1KCY3_ANOCA
Ensembl»
0.0
TAGAP T cell activation RhoGTPase activating protein Anolis carolinensis
TI:28377 None
   
H2M9K0_ORYLA
Ensembl»
0.0
LOC101155816 T-cell activation Rho GTPase-activating protein Oryzias latipes
TI:8090 None
   
H2MBS6_ORYLA
Ensembl»
0.0
LOC101155476 Rho GTPase-activating protein 20 Oryzias latipes
TI:8090 None
   
H9G7S8_ANOCA
Ensembl»
0.0
LOC103280657 Uncharacterized protein Anolis carolinensis
TI:28377 None
   
I3LKJ5_PIG
Ensembl»
0.0
ARHGAP20 Rho GTPase activating protein 20 Sus scrofa
TI:9823 None
   
J3QPK7_MOUSE
Ensembl»
0.0
1700003H04Rik RIKEN cDNA 1700003H04 gene Mus musculus
TI:10090 None